Immunogenicity, Effectiveness, and Safety of COVID-19 Vaccines among Patients with Immune-Mediated Dermatological Diseases: A Systematic Review and Meta-analysis
In conclusion, immune-mediated dermatological diseases showed a reduced vaccine response in our meta-analysis, yet vaccination remained effective against COVID-19 infection and well tolerated.PMID:38698654 | DOI:10.2340/actadv.v104.40009 (Source: Acta Dermato-Venereologica)
Source: Acta Dermato-Venereologica - May 3, 2024 Category: Dermatology Authors: Sonphet Chirasuthat Yanisa Ratanapokasatit Kunlawat Thadanipon Kumutnart Chanprapaph Source Type: research

Modeling and predicting individual variation in COVID-19 vaccine-elicited antibody response in the general population
PLOS Digit Health. 2024 May 3;3(5):e0000497. doi: 10.1371/journal.pdig.0000497. eCollection 2024 May.ABSTRACTAs we learned during the COVID-19 pandemic, vaccines are one of the most important tools in infectious disease control. To date, an unprecedentedly large volume of high-quality data on COVID-19 vaccinations have been accumulated. For preparedness in future pandemics beyond COVID-19, these valuable datasets should be analyzed to best shape an effective vaccination strategy. We are collecting longitudinal data from a community-based cohort in Fukushima, Japan, that consists of 2,407 individuals who underwent serum sam...
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Naotoshi Nakamura Yurie Kobashi Kwang Su Kim Hyeongki Park Yuta Tani Yuzo Shimazu Tianchen Zhao Yoshitaka Nishikawa Fumiya Omata Moe Kawashima Makoto Yoshida Toshiki Abe Yoshika Saito Yuki Senoo Saori Nonaka Morihito Takita Chika Yamamoto Takeshi Kawamura Source Type: research

Challenges and solutions to system-wide use of precision oncology as the standard of care paradigm
Camb Prism Precis Med. 2024 Mar 26;2:e4. doi: 10.1017/pcm.2024.1. eCollection 2024.ABSTRACTThe personalised oncology paradigm remains challenging to deliver despite technological advances in genomics-based identification of actionable variants combined with the increasing focus of drug development on these specific targets. To ensure we continue to build concerted momentum to improve outcomes across all cancer types, financial, technological and operational barriers need to be addressed. For example, complete integration and certification of the 'molecular tumour board' into 'standard of care' ensures a unified clinical de...
Source: Cancer Control - May 3, 2024 Category: Cancer & Oncology Authors: Nesrine Lajmi Sofia Alves-Vasconcelos Apostolos Tsiachristas Andrew Haworth Kerrie Woods Charles Crichton Theresa Noble Hizni Salih Kinga A V árnai Harriet Branford-White Liam Orrell Andrew Osman Kevin M Bradley Lara Bonney Daniel R McGowan Jim Davies Ma Source Type: research

High-Risk Human Papilloma Virus Genotype Distribution and Correlation with Cervical Cytomorphological Data in Turkish and Immigrant Women in Mersin Province
New Microbiol. 2024 May;47(1):88-97.ABSTRACTHuman papilloma virus (HPV) is the most common sexually transmitted viral agent in the world and the most common cause of cervical cancer. HPV prevalence and genotype distribution vary by region and demographic data. In a province in the south of Turkey that constantly receives immigration, we aimed to determine the prevalence of high-risk HPV (HR-HPV) genotypes, evaluate the compatibility between cervical Pap smear cytology results patients and HR-HPVs, and make an up-to-date contribution to the elucidation of epidemiological data. In this single-centre study, a total of 12,641 ...
Source: New Microbiologica - May 3, 2024 Category: Microbiology Authors: Murat Yaman Hacer Ece Arslan Özcan Ayfer Bakir Source Type: research

Health status and public health needs in a Togolese child health care centre modelled after the Dutch system
CONCLUSION: A large group of children in need of prevention and early treatment were detected, informed and treated by the centre. Further research is needed to confirm if this strategy can improve children's health in Sub-Saharan Africa. Our data are available for further research.PMID:38700227 | DOI:10.1080/03014460.2024.2342529 (Source: Annals of Human Biology)
Source: Annals of Human Biology - May 3, 2024 Category: Biology Authors: Paula van Dommelen C écile Schat-Savy Arjan Huizing Symone Detmar Leonhard A Bakker Paul H Verkerk Source Type: research

A review and new perspective on oral bacteriophages: manifestations in the ecology of oral diseases
CONCLUSION: Due to their intricate interactions with bacteria and oral cells, bacteriophages are closely linked to the progression and regression of diverse oral diseases. And there is an urgent need for research to explore additional possibilities of bacteriophages in the management of oral diseases.PMID:38698893 | PMC:PMC11064738 | DOI:10.1080/20002297.2024.2344272 (Source: Journal of Oral Microbiology)
Source: Journal of Oral Microbiology - May 3, 2024 Category: Microbiology Authors: Xinyu Guo Xiaowan Wang Jia Shi Jiayi Ren Jumei Zeng Jinquan Li Yuqing Li Source Type: research

A cleaved adhesin DNA vaccine targeting dendritic cell against Porphyromonas gingivalis –induced periodontal disease
ConclusionsThe co-administration of a CCL19-conjugated CA DNA vaccine holds promise as an innovative and targeted immunization strategy againstP. gingivalis–induced periodontitis and peri-implantitis. (Source: Molecular Oral Microbiology)
Source: Molecular Oral Microbiology - May 3, 2024 Category: Microbiology Authors: Xin Fan, Peng ‐Yu Qu, Ke‐Feng Luan, Chen‐Yu Sun, Hui‐Ping Ren, Xue‐Hui Sun, Jing Lan Tags: ORIGINAL ARTICLE Source Type: research

Daily briefing: Orangutan is first wild animal seen using medicinal plant
Nature, Published online: 03 May 2024; doi:10.1038/d41586-024-01348-2A Sumatran orangutan nicknamed Rakus treated a gash in his cheek with a poultice. Plus, a promising vaccine for urinary tract infections and a special collection on sex and gender in research. (Source: Nature AOP)
Source: Nature AOP - May 3, 2024 Category: Research Authors: Flora Graham Source Type: research

Driving delivery and uptake of catch-up vaccination among adolescent and adult migrants in UK general practice: a mixed methods pilot study
Migrants in the UK and Europe face vulnerability to vaccine-preventable diseases (VPDs) due to missed childhood vaccines and doses and marginalisation from health systems. Ensuring migrants receive catch-up va... (Source: BMC Medicine)
Source: BMC Medicine - May 3, 2024 Category: Internal Medicine Authors: Alison F. Crawshaw, Lucy P. Goldsmith, Anna Deal, Jessica Carter, Felicity Knights, Farah Seedat, Karen Lau, Sally E. Hayward, Joanna Yong, Desiree Fyle, Nathaniel Aspray, Michiyo Iwami, Yusuf Ciftci, Fatima Wurie, Azeem Majeed, Alice S. Forster & hellip; Tags: Research article Source Type: research

Development of novel Streptococcus equi vaccines with an assessment of their immunizing potentials and protective efficacies
Strangles is a highly contagious disease of the equine upper respiratory tract caused by Streptococcus equi subspecies. Streptococcus equi subsp. equi (S. equi) and Streptococcus equi subsp. zooepidemicus (S. zoo... (Source: BMC Veterinary Research)
Source: BMC Veterinary Research - May 3, 2024 Category: Veterinary Research Authors: Rafik Soliman, Mohamed Yousef, Sara Abdel gelil and Hassan Aboul-Ella Tags: Research Source Type: research

Direct impact of COVID-19 vaccination in Chile: averted cases, hospitalizations, ICU admissions, and deaths
This study aims to asses... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - May 3, 2024 Category: Infectious Diseases Authors: Antoine Brault, Andrew Hart, Paula Uribe, Jorge Prado, Jaime San Mart ín, Alejandro Maass and Mauricio Canals Tags: Research Source Type: research

Low HBV knowledge is associated with low HBV vaccination uptake in general adult population despite incentivization of HBV vaccination
Hepatitis B virus (HBV) vaccination in Vietnamese adults remains low and unequally distributed. We conducted a study on HBV-na ïve adults living in Ho Chi Minh City, Viet Nam, to determine barriers associated w... (Source: BMC Infectious Diseases)
Source: BMC Infectious Diseases - May 3, 2024 Category: Infectious Diseases Authors: Thanh Van Kim, Trang Ngoc Doan Pham, Brian Do, Diem Vu Bich Dao, Dan Xuan Nguyen, William Lee, Robert Gish, Gary Mize, Amy Trang, Anh Le, Loc Thi Bich Phan, Thi-Thuy-Dung Ngo, Hai Thanh Phan, Binh Tan Nguyen, Hong Kim Tang and Doan Y Dao Tags: Research Source Type: research

Immunologic responses to the third and fourth doses of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) vaccines in cell therapy recipients: a systematic review and meta-analysis
Multiple studies have provided evidence of suboptimal or poor immune responses to SARS-CoV-2 vaccines in recipients of hematopoietic stem cell transplantation (HSCT) and chimeric antigen receptor-T (CAR-T) cel... (Source: Virology Journal)
Source: Virology Journal - May 3, 2024 Category: Virology Authors: Leyla Sharifi Aliabadi, Mojtaba Azari, Mohammad Reza Taherian, Maryam Barkhordar, Syed Aon Mehdi Abbas, Morteza Azari, Mohammad Ahmadvand, Zahra Salehi, Shiva Rouzbahani and Mohammad Vaezi Tags: Review Source Type: research

Epidemiological and health economic implications of symptom propagation in respiratory pathogens: A mathematical modelling investigation
ConclusionsOverall, the preferred intervention type depended on the combination of the strength of symptom propagation and uptake. Given the importance of determining robust public health responses, we highlight the need to gather further data on symptom propagation, with our modelling framework acting as a template for future analysis. (Source: PLoS Computational Biology)
Source: PLoS Computational Biology - May 3, 2024 Category: Biology Authors: Phoebe Asplin Source Type: research

Global research trends in CAR-T cell therapy for solid tumors: A comprehensive visualization and bibliometric study (2012 –2023)
Volume 20, Issue 1, December 2024 . (Source: Human Vaccines and Immunotherapeutics)
Source: Human Vaccines and Immunotherapeutics - May 3, 2024 Category: Allergy & Immunology Authors: Lele MiaoJuan ZhangWei XuQian QianGuochao ZhangQuan YuanYuetao LvHaiguo ZhangChaoyan ShenWei Wanga Department of Thyroid and Breast Surgery, Jining NO.1 People ’s Hospital, Jining, Chinab Department of Hematology, Jining NO.1 People’s Hospital, Jining Source Type: research