Toxic Shock Syndrome Research This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Importance of toxin genes and polymerase chain reaction-based open reading frame type (POT) analysis for severe Staphylococcus aureus infection in children
Jpn J Infect Dis. 2023 Aug 31. doi: 10.7883/yoken.JJID.2023.194. Online ahead of print.ABSTRACTIn the present study, 26 Staphylococcus aureus strains, including 16 methicillin-resistant S. aureus (MRSA) and 10 methicillin-susceptible S. aureus (MSSA), which were collected from eight medical institutions in Chiba Prefecture that requested toxin gene analysis from 2015 to 2021, were analyzed. A total of 14 Panton-Valentine leukocidin (PVL) positive strains were identified, including one of MSSA. PVL-positive strains were classified into seven types based on polymerase chain reaction-based open reading frame typing (POT). Of ...
Source: Japanese Journal of Infectious Diseases - August 30, 2023 Category: Infectious Diseases Authors: Noriko Takeuchi Naruhiko Ishiwada Source Type: research

Effectiveness of Intravenous Immunoglobulin Therapy for Invasive Group A Streptococcus Infection: A Japanese Nationwide Observational Study
Group A Streptococcus (GAS) is a Gram-positive, beta-hemolytic coccus. It can cause various diseases, ranging from mild illnesses (such as pharyngitis and impetigo) to severe illnesses (such as necrotizing fasciitis and streptococcal toxic shock syndrome (STSS)). Invasive group A Streptococcus infection (iGAS) is defined as the isolation of GAS from sterile sites including the blood, pleura, and cerebrospinal fluid [1]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - August 14, 2023 Category: Infectious Diseases Authors: Atsushi Senda, Akira Endo, Kiyohide Fushimi, Yasuhiro Otomo Source Type: research

Streptococcal Toxic Shock Syndrome caused by Streptococcus dysgalactiae subsp. equisimilis-related Empyema: A Novel Case Report
Intern Med. 2023 Aug 9. doi: 10.2169/internalmedicine.2254-23. Online ahead of print.ABSTRACTStreptococcal toxic shock syndrome (STSS) caused by Streptococcus dysgalactiae subsp. equisimilis (SDSE)-related empyema is rare but can result in shock vitals, acute kidney injury, and extensive erythema. In the present case, a 92-year-old woman with empyema caused by SDSE developed STSS after pleural drainage and antibiotic therapy. Despite temporary improvement with clindamycin and pleural drainage, the patient ultimately died due to malnutrition. Autopsy findings suggested that the infection was well controlled, but infections ...
Source: Internal Medicine - August 9, 2023 Category: Internal Medicine Authors: Kazuhiko Iwasaki Ryo Okino Akihito Okazaki Masa-Aki Kawashiri Source Type: research

Managing tandem breastfeeding during acute hospitalization: A case study
This case study presents a mother who continued tandem breastfeeding throughout the acute admission of her critically ill newborn. Her younger child, the subject of this case report was admitted to our hospital with septic shock and progressing bullous scalp lesions. The infant had streptococcal toxic shock syndrome and necrotizing fasciitis of the scalp due to streptococcus pyogenes. The infant required immediate life-sustaining interventions, followed by weekly surgical procedures which meant the infant had brief periods of intravenous nutrition surrounding the time of anesthesia administration. (Source: Journal of Pediatric Nursing)
Source: Journal of Pediatric Nursing - August 4, 2023 Category: Nursing Authors: Lisa G. Dell, Diane L. Spatz Source Type: research

Invasive Group A streptococcal infections: are we facing a new outbreak? A case series with the experience of a single tertiary center
ConclusionsAccurate differential diagnosis and early treatment both could help to reduce the transmission of GAS and consequently the risk of severe iGAS. These cases confirmed the need for close monitoring and appropriate notification, in order to verify their actual increased incidence. (Source: Italian Journal of Pediatrics)
Source: Italian Journal of Pediatrics - July 19, 2023 Category: Pediatrics Source Type: research

Acute kidney injury in pediatric toxic shock syndrome is associated with worse clinical course in the intensive care unit
Conclusion: Children admitted to the PICU with TSS, show a high prevalence of AKI at presentation. Creatinine levels and clearance normalize by hospital discharge in most cases. AKI in the setting of TSS could be used as an early marker for illness severity and a predictor of a more complex course.What is Known:• TSS is characterized according to the CDC by specific sets of clinical signs and symptoms in conjunction with specific laboratory findings one of which is AKI.• AKI is associated with worse outcomes in critically ill patients in general and in septic patients in particular.What is New:• AKI is found in about...
Source: European Journal of Pediatrics - July 17, 2023 Category: Pediatrics Source Type: research

SARS-CoV-2 Antibody Titers and Severity of Multisystem Inflammatory Syndrome in Children
CONCLUSION: Therefore, it might not be appropriate to predict the clinical course of patients presenting with MISC based on quantitative serology testing.PMID:37437945 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - July 12, 2023 Category: Laboratory Medicine Authors: Miray Kurtca Anil K Chokkalla Sridevi Devaraj Source Type: research