Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Association of CovRS two-component regulatory system with NADase induction by Clindamycin treatment in Streptococcus pyogenes
Jpn J Infect Dis. 2024 Mar 29. doi: 10.7883/yoken.JJID.2023.451. Online ahead of print.ABSTRACTThe administration of high-dose clindamycin (CLI) along with penicillin is recommended for the treatment of streptococcal toxic shock syndrome (STSS). However, CLI-resistant strains have been identified worldwide. Firstly, in this study, some CLI-resistant strains showed increased extracellular activities of the NAD- glycohydrolase (NADase) exotoxin after CLI treatment. This result supported our previous conclusion that not only CLI-susceptible but also CLI-resistant S. pyogenes strains show the CLI-dependent NADase induction. Se...
Source: Japanese Journal of Infectious Diseases - March 31, 2024 Category: Infectious Diseases Authors: Ichiro Tatsuno Masanori Isaka Tadao Hasegawa Source Type: research

Antimicrobial resistance and virulence profiling of < em > Staphylococcus pseudintermedius < /em > isolated from cats, Bangladesh
The objectives of the cross-sectional study were to estimate the prevalence, antimicrobial resistance pattern, and detection of diverse resistance as well as virulence genes of S. pseudintermedius in cats. A standard bacteriological method, species-specific gene and different antimicrobial resistance as well as virulence genes were confirmed by PCR assay. A total of 233 swab samples were collected from different body sites of 102 cats, among them 146 swabs from 73 healthy cats, and 87 from 29 diseased cats. Overall, prevalence of S. pseudintermedius in cats was 12.01%, while dermatitis and otitis affected cats were 26.08% ...
Source: Veterinary Quarterly - March 15, 2024 Category: Veterinary Research Authors: Eaftekhar Ahmed Rana Tanvir Ahmad Nizami Md Sayedul Islam Subrata Sarker Hafizar Rahman Azizul Hoque Mizanur Rahman Source Type: research

Health benefits of combined oral contraceptives - a narrative review
CONCLUSIONS: The use of combined oral contraceptives is accompanied with a range of health benefits, to be balanced against its side-effects and risks. Several health benefits of COCs are a reason for non-contraceptive COC prescription.PMID:38426312 | DOI:10.1080/13625187.2024.2317295 (Source: The European Journal of Contraception and Reproductive Health Care)
Source: The European Journal of Contraception and Reproductive Health Care - March 1, 2024 Category: Reproduction Medicine Authors: Herjan J T Coelingh Bennink Femke A M van Gennip Mireille G F Gerrits Jan F M Egberts Kristina Gemzell-Danielsson Helena Kopp-Kallner Source Type: research