SARS-CoV-2 Antibody Titers and Severity of Multisystem Inflammatory Syndrome in Children
CONCLUSION: Therefore, it might not be appropriate to predict the clinical course of patients presenting with MISC based on quantitative serology testing.PMID:37437945 (Source: Annals of Clinical and Laboratory Science)
Source: Annals of Clinical and Laboratory Science - July 12, 2023 Category: Laboratory Medicine Authors: Miray Kurtca Anil K Chokkalla Sridevi Devaraj Source Type: research

Overlapping Presentation of Group A Streptococcus and Upper Respiratory Infection  in a Pediatric Patient: A Case Report
Group A streptococcus (GAS), a gram-positive bacteria, is the most common bacterial etiology in acute pharyngitis, accounting for 20% to 30% of all pediatric cases (Ashurst& Edgerley-Gibb, 2022). GAS pharyngitis is a risk of subsequent complications, including acute glomerulonephritis, streptococcal toxic shock syndrome, and acute rheumatic fever, if not recognized and treated promptly (Centers for Disease Control and Prevention [CDC], 2023). Worldwide, GAS pharyngitis is estimated at nearly 288 million episodes annually in children aged 5 –14 years (Miller et al., 2022). (Source: Journal of Pediatric Health Care)
Source: Journal of Pediatric Health Care - July 8, 2023 Category: Pediatrics Authors: Emily Menting, Traci R. Snedden Tags: Case Report Source Type: research

Clinical significance of serum cytokine profiles for differentiating between Kawasaki disease and its mimickers
CONCLUSION: Serum cytokine profiles may be useful for differentiating between KD and its mimickers.PMID:37356260 | DOI:10.1016/j.cyto.2023.156280 (Source: Cytokine)
Source: Cytokine - June 25, 2023 Category: Molecular Biology Authors: Shuya Kaneko Masaki Shimizu Asami Shimbo Hitoshi Irabu Koji Yokoyama Kenji Furuno Takayuki Tanaka Kazuyuki Ueno Shuhei Fujita Naomi Iwata Junya Fujimura Keiji Akamine Mao Mizuta Yasuo Nakagishi Toshinori Minato Kenichi Watanabe Anna Kobayashi Takuya Endo Source Type: research

Clinical significance of serum cytokine profiles for differentiating between Kawasaki disease and its mimickers
CONCLUSION: Serum cytokine profiles may be useful for differentiating between KD and its mimickers.PMID:37356260 | DOI:10.1016/j.cyto.2023.156280 (Source: Cytokine)
Source: Cytokine - June 25, 2023 Category: Molecular Biology Authors: Shuya Kaneko Masaki Shimizu Asami Shimbo Hitoshi Irabu Koji Yokoyama Kenji Furuno Takayuki Tanaka Kazuyuki Ueno Shuhei Fujita Naomi Iwata Junya Fujimura Keiji Akamine Mao Mizuta Yasuo Nakagishi Toshinori Minato Kenichi Watanabe Anna Kobayashi Takuya Endo Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - June 15, 2023 Category: Drugs & Pharmacology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: Molecular Medicine)
Source: Molecular Medicine - June 15, 2023 Category: Molecular Biology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: Pharmacological Reviews)
Source: Pharmacological Reviews - June 15, 2023 Category: Drugs & Pharmacology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - June 15, 2023 Category: Drugs & Pharmacology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: Molecular Medicine)
Source: Molecular Medicine - June 15, 2023 Category: Molecular Biology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Revolutionizing treatment for toxic shock syndrome with engineered super chromones to combat antibiotic-resistant Staphylococcus aureus
CONCLUSIONS: This study suggests that chromones can be engineered to develop effective drugs against TSS caused by S. aureus. The optimized compound has the potential to be a promising therapeutic agent for the treatment of TSS, providing new hope for patients suffering from this life-threatening disease of toxic shock syndrome.PMID:37318504 | DOI:10.26355/eurrev_202306_32649 (Source: European Review for Medical and Pharmacological Sciences)
Source: European Review for Medical and Pharmacological Sciences - June 15, 2023 Category: Drugs & Pharmacology Authors: M Naveed N Ain T Aziz I Ali M Aqib Shabbir K Javed M Alharbi A Alshammari A F Alasmari Source Type: research

Surveillance of non-invasive group A Streptococcus infections in French ambulatory pediatrics before and during the COVID-19 pandemic: a prospective multicenter study from 2018 to 2022
Group A Streptococcus (GAS) can cause a wider variety of diseases than any other bacterial species, ranging from mild throat and skin infections to uncommon but life-threatening invasive diseases such as streptococcal toxic shock syndrome, necrotizing fasciitis, or bacteremia [1, 11]. The most common GAS infection in ambulatory pediatrics is tonsillopharyngitis (i.e., “strep throat”) [11]. In many countries, the diagnosis of GAS tonsillopharyngitis has been facilitated with the use of rapid antigen detection tests (RADTs) [Suppl 1]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - June 5, 2023 Category: Infectious Diseases Authors: Pr J érémie F. Cohen, Dr Alexis Rybak, Dr Andreas Werner, Dr Fabienne Kochert, Dr Fabienne Cahn-Sellem, Dr Nathalie Gelbert, Dr François Vié Le Sage, Dr Christophe Batard, Mr Stéphane Béchet, Dr Hippolyte Corbaux, Dr Bruno Frandji, Dr Corinne Levy, Source Type: research