Acute abdomen: a rare presentation of group a streptococcal infection
Acta Chir Belg. 2022 Jun 30:1-4. doi: 10.1080/00015458.2022.2040108. Online ahead of print.ABSTRACTIn this case report we describe a 38-year old female patient admitted to the emergency department with acute abdomen and sepsis. Broad-spectrum antibiotics were started. Abdominal imaging was inconclusive, exploratory laparoscopy showed four-quadrant peritonitis. No provoking factor could be withheld. Due to clinical deterioration the patient was transferred to the intensive care unit. Blood cultures showed the presence of group A streptococcus, and clindamycin was associated. She recovered, and could be discharged after seve...
Source: Acta Chirurgica Belgica - July 1, 2022 Category: Surgery Authors: Jelle Lubach Marie Vannijvel Hendrik Stragier Yves Debaveye Albert Wolthuis Source Type: research

GSE124756 Comparison of Transcriptional Signatures of Three Staphylococcal Superantigenic Toxins in Human Epidermal Melanocytes
Contributors : Seshamalini Srinivasan ; Nabarun Chakraborty ; Ruoting Yang ; Stacy Ann-Miller ; Aarti Gautam ; Abdulnaser Alkhalil ; Lauren T Moffatt ; Bonnie C Carney ; Marti Jett ; Jeffrey W Shupp ; Rasha Hammamieh ; Marti JettSeries Type : Expression profiling by arrayOrganism : Homo sapiensStaphylococcus aureus, a gram-positive bacterium, causes food poisoning and toxic shock syndrome through the production of superantigenic toxins known as Staphylococcal enterotoxins serotypes A-J (SEA, SEB, etc.) and toxic shock syndrome toxin-1 (TSST-1). A subset of these toxins have been classified as potential biothreat a...
Source: GEO: Gene Expression Omnibus - June 30, 2022 Category: Genetics & Stem Cells Tags: Expression profiling by array Homo sapiens Source Type: research

Bacteriophage Therapy for Staphylococcus Aureus Infections: A Review of Animal Models, Treatments, and Clinical Trials
Staphylococcus aureus (S. aureus) is a common and virulent human pathogen causing several serious illnesses including skin abscesses, wound infections, endocarditis, osteomyelitis, pneumonia, and toxic shock syndrome. Antibiotics were first introduced in the 1940s, leading to the belief that bacterial illnesses would be eradicated. However, microorganisms, including S. aureus, began to develop antibiotic resistance from the increased use and abuse of antibiotics. Antibiotic resistance is now one of the most serious threats to global public health. Bacteria like methicillin-resistant Staphylococcus aureus (MRSA) remain a ma...
Source: Frontiers in cellular and infection microbiology - June 17, 2022 Category: Microbiology Source Type: research

Hemodialysis Patient with Streptococcal Toxic Shock Syndrome and Penile Necrosis: A Case Report
Intern Med. 2022 May 31. doi: 10.2169/internalmedicine.9467-22. Online ahead of print.ABSTRACTA 72-year-old man on hemodialysis due to diabetic nephropathy presented with a fever and penile pain. Although his physical examination was unremarkable, his general condition deteriorated. Penile necrosis was observed by evening on the same day of presentation, and the patient died the next morning. Blood cultures revealed the presence of Group G Streptococcus, leading to a diagnosis of streptococcal toxic shock syndrome (STSS). Autopsy suggested penile necrosis due to septic shock. STSS in hemodialysis patients with vascular cal...
Source: Internal Medicine - June 1, 2022 Category: Internal Medicine Authors: Kunihiro Nakai Yu Mihara Hiroshi Kado Yohei Hosokawa Tsuguru Hatta Source Type: research

Livestock-associated methicillin-resistant Staphylococcus aureus in Czech retailed ready-to-eat meat products
This study was aimed on the detection of methicillin resistant Staphylococcus aureus (MRSA) in different categories of retailed ready-to-eat (RTE) meat products from the Czech producers and determination of their genetic properties, antimicrobial resistance and virulence. In RTE meat products, 2% (4/181) of examined samples were MRSA positive. MRSA strains were detected only in durable fermented meat products made exclusively from pork meat. Detection of livestock-associated MRSA (LA-MRSA) clonal lineages (ST398 and ST4999), SCCmec cassette type V and tetracycline resistance indicate a source of contamination from raw pork...
Source: International Journal of Food Microbiology - May 23, 2022 Category: Food Science Authors: Tereza Gelb íčová Krist ýna Brodíková Ren áta Karpíšková Source Type: research

Livestock-associated methicillin-resistant Staphylococcus aureus in Czech retailed ready-to-eat meat products
This study was aimed on the detection of methicillin resistant Staphylococcus aureus (MRSA) in different categories of retailed ready-to-eat (RTE) meat products from the Czech producers and determination of their genetic properties, antimicrobial resistance and virulence. In RTE meat products, 2% (4/181) of examined samples were MRSA positive. MRSA strains were detected only in durable fermented meat products made exclusively from pork meat. Detection of livestock-associated MRSA (LA-MRSA) clonal lineages (ST398 and ST4999), SCCmec cassette type V and tetracycline resistance indicate a source of contamination from raw pork...
Source: International Journal of Food Microbiology - May 23, 2022 Category: Food Science Authors: Tereza Gelb íčová Krist ýna Brodíková Ren áta Karpíšková Source Type: research

Molecules, Vol. 27, Pages 3249: Microarray Analysis of the Genomic Effect of Eugenol on Methicillin-Resistant Staphylococcus aureus
This study enables us to examine complete global transcriptomic responses in MRSA when challenged with eugenol. It reveals novel information with the potential to further benefit the exploratory quest for novel targets against this pathogen, with a view to the development of efficacious antimicrobial agents for the treatment of associated infections. (Source: Molecules)
Source: Molecules - May 19, 2022 Category: Chemistry Authors: Ayuba Sunday Buru Vasantha Kumari Neela Kavitha Mohandas Mallikarjuna Rao Pichika Tags: Article Source Type: research