Methicillin-Resistant < em > Staphylococcus aureus < /em > : Docking-Based Virtual Screening and Molecular Dynamics Simulations to Identify Potential Penicillin-Binding Protein 2a Inhibitors from Natural Flavonoids
This study suggests that kaempferol 3-rutinoside-7-sophoroside and rutin may be considered as drug candidates for therapeutic aims in several human infections associated with MRSA. Nevertheless, in vitro and in vivo confirmations are warranted.PMID:35571353 | PMC:PMC9095385 | DOI:10.1155/2022/9130700 (Source: International Journal of Microbiology)
Source: International Journal of Microbiology - May 16, 2022 Category: Microbiology Authors: Motahareh Masumi Fatemeh Noormohammadi Fatemeh Kianisaba Fatemeh Nouri Mohammad Taheri Amir Taherkhani Source Type: research
Kawasaki disease malingering as juvenile dermatomyositis: case-based review
We report a 10-year-old boy who presented with fever, rash and proximal muscle and pharyngeal weakness. A clinical possibility of toxic shock syndrome or juvenile dermatomyositis was initially considered. However, he continued to have fever and developed periungual peeling of skin in fingers. Hence, a possibility of KD with myositis was considered. He showed prompt response to intravenous immunoglobulin and methylprednisolone. We also provide a review of similarly reported cases of KD myositis. It is important for clinicians to be aware of this atypical clinical presentation to avoid delays in diagnosis and treatment of KD...
Source: Rheumatology International - April 26, 2022 Category: Rheumatology Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: cmaj)
Source: cmaj - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: cmaj)
Source: cmaj - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: cmaj)
Source: cmaj - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: cmaj)
Source: cmaj - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: Canadian Medical Association Journal)
Source: Canadian Medical Association Journal - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Menstrual toxic shock syndrome
CMAJ. 2022 Apr 19;194(15):E555. doi: 10.1503/cmaj.211284.NO ABSTRACTPMID:35440505 | DOI:10.1503/cmaj.211284 (Source: cmaj)
Source: cmaj - April 20, 2022 Category: General Medicine Authors: Takuya Seike Taro Kanaya Naoki Oishi Source Type: research
Toxic shock syndrome: diagnosis and management
Staphylococcal and streptococcal toxic shock syndrome (TSS) is a type of shock that is mediated by superantigens. It is associated with significant morbidity and mortality. Early recognition of this disease is important because the clinical course is fulminant and the outcome depends on the prompt institution of therapy. Management of a child with TSS includes hemodynamic stabilization and appropriate antimicrobial therapy to eradicate the bacteria. The use of immunoglobulin is advised to block the superantigens. (Source: Paediatrics and Child Health)
Source: Paediatrics and Child Health - April 15, 2022 Category: Pediatrics Authors: Catarina Silvestre, Harish Vyas Tags: Occasional review Source Type: research
