Surveillance of noninvasive group A Streptococcus infections in French ambulatory pediatrics before and during the COVID-19 pandemic: a prospective multicenter study from 2018-2022
Group A Streptococcus (GAS) can cause a wider variety of diseases than any other bacterial species, ranging from mild throat and skin infections to uncommon but life-threatening invasive diseases such as streptococcal toxic shock syndrome, necrotizing fasciitis, or bacteremia [1,2]. The most common GAS infection in ambulatory pediatrics is tonsillopharyngitis (i.e., “strep throat”) [2]. In many countries, the diagnosis of GAS tonsillopharyngitis has been facilitated with the use of rapid antigen detection tests (RADTs) [3]. (Source: International Journal of Infectious Diseases)
Source: International Journal of Infectious Diseases - June 5, 2023 Category: Infectious Diseases Authors: J érémie F. Cohen, Alexis Rybak, Andreas Werner, Fabienne Kochert, Fabienne Cahn-Sellem, Nathalie Gelbert, François Vié Le Sage, Christophe Batard, Stéphane Béchet, Hippolyte Corbaux, Bruno Frandji, Corinne Levy, Robert Cohen Source Type: research

Methods to Analyze the Contribution of Complement Evasion Factor (CEF) to Streptococcus pyogenes Virulence
Methods Mol Biol. 2023;2674:119-129. doi: 10.1007/978-1-0716-3243-7_8.ABSTRACTGroup A Streptococcus (GAS, Streptococcus pyogenes) is an exclusively human pathogen that causes a range of diseases, including pharyngitis, tonsillitis, impetigo, erysipelas, necrotizing fasciitis, and toxic shock syndrome. Post-streptococcal sequelae include acute rheumatic fever and rheumatic heart disease. The bacterium produces a large arsenal of virulence factors that contribute to host tissue adhesion/colonization, bacterial spread, and host immune evasion. Immune evasion factors include proteins that interfere with complement, a system of...
Source: Mol Biol Cell - May 31, 2023 Category: Molecular Biology Authors: Haniyeh Aghababa Jacelyn M S Loh Thomas Proft Source Type: research

Rhinologist Use of Antibiotics With Nasal Packing for Epistaxis
CONCLUSIONS: Antibiotic use in patients with epistaxis controlled with nondissolvable packing is common. Treatment patterns are influenced by geography, years in practice, and practice type.LEVEL OF EVIDENCE: 4.PMID:37194285 | DOI:10.1177/19458924231176394 (Source: American Journal of Rhinology and Allergy)
Source: American Journal of Rhinology and Allergy - May 17, 2023 Category: ENT & OMF Authors: Jonathan Ross Mallen Davis M Aasen Jackson Ross Vuncannon Chia-Ling Kuo Jinjian Mu Belachew Tessema Seth M Brown Source Type: research

Staphylococcal toxic shock syndrome
AbstractToxic Shock Syndrome (TSS) is a severe acute disease characterized by high fever, hypotension, rash, multiple organ dysfunction and desquamation during convalescence. TSS is caused by toxin-producing strains ofStaphylococcus aureus or  Streptococcus pyogenes. TSS remains a rare but severe disease. Early diagnosis is important because specific treatments with antitoxin effects must be started as soon as possible.  This manuscript presents a set of images that illustrate the main findings in the peripheral blood film of a patient with TSS. (Source: Journal of Hematopathology)
Source: Journal of Hematopathology - May 11, 2023 Category: Pathology Source Type: research

Paediatric inflammatory multisystem syndrome temporally associated with SARS-CoV-2 (PIMS-TS): what does the future hold?
We read with great interest the recent article by Pouletty et al,1 a multicentre cohort from Paris, which reported an increased incidence of Kawasaki disease (KD) like presentation in association with severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) infection (Kawa-COVID-19) in children. It is considered as a part of (Paediatric inflammatory multisystem syndrome temporally associated (PIMS-TS) with SARS-CoV-2). The varied manifestations of PIMS-TS include KD-like illness, toxic shock syndrome and multisystem failure.2–4 There is a significant difference in epidemiology and diagnostic criteria used to iden...
Source: Annals of the Rheumatic Diseases - April 12, 2023 Category: Rheumatology Authors: Sudhakar, M., Vignesh, P. Tags: ARD, COVID-19 Correspondence Source Type: research

Toxic Shock Syndrome with Breast Abscess in a Breast-Feeding Woman
(Source: Journal of General Internal Medicine)
Source: Journal of General Internal Medicine - March 31, 2023 Category: Internal Medicine Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research

Comparison of Characteristics and Outcomes of Multisystem Inflammatory Syndrome, Kawasaki Disease and Toxic Shock Syndrome in Children
Conclusions: This research shows that MIS-C, KD and TSS have several clinical similarities and additional investigations are required for reaching final diagnosis. All the patients with suspected MIS-C diagnosis should be examined for possible cardiovascular involvement including cardiac biomarkers, ECG and echocardiography.PMID:36984627 | PMC:PMC10056689 | DOI:10.3390/medicina59030626 (Source: Medicina (Kaunas))
Source: Medicina (Kaunas) - March 29, 2023 Category: Universities & Medical Training Authors: Lizete Klavina Liene Smane Anda Kivite-Urtane Lauma Vasilevska Zane Davidsone Emils Smitins Dace Gardovska Inguna Lubaua Ieva Roge Zanda Pucuka Anija Meiere Jana Pavare Source Type: research