Perspectives from Adults with Tourette Syndrome on Research Priorities and Registry Development: A Focus Group Study
(Source: Neuropsychiatric Disease and Treatment)
Source: Neuropsychiatric Disease and Treatment - February 9, 2024 Category: Psychiatry Tags: Neuropsychiatric Disease and Treatment Source Type: research

Thalamic deep brain stimulation for tourette syndrome increases cortical beta activity
Deep brain stimulation (DBS) of the thalamus can effectively reduce tics in severely affected patients with Tourette syndrome (TS). Its effect on cortical oscillatory activity is currently unknown. (Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation)
Source: BRAIN STIMULATION: Basic, Translational, and Clinical Research in Neuromodulation - February 8, 2024 Category: Neurology Authors: Thomas Sch üller, Daniel Huys, Sina Kohl, Veerle Visser-Vandewalle, Till A. Dembek, Jens Kuhn, Juan Carlos Baldermann, Ezra E. Smith Source Type: research

Biomarkers and Tourette syndrome: a systematic review and meta-analysis
ConclusionIn this study, we present empirical evidence substantiating the link between several peripheral biomarkers and the early diagnosis of TS. Larger and more standardized studies are necessary to replicate the observed results, elucidate the specificity of the biomarkers for TS, and evaluate their precision for use in clinical settings. (Source: Frontiers in Neurology)
Source: Frontiers in Neurology - February 7, 2024 Category: Neurology Source Type: research

The Association of Quality of Life with Psychosocial Factors in Adolescents with Tourette Syndrome
Child Psychiatry Hum Dev. 2024 Feb 4. doi: 10.1007/s10578-023-01656-0. Online ahead of print.ABSTRACTIndividuals with Tourette syndrome (TS) have poorer quality of life (QoL) than their peers, yet factors contributing to poor QoL in this population remain unclear. Research to date has predominantly focused on the impact of tics and psychiatric symptoms on QoL in TS samples. The aim of this cross-sectional, multi-informant study was to identify psychosocial variables that may impact adolescent QoL in TS. Thirty-eight adolescents aged 13 to 17 with TS and 28 age-matched controls participated with a caregiver. No group differ...
Source: Child Psychiatry and Human Development - February 4, 2024 Category: Child Development Authors: Kelly H Watson Michelle Eckland Jessica M Schwartzman Andrew Molnar Whitney Boon Matthew Hiller Seth Scholer Rachel Mace Alice Rothman Daniel O Claassen Heather R Riordan David A Isaacs Source Type: research

The Effects of a Laparoscopy by Single-Port Endoscopic Access in Benign Adnexal Surgery: A Randomized Controlled Trial
To evaluate whether Laparoendoscopic Single-Site Surgery (LESS) offers advantages over conventional laparoscopy (CL) in benign adnexal surgery (Source: The Journal of Minimally Invasive Gynecology)
Source: The Journal of Minimally Invasive Gynecology - February 1, 2024 Category: OBGYN Authors: Andy SCHMITT, Patrice CROCHET, Audrey PIVANO, Claire TOURETTE, Cindy FAUST, Karine BAUMSTARCK, Aubert AGOSTINI Tags: Original Article Source Type: research

Altered dynamic functional and effective connectivity in drug-naive children with Tourette syndrome
Translational Psychiatry, Published online: 22 January 2024; doi:10.1038/s41398-024-02779-1Altered dynamic functional and effective connectivity in drug-naive children with Tourette syndrome (Source: Translational Psychiatry)
Source: Translational Psychiatry - January 22, 2024 Category: Psychiatry Authors: Lekai Luo Yi Liao Fenglin Jia Gang Ning Jing Liu Xuesheng Li Xijian Chen Xinmao Ma Xuejia He Chuan Fu Xiaotang Cai Haibo Qu Source Type: research

Co-morbid tics and stereotypies: a systematic literature review
DiscussionTics and stereotypies can often develop in co-morbidity. The association of tics and stereotypies in the same patient has practical implications, in consideration of the different treatment approaches. Future research should focus on the assessment and management of both conditions, particularly in special populations (e.g. patients with pervasive developmental disorders). (Source: Neurological Sciences)
Source: Neurological Sciences - January 18, 2024 Category: Neurology Source Type: research

Relationship between transcranial magnetic stimulation markers of motor control and clinical recovery in obsessive compulsive disorder/Gilles de la Tourette syndrome: a proof of concept case study
ConclusionThis study highlights the importance of better understanding motor inhibitory mechanisms in neurodevelopmental disorders and suggests a biofeedback approach as a potential novel treatment. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - January 17, 2024 Category: Psychiatry Source Type: research

Parent-Report Sleep Disturbances and Everyday Executive Functioning Difficulties in Children with Tourette Syndrome
. (Source: Developmental Neuropsychology)
Source: Developmental Neuropsychology - January 15, 2024 Category: Neurology Authors: Lisa KeenanJessica BramhamMichelle DownesSchool of Psychology, University College Dublin, Dublin, Ireland Source Type: research

What distinguishes patients with mass social media-induced illness presenting with Tourette-like behavior from those with Tourette syndrome? Results of a prospective cohort study
AbstractSince 2019, a global increase in patients presenting with functional Tourette-like behaviors (FTB) has been observed. This has been related to the exposure of tic-related content in social media, although other factors seem to further fuel this phenomenon. Recently, we, therefore, proposed the term mass social media-induced illness (MSMI) as, in our opinion, this phenomenon constitutes a new type of mass sociogenic illness (MSI) that is in contrast to all recent outbreaks spread solely via social media. In accordance with this hypothesis, we were able to identify the host of the German YouTube channel"Gewitter...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 13, 2024 Category: Neuroscience Source Type: research

Micropopulation mapping of the mouse parafascicular nucleus connections reveals diverse input –output motifs
DiscussionOur data thus indicate that the mouse Pf consists of several neurochemically and connectively distinct domains whose global organization bears a marked similarity to that described in the primate CM-Pf complex. (Source: Frontiers in Neuroanatomy)
Source: Frontiers in Neuroanatomy - January 8, 2024 Category: Neurology Source Type: research

Mapping Gilles de la Tourette syndrome through the distress and relief associated with tic-related behaviors: an fMRI study
Translational Psychiatry, Published online: 08 January 2024; doi:10.1038/s41398-023-02711-zMapping Gilles de la Tourette syndrome through the distress and relief associated with tic-related behaviors: an fMRI study (Source: Translational Psychiatry)
Source: Translational Psychiatry - January 8, 2024 Category: Psychiatry Authors: Laura Zapparoli Francantonio Devoto Marika Mariano Silvia Seghezzi Domenico Servello Mauro Porta Eraldo Paulesu Source Type: research

Networkmodulation through deep brain stimulation
CONCLUSION: DBS is a safe technique with a proven effect on more than 200,000 patients with movement disorders. Trials into the application of DBS for the most important psychiatric and cognitive indications are important.PMID:38174396 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - January 4, 2024 Category: Psychiatry Authors: V Visser-Vandewalle Source Type: research

The Severity and Neural Correlates of Premonitory Urge in Tourette Syndrome: A Systematic Review and Meta-Analysis
CONCLUSIONS: Our meta-analysis confirmed the positive relationship between the severity of tics and PU and identified age as a significant factor influencing PU. The neural mechanisms underlying PU remain largely unknown, but evidence suggests that the insula, PFC, ACC, and SMA are related regions.PMID:38176915 | DOI:10.31083/j.jin2206159 (Source: Journal of Integrative Neuroscience)
Source: Journal of Integrative Neuroscience - January 4, 2024 Category: Neuroscience Authors: Yanlin Li Liping Yu Hua Zhang Xianbian Wang Yonghua Cui Ying Li Source Type: research

Networkmodulation through deep brain stimulation
CONCLUSION: DBS is a safe technique with a proven effect on more than 200,000 patients with movement disorders. Trials into the application of DBS for the most important psychiatric and cognitive indications are important.PMID:38174396 (Source: Tijdschrift voor Psychiatrie)
Source: Tijdschrift voor Psychiatrie - January 4, 2024 Category: Psychiatry Authors: V Visser-Vandewalle Source Type: research