Tourette Syndrome and Obsessive-Compulsive Disorder: A Comprehensive Review of Structural Alterations and Neurological Mechanisms
Behav Brain Res. 2023 Jul 29:114606. doi: 10.1016/j.bbr.2023.114606. Online ahead of print.ABSTRACTCurrently, it is possible to study the pathogenesis of Tourette's syndrome (TS) in more detail, due to more advanced methods of neuroimaging. However, medical and surgical treatment options are limited by a lack of understanding of the nature of the disorder and its relationship to some psychiatric disorders, the most common of which is obsessive-compulsive disorder (OCD). It is believed that the origin of chronic tic disorders is based on an imbalance of excitatory and inhibitory influences in the Cortico-Striato-Thalamo-Cor...
Source: Behavioural Brain Research - July 31, 2023 Category: Neurology Authors: Anna D Shitova Tatyana S Zharikova Olga N Kovaleva Anastasia M Luchina Arthur S Aktemirov Anna V Olsufieva Mikhail Y Sinelnikov Andr é Pontes-Silva Yury O Zharikov Source Type: research
Tourette Syndrome and Obsessive-Compulsive Disorder: A Comprehensive Review of Structural Alterations and Neurological Mechanisms
Behav Brain Res. 2023 Jul 29:114606. doi: 10.1016/j.bbr.2023.114606. Online ahead of print.ABSTRACTCurrently, it is possible to study the pathogenesis of Tourette's syndrome (TS) in more detail, due to more advanced methods of neuroimaging. However, medical and surgical treatment options are limited by a lack of understanding of the nature of the disorder and its relationship to some psychiatric disorders, the most common of which is obsessive-compulsive disorder (OCD). It is believed that the origin of chronic tic disorders is based on an imbalance of excitatory and inhibitory influences in the Cortico-Striato-Thalamo-Cor...
Source: Brain Research - July 31, 2023 Category: Neurology Authors: Anna D Shitova Tatyana S Zharikova Olga N Kovaleva Anastasia M Luchina Arthur S Aktemirov Anna V Olsufieva Mikhail Y Sinelnikov Andr é Pontes-Silva Yury O Zharikov Source Type: research
Tourette Syndrome and Obsessive-Compulsive Disorder: A Comprehensive Review of Structural Alterations and Neurological Mechanisms
Behav Brain Res. 2023 Jul 29:114606. doi: 10.1016/j.bbr.2023.114606. Online ahead of print.ABSTRACTCurrently, it is possible to study the pathogenesis of Tourette's syndrome (TS) in more detail, due to more advanced methods of neuroimaging. However, medical and surgical treatment options are limited by a lack of understanding of the nature of the disorder and its relationship to some psychiatric disorders, the most common of which is obsessive-compulsive disorder (OCD). It is believed that the origin of chronic tic disorders is based on an imbalance of excitatory and inhibitory influences in the Cortico-Striato-Thalamo-Cor...
Source: Behavioural Brain Research - July 31, 2023 Category: Neurology Authors: Anna D Shitova Tatyana S Zharikova Olga N Kovaleva Anastasia M Luchina Arthur S Aktemirov Anna V Olsufieva Mikhail Y Sinelnikov Andr é Pontes-Silva Yury O Zharikov Source Type: research
Functional connectivity during tic suppression predicts reductions in vocal tics following behavior therapy in children with Tourette syndrome
CONCLUSIONS: This study revealed that functional connectivity during tic suppression at baseline predicted reduction in vocal tic severity. These results suggest probable overlap between the mechanisms of voluntary tic suppression and those of behavior therapy for tics.PMID:37485677 | DOI:10.1017/S0033291723001940 (Source: Psychological Medicine)
Source: Psychological Medicine - July 24, 2023 Category: Psychiatry Authors: Simon Morand-Beaulieu Michael J Crowley Heidi Grantz James F Leckman Denis G Sukhodolsky Source Type: research
Functional connectivity during tic suppression predicts reductions in vocal tics following behavior therapy in children with Tourette syndrome
CONCLUSIONS: This study revealed that functional connectivity during tic suppression at baseline predicted reduction in vocal tic severity. These results suggest probable overlap between the mechanisms of voluntary tic suppression and those of behavior therapy for tics.PMID:37485677 | DOI:10.1017/S0033291723001940 (Source: Psychological Medicine)
Source: Psychological Medicine - July 24, 2023 Category: Psychiatry Authors: Simon Morand-Beaulieu Michael J Crowley Heidi Grantz James F Leckman Denis G Sukhodolsky Source Type: research
Compulsive sexual behavior and paraphilic interests in adults with chronic tic disorders and Tourette syndrome: a survey-based study
International Journal of Impotence Research, Published online: 19 July 2023; doi:10.1038/s41443-023-00729-xCompulsive sexual behavior and paraphilic interests in adults with chronic tic disorders and Tourette syndrome: a survey-based study (Source: International Journal of Impotence Research)
Source: International Journal of Impotence Research - July 19, 2023 Category: Urology & Nephrology Authors: Lille Kurvits Safiye Tozdan Tina Mainka Alexander M ünchau Kirsten R. M üller-Vahl Andrea E. Cavanna Peer Briken Christos Ganos Source Type: research
Direct additive genetics and maternal effect contribute to the risk of Tourette disorder
Conclusions
Our results demonstrate genetic maternal effect contributes to the risk of CTD. Failure to account for maternal effect results in an incomplete understanding of the genetic risk architecture of CTD, as the risk for CTD is impacted by maternal effect which is above and beyond the risk from transmitted genetic effect. (Source: Journal of Neurology, Neurosurgery and Psychiatry)
Source: Journal of Neurology, Neurosurgery and Psychiatry - July 13, 2023 Category: Neurosurgery Authors: Mahjani, B., Klei, L., Buxbaum Grice, A. S., Larsson, H., Hultman, C. M., Sandin, S., Devlin, B., Buxbaum, J. D., Grice, D. E. Tags: Neuropsychiatry Source Type: research
Mechanisms of cannabinoid tolerance
Biochem Pharmacol. 2023 Jun 20:115665. doi: 10.1016/j.bcp.2023.115665. Online ahead of print.ABSTRACTCannabis has been used recreationally and medically for centuries, yet research into understanding the mechanisms of its therapeutic effects has only recently garnered more attention. There is evidence to support the use of cannabinoids for the treatment of chronic pain, muscle spasticity, nausea and vomiting due to chemotherapy, improving weight gain in HIV-related cachexia, emesis, sleep disorders, managing symptoms in Tourette syndrome, and patient-reported muscle spasticity from multiple sclerosis. However, tolerance th...
Source: Biochemical Pharmacology - June 22, 2023 Category: Drugs & Pharmacology Authors: Mary K Piscura Angela N Henderson-Redmond Robert C Barnes Swarup Mitra Jos ée Guindon Daniel J Morgan Source Type: research
Mechanisms of cannabinoid tolerance
Biochem Pharmacol. 2023 Jun 20:115665. doi: 10.1016/j.bcp.2023.115665. Online ahead of print.ABSTRACTCannabis has been used recreationally and medically for centuries, yet research into understanding the mechanisms of its therapeutic effects has only recently garnered more attention. There is evidence to support the use of cannabinoids for the treatment of chronic pain, muscle spasticity, nausea and vomiting due to chemotherapy, improving weight gain in HIV-related cachexia, emesis, sleep disorders, managing symptoms in Tourette syndrome, and patient-reported muscle spasticity from multiple sclerosis. However, tolerance th...
Source: Biochemical Pharmacology - June 22, 2023 Category: Drugs & Pharmacology Authors: Mary K Piscura Angela N Henderson-Redmond Robert C Barnes Swarup Mitra Jos ée Guindon Daniel J Morgan Source Type: research
Mechanisms of cannabinoid tolerance
Biochem Pharmacol. 2023 Jun 20:115665. doi: 10.1016/j.bcp.2023.115665. Online ahead of print.ABSTRACTCannabis has been used recreationally and medically for centuries, yet research into understanding the mechanisms of its therapeutic effects has only recently garnered more attention. There is evidence to support the use of cannabinoids for the treatment of chronic pain, muscle spasticity, nausea and vomiting due to chemotherapy, improving weight gain in HIV-related cachexia, emesis, sleep disorders, managing symptoms in Tourette syndrome, and patient-reported muscle spasticity from multiple sclerosis. However, tolerance th...
Source: Biochemical Pharmacology - June 22, 2023 Category: Drugs & Pharmacology Authors: Mary K Piscura Angela N Henderson-Redmond Robert C Barnes Swarup Mitra Jos ée Guindon Daniel J Morgan Source Type: research
Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research
Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research
Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research
Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research
Investigating the effects and side effects of two antipsychotic drugs in the treatment of children and adolescents with Tourette syndrome: a semi-experimental research
CONCLUSION: According to the results, the two medicines, Aripiprazole and Risperidone, effectively improved the symptoms of Tourette's disorder and its overall severity. However, there were no significant statistical differences between them. Furthermore, in terms of the medical side effects, the statistical comparison between the two medicines was impossible due to the small number of complications.PMID:37303178 | DOI:10.2174/1570163820666230609095720 (Source: Current Drug Discovery Technologies)
Source: Current Drug Discovery Technologies - June 12, 2023 Category: Drugs & Pharmacology Authors: Atefeh Soltanifar Raheleh Lashkarnevis Maliheh Ziaee Fatemeh Moharari Roya Samadi Azadeh Soltanifar Maedeh Kamrani Source Type: research
