Editorial: Recent advances in understanding Tourette syndrome, tic disorders and functional tics
(Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - March 30, 2023 Category: Psychiatry Source Type: research
Differences in Tic Severity Among Adolescent Girls and Boys with Tourette Syndrome During the Pandemic
Conclusion These findings provide evidence that, regarding tic severity assessed with YGTSS, the experiences of adolescent girls and boys with TS have differed during the pandemic. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | Full text (Source: Neuropediatrics)
Source: Neuropediatrics - March 24, 2023 Category: Neurology Authors: Larsh, Travis R. Wu, Steve W. Huddleston, David A. Lipps, Tara D. Gilbert, Donald L. Tags: Short Communications Source Type: research
Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders
In conclusion, taken together, the current findings pave that way towards novel and promising domains to explore the pathophysiology of OCD and related disorders, as well towards the development of innovative therapeutic strategy beyond current pharmacological paradigms.PMID:36949315 | DOI:10.1007/978-981-19-7376-5_13 (Source: Adv Data)
Source: Adv Data - March 23, 2023 Category: Epidemiology Authors: Donatella Marazziti Stefania Palermo Alessandro Arone Lucia Massa Elisabetta Parra Marly Simoncini Lucia Martucci Maria Francesca Beatino Andrea Pozza Source Type: research
Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders
In conclusion, taken together, the current findings pave that way towards novel and promising domains to explore the pathophysiology of OCD and related disorders, as well towards the development of innovative therapeutic strategy beyond current pharmacological paradigms.PMID:36949315 | DOI:10.1007/978-981-19-7376-5_13 (Source: Advances in Experimental Medicine and Biology)
Source: Advances in Experimental Medicine and Biology - March 23, 2023 Category: Research Authors: Donatella Marazziti Stefania Palermo Alessandro Arone Lucia Massa Elisabetta Parra Marly Simoncini Lucia Martucci Maria Francesca Beatino Andrea Pozza Source Type: research
Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders
In conclusion, taken together, the current findings pave that way towards novel and promising domains to explore the pathophysiology of OCD and related disorders, as well towards the development of innovative therapeutic strategy beyond current pharmacological paradigms.PMID:36949315 | DOI:10.1007/978-981-19-7376-5_13 (Source: Adv Data)
Source: Adv Data - March 23, 2023 Category: Epidemiology Authors: Donatella Marazziti Stefania Palermo Alessandro Arone Lucia Massa Elisabetta Parra Marly Simoncini Lucia Martucci Maria Francesca Beatino Andrea Pozza Source Type: research
Obsessive-Compulsive Disorder, PANDAS, and Tourette Syndrome: Immuno-inflammatory Disorders
In conclusion, taken together, the current findings pave that way towards novel and promising domains to explore the pathophysiology of OCD and related disorders, as well towards the development of innovative therapeutic strategy beyond current pharmacological paradigms.PMID:36949315 | DOI:10.1007/978-981-19-7376-5_13 (Source: Advances in Experimental Medicine and Biology)
Source: Advances in Experimental Medicine and Biology - March 23, 2023 Category: Research Authors: Donatella Marazziti Stefania Palermo Alessandro Arone Lucia Massa Elisabetta Parra Marly Simoncini Lucia Martucci Maria Francesca Beatino Andrea Pozza Source Type: research
Pre-movement gating of somatosensory evoked potentials in tourette syndrome
Tourette syndrome (TS) is a neurobehavioral disorder characterized by motor and vocal tics. Simple tics are purposeless involuntary movements that spontaneously resolve during middle adolescence. Complex tics appear to be semi-voluntary movements that may become intractable when associated with obsessive –compulsive disorder (OCD). Sensory tics or urges preceded by tics suggest sensorimotor processing impairment in TS. We aimed to clarify its pathophysiology by exploring the pre-movement gating (attenuation) of somatosensory evoked potentials (SEPs). (Source: Brain and Development)
Source: Brain and Development - March 4, 2023 Category: Neurology Authors: Kazue Kimura, Nagako Murase, Yuri Nagao, Maki Nozaki, Michio Fukumizu, Yosuke Kita, Masaharu Hayashi, Kyoko Hoshino Tags: Original article Source Type: research
Efficacy of cannabinoids in neurodevelopmental and neuropsychiatric disorders among children and adolescents: a systematic review
AbstractA better understanding of the endocannabinoid system and a relaxation in regulatory control of cannabis globally has increased interest in the medicinal use of cannabinoid-based products (CBP). We provide a systematic review of the rationale and current clinical trial evidence for CBP in the treatment of neuropsychiatric and neurodevelopmental disorders in children and adolescents. A systematic search of MEDLINE, Embase, PsycINFO, and the Cochrane Central Register of Trials was performed to identify articles published after 1980 about CBP for medical purposes in individuals aged 18 years or younger with selected...
Source: European Child and Adolescent Psychiatry - March 3, 2023 Category: Psychiatry Source Type: research
Dual-Target Deep Brain Stimulation for Obsessive-Compulsive Disorder and Tourette Syndrome
Deep brain stimulation (DBS) has been used effectively for both treatment-resistant obsessive-compulsive disorder (OCD) and Tourette syndrome (TS) (1,2). While DBS of the anterior limb of the internal capsule is Food and Drug Administration approved for use in OCD under a Humanitarian Device Exemption, DBS for TS is still considered investigational (3,4). Several DBS targets for TS have been studied, most prominently the globus pallidus internus (GPi) and centromedian/parafascicular thalamus, though no single best target has emerged (2,5). (Source: Biological Psychiatry)
Source: Biological Psychiatry - March 1, 2023 Category: Psychiatry Authors: Ricardo A. Najera, Nicole Provenza, Huy Dang, Kalman A. Katlowitz, Alyssa Hertz, Sandesh Reddy, Ben Shofty, Steven T. Bellows, Eric A. Storch, Wayne K. Goodman, Sameer A. Sheth Tags: Correspondence Source Type: research
Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome
Translational Psychiatry, Published online: 23 February 2023; doi:10.1038/s41398-023-02341-5Polygenic risk score-based phenome-wide association study identifies novel associations for Tourette syndrome (Source: Translational Psychiatry)
Source: Translational Psychiatry - February 23, 2023 Category: Psychiatry Authors: Pritesh Jain Tyne Miller-Fleming Apostolia Topaloudi Dongmei Yu Petros Drineas Marianthi Georgitsi Zhiyu Yang Renata Rizzo Kirsten R. M üller-Vahl Zeynep Tumer Nanette Mol Debes Andreas Hartmann Christel Depienne Yulia Worbe Pablo Mir Danielle C. Cath Do Source Type: research
Highlights from the literature
Tourette’s syndrome Tics are common. Usually, the clinician can reassure the family and child and with time, observation and support, the tics go away without intervention. If they become more complex with both motor and vocal components and continue over 12 months, then there is concern of Tourette’s syndrome. What treatment should be offered initially once a diagnosis is made in children and young adults? The guidelines are inconsistent. Farhat et al [The Lancet Child & Adolescent Health 2023;7 (2):112–126. https://doi.org/10.1016/S2352-4642(22)00316-9] have completed a systematic review and metanal...
Source: Archives of Disease in Childhood - February 17, 2023 Category: Pediatrics Tags: Miscellanea Source Type: research
Advances in Tourette ’s syndrome
(Source: Journal of Neurology)
Source: Journal of Neurology - February 17, 2023 Category: Neurology Source Type: research
Genes, Vol. 14, Pages 500: Copy Number Variations in Children with Tourette Syndrome: Systematic Investigation in a Clinical Setting
Renata Rizzo
Tourette syndrome (TS) is a neurodevelopmental disturbance with heterogeneous and not completely known etiology. Clinical and molecular appraisal of affected patients is mandatory for outcome amelioration. The current study aimed to understand the molecular bases underpinning TS in a vast cohort of pediatric patients with TS. Molecular analyses included array-CGH analyses. The primary goal was to define the neurobehavioral phenotype of patients with or without pathogenic copy number variations (CNVs). Moreover, we compared the CNVs with CNVs described in the literature in neuropsychiatric disorders, inclu...
Source: Genes - February 15, 2023 Category: Genetics & Stem Cells Authors: Federica Saia Adriana Prato Lucia Saccuzzo Francesca Madia Rita Barone Marco Fichera Renata Rizzo Tags: Article Source Type: research
