Psychopathological aspects of sexting and IBSA perpetrators: A brief research report
ConclusionsIBSA perpetrators share key factors that could be targeted in forensic and clinical interventions, and that should be taken into account when designing effective offender intervention programs. Intervention programs should focus on anger-management issues that help reduce perpetrators' hostility and anxiety symptoms, and should also be aimed at modifying attitudes that justify perpetration behaviors and contribute to harmful interactions with their friends or to intimate partner violent dynamics. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 29, 2022 Category: Psychiatry Source Type: research

Support staff liaising effectively with professionals for the rational use of psychotropics for behaviours that challenge in adults with intellectual disabilities: Findings from a co-design event
Experience Based Co-Design (EBCD) and co-production are interdisciplinary collaborative approaches to improve health care services by involving all stakeholders. These approaches capture the experiences of all stakeholders who come in contact with services and use experiences as evidence to promote and implement service changes. The use of psychotropic medications for behaviours that challenge (BtC) in people with intellectual disabilities (ID) is a complex issue because of its off-licence use and use in combination with other medications for physical and psychiatric co-morbidities, which leads to overmedication of people ...
Source: Frontiers in Psychiatry - September 29, 2022 Category: Psychiatry Source Type: research

Examination of the importance of anger/irritability and limited prosocial emotion/callous-unemotional traits to understand externalizing symptoms and adjustment problems in adolescence: A 10-year longitudinal study
DiscussionOur results suggest that dysregulation of anger/irritability is a key factor in the prediction of long-term externalizing symptoms and adjustment problems as well as its worsening over time. Possible implications for intervention and prevention are discussed. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 29, 2022 Category: Psychiatry Source Type: research

Intravenous ketamine for depression: A clinical discussion reconsidering best practices in acute hypertension management
Ketamine is a versatile medication with an emerging role for the treatment of numerous psychiatric conditions, including treatment resistant depression. Current psychiatry guidelines for its intravenous administration to treat depression recommend regular blood pressure monitoring and an aggressive approach to potential transient hypertensive episodes induced by ketamine infusions. While this approach is aimed at ensuring patient safety, it should be updated to align with best practice guidelines in the management of hypertension. This review defines and summarizes the currently recommended approach to the hypertensive eme...
Source: Frontiers in Psychiatry - September 29, 2022 Category: Psychiatry Source Type: research

Abnormal degree centrality in first-episode medication-free adolescent depression at rest: A functional magnetic resonance imaging study and support vector machine analysis
ConclusionThese results suggest that whole-brain network centrality abnormalities may be present in many brain regions in adolescent depression patients. Accordingly, these DC maps may hold value as candidate neuroimaging biomarkers capable of differentiating between adolescents who are and are not affected by MDD, although further validation of these results will be critical. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 29, 2022 Category: Psychiatry Source Type: research

Editorial: Novel antipsychotics within and beyond clinical trials: The treatment of overlapping psychiatric disorders with D3-D2 partial agonists
(Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Factors associated with a borderline personality disorder diagnosis in the emergency department
ConclusionThis study found that patients without an established BPD diagnosis who present at the ED are more likely to not be known to the psychiatric care system. This suggests that EDs have a specific role to play in making a diagnosis and the subsequent orientation of care. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Factors that determine mental health professionals ’ decision to support home-based video consultations – A qualitative study
ConclusionPerceived usefulness, patient demands, and close IT support will positively impact the establishment and realization of video consultations whereas high workload and technical problems would hamper it. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Plasma metabolomics of schizophrenia with cognitive impairment: A pilot study
In this study, several differentially expressed metabolites were identified in SCZ with cognitive impairment, providing novel insights into clinical treatment strategies. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Repetitive transcranial magnetic stimulation for insomnia in patients with autism spectrum disorder: Study protocol for a randomized, double-blind, and sham-controlled clinical trial
This study is designed to be a double-blind, randomized, and sham-controlled trial with a target sample size of 30 participants (aged 3–13 years) diagnosed with ASD comorbid with insomnia. The intervention phase will comprise 20 sessions of rTMS or sham rTMS applied over the right dorsolateral prefrontal cortex (DLPFC) within four consecutive weeks. The effect of rTMS on insomnia and other symptoms of ASD will be investigated through home-PSG (two consecutive overnights), sleep diary, CSHQ, CARS, ABC, SRS, RBS-R, and metabolomics analysis at baseline and posttreatment. A follow-up assessment 1 month after the interventio...
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

The interaction of occupational stress, mental health, and cytokine levels on sleep in Xinjiang oil workers: A cross-sectional study
ConclusionOil workers have serious sleep problems, so effective measures should be taken to reduce occupational stress and relieve mental health problems, and cytokine levels can be used as a predictor of sleep disorders. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Characteristics associated with treatment seeking for smoking cessation among heavy-drinking research participants
ConclusionIndividuals who are daily smokers and consume more drinks per drinking day are less likely to belong to the smoking cessationtreatment-seeking group. Targeting heavy drinking smokers, particularly younger individuals, may be necessary to engage this group in smoking cessation efforts and to reduce the burden of disease of nicotine dependence earlier in the lifespan. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Synthesis and pharmacological evaluation of newly detected synthetic cannabinoid receptor agonists AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA, MDMB-4F-BUTINACA and their analogs
Synthetic cannabinoid receptor agonists (SCRAs) continue to make up a significant portion new psychoactive substances (NPS) detected and seized worldwide. Due to their often potent activation of central cannabinoid receptors in vivo, use of SCRAs can result in severe intoxication, in addition to other adverse health effects. Recent detections of AB-4CN-BUTICA, MMB-4CN-BUTINACA, MDMB-4F-BUTICA and MDMB-4F-BUTINACA mark a continuation in the appearance of SCRAs bearing novel tail substituents. The proactive characterization campaign described here has facilitated the detection of several new SCRAs in toxicological case work....
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Safety, effectiveness and tolerability of sublingual ketamine in depression and anxiety: A retrospective study of off-label, at-home use
This study assessed the effectiveness and safety of self-administration of off-label, SL, rapid dissolve ketamine tablets (RDT) at-home for depression and anxiety. Intake scores on the Generalized Anxiety Disorder Screener (GAD-7) and Patient Health Questionnaire (PHQ-9) were compared to scores after treatments of three doses of ketamine RDT, and after six doses of ketamine RDT. After three doses of SL ketamine, 47.6% of patients showed a significant decrease in PHQ-9 scores, and 47.6% of patients showed a significant reduction in GAD-7 scores. Reduction rates were higher in those patients who completed a clinically recomm...
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research

Validation of the Chinese version of the Somatic Symptom Scale-8 in patients from tertiary hospitals in China
ConclusionOur preliminary assessment suggests that the Chinese language version of the SSS-8 has reliability and validity sufficient to warrant testing further in research and clinical settings. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - September 28, 2022 Category: Psychiatry Source Type: research