Empathy and Theory of Mind in Multiple Sclerosis: A Meta-Analysis
Multiple sclerosis (MS) is an immune-mediated demyelinating disease of the central nervous system. Studies have shown that MS disrupts several social cognitive abilities [including empathy and theory of mind (ToM)]. Overall ToM deficits in MS are well documented, but how the specific ToM subcomponents and empathic capacity are affected remains unclear. For this meta-analysis, we searched PubMed, Web of Science, and Embase from inception to July 2020. Effect sizes were calculated using Hedges g with a random-effects model. Thirty-three studies were included. Relative to healthy controls (HCs), patients with MS were moderate...
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Case Report: The Sexual Experiences of Forensic Mental Health Patients
The recovery-based approach to forensic mental health rehabilitation is to support the patient to achieve a fulfilling life—a principle which should include achieving a fulfilling sexual life. This paper presents four vignettes from forensic mental health patients. The four cases demonstrate the omission, avoidance and then judgement by forensic mental health clinicians around the intimate and sensitive, yet important domain of the patient's sexual life. The cases illustrate that gap in the clinical domain and demonstrate the requirement for forensic mental health clinicians to have a greater awareness, acknowledgmen...
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Mental Symptoms and Stress of Hospitalized Schizophrenia Patients With 2019 Novel Coronavirus Disease: An Observation Study
This study took hospitalized schizophrenia patients with COVID-19 as the research subjects and observed the changes in psychopathology and stress of patients with COVID-19 and the accompanying social isolation.Methods: To sort and isolate potential COVID-19-infected patients, an isolated ward was set up from January 30, 2020, to March 30, 2020. Schizophrenia patients with COVID-19 were referred to this ward, and long-term hospitalized cases were included in this study. The Positive and Negative Syndrome Scale and Perceived Stress Scale were used to evaluate the severity of mental symptoms and psychological stress in the ea...
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

The Pharmacodynamics of Antipsychotic Drugs in Women and Men
Conclusion: On average, women's psychotic symptoms respond to antipsychotic drugs at doses lower than men's. This means that many women may be de facto overdosed and, thus, experience unnecessary adverse effects. That being said, factors such as genetics and age probably determine drug response and tolerability to a greater degree than do biological sex or gender social roles. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

The Relationship Between Different Aspects of Theory of Mind and Symptom Clusters in Psychotic Disorders: Deconstructing Theory of Mind Into Cognitive, Affective, and Hyper Theory of Mind
Conclusions: Our findings suggest that deficits in ToM subtypes might not be directly related to delusions and positive symptoms and are in line with more recently developed cognitive models of delusions. In addition, our results support the well-established finding of associations between ToM alterations and negative or disorganized symptoms. Our results shed light on the role of different dimensions of ToM in specific symptoms of psychosis. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Alexithymia in Patients With Substance Use Disorders and Its Relationship With Psychiatric Comorbidities and Health-Related Quality of Life
Conclusions: SUD patients with higher alexithymia levels have more frequently psychiatric comorbidities, present specific psychological features, and have worse HRQoL. Hence, it is important to evaluate these factors and offer more accurate psychotherapeutic approaches for this patient population. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Music Therapy for Children With Autistic Spectrum Disorder and/or Other Neurodevelopmental Disorders: A Systematic Review
Discussion: Improvisational music therapy in children with NDDs appears relevant for individuals with both ASD and ID. More research should be encouraged to explore whether oral and written language skills may improve after educational music therapy, as preliminary data are encouraging. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

The Mediating Roles of Emotional Regulation on Negative Emotion and Internet Addiction Among Chinese Adolescents From a Development Perspective
This study has examined 716 Chinese adolescents, 341 were males (47.6%), aged 13 to 18(Mean = 14.58, SD = 1.50), using a cross-sectional survey involving Young's Diagnostic Questionnaire for Internet Addiction, the nine-item Patient Health Questionnaire (PHQ-9), the seven-item Generalized Anxiety (GAD-7) scale, and the Emotion Regulation Questionnaire (ERQ). Correlation analysis, multiple-group analysis and structural equation modeling were carried out in SPSS Statistics version 23 (IBM, Armonk, NY) and AMOS version 21. Cognitive reappraisal had a significantly negative direct effect on Internet addiction (β = −0.118, p
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Aging in Context: Incorporating Everyday Experiences Into the Study of Subjective Age
The age that a person feels is a strong predictor of their well-being and long-term health, beyond chronological age, showing that people have a self-awareness that provides insight into their aging process. It appears this insight has broad implications for a person's everyday life and functioning. One's subjective age is shaped by metacognitive beliefs about aging, including both expectations about typical changes but most notably the awareness and interpretation of personal experiences. Subjective age has been described as multidimensional, aligning with life domains such as cognitive, social, and physical functioning. ...
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

NMDAR Neurotransmission Needed for Persistent Neuronal Firing: Potential Roles in Mental Disorders
The dorsolateral prefrontal cortex (dlPFC) generates the mental representations that are the foundation of abstract thought, and provides top-down regulation of emotion through projections to the medial PFC and cingulate cortices. Physiological recordings from dlPFC Delay cells have shown that the generation of mental representations during working memory relies on NMDAR neurotransmission, with surprisingly little contribution from AMPAR. Systemic administration of low “antidepressant” doses of the NMDAR antagonist, ketamine, erodes these representations and reduces dlPFC Delay cell firing. In contrast to the d...
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

A New Viewpoint on the Etiopathogenesis of Depression: Insights From the Neurophysiology of Deep Brain Stimulation in Parkinson's Disease and Treatment-Resistant Depression
(Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 9, 2021 Category: Psychiatry Source Type: research

Melatonin and Depression: A Translational Perspective From Animal Models to Clinical Studies
Daily rhythm of melatonin synchronizes the body to the light/dark environmental cycle. Several hypotheses have been raised to understand the intersections between melatonin and depression, in which changes in rest-activity and sleep patterns are prominent. This review describes key experimental and clinical evidence that link melatonin with the etiopathology and symptomatology of depressive states, its role in the follow up of therapeutic response to antidepressants, as well as the clinical evidence of melatonin as MDD treatment. Melatonin, as an internal temporal cue contributing to circadian organization and best studied...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Psychosocial Well-Being, Mental Health, and Available Supports in an Arab Enclave: Exploring Outcomes for Foreign-Born and U.S.-Born Adolescents
Conclusion: The existence of an immigrant paradox in this enclave setting was not supported. Instead, findings highlight the reciprocal value of peer-based mentorships and friendships between U.S.- and foreign-born students with similar cultural backgrounds, the importance of social and emotional curricula and cultural competency training within schools, and the gendered effects of acculturation. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Gene Expression Differences Between Young Adults Based on Trauma History and Post-traumatic Stress Disorder
Conclusions: This study uses gene network analyses to identify significant gene modules associated with PTSD, TE, and controls. On an individual gene level, we identified a large number of differentially expressed genes between PTSD-TE groups, a minority of which were also differentially expressed in the independent sample. We also demonstrate a lack of network module preservation between PTSD and TE, suggesting that the molecular signature of PTSD and trauma are likely independent of each other. Our results provide a basis for the identification of likely disease pathways and biomarkers involved in the etiology of PTSD. (...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Digital Communication Biomarkers of Mood and Diagnosis in Borderline Personality Disorder, Bipolar Disorder, and Healthy Control Populations
Conclusion: These results identify a general increase in phone call and SMS communications associated with self-reported manic symptoms and a diagnosis-moderated decrease in communications associated with depression in BD, but not BPD, participants. These findings may inform the development of clinical tools to aid diagnosis and remote symptom monitoring, as well as informing understanding of differential psychopathologies in BD and BPD. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Prenatal and Intrapartum Factors Associated With Infant Temperament: A Systematic Review
Conclusion: The findings support gene-environment interaction and biological mechanisms for developing infant temperament, suggesting the importance of ensuring a safe and comfortable environment for pregnant mothers, unborn infants, and families during pregnancy and delivery. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Looking Back to Move Forward: Reflections on the Strengths and Challenges of the COVID-19 UK Mental Health Research Response
In the face of the COVID-19 pandemic, the swift response of mental health research funders and institutions, service providers, and academics enabled progress toward understanding the mental health consequences. Nevertheless, there remains an urgent need to understand the true extent of the short- and long-term effects of the COVID-19 pandemic on mental health, necessitating ongoing research. Although the speed with which mental health researchers have mobilized to respond to the pandemic so far is to be commended, there are valid concerns as to whether speed may have compromised the quality of our work. As the pandemic co...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Evidence for an Interaction Between NEDD4 and Childhood Trauma on Clinical Characters of Schizophrenia With Family History of Psychosis
Conclusion: The study highlighted that the combined interaction of NEDD4 and CT may be associated with symptoms of schizophrenia especially for those with FH+. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Formal Thought Disorder and Self-Disorder: An Empirical Study
Background: Formal thought disorder was constitutively linked to the original concept of schizophrenia and has since been one of central features supporting its diagnosis. Bleuler considered formal thought disorder as a fundamental symptom of schizophrenia among other fundamental symptoms, including ego disorders. The contemporary concept of self-disorder represents a more developed, nuanced, and systematic approach to disturbances of self-experience than the Bleulerian concept of ego disorders. As fundamental symptoms, on Bleuler's account, are persistently present in every case, an association between these symptoms coul...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Parents Are Stressed! Patterns of Parent Stress Across COVID-19
Background: The Coronavirus Disease 2019 (COVID-19) pandemic has caused numerous unexpected challenges for many families, and these long-lasting demands likely contribute to higher stress for parents. The aim of this study was to describe changes in parent stress longitudinally from before (retrospective) to two timepoints during COVID-19. Stressors that influenced parenting and strategies to manage parenting difficulties at each timepoint during COVID-19 are also described.Methods: Parents (N = 433; 95% female) in the US with>1 child aged 5–18 years completed an online survey in May 2020 (T1; at the peak of stay-...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Targeting Personal Recovery of People With Complex Mental Health Needs: The Development of a Psychosocial Intervention Through User-Centered Design
This study describes the development process of a new intervention through user-centered design (UCD). UCD is an iterative process in which a product (in this case, an intervention) is developed in close cooperation with future users, such that the final product matches their needs. The design process included three phases: an analysis, design, and evaluation phase. In the analysis phase, the “problem” was defined, users' needs were identified, and design criteria were established. In the design phase, the collected information served as input to create a testable prototype using a process of design and redesig...
Source: Frontiers in Psychiatry - April 8, 2021 Category: Psychiatry Source Type: research

Computerized-Adaptive vs. Traditional Ratings of Depression and Suicidal Thoughts: An Assay Sensitivity Pilot Study in a Ketamine Clinical Trial
There is a public health need for improved suicide risk assessment tools. This pilot methodology study compared the assay sensitivity of computerized adaptive tests (CAT) of depression and suicidal ideation vs. traditional ratings in a randomized trial subgroup. The last 20 persons to enroll in a published ketamine trial in suicidal depression were studied. This subgroup received traditional and CAT ratings at baseline, 24 h post-infusion and follow-up week 2, 4, and 6: Hamilton Depression Rating Scale, Beck Depression Inventory, and Beck Scale for Suicidal Ideation vs. the CAT-Depression Inventory and CAT-Suicide Scale. R...
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Coping With the COVID-19 Pandemic: Examining Gender Differences in Stress and Mental Health Among University Students
The COVID-19 pandemic has imposed a wide variety of unprecedented challenges, many of which appear to be disproportionately affecting the mental health and well-being of young adults. While there is evidence to suggest university students experience high rates of mental health disorders, less is known about the specific impacts of the COVID-19 pandemic on student mental health and how they are coping with this stress. To address this gap, we conducted an online study among undergraduate students (n = 366) to examine the impact of the COVID-19 pandemic on academics, social isolation, and mental health, as well as the extent...
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Participants' Comprehension of the Informed Consent in an Epidemiological Study on Dementia Prevalence: A Qualitative Study
Conclusions: Participants and their proxies should be informed about both the scope of the informed consent process, and the content of the informed consent document in a focused, age-appropriate manner, while dispelling confusion about the purpose of research. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

What You Believe Can Affect How You Feel: Anger Among Caregivers of Elderly People With Dementia
Conclusion: Generally, lower caregiving anger was associated with: (1) being more empathic; (2) having a person-centered attitude; and (3) having a comprehensive understanding of dementia. The results of this study provide detailed suggestions for the development of anger management programs for caregivers of people with dementia. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Implementation of Psychodynamic Multifamily Groups for Severe Mental Illness: A Recovery-Oriented Approach
Conclusions: Multifamily groups represent a setting where patients can meet with other people and professionals in a free still structured way, and with not strictly therapeutic objectives. The high number of patients who attended alone suggests that such participation corresponds to a self-perceived need of open and free setting facilitating sharing of problems and solutions. The good tenure of the interventions, the high participation, and the feasibility in the long-term suggest that multifamily groups can be implemented in the mental health services of a large city, are sustainable over many years, and can represent a ...
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

The Sum of Fears in Cancer Patients Inside the Context of the COVID-19
This study aims to review and investigate the impact of COVID-19 on the mental health of cancer patients and indicate possible support strategies. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Problem Solving Therapy Improves Effortful Cognition in Major Depression
Conclusions: Patients with MD present effortful cognition dysfunction, and PST can improve effortful cognitive dysfunction. These findings suggest that the measurement of effortful cognition might be one of the indexes for the therapeutic effect of PST in MD. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Social Defeat, Psychotic Symptoms, and Crime in Young Caribbean Immigrants to Rotterdam
Background: The negative experience of being excluded from the majority group (social defeat) may be associated with psychosis in immigrants. The social defeat hypothesis is supported by the high frequency of perceived discrimination and acculturation problems in psychotic immigrants. In addition, social defeat may lead to crime through social problems such as unemployment, school dropout, a broken family structure, or psychotic symptoms.Methods: We assessed the association between social defeat and acculturation on the one hand and broadly defined psychotic symptoms and crime on the other in Caribbean immigrants to Rotter...
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Impaired Emotional Self-Referential Processing in First-Episode Schizophrenia
Impairments in self-representation are relevant to the expression of psychosis. To date, the characteristics and neural mechanisms of self-impairment in schizophrenia remain unclear. To this end, we used event-related potentials (ERPs) to measure brain activity in 56 first-episode patients with schizophrenia and 56 healthy controls. Participants judged personal trait adjectives regarding themselves, their mothers, or a public person, followed by an unexpected old/new recognition test. The recognition score for mother-reference adjectives was lower than that for self-reference adjectives in patients, while the control group...
Source: Frontiers in Psychiatry - April 7, 2021 Category: Psychiatry Source Type: research

Mental Health, Social and Emotional Well-Being, and Perceived Burdens of University Students During COVID-19 Pandemic Lockdown in Germany
Conclusion: The present study implies that University students are vulnerable and due to elevated depressive symptoms at risk, being hit hard by the pandemic, but are in general coping adaptively. Low-threshold online interventions promoting help-seeking and also targeting various mental health conditions might bridge the gap the COVID-19 pandemic opened up recently. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Magnetic Resonance-Guided Focused Ultrasound Surgery for Obsessive-Compulsive Disorders: Potential for use as a Novel Ablative Surgical Technique
Surgical treatment for psychiatric disorders, such as obsessive-compulsive disorder (OCD) and depression, using ablative techniques, such as cingulotomy and capsulotomy, have historically been controversial for a number of scientific, social, and ethical reasons. Recently, with the elucidation of anatomical and neurochemical substrates of brain function in healthy controls and patients with such disorders using various functional neuroimaging techniques, these criticisms are becoming less valid. Furthermore, by using new techniques, such as deep brain stimulation (DBS), and identifying more precise targets, beneficial effe...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Effort-Reward-Imbalance, Burnout, and Depression Among Psychiatrists 2006 and 2016-Changes After a Legislative Intervention
Conclusions: Our data show changes in workplace stress and mental health in psychiatrists in a decade in which a reduction in working hours has been required by law. These results can provide indications of effective prevention strategies in the professional context of physicians working in psychiatry. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

The Impact of COVID-19 Pandemic and Lockdown on Alcohol Consumption: A Perspective From Hair Analysis
Introduction and Aims: The increase in stress levels, social confinement, and addiction's physical consequences play an essential role in the proliferation of drug abuse. In this context, the Covid-19 pandemic produced remarkable effects on those individuals prone to addictions, especially to alcohol. Alcohol is linked to multiple dangerous conditions such as social issues, severe medical conditions, and road accidents. The determination of ethylglucuronide (EtG) in hair is frequently performed to test and monitor chronic excessive alcohol intake conditions, as it allows differentiation among low-risk/moderate drinkers, an...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

More Depression-Related Public Concern After the Suicide of a Pop Star in China: Evidence From the Online Big Data Platform
The objective of this study is to investigate the changes of search-engine query patterns to monitor this phenomenon based on the tragic suicide of a young Chinese pop star, Kimi Qiao.Methods: The daily search volume for depression was retrieved from both the Baidu Index (BDI) and the Sina MicroBlog Index (SMI). Besides, the daily BDI for suicide, schizophrenia, obsessive-compulsive disorder, common cold, stomach cancer, and liver cancer were collected for comparison. According to the time of Qiao's suicide, all data were divided into two periods (i.e., Period One from 1 September 2015 to 31 August 2016 while Period Two ra...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Functional Disability in Psychiatric Patients With Deliberate Self-Harm as Compared to a Clinical Control Group
Background: Deliberate self-harm (DSH) is a common behavior in psychiatric populations. However, little is known regarding how DSH impacts daily life. The concept of functional disability, adopted by the World Health Organization (WHO), refers to the impact of disorders on six domains of daily functioning. The aim of the current study was to explore the functional disability of psychiatric patients with DSH as compared to a psychiatric control group.Methods: 32 psychiatric patients with DSH and 31 psychiatric patients without DSH were assessed with regards to demographic information, functional disability, psychiatric illn...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Integration of the ICD-11 and DSM-5 Dimensional Systems for Personality Disorders Into a Unified Taxonomy With Non-overlapping Traits
The promise of replacing the diagnostic categories of personality disorder with a better-grounded system has been only partially met. We still need to understand whether our main dimensional taxonomies, those of the International Classification of Diseases, 11th Revision (ICD-11) and the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition (DSM-5), are the same or different, and elucidate whether a unified structure is possible. We also need truly independent pathological domains, as they have shown unacceptable overlap so far. To inquire into these points, the Personality Inventory for DSM-5 (PID-5) and th...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Cognitive Enhancers in Schizophrenia: A Systematic Review and Meta-Analysis of Alpha-7 Nicotinic Acetylcholine Receptor Agonists for Cognitive Deficits and Negative Symptoms
Conclusions: Current evidence is too weak to consider α7 nAChR agonists as an effective add-on treatment to antipsychotics to enhance cognition and negative symptoms. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Treatment for Major Depressive Disorder by Repetitive Transcranial Magnetic Stimulation in Different Parameters: A Randomized Double-Blinded Controlled Trial
Conclusions: It concludes that there were no statistical differences in the efficacy of rTMS between unilateral left and bilateral DLPFC, and between 5 and 10 Hz for treating MDD. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Long-Term Recidivism of Mentally Disordered Offenders Considered “Dangerous to the Public” in Switzerland
Conclusion: Our study showed that over a long-term time at risk this high-risk cohort showed a similar recidivism rate as many other studies with different cohorts. With appropriate management recidivism rates in high-risk offenders can be lowered allowing them being consecutively reintegrated into society. The finding that younger subjects have higher recidivism rate was reproduced in this population. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Examining Associations Between Child Abuse and Neglect Experiences With Emotion Regulation Difficulties Indicative of Adolescent Suicidal Ideation Risk
Conclusion: Relative to other types of abuse and neglect, emotional abuse may be differentially related to experiencing limited access to emotion regulation strategies, at the level indicative of suicide ideation risk. Clinical implications are discussed. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Markers of Prenatal Androgen Exposure Correlate With Online Sexual Compulsivity and Erectile Function in Young Men
Pornography addiction and sexual dysfunction are increasingly prevalent in young men. Previous studies suggest that prenatal androgen exposure plays a role in addiction and sexual functionality. Here, we tested whether lower second-to-fourth finger length ratio (2D:4D) and later age at spermarche, both putative indicators of higher androgen levels in utero, correlate with online sexual compulsivity (OSC scale of ISST), erectile function (IIEF-5), and ejaculatory control (PEPA) in 4,370 young men (age IQR: 25–26 years) of the Cohort Study on Substance Use Risk Factors. Statistical analyses revealed that lower 2D:4D co...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

Why Psychotropic Drugs Don't Cure Mental Illness —But Should They?
While pharmacological treatments for psychiatric disorders have offered great promise and have provided clinically meaningful symptom relief these treatments have had less effect on altering the course of these disorders. Research has provided many new insights about the effects of different psychotropic agents on the functions of various brain systems as investigators have embraced the “translational research model.” However, this theoretical approach of deconstructing complex behaviors into smaller measurable behavioral units and targeting brain systems that are hypothesized to underlie these discrete behavio...
Source: Frontiers in Psychiatry - April 6, 2021 Category: Psychiatry Source Type: research

The Severity of Dependence Scale (SDS) for Codeine: Preliminary Investigation of the Psychometric Properties of the SDS in an Online Sample of Codeine Users From the UK
Conclusions: The SDS was acceptable and feasible to use to assess probable psychological codeine dependence in an online sample of people using codeine containing medicines. SDS scores were associated with behaviors known to be indicators of codeine dependence. Studies are needed in well-defined populations of people who use codeine to test the different aspects of psychometry of the scale compared against “gold standard” criterion [a diagnosis according to the Diagnostic and Statistical Manual of Mental Disorders (DSM-5)]. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Posttraumatic Stress Symptoms, Quality of Life, and Stress Burden in Caregivers of Patients With Severe Mental Illness: An Underestimated Health Concern
Caregivers of patients with severe mental disorders experience a heavy stress burden that can manifest as psychiatric symptoms mimicking posttraumatic stress disorder (PTSD) and can negatively impact interpersonal relationships and work performance. The present study investigated the prevalence of PTSD symptoms, quality of life (QoL), and stress burden in caregivers of patients with severe mental illness. A total of 70 caregivers of severely mentally ill patients and 70 control subjects who were caregivers of patients with a chronic debilitating medical illness (cardiovascular disease) were recruited from university hospit...
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Cognitive Empathy as Imagination: Evidence From Reading the Mind in the Eyes in Autism and Schizotypy
How is cognitive empathy related to sociality, imagination, and other psychological constructs? How is it altered in disorders of human social cognition? We leveraged a large data set (1,168 students, 62% female) on the Reading the Mind in the Eyes test (RMET), the Autism Quotient (AQ), and the Schizotypal Personality Questionnaire (SPQ-BR) to test the hypotheses that the RMET, as a metric of cognitive empathy, reflects mainly social abilities, imagination, or both. RMET showed the expected female bias in performance, though only for eyes that expressed emotions and not for neutral expressions. RMET performance was signifi...
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Editorial: Post-traumatic Stress Disorder and Complex Traumatic Stress Disorder in Children and Adolescents
(Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Motivational Interviewing for Loved Ones in Early Psychosis: Development and Pilot Feasibility Trial of a Brief Psychoeducational Intervention for Caregivers
Treatment delay and non-adherence in first episode psychosis is a pressing public health problem. Ambivalence regarding psychiatric intervention and labeling among young people with psychosis is a contributing factor. For these individuals, caregivers often facilitate the pathway to care and support ongoing engagement and adherence. Caregivers describe distress and burden associated with this role. This manuscript describes the development and pilot feasibility testing of a motivational interviewing-derived communication training for caregivers of individuals with untreated or under-treated early course psychosis. Individu...
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Emotional Awareness in Schizophrenia Is Associated With Gray Matter Volume of Right Precuneus
Conclusion: Our findings suggest a relationship between gray matter volume of the right precuneus and deficits in understanding of emotional states of others in schizophrenia. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research

Case Report: Hidden Oral Squamous Cell Carcinoma in Oral Somatic Symptom Disorder
Conclusion: This case series suggests that psychiatrists must always be careful in regarding BMS as somatic symptom disorder and be cautious of the possibility of OSCC, especially in elderly patients. (Source: Frontiers in Psychiatry)
Source: Frontiers in Psychiatry - April 1, 2021 Category: Psychiatry Source Type: research