Social isolation and psychosis: an investigation of social interactions and paranoia in daily life
Eur Arch Psychiatry Clin Neurosci. 2021 Jun 15. doi: 10.1007/s00406-021-01278-4. Online ahead of print.ABSTRACTSocial isolation has been suggested to foster paranoia. Here we investigate whether social company (i.e., being alone vs. not) and its nature (i.e., stranger/distant vs. familiar other) affects paranoia differently depending on psychosis risk. Social interactions and paranoid thinking in daily life were investigated in 29 patients with clinically stable non-affective psychotic disorders, 20 first-degree relatives, and 26 controls (n = 75), using the experience sampling method (ESM). ESM was completed up to ten tim...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2021 Category: Psychiatry Authors: Anne-Kathrin J Fett Esther Hanssen Marlie Eemers Emmanuelle Peters Sukhi S Shergill Source Type: research

Social isolation and psychosis: an investigation of social interactions and paranoia in daily life
AbstractSocial isolation has been suggested to foster paranoia. Here we investigate whether social company (i.e., being alone vs. not) and its nature (i.e., stranger/distant vs. familiar other) affects paranoia differently depending on psychosis risk. Social interactions and paranoid thinking in daily life were investigated in 29 patients with clinically stable non-affective psychotic disorders, 20 first-degree relatives, and 26 controls (n = 75), using the experience sampling method (ESM). ESM was completed up to ten times daily for 1 week. Patients experienced marginally greater paranoia than relatives...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2021 Category: Neuroscience Source Type: research

Childhood trauma mediates repetitive transcranial magnetic stimulation efficacy in major depressive disorder
Eur Arch Psychiatry Clin Neurosci. 2021 Jun 12. doi: 10.1007/s00406-021-01279-3. Online ahead of print.ABSTRACTChildhood trauma is one of the most prominent risk factors in developing major depressive disorder (MDD) and may lead to unfavorable outcomes of pharmacotherapy and psychotherapy in MDD. While how it modulates the treatment outcome of the repetitive transcranial magnetic stimulation (rTMS) and how sex difference may play a role in mediating this relationship remain unknown. To evaluate this question, 52 (38 women) MDD patients were treated with 10 Hz rTMS to the left dorsolateral prefrontal cortex (lDLPFC). The ex...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 12, 2021 Category: Psychiatry Authors: Yu-Ting Hu Xi-Wen Hu Jin-Fang Han Jian-Feng Zhang Ying-Ying Wang Annemarie Wolff Sara Tremblay Zhong-Lin Tan Georg Northoff Source Type: research

Childhood trauma mediates repetitive transcranial magnetic stimulation efficacy in major depressive disorder
AbstractChildhood trauma is one of the most prominent risk factors in developing major depressive disorder (MDD) and may lead to unfavorable outcomes of pharmacotherapy and psychotherapy in MDD. While how it modulates the treatment outcome of the repetitive transcranial magnetic stimulation (rTMS) and how sex difference may play a role in mediating this relationship remain unknown. To evaluate this question, 52 (38 women) MDD patients were treated with 10  Hz rTMS to the left dorsolateral prefrontal cortex (lDLPFC). The experience of childhood trauma was quantified by the Childhood Traumatic Questionnaire (CTQ). The d...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 12, 2021 Category: Neuroscience Source Type: research

Correction to: Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball-incongruence paradigm
Eur Arch Psychiatry Clin Neurosci. 2021 Jun 9. doi: 10.1007/s00406-021-01276-6. Online ahead of print.NO ABSTRACTPMID:34106295 | DOI:10.1007/s00406-021-01276-6 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 9, 2021 Category: Psychiatry Authors: Lisa Rauer Sarah Trost Aleksandra Petrovic Oliver Gruber Source Type: research

Correction to: Cortical activation abnormalities in bipolar and schizophrenia patients in a combined oddball –incongruence paradigm
A correction to this paper has been published: https://doi.org/10.1007/s00406-021-01276-6 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 9, 2021 Category: Neuroscience Source Type: research

Correction to: Current clinical practice of electroconvulsive therapy and repetitive transcranial magnetic stimulation in psychiatry, a German sample
Eur Arch Psychiatry Clin Neurosci. 2021 Jun 5. doi: 10.1007/s00406-021-01275-7. Online ahead of print.NO ABSTRACTPMID:34091706 | DOI:10.1007/s00406-021-01275-7 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 6, 2021 Category: Psychiatry Authors: Charles Tim äus Jonathan Vogelgsang Bernhard Kis Katrin Radenbach Claus Wolff-Menzler Kiriaki Mavridou Stephan Gy ßer Philipp Hessmann Jens Wiltfang Source Type: research

Correction to: Current clinical practice of electroconvulsive therapy and repetitive transcranial magnetic stimulation in psychiatry, a German sample
A correction to this paper has been published: https://doi.org/10.1007/s00406-021-01275-7 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 5, 2021 Category: Neuroscience Source Type: research

Two-stage mental health survey of first-line medical staff after ending COVID-19 epidemic assistance and isolation
Eur Arch Psychiatry Clin Neurosci. 2021 May 18:1-13. doi: 10.1007/s00406-021-01239-x. Online ahead of print.ABSTRACTFacing with COVID-19 epidemic such a catastrophic health emergency, the mental health status of medical staff deserves attention. We conducted a two-stage of psychological status monitoring after the end of the assistance and 14 days of isolation, further targeted the vulnerable groups in need of intervention. The study is a cross-sectional survey on 1156 Yunnan medical staff aid to Hubei. Used Cluster sampling method to collect data at 2 time points (at the end of returning from Wuhan and the 14th day of iso...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 19, 2021 Category: Psychiatry Authors: Li Xu Dingyun You Chengyu Li Xiyu Zhang Runxu Yang Chuanyuan Kang Nianshi Wang Yuxiong Jin Jing Yuan Chao Li Yujun Wei Ye Li Jianzhong Yang Source Type: research

Two-stage mental health survey of first-line medical staff after ending COVID-19 epidemic assistance and isolation
Eur Arch Psychiatry Clin Neurosci. 2021 May 18. doi: 10.1007/s00406-021-01239-x. Online ahead of print.ABSTRACTFacing with COVID-19 epidemic such a catastrophic health emergency, the mental health status of medical staff deserves attention. We conducted a two-stage of psychological status monitoring after the end of the assistance and 14 days of isolation, further targeted the vulnerable groups in need of intervention. The study is a cross-sectional survey on 1156 Yunnan medical staff aid to Hubei. Used Cluster sampling method to collect data at 2 time points (at the end of returning from Wuhan and the 14th day of isolatio...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 19, 2021 Category: Psychiatry Authors: Li Xu Dingyun You Chengyu Li Xiyu Zhang Runxu Yang Chuanyuan Kang Nianshi Wang Yuxiong Jin Jing Yuan Chao Li Yujun Wei Ye Li Jianzhong Yang Source Type: research

Reply to Letter "Transcranial alternating current stimulation (tACS) as a treatment for fibromyalgia syndrome?" by Fr öhlich and Riddle
Eur Arch Psychiatry Clin Neurosci. 2021 May 17. doi: 10.1007/s00406-021-01271-x. Online ahead of print.NO ABSTRACTPMID:34002242 | DOI:10.1007/s00406-021-01271-x (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - May 18, 2021 Category: Psychiatry Authors: Alessandra Del Felice Margherita Bertuccelli Maria Rubega Manuela Cattelan Stefano Masiero Source Type: research

Two-stage mental health survey of first-line medical staff after ending COVID-19 epidemic assistance and isolation
AbstractFacing with COVID-19 epidemic such a catastrophic health emergency, the mental health status of medical staff deserves attention. We conducted a two-stage of psychological status monitoring after the end of the assistance and 14  days of isolation, further targeted the vulnerable groups in need of intervention. The study is a cross-sectional survey on 1156 Yunnan medical staff aid to Hubei. Used Cluster sampling method to collect data at 2 time points (at the end of returning from Wuhan and the 14th day of isolation), from March 18, 2020 to April 6, 2020. Female and nurse had higher rates of depressive symptom...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 18, 2021 Category: Neuroscience Source Type: research

Reply to Letter “Transcranial alternating current stimulation (tACS) as a treatment for fibromyalgia syndrome?” by Fröhlich and Riddle
(Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - May 17, 2021 Category: Neuroscience Source Type: research

A network analysis of interoception, self-awareness, empathy, alexithymia, and autistic traits
Eur Arch Psychiatry Clin Neurosci. 2021 May 13. doi: 10.1007/s00406-021-01274-8. Online ahead of print.ABSTRACTAltered interoception has been consistently found in people with autism spectrum disorder (ASD), and this impairment may contribute to social cognitive dysfunctions. However, little is known regarding the intercorrelations between interoceptive sensibility, autistic, alexithymic, empathic, and self-related traits. We recruited 1360 non-clinical college students and adults to investigate the complex inter-relationship between these variables using network analysis. The resultant network revealed patterns connecting...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 14, 2021 Category: Psychiatry Authors: Han-Xue Yang Hui-Xin Hu Yi-Jing Zhang Yi Wang Simon S Y Lui Raymond C K Chan Source Type: research

Increased peripheral inflammation in schizophrenia is associated with worse cognitive performance and related cortical thickness reductions
AbstractWhile the biological substrates of brain and behavioural changes in persons with schizophrenia remain unclear, increasing evidence implicates that inflammation is involved. In schizophrenia, including first-episode psychosis and anti-psychotic na ïve patients, there are numerous reports of increased peripheral inflammation, cognitive deficits and neuropathologies such as cortical thinning. Research defining the relationship between inflammation and schizophrenia symptomatology and neuropathology is needed. Therefore, we analysed the level o f C-reactive protein (CRP), a peripheral inflammation marker, and its ...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 13, 2021 Category: Neuroscience Source Type: research

C1q, a small molecule with high impact on brain development: putative role for aging processes and the occurrence of Alzheimer's disease
Eur Arch Psychiatry Clin Neurosci. 2021 May 13. doi: 10.1007/s00406-021-01273-9. Online ahead of print.NO ABSTRACTPMID:33983513 | DOI:10.1007/s00406-021-01273-9 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - May 13, 2021 Category: Psychiatry Authors: Christian Rupprecht Rainer Rupprecht Gerhard Rammes Source Type: research

C1q, a small molecule with high impact on brain development: putative role for aging processes and the occurrence of Alzheimer ’s disease
(Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - May 13, 2021 Category: Neuroscience Source Type: research

Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met  polymorphism on antidepressant response to low-dose ketamine infusion
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01264-w. Online ahead of print.ABSTRACTEvidence suggests that levels of treatment refractoriness and brain-derived neurotrophic factor (BDNF) rs6265 polymorphism are related to the antidepressant effects of conventional antidepressants and repetitive transcranial magnetic stimulation. However, whether these factors are associated with the antidepressant effects of low-dose ketamine remains unclear. In total, 71 patients with treatment-resistant depression (TRD) were randomized to 0.5 mg/kg ketamine, 0.2 mg/kg ketamine, and saline control infusion groups...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Mu-Hong Chen Wei-Chen Lin Shih-Jen Tsai Cheng-Ta Li Chih-Ming Cheng Hui-Ju Wu Ya-Mei Bai Chen-Jee Hong Pei-Chi Tu Tung-Ping Su Source Type: research

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01263-x. Online ahead of print.ABSTRACTFormal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whether there are differences in pFTD on a single symptom level between acutely ill patients with SZ and MA, which cannot be attributed to cognitive impairment. We compared single pFTD symptoms in two groups of acutely ill patients with ICD-10 bipolar mania and schizophrenia, closely matched for age, sex, pFTD TALD score, ve...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Tilo Kircher Frederike Stein Arne Nagels Source Type: research

Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met  polymorphism on antidepressant response to low-dose ketamine infusion
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01264-w. Online ahead of print.ABSTRACTEvidence suggests that levels of treatment refractoriness and brain-derived neurotrophic factor (BDNF) rs6265 polymorphism are related to the antidepressant effects of conventional antidepressants and repetitive transcranial magnetic stimulation. However, whether these factors are associated with the antidepressant effects of low-dose ketamine remains unclear. In total, 71 patients with treatment-resistant depression (TRD) were randomized to 0.5 mg/kg ketamine, 0.2 mg/kg ketamine, and saline control infusion groups...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Mu-Hong Chen Wei-Chen Lin Shih-Jen Tsai Cheng-Ta Li Chih-Ming Cheng Hui-Ju Wu Ya-Mei Bai Chen-Jee Hong Pei-Chi Tu Tung-Ping Su Source Type: research

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01263-x. Online ahead of print.ABSTRACTFormal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whether there are differences in pFTD on a single symptom level between acutely ill patients with SZ and MA, which cannot be attributed to cognitive impairment. We compared single pFTD symptoms in two groups of acutely ill patients with ICD-10 bipolar mania and schizophrenia, closely matched for age, sex, pFTD TALD score, ve...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Tilo Kircher Frederike Stein Arne Nagels Source Type: research

Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met  polymorphism on antidepressant response to low-dose ketamine infusion
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01264-w. Online ahead of print.ABSTRACTEvidence suggests that levels of treatment refractoriness and brain-derived neurotrophic factor (BDNF) rs6265 polymorphism are related to the antidepressant effects of conventional antidepressants and repetitive transcranial magnetic stimulation. However, whether these factors are associated with the antidepressant effects of low-dose ketamine remains unclear. In total, 71 patients with treatment-resistant depression (TRD) were randomized to 0.5 mg/kg ketamine, 0.2 mg/kg ketamine, and saline control infusion groups...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Mu-Hong Chen Wei-Chen Lin Shih-Jen Tsai Cheng-Ta Li Chih-Ming Cheng Hui-Ju Wu Ya-Mei Bai Chen-Jee Hong Pei-Chi Tu Tung-Ping Su Source Type: research

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01263-x. Online ahead of print.ABSTRACTFormal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whether there are differences in pFTD on a single symptom level between acutely ill patients with SZ and MA, which cannot be attributed to cognitive impairment. We compared single pFTD symptoms in two groups of acutely ill patients with ICD-10 bipolar mania and schizophrenia, closely matched for age, sex, pFTD TALD score, ve...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Tilo Kircher Frederike Stein Arne Nagels Source Type: research

Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met  polymorphism on antidepressant response to low-dose ketamine infusion
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01264-w. Online ahead of print.ABSTRACTEvidence suggests that levels of treatment refractoriness and brain-derived neurotrophic factor (BDNF) rs6265 polymorphism are related to the antidepressant effects of conventional antidepressants and repetitive transcranial magnetic stimulation. However, whether these factors are associated with the antidepressant effects of low-dose ketamine remains unclear. In total, 71 patients with treatment-resistant depression (TRD) were randomized to 0.5 mg/kg ketamine, 0.2 mg/kg ketamine, and saline control infusion groups...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Mu-Hong Chen Wei-Chen Lin Shih-Jen Tsai Cheng-Ta Li Chih-Ming Cheng Hui-Ju Wu Ya-Mei Bai Chen-Jee Hong Pei-Chi Tu Tung-Ping Su Source Type: research

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01263-x. Online ahead of print.ABSTRACTFormal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whether there are differences in pFTD on a single symptom level between acutely ill patients with SZ and MA, which cannot be attributed to cognitive impairment. We compared single pFTD symptoms in two groups of acutely ill patients with ICD-10 bipolar mania and schizophrenia, closely matched for age, sex, pFTD TALD score, ve...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Tilo Kircher Frederike Stein Arne Nagels Source Type: research

Effects of treatment refractoriness and brain-derived neurotrophic factor Val66Met  polymorphism on antidepressant response to low-dose ketamine infusion
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01264-w. Online ahead of print.ABSTRACTEvidence suggests that levels of treatment refractoriness and brain-derived neurotrophic factor (BDNF) rs6265 polymorphism are related to the antidepressant effects of conventional antidepressants and repetitive transcranial magnetic stimulation. However, whether these factors are associated with the antidepressant effects of low-dose ketamine remains unclear. In total, 71 patients with treatment-resistant depression (TRD) were randomized to 0.5 mg/kg ketamine, 0.2 mg/kg ketamine, and saline control infusion groups...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Mu-Hong Chen Wei-Chen Lin Shih-Jen Tsai Cheng-Ta Li Chih-Ming Cheng Hui-Ju Wu Ya-Mei Bai Chen-Jee Hong Pei-Chi Tu Tung-Ping Su Source Type: research

Differences in single positive formal thought disorder symptoms between closely matched acute patients with schizophrenia and mania
Eur Arch Psychiatry Clin Neurosci. 2021 May 7. doi: 10.1007/s00406-021-01263-x. Online ahead of print.ABSTRACTFormal thought disorders (FTD) are a hallmark diagnostic feature of schizophrenia (SZ) and (bipolar) mania (MA). FTD can be separated into positive (pFTD) and negative dimensions. It is unclear whether there are differences in pFTD on a single symptom level between acutely ill patients with SZ and MA, which cannot be attributed to cognitive impairment. We compared single pFTD symptoms in two groups of acutely ill patients with ICD-10 bipolar mania and schizophrenia, closely matched for age, sex, pFTD TALD score, ve...
Source: European Archives of Psychiatry and Clinical Neuroscience - May 7, 2021 Category: Psychiatry Authors: Tilo Kircher Frederike Stein Arne Nagels Source Type: research