The impact of the COVID-19 pandemic on perceptions of social relationships, negative affect, and paranoid ideation
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 13. doi: 10.1007/s00406-024-01777-0. Online ahead of print.ABSTRACTThe COVID-19 pandemic contributed to worsening mental health across the globe. The pandemic may have been especially impactful on those experiencing heightened psychosis spectrum symptomatology given greater pre-pandemic social isolation and increased vulnerability to stress. Yet, few studies exploring the impact of the COVID-19 pandemic on perceptions of social relationships and mental health have sampled individuals high in psychosis spectrum symptomatology, including those with psychosis spectrum disorders. Uti...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 13, 2024 Category: Psychiatry Authors: Ryan D Orth Christina L G Savage Melanie E Bennett Jack J Blanchard Source Type: research

Borderline personality disorder vs. schizophrenia spectrum disorders in young people recruited within an "Early Intervention in Psychosis" service: clinical and outcome comparisons
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 12. doi: 10.1007/s00406-024-01772-5. Online ahead of print.ABSTRACTBorderline Personality Disorder (BPD) is under-recognized in First-Episode Psychosis (FEP) and its psychotic manifestations are difficult to differentiate from Schizophrenia Spectrum Disorders (SSD). The aim of this investigation was to compare clinical, sociodemographic, and outcome characteristics between FEP patients with BPD vs. FEP subjects with SSD both at baseline and across a 2-year follow-up period. Participants completed the Health of the Nation Outcome Scale (HoNOS), the Positive And Negative Syndrome S...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 13, 2024 Category: Psychiatry Authors: Lorenzo Pelizza Emanuela Leuci Emanuela Quattrone Silvia Azzali Giuseppina Paulillo Simona Pupo Pietro Pellegrini Lorenzo Gammino Arianna Biancalani Marco Menchetti Source Type: research

The impact of the COVID-19 pandemic on perceptions of social relationships, negative affect, and paranoid ideation
AbstractThe COVID-19 pandemic contributed to worsening mental health across the globe. The pandemic may have been especially impactful on those experiencing heightened psychosis spectrum symptomatology given greater pre-pandemic social isolation and increased vulnerability to stress. Yet, few studies exploring the impact of the COVID-19 pandemic on perceptions of social relationships and mental health have sampled individuals high in psychosis spectrum symptomatology, including those with psychosis spectrum disorders. Utilizing a mixed transdiagnostic community sample enriched for psychotic spectrum disorders, this longitu...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 13, 2024 Category: Neuroscience Source Type: research

Association of empathy with clinical symptoms and cognitive function in chronic schizophrenia patients with and without suicide attempts
AbstractCognitive impairment is recognized as a risk factor for suicide in schizophrenia (SZ) patients. Despite empathy being an important aspect of social cognition, the association between suicidal behavior and empathy has received little attention. We aimed to compare empathy and neurocognition in SZ patients with and without suicide attempts (SAs), and to explore the relationship between empathy, neurocognition, and clinical symptoms in SZ patients with and without SAs. Data on SAs and socio-demographic characteristics were collected from 628 chronic SZ patients. The patients ’ symptomatology was measured by the Posi...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 13, 2024 Category: Neuroscience Source Type: research

The impact of the COVID-19 pandemic on perceptions of social relationships, negative affect, and paranoid ideation
AbstractThe COVID-19 pandemic contributed to worsening mental health across the globe. The pandemic may have been especially impactful on those experiencing heightened psychosis spectrum symptomatology given greater pre-pandemic social isolation and increased vulnerability to stress. Yet, few studies exploring the impact of the COVID-19 pandemic on perceptions of social relationships and mental health have sampled individuals high in psychosis spectrum symptomatology, including those with psychosis spectrum disorders. Utilizing a mixed transdiagnostic community sample enriched for psychotic spectrum disorders, this longitu...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 13, 2024 Category: Neuroscience Source Type: research

Correlative relationship between body mass index and heart rate variability in psychiatric disorders
This study aimed to examine how obesity (measured with the body mass index [BMI]) affects HRV and determine whether the effect varies among different psychiatric disorders. We recruited 3159 consecutive patients, including 1744 with schizophrenia, 966 with mood disorders, and 449 with anxiety disorders. Patients were divided into four groups based on BMI: underweight (< 18.5), normal weight (18.5-23.9), overweight (24-27.9), and obese (≥ 28). The cardiovascular status was assessed using several time- and frequency-based HRV indicators, measured via electrocardiogram signals recorded for 5 min. The mean BMI of the part...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 12, 2024 Category: Psychiatry Authors: WenZheng Wang LinLin Zhou Qiang Hu YuQing Gao YanYan Wei XiaoChen Tang YeGang Hu LiHua Xu HaiChun Liu ZiXuan Wang Tao Chen ChunBo Li HaiSu Wu JiJun Wang TianHong Zhang Source Type: research

Correlative relationship between body mass index and heart rate variability in psychiatric disorders
This study aimed to examine how obesity (measured with the body mass index [BMI]) affects HRV and determine whether the effect varies among different psychiatric disorders. We recruited 3159 consecutive patients, including 1744 with schizophrenia, 966 with mood disorders, and 449 with anxiety disorders. Patients were divided into four groups based on BMI: underweight (<  18.5), normal weight (18.5–23.9), overweight (24–27.9), and obese (≥ 28). The cardiovascular status was assessed using several time- and frequency-based HRV indicators, measured via electrocardiogram signals recorded for 5 min. The mean BMI o...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 12, 2024 Category: Neuroscience Source Type: research

Borderline personality disorder vs. schizophrenia spectrum disorders in young people recruited within an “Early Intervention in Psychosis” service: clinical and outcome comparisons
AbstractBorderline Personality Disorder (BPD) is under-recognized in First-Episode Psychosis (FEP) and its psychotic manifestations are difficult to differentiate from Schizophrenia Spectrum Disorders (SSD). The aim of this investigation was to compare clinical, sociodemographic, and outcome characteristics between FEP patients with BPD vs. FEP subjects with SSD both at baseline and across a 2-year follow-up period. Participants completed the Health of the Nation Outcome Scale (HoNOS), the Positive And Negative Syndrome Scale (PANSS), and the Global Assessment of Functioning (GAF) scale both at entry and every 12  months ...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 12, 2024 Category: Neuroscience Source Type: research

Demographic, biochemical, clinical,  and cognitive symptom differences between smokers and non-smokers in Chinese older male patients with chronic schizophrenia
CONCLUSIONS: Elderly Chinese men with schizophrenia have a higher percentage of smokers, and although smoking can reduce their plasma albumin levels, it does contribute to the prevention of negative symptoms.PMID:38462585 | DOI:10.1007/s00406-024-01762-7 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: Wei Li Ling Yue Shifu Xiao Source Type: research

Polypharmacy in psychiatry and weight gain: longitudinal study of 832 patients hospitalized for depression or schizophrenia, along with data of 3180 students from Europe, the U.S., South America, and China
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 10. doi: 10.1007/s00406-024-01767-2. Online ahead of print.ABSTRACTEpidemiologic data indicate that overweight and obesity are on the rise worldwide. Psychiatric patients are particularly vulnerable in this respect as they have an increased prevalence of overweight and obesity, and often experience rapid, highly undesirable weight gain under psychotropic drug treatment. Current treatment strategies in psychiatry are oriented towards polypharmacy, so that the information on drug-induced weight gain from earlier monotherapy studies is of very limited validity. We have analyzed the ...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: H H Stassen S Bachmann R Bridler K Cattapan E Seifritz Source Type: research

The neurobiological effects of childhood maltreatment on brain structure, function, and attachment
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 11. doi: 10.1007/s00406-024-01779-y. Online ahead of print.ABSTRACTChildhood maltreatment is a risk factor for psychopathologies, and influences brain development at specific periods, particularly during early childhood and adolescence. This narrative review addresses phenotypic alterations in sensory systems associated with specific types of childhood maltreatment exposure, periods of vulnerability to the neurobiological effects of maltreatment, and the relationships between childhood maltreatment and brain structure, function, connectivity, and network architecture; psychopatho...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: Akemi Tomoda Shota Nishitani Shinichiro Takiguchi Takashi X Fujisawa Toshiro Sugiyama Martin H Teicher Source Type: research

Demographic, biochemical, clinical,  and cognitive symptom differences between smokers and non-smokers in Chinese older male patients with chronic schizophrenia
CONCLUSIONS: Elderly Chinese men with schizophrenia have a higher percentage of smokers, and although smoking can reduce their plasma albumin levels, it does contribute to the prevention of negative symptoms.PMID:38462585 | DOI:10.1007/s00406-024-01762-7 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: Wei Li Ling Yue Shifu Xiao Source Type: research

Polypharmacy in psychiatry and weight gain: longitudinal study of 832 patients hospitalized for depression or schizophrenia, along with data of 3180 students from Europe, the U.S., South America, and China
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 10. doi: 10.1007/s00406-024-01767-2. Online ahead of print.ABSTRACTEpidemiologic data indicate that overweight and obesity are on the rise worldwide. Psychiatric patients are particularly vulnerable in this respect as they have an increased prevalence of overweight and obesity, and often experience rapid, highly undesirable weight gain under psychotropic drug treatment. Current treatment strategies in psychiatry are oriented towards polypharmacy, so that the information on drug-induced weight gain from earlier monotherapy studies is of very limited validity. We have analyzed the ...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: H H Stassen S Bachmann R Bridler K Cattapan E Seifritz Source Type: research

The neurobiological effects of childhood maltreatment on brain structure, function, and attachment
Eur Arch Psychiatry Clin Neurosci. 2024 Mar 11. doi: 10.1007/s00406-024-01779-y. Online ahead of print.ABSTRACTChildhood maltreatment is a risk factor for psychopathologies, and influences brain development at specific periods, particularly during early childhood and adolescence. This narrative review addresses phenotypic alterations in sensory systems associated with specific types of childhood maltreatment exposure, periods of vulnerability to the neurobiological effects of maltreatment, and the relationships between childhood maltreatment and brain structure, function, connectivity, and network architecture; psychopatho...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Psychiatry Authors: Akemi Tomoda Shota Nishitani Shinichiro Takiguchi Takashi X Fujisawa Toshiro Sugiyama Martin H Teicher Source Type: research

The neurobiological effects of childhood maltreatment on brain structure, function, and attachment
AbstractChildhood maltreatment is a risk factor for psychopathologies, and influences brain development at specific periods, particularly during early childhood and adolescence. This narrative review addresses phenotypic alterations in sensory systems associated with specific types of childhood maltreatment exposure, periods of vulnerability to the neurobiological effects of maltreatment, and the relationships between childhood maltreatment and brain structure, function, connectivity, and network architecture; psychopathology; and resilience. It also addresses neurobiological alterations associated with maternal communicat...
Source: European Archives of Psychiatry and Clinical Neuroscience - March 11, 2024 Category: Neuroscience Source Type: research