European Archives of Psychiatry and Clinical Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism
In conclusion, plasma NFL level was increased in patients with AD and reduced after early abstinence. Reduction in NFL level corroborated well with the improvement of clinical symptoms. TheALDH2 rs671 polymorphism may play a role in modulating the extent of neuroaxonal injury and its recovery. (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Neuroscience Source Type: research

Suicidal ideation in Chinese patients with chronic schizophrenia: prevalence, clinical correlates, and relationship with alexithymia
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 13. doi: 10.1007/s00406-023-01630-w. Online ahead of print.ABSTRACTSuicidal ideation (SI) is common among people with schizophrenia. However, it has received less attention than suicide attempts (SA), especially in the Chinese population. Alexithymia is a well-established risk factor for SI across different populations. Nevertheless, very few studies evaluated their relationship in schizophrenia patients. We aimed to determine the prevalence and clinical correlates of SI and its relationship with alexithymia in 812 Chinese chronic schizophrenia inpatients. We assessed SI, clinica...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 13, 2023 Category: Psychiatry Authors: Yanan Zhou Pu Peng Ning Yuan Yifan Xiong Yinli Luo Lini Liu Rongrong Tan Wei Nie Yuan Wang Xiangyang Zhang Source Type: research

Suicidal ideation in Chinese patients with chronic schizophrenia: prevalence, clinical correlates, and relationship with alexithymia
AbstractSuicidal ideation (SI) is common among people with schizophrenia. However, it has received less attention than suicide attempts (SA), especially in the Chinese population. Alexithymia is a well-established risk factor for SI across different populations. Nevertheless, very few studies evaluated their relationship in schizophrenia patients. We aimed to determine the prevalence and clinical correlates of SI and its relationship with alexithymia in 812 Chinese chronic schizophrenia inpatients. We assessed SI, clinical symptoms, and alexithymia by the Beck Scale for Suicidal Ideation, the Positive and Negative Syndrome...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 13, 2023 Category: Neuroscience Source Type: research

Schizophrenia polygenic risk score in psychosis proneness
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 10. doi: 10.1007/s00406-023-01633-7. Online ahead of print.ABSTRACTSchizophrenia (SZ) is a complex disorder with a highly polygenic inheritance. It can be conceived as the extreme expression of a continuum of traits that are present in the general population often broadly referred to as schizotypy. However, it is still poorly understood how these traits overlap genetically with the disorder. We investigated whether polygenic risk for SZ is associated with these disorder-related phenotypes (schizotypy, psychotic-like experiences, and subclinical psychopathology) in a sample of 253...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 10, 2023 Category: Psychiatry Authors: Patricia Mas-Bermejo Sergi Papiol Marc Via Paula Rovira Pilar Torrecilla Thomas R Kwapil Neus Barrantes-Vidal Araceli Rosa Source Type: research

Schizophrenia polygenic risk score in psychosis proneness
AbstractSchizophrenia (SZ) is a complex disorder with a highly polygenic inheritance. It can be conceived as the extreme expression of a continuum of traits that are present in the general population often broadly referred to as schizotypy. However, it is still poorly understood how these traits overlap genetically with the disorder. We investigated whether polygenic risk for SZ is associated with these disorder-related phenotypes (schizotypy, psychotic-like experiences, and subclinical psychopathology) in a sample of 253 non-clinically identified participants. Polygenic risk scores (PRSs) were constructed based on the lat...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 10, 2023 Category: Neuroscience Source Type: research

Cerebral blood flow changes in schizophrenia patients with auditory verbal hallucinations during low-frequency rTMS treatment
In this study, we used arterial spin labeling (ASL) to investigate changes in brain perfusion in schizophrenia patients with AVH, and their associations with clinical improvement following low-frequency rTMS treatment applied to the left temporoparietal junction area. We observed improvements in clinical symptoms (e.g., positive symptoms and AVH) and certain neurocognitive functions (e.g., verbal learning and visual learning) following treatment. Furthermore, at baseline, the patients showed reductions in CBF in regions associated with language, sensory, and cognition compared to controls, primarily located in the prefront...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 7, 2023 Category: Neuroscience Source Type: research

Network analysis of discrete emotional states measured via ecological momentary assessment in schizophrenia
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 6. doi: 10.1007/s00406-023-01623-9. Online ahead of print.ABSTRACTPrior studies demonstrate that schizophrenia (SZ) is associated with abnormalities in positive and negative emotional experience that predict clinical presentation. However, it is unclear whether specific discrete emotions within the broader positive/negative categories are driving those symptom associations. Further, it is also unclear whether specific emotions contribute to symptoms in isolation or via networks of emotional states that dynamically interact across time. The current study used network analysis to e...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 6, 2023 Category: Psychiatry Authors: Gregory P Strauss Farnaz Zamani-Esfahlani Ian M Raugh Lauren Luther Hiroki Sayama Source Type: research

Cerebral blood flow changes in schizophrenia patients with auditory verbal hallucinations during low-frequency rTMS treatment
In this study, we used arterial spin labeling (ASL) to investigate changes in brain perfusion in schizophrenia patients with AVH, and their associations with clinical improvement following low-frequency rTMS treatment applied to the left temporoparietal junction area. We observed improvements in clinical symptoms (e.g., positive symptoms and AVH) and certain neurocognitive functions (e.g., verbal learning and visual learning) following treatment. Furthermore, at baseline, the patients showed reductions in CBF in regions associated with language, sensory, and cognition compared to controls, primarily located in the prefront...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 6, 2023 Category: Psychiatry Authors: Yuanjun Xie Muzhen Guan Zhongheng Wang Zhujing Ma Peng Fang Huaning Wang Source Type: research