European Archives of Psychiatry and Clinical Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Interactions between overweight/obesity and alcohol dependence impact human brain white matter microstructure: evidence from DTI
This study aimed to investigate the possible interactions between alcohol dependence and overweight/obesity on white matter microstructure in the human brain. A total of 60 inpatients with alcohol dependence during early abstinence (44 normal weight and 16 overweight/obese) and 65 controls (42 normal weight and 23 overweight/obese) were included. The diffusion tensor imaging (DTI) measures [fractional anisotropy (FA) and radial diffusivity (RD)] of the white matter microstructure were compared between groups. We observed significant interactive effects between alcohol dependence and overweight/obesity on DTI measures in se...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 25, 2024 Category: Psychiatry Authors: Hai-Ling Cao Wei Wei Ya-Jing Meng Ren-Hao Deng Xiao-Jing Li Wei Deng Yan-Song Liu Zhen Tang Xiang-Dong Du Andrew J Greenshaw Ming-Li Li Tao Li Wan-Jun Guo Source Type: research

Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
Eur Arch Psychiatry Clin Neurosci. 2024 Feb 14. doi: 10.1007/s00406-023-01725-4. Online ahead of print.ABSTRACTThe hypothalamus is key to body homeostasis, including regulating cortisol, testosterone, vasopressin, and oxytocin hormones, modulating aggressive behavior. Animal studies have linked the morphology and function of the hypothalamus to aggression and affiliation, with a subregional pattern reflecting the functional division between the hypothalamic nuclei. We explored the relationship between hypothalamic subunit volumes in violent offenders with (PSY-V) and without (NPV) a psychotic disorder, and the association ...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 14, 2024 Category: Psychiatry Authors: Christina Bell Jaroslav Rokicki Natalia Tesli Tiril P Gurholt Gabriela Hjell Thomas Fischer-Vieler Nina Bang Ingrid Melle Ingrid Agartz Ole A Andreassen Petter Andreas Ringen Kirsten Rasmussen Hilde Dahl Christine Friestad Unn K Haukvik Source Type: research

Hypothalamic subunit volumes and relations to violence and psychopathy in male offenders with or without a psychotic disorder
AbstractThe hypothalamus is key to body homeostasis, including regulating cortisol, testosterone, vasopressin, and oxytocin hormones, modulating aggressive behavior. Animal studies have linked the morphology and function of the hypothalamus to aggression and affiliation, with a subregional pattern reflecting the functional division between the hypothalamic nuclei. We explored the relationship between hypothalamic subunit volumes in violent offenders with (PSY-V) and without (NPV) a psychotic disorder, and the association with psychopathy traits. 3T MRI scans (n = 628, all male 18–70 years) were obtained from PSY-V,n...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 14, 2024 Category: Neuroscience Source Type: research

Long-term follow-up of brain regional changes and the association with cognitive impairment in quarantined COVID-19 survivors
CONCLUSIONS: Our findings indicate a subjective cognitive decline in quarantined COVID-19 survivors 15 months after discharge, which is associated with brain structural alterations in the left Heschl's gyrus. The observed elevation of inflammatory markers suggests a potential mechanism involving inflammation-induced neurogenesis. These results contribute to our understanding of the possible mechanisms underlying long-term neuropsychiatric consequences of COVID-19 and highlight the need for further research to develop targeted interventions.PMID:38319396 | DOI:10.1007/s00406-023-01741-4 (Source: European Archives of Psychia...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 6, 2024 Category: Psychiatry Authors: Simai Zhang Minlan Yuan Danmei He Wen Dang Wei Zhang Source Type: research

Assessment of immunoprecipitation with subsequent immunoassays for the blood-based diagnosis of Alzheimer ’s disease
AbstractThe A β42/40 ratio and the concentration of phosphorylated Tau181 in blood plasma represent attractive biomarkers for Alzheimer's disease. As a means for reducing potential matrix effects, which may interfere with plasma immunoassays, we have previously developed a pre-analytical sample workup by semi-au tomated immunoprecipitation. Here we test the compatibility of pre-analytical immunoprecipitations with automated Aβ1-40, Aβ1-42 and phosphorylated Tau181 immunoassays on the Lumipulse platform and compare the diagnostic performance of the respective immunoprecipitation immunoassay approaches with direct plasma ...
Source: European Archives of Psychiatry and Clinical Neuroscience - February 6, 2024 Category: Neuroscience Source Type: research

Long-term follow-up of brain regional changes and the association with cognitive impairment in quarantined COVID-19 survivors
ConclusionsOur findings indicate a subjective cognitive decline in quarantined COVID-19 survivors 15 months after discharge, which is associated with brain structural alterations in the left Heschl's gyrus. The observed elevation of inflammatory markers suggests a potential mechanism involving inflammation-induced neurogenesis. These results contribute to our understanding of the possible mechani sms underlying long-term neuropsychiatric consequences of COVID-19 and highlight the need for further research to develop targeted interventions. (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - February 6, 2024 Category: Neuroscience Source Type: research