European Archives of Psychiatry and Clinical Neuroscience This is an RSS file. You can use it to subscribe to this data in your favourite RSS reader or to display this data on your own website or blog.

Beneficial and adverse effects of ketamine and its enantiomers, and the underlying mechanisms of ECT and rTMS efficacy
(Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - April 12, 2024 Category: Neuroscience Source Type: research

Diminished differentiation of rewards in individuals at clinical high-risk for psychosis
Eur Arch Psychiatry Clin Neurosci. 2024 Apr 10. doi: 10.1007/s00406-024-01794-z. Online ahead of print.ABSTRACTReward processing is impaired in people with schizophrenia, which may begin in the clinical high-risk (CHR) for psychosis period. The Monetary Incentive Delay (MID) task has been important in understanding the neural correlates of reward processing deficits in various psychiatric disorders. Previous research has found that CHR individuals have an imprecise mental representation of rewards, which leads to a diminished differentiation between rewards, though this has not been observed behaviorally. A total of 19 CHR...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 10, 2024 Category: Psychiatry Authors: D N Pratt M T Treadway G P Strauss V A Mittal Source Type: research

Diminished differentiation of rewards in individuals at clinical high-risk for psychosis
AbstractReward processing is impaired in people with schizophrenia, which may begin in the clinical high-risk (CHR) for psychosis period. The Monetary Incentive Delay (MID) task has been important in understanding the neural correlates of reward processing deficits in various psychiatric disorders. Previous research has found that CHR individuals have an imprecise mental representation of rewards, which leads to a diminished differentiation between rewards, though this has not been observed behaviorally. A total of 19 CHR individuals and 20 controls were given a novel variant of the MID task, designed to examine how modula...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 10, 2024 Category: Neuroscience Source Type: research

Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic
In this study, we investigate whether polygenic scores (PGSs) for mental health-related traits can distinguish between four resilience-vulnerability trajectories identified during the COVID-19 pandemic and associated lockdowns in 2020/21. We used multinomial regression in a genotyped subsample (n = 1316) of the CovSocial project. The most resilient trajectory characterized by the lowest mental health burden and the highest recovery rates served as the reference group. Compared to this most resilient trajectory, a higher value on the PGS for the well-being spectrum decreased the odds for individuals to be in one of the more...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 8, 2024 Category: Psychiatry Authors: Alicia M Schowe Malvika Godara Darina Czamara Mazda Adli Tania Singer Elisabeth B Binder Source Type: research

Genetic predisposition for negative affect predicts mental health burden during the COVID-19 pandemic
In this study, we investigate whether polygenic scores (PGSs) for mental health-related traits can distinguish between four resilience-vulnerability trajectories identified during the COVID-19 pandemic and associated lockdowns in 2020/21. We used multinomial regression in a genotyped subsample (n = 1316) of the CovSocial project. The most resilient trajectory characterized by the lowest mental health burden and the highest recovery rates served as the reference group. Compared to this most resilient trajectory, a higher value on the PGS for the well-being spectrum decreased the odds for individuals to be in one of the ...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 8, 2024 Category: Neuroscience Source Type: research

Effects of an integrative multimodal inpatient program on fatigue and work ability in patients with Post-COVID Syndrome-a prospective observational study
Eur Arch Psychiatry Clin Neurosci. 2024 Apr 5. doi: 10.1007/s00406-024-01792-1. Online ahead of print.ABSTRACTPost-COVID syndrome (PCS) is characterized by a variety of non-specific symptoms. One of the leading symptoms is fatigue. So far, there is no evidence-based causal therapy established and treatment of PCS is primarily symptom-oriented. The Clinic for Internal and Integrative Medicine in Bamberg, Germany, offers a comprehensive multimodal integrative inpatient therapy for PCS patients. Within a prospective uncontrolled observational study, the results of N = 79 patients were analysed. Post-COVID fatigue patients wer...
Source: European Archives of Psychiatry and Clinical Neuroscience - April 5, 2024 Category: Psychiatry Authors: Sarah Schmid Christine Uecker Antje Fr öhlich Jost Langhorst Source Type: research

Change in brain activation after transcranial pulsed electromagnetic fields in treatment-resistant depression
CONCLUSIONS: We found a decrease in reward-related activation as a result of tPEMF stimulation, while no effect of tPEMF on social-emotional processing was found. The treatment-related reduction in activation of regulatory regions may reflect normalization and may have implications for anhedonia. These findings suggest that there is an effect of tPEMF on brain activation of relevant circuits, albeit in the absence of a clinical antidepressant effect.PMID:38580858 | DOI:10.1007/s00406-024-01797-w (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - April 5, 2024 Category: Psychiatry Authors: Sjoerd M van Belkum Esther M Opmeer Hanneke Geugies Marrit K de Boer Robert A Schoevers Andr é Aleman Source Type: research