European Archives of Psychiatry and Clinical Neuroscience
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Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case-control study
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01632-8. Online ahead of print.ABSTRACTImpaired response inhibition is commonly present in individuals with attention-deficit/hyperactivity disorder (ADHD) and their unaffected relatives, suggesting impaired response inhibition as a candidate endophenotype in ADHD. Therefore, we explored whether behavioral and neural correlates of response inhibition are related to polygenic risk scores for ADHD (PRS-ADHD). We obtained functional magnetic resonance imaging of neural activity and behavioral measures during a stop-signal task in the NeuroIMAGE cohort, wh...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: G ülhan Saraçaydın I Hyun Ruisch Daan van Rooij Emma Sprooten Barbara Franke Jan K Buitelaar Andrea Dietrich Pieter J Hoekstra Source Type: research
Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01641-7. Online ahead of print.ABSTRACTThe Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients' insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet's agreement ...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: Paola Bucci Armida Mucci Giulia M Giordano Edoardo Caporusso Luigi Giuliani Dino Gibertoni Alessandro Rossi Paola Rocca Alessandro Bertolino Silvana Galderisi on the behalf of the Italian Network for Research on Psychoses Source Type: research
Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case-control study
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01632-8. Online ahead of print.ABSTRACTImpaired response inhibition is commonly present in individuals with attention-deficit/hyperactivity disorder (ADHD) and their unaffected relatives, suggesting impaired response inhibition as a candidate endophenotype in ADHD. Therefore, we explored whether behavioral and neural correlates of response inhibition are related to polygenic risk scores for ADHD (PRS-ADHD). We obtained functional magnetic resonance imaging of neural activity and behavioral measures during a stop-signal task in the NeuroIMAGE cohort, wh...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: G ülhan Saraçaydın I Hyun Ruisch Daan van Rooij Emma Sprooten Barbara Franke Jan K Buitelaar Andrea Dietrich Pieter J Hoekstra Source Type: research
Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01641-7. Online ahead of print.ABSTRACTThe Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients' insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet's agreement ...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: Paola Bucci Armida Mucci Giulia M Giordano Edoardo Caporusso Luigi Giuliani Dino Gibertoni Alessandro Rossi Paola Rocca Alessandro Bertolino Silvana Galderisi on the behalf of the Italian Network for Research on Psychoses Source Type: research
Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case-control study
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01632-8. Online ahead of print.ABSTRACTImpaired response inhibition is commonly present in individuals with attention-deficit/hyperactivity disorder (ADHD) and their unaffected relatives, suggesting impaired response inhibition as a candidate endophenotype in ADHD. Therefore, we explored whether behavioral and neural correlates of response inhibition are related to polygenic risk scores for ADHD (PRS-ADHD). We obtained functional magnetic resonance imaging of neural activity and behavioral measures during a stop-signal task in the NeuroIMAGE cohort, wh...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: G ülhan Saraçaydın I Hyun Ruisch Daan van Rooij Emma Sprooten Barbara Franke Jan K Buitelaar Andrea Dietrich Pieter J Hoekstra Source Type: research
Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 28. doi: 10.1007/s00406-023-01641-7. Online ahead of print.ABSTRACTThe Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients' insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet's agreement ...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Psychiatry Authors: Paola Bucci Armida Mucci Giulia M Giordano Edoardo Caporusso Luigi Giuliani Dino Gibertoni Alessandro Rossi Paola Rocca Alessandro Bertolino Silvana Galderisi on the behalf of the Italian Network for Research on Psychoses Source Type: research
Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case –control study
AbstractImpaired response inhibition is commonly present in individuals with attention-deficit/hyperactivity disorder (ADHD) and their unaffected relatives, suggesting impaired response inhibition as a candidate endophenotype in ADHD. Therefore, we explored whether behavioral and neural correlates of response inhibition are related to polygenic risk scores for ADHD (PRS-ADHD). We obtained functional magnetic resonance imaging of neural activity and behavioral measures during a stop-signal task in the NeuroIMAGE cohort, where inattention and hyperactivity-impulsivity symptoms were assessed with the Conners Parent Rating Sca...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Neuroscience Source Type: research
Insight in cognitive impairment assessed with the Cognitive Assessment Interview in a large sample of patients with schizophrenia
AbstractThe Cognitive Assessment Interview (CAI) is an interview-based scale measuring cognitive impairment and its impact on functioning in subjects with schizophrenia (SCZ). The present study aimed at assessing, in a large sample of SCZ (n = 601), the agreement between patients and their informants on CAI ratings, to explore patients’ insight in their cognitive deficits and its relationships with clinical and functional indices. Agreement between patient- and informant-based ratings was assessed by the Gwet’s agreement coeffi cient. Predictors of insight in cognitive deficits were explored by stepwise multiple re...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Neuroscience Source Type: research
Shared genetic etiology between ADHD, task-related behavioral measures and brain activation during response inhibition in a youth ADHD case –control study
AbstractImpaired response inhibition is commonly present in individuals with attention-deficit/hyperactivity disorder (ADHD) and their unaffected relatives, suggesting impaired response inhibition as a candidate endophenotype in ADHD. Therefore, we explored whether behavioral and neural correlates of response inhibition are related to polygenic risk scores for ADHD (PRS-ADHD). We obtained functional magnetic resonance imaging of neural activity and behavioral measures during a stop-signal task in the NeuroIMAGE cohort, where inattention and hyperactivity-impulsivity symptoms were assessed with the Conners Parent Rating Sca...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 28, 2023 Category: Neuroscience Source Type: research
Stress and reward in the maternal brain of mothers with borderline personality disorder: a script-based fMRI study
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 24. doi: 10.1007/s00406-023-01634-6. Online ahead of print.ABSTRACTBorderline personality disorder (BPD) is associated with altered neural activity in regions of salience and emotion regulation. An exaggerated sensitization to emotionally salient situations, increased experience of emotions, and dysfunctional regulative abilities could be reasons for increased distress also during parenting. Mothers with BPD tend to have less reciprocal mother-child interactions (MCI) and reveal altered cortisol and oxytocin reactivity in the interaction with their child, which could indicate alt...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 24, 2023 Category: Psychiatry Authors: Isabella Schneider Sabine C Herpertz Kai Ueltzh öffer Corinne Neukel Source Type: research
Stress and reward in the maternal brain of mothers with borderline personality disorder: a script-based fMRI study
AbstractBorderline personality disorder (BPD) is associated with altered neural activity in regions of salience and emotion regulation. An exaggerated sensitization to emotionally salient situations, increased experience of emotions, and dysfunctional regulative abilities could be reasons for increased distress also during parenting. Mothers with BPD tend to have less reciprocal mother –child interactions (MCI) and reveal altered cortisol and oxytocin reactivity in the interaction with their child, which could indicate altered processing of stress and reward. Here, we studied underlying neural mechanisms of disrupted MCI...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 24, 2023 Category: Neuroscience Source Type: research