How personality functioning relates to psychological distress and behavioral attitudes during the Covid-19 pandemic
This study aimed to investigate the role of dimensional aspects of personality during the Covid-19 pandemic. Specifically, we examined how personality functioning, defense mechanisms, and narcissism were related to psychological distress and cognitive and behavioral attitudes towards the rules of social distancing. In a non-clinical sample (N  = 254), Level of Personality Functioning Scale, Inventory of Personality Organization, Defense Style Questionnaire, Pathological Narcissism Inventory, and three single questions regarding emotional distress and behavioral attitudes towards the pandemic were used. Structural equat...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 6, 2024 Category: Neuroscience Source Type: research

Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review
Eur Arch Psychiatry Clin Neurosci. 2024 Jan 3. doi: 10.1007/s00406-023-01734-3. Online ahead of print.ABSTRACTPost-acute sequelae of COVID-19 can present as multi-organ pathology, with neuropsychiatric symptoms being the most common symptom complex, characterizing long COVID as a syndrome with a significant disease burden for affected individuals. Several typical symptoms of long COVID, such as fatigue, depressive symptoms and cognitive impairment, are also key features of other psychiatric disorders such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and major depressive disorder (MDD). However, clinically...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 3, 2024 Category: Psychiatry Authors: Dario Lucas Helbing Eva-Maria Dommaschk Lena Vera Danyeli Edgars Liepinsh Alexander Refisch Z ümrüt Duygu Sen Liga Zvejniece Tonia Rockt äschel Leonie Karoline Stabenow Helgi B Schi öth Martin Walter Maija Dambrova Bianca Besteher Source Type: research

Conceptual foundations of acetylcarnitine supplementation in neuropsychiatric long COVID syndrome: a narrative review
AbstractPost-acute sequelae of COVID-19 can present as multi-organ pathology, with neuropsychiatric symptoms being the most common symptom complex, characterizing long COVID as a syndrome with a significant disease burden for affected individuals. Several typical symptoms of long COVID, such as fatigue, depressive symptoms and cognitive impairment, are also key features of other psychiatric disorders such as myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) and major depressive disorder (MDD). However, clinically successful treatment strategies are still lacking and are often inspired by treatment options for dis...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 3, 2024 Category: Neuroscience Source Type: research

Vaccination and clozapine use: a systematic review and an analysis of the VAERS database
Eur Arch Psychiatry Clin Neurosci. 2024 Jan 2. doi: 10.1007/s00406-023-01729-0. Online ahead of print.ABSTRACTIn the context of COVID-19 concerns related to the potential interactions between clozapine and vaccination arose. With the ultimate goal of deriving recommendations for clinical practice, we systematically reviewed the current evidence regarding altered vaccine effectiveness in clozapine-treated patients and safety aspects of vaccination, such as haematological changes and the impact of vaccines on clozapine blood levels, in clozapine-treated patients. A systematic PRISMA-conform literature search of four database...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 2, 2024 Category: Psychiatry Authors: Aslihan Aksar Justina Lutz Elias Wagner Wolfgang Strube Jurjen J Luykx Alkomiet Hasan Source Type: research

Vaccination and clozapine use: a systematic review and an analysis of the VAERS database
AbstractIn the context of COVID-19 concerns related to the potential interactions between clozapine and vaccination arose. With the ultimate goal of deriving recommendations for clinical practice, we systematically reviewed the current evidence regarding altered vaccine effectiveness in clozapine-treated patients and safety aspects of vaccination, such as haematological changes and the impact of vaccines on clozapine blood levels, in clozapine-treated patients. A systematic PRISMA-conform literature search of four databases (PubMed, PsycINFO, EMBASE and Cochrane Library) complemented by a case-by-case analysis of the Vacci...
Source: European Archives of Psychiatry and Clinical Neuroscience - January 2, 2024 Category: Neuroscience Source Type: research

How to embrace transdiagnostic concepts when neurodevelopmental disorders become harbingers of adult psychopathology?
Eur Arch Psychiatry Clin Neurosci. 2023 Dec 27. doi: 10.1007/s00406-023-01756-x. Online ahead of print.NO ABSTRACTPMID:38150095 | DOI:10.1007/s00406-023-01756-x (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - December 27, 2023 Category: Psychiatry Authors: Sebastian Walther Source Type: research