European Archives of Psychiatry and Clinical Neuroscience
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Small area variations in non-affective first-episode psychosis: the role of socioeconomic and environmental factors
DiscussionIncreased rates of unemployment, the migrant population, and consumption of anxiolytics and antidepressants showed significant associations linked to the spatial-geographic incidence of NA-FEP. These results may allow targeting geographical areas to provide preventive interventions that potentially address modifiable environmental risk factors for NA-FEP. Further investigation is needed to understand the mechanisms underlying the associations between environmental risk factors and the incidence of NA-FEP. (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - August 23, 2023 Category: Neuroscience Source Type: research
Brain mechanisms for processing caress-like touch in skin-picking disorder
This study was preregistered on the German Clinical Trials Register (DRKS00022123, June 8th, 2020). (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - August 23, 2023 Category: Neuroscience Source Type: research
Multilayer depressive symptom networks in adults with bodily pain living in precarious housing or homelessness
AbstractHousing insecurity is associated with co-occurring depression and pain interfering with daily activities. Network analysis of depressive symptoms along with associated risk or protective exposures may identify potential targets for intervention in patients with co-occurring bodily pain. In a community-based sample of adults (n = 408) living in precarious housing or homelessness in Vancouver, Canada, depressive symptoms were measured by the Beck Depression Inventory; bodily pain and impact were assessed with the 36-item Short Form Health Survey. Network and bootstrap permutation analyses were used to compare dep...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 23, 2023 Category: Neuroscience Source Type: research
Identifying subgroups with differential response to CBASP versus Escitalopram during the first eight weeks of treatment in outpatients with persistent depressive disorder
This study identifies and characterizes subgroups of patients with PDD who are likely to benefit more from an acute treatment with psychotherapy than from pharmacotherapy and vice versa. Non-medicated outpatients with PDD were randomized to eight weeks of acute treatment with the Cognitive Behavioral Analysis System of Psychotherapy (CBASP; n = 29) or escitalopram plus clinical management (ESC/CM; n = 31). We combined several baseline variables to one composite moderator and identified two subgroups of patients: for 56.0%, ESC/CM was associated with a greater reduction in depression severity than CBASP, for the remaining 4...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 22, 2023 Category: Psychiatry Authors: Ilinca Serbanescu Elisabeth Schramm Henrik Walter Knut Schnell Ingo Zobel Sarah Drost Thomas Fangmeier Claus Normann Dieter Schoepf Source Type: research
Identifying subgroups with differential response to CBASP versus Escitalopram during the first eight weeks of treatment in outpatients with persistent depressive disorder
This study identifies and characterizes subgroups of patients with PDD who are likely to benefit more from an acute treatment with psychotherapy than from pharmacotherapy and vice versa. Non-medicated outpatients with PDD were randomized to eight weeks of acute treatment with the Cognitive Behavioral Analysis System of Psychotherapy (CBASP; n = 29) or escitalopram plus clinical management (ESC/CM; n = 31). We combined several baseline variables to one composite moderator and identified two subgroups of patients: for 56.0%, ESC/CM was associated with a greater reduction in depression severity than CBASP, for the re...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 22, 2023 Category: Neuroscience Source Type: research
New treatment strategies for mental health
Eur Arch Psychiatry Clin Neurosci. 2023 Aug 21. doi: 10.1007/s00406-023-01682-y. Online ahead of print.NO ABSTRACTPMID:37603079 | DOI:10.1007/s00406-023-01682-y (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - August 21, 2023 Category: Psychiatry Authors: Kenji Hashimoto Andrea Schmitt Source Type: research
New treatment strategies for mental health
(Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - August 21, 2023 Category: Neuroscience Source Type: research
Emotional distress and dysregulation as treatment targets to reduce suicide in psychosis: a scoping review
Eur Arch Psychiatry Clin Neurosci. 2023 Aug 19. doi: 10.1007/s00406-023-01675-x. Online ahead of print.ABSTRACTThere is a pressing need for effective treatments that address the high rate of suicide observed among people with psychosis. In this scoping review we highlight two suicidogenic treatment targets that have been relatively neglected in people with psychotic disorders: emotional distress and emotion dysregulation. We review the research on these constructs in psychosis and their relationship to suicide in this population, and then make clinical recommendations based on research findings. Emotional distress and emot...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 19, 2023 Category: Psychiatry Authors: Peter Phalen David Kimhy David Jobes Melanie Bennett Source Type: research
Influence of noninvasive brain stimulation on connectivity and local activation: a combined tDCS and fMRI study
This study aims at examining the effect of anodal and cathodal tDCS over the left dorsolateral prefrontal cortex (DLPFC) in comparison with sham stimulation on resting-state connectivity as well as functional activation and working memory performance. We hypothesized perturbed fronto-parietal resting-state connectivity during stimulation and altered working memory performance combined with modified functional working memory-related activation. We applied tDCS with 1 mA for 21 min over the DLPFC inside an fMRI scanner. During stimulation, resting-state fMRI was acquired and task-dependent fMRI during working memory task per...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 19, 2023 Category: Psychiatry Authors: Luise Victoria Claa ß Annika Hedrich Janis Reinelt Bernhard Sehm Arno Villringer Florian Schlagenhauf Jakob Kaminski Source Type: research
Societal costs of personality disorders among treatment-seeking patients in Norway: the relative contribution of specific DSM-5 categories
Eur Arch Psychiatry Clin Neurosci. 2023 Aug 19. doi: 10.1007/s00406-023-01655-1. Online ahead of print.ABSTRACTPersonality disorders (PDs) are associated with high levels of societal costs, regardless of whether a single PD or a broad range of PDs have been studied. However, research on the relative contribution of specific PD-types on societal costs is limited. The aim of this study was to explore the possible contributions of the individual DSM-5 categories of PDs on the level of societal costs and its components (health service costs and productivity loss), while controlling for the impact of comorbid mental health and ...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 19, 2023 Category: Psychiatry Authors: C A Sveen G Pedersen D A Ulvestad K E Zahl T Wilberg E H Kvarstein Source Type: research
Emotional distress and dysregulation as treatment targets to reduce suicide in psychosis: a scoping review
Eur Arch Psychiatry Clin Neurosci. 2023 Aug 19. doi: 10.1007/s00406-023-01675-x. Online ahead of print.ABSTRACTThere is a pressing need for effective treatments that address the high rate of suicide observed among people with psychosis. In this scoping review we highlight two suicidogenic treatment targets that have been relatively neglected in people with psychotic disorders: emotional distress and emotion dysregulation. We review the research on these constructs in psychosis and their relationship to suicide in this population, and then make clinical recommendations based on research findings. Emotional distress and emot...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 19, 2023 Category: Psychiatry Authors: Peter Phalen David Kimhy David Jobes Melanie Bennett Source Type: research
Influence of noninvasive brain stimulation on connectivity and local activation: a combined tDCS and fMRI study
This study aims at examining the effect of anodal and cathodal tDCS over the left dorsolateral prefrontal cortex (DLPFC) in comparison with sham stimulation on resting-state connectivity as well as functional activation and working memory performance. We hypothesized perturbed fronto-parietal resting-state connectivity during stimulation and altered working memory performance combined with modified functional working memory-related activation. We applied tDCS with 1 mA for 21 min over the DLPFC inside an fMRI scanner. During stimulation, resting-state fMRI was acquired and task-dependent fMRI during working memory task per...
Source: European Archives of Psychiatry and Clinical Neuroscience - August 19, 2023 Category: Psychiatry Authors: Luise Victoria Claa ß Annika Hedrich Janis Reinelt Bernhard Sehm Arno Villringer Florian Schlagenhauf Jakob Kaminski Source Type: research