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Brain-heart interaction disruption in major depressive disorder: disturbed rhythm modulation of the cardiac cycle on brain transient theta bursts
This study aimed to provide direct evidence for brain-heart synchronization in temporal dynamics and clarify the mechanism of brain-heart interaction disruption in MDD. Eight-minute resting-state (closed eyes) electroencephalograph and electrocardiogram signals were acquired simultaneously. The Jaccard index (JI) was used to measure the temporal synchronization between cortical theta transient bursts and cardiac cycle activity (diastole and systole) in 90 MDD patients and 44 healthy controls (HCs) at rest. The deviation JI was used to reflect the equilibrium of brain activity between diastole and systole. The results showe...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2023 Category: Psychiatry Authors: Hongliang Zhou Tingting Xiong Zhongpeng Dai Haowen Zou Xvmiao Wang Hao Tang Yinghong Huang Hao Sun Wei You Zhijian Yao Qing Lu Source Type: research

Risk of autoimmune diseases after post-traumatic stress disorder: a nationwide cohort study
Eur Arch Psychiatry Clin Neurosci. 2023 Jun 15. doi: 10.1007/s00406-023-01639-1. Online ahead of print.ABSTRACTThis longitudinal study aimed to investigate the risk of subsequent autoimmune disease in patients with post-traumatic stress disorder (PTSD) in Asian population. Between 2002 and 2009, we enrolled 5273 patients with PTSD and 1:4 matched controls from the National Health Insurance Database of Taiwan, and followed up the patients until December 31, 2011, or death. The investigated autoimmune diseases included thyroiditis, lupus, rheumatic arthritis, inflammatory bowel disease, Sjogren's syndrome, dermatomyositis, a...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2023 Category: Psychiatry Authors: Tien-Wei Hsu Ya-Mei Bai Shih-Jen Tsai Tzeng-Ji Chen Mu-Hong Chen Chih-Sung Liang Source Type: research

Brain –heart interaction disruption in major depressive disorder: disturbed rhythm modulation of the cardiac cycle on brain transient theta bursts
This study aimed to provide direct evidence for brain–heart synchronization in temporal dynamics and clarify the mechanism of brain–heart interaction disruption in MDD. Eight-minute resting-state (closed eyes) electroencephalograph and electrocardiogram signals were acquired simultaneously. The Jaccard index (JI) was used to measure the temporal synchronization between cortical theta transient bursts and cardiac cycle activity (diastole and syst ole) in 90 MDD patients and 44 healthy controls (HCs) at rest. The deviation JI was used to reflect the equilibrium of brain activity between diastole and systole. The results ...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2023 Category: Neuroscience Source Type: research

Risk of autoimmune diseases after post-traumatic stress disorder: a nationwide cohort study
AbstractThis longitudinal study aimed to investigate the risk of subsequent autoimmune disease in patients with post-traumatic stress disorder (PTSD) in Asian population. Between 2002 and 2009, we enrolled 5273 patients with PTSD and 1:4 matched controls from the National Health Insurance Database of Taiwan, and followed up the patients until December 31, 2011, or death. The investigated autoimmune diseases included thyroiditis, lupus, rheumatic arthritis, inflammatory bowel disease, Sjogren ’s syndrome, dermatomyositis, and polymyositis. The Cox regression model was used to estimate the risk of developing autoimmune dis...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 15, 2023 Category: Neuroscience Source Type: research

Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism
In conclusion, plasma NFL level was increased in patients with AD and reduced after early abstinence. Reduction in NFL level corroborated well with the improvement of clinical symptoms. The ALDH2 rs671 polymorphism may play a role in modulating the extent of neuroaxonal injury and its recovery.PMID:37314537 | DOI:10.1007/s00406-023-01635-5 (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Psychiatry Authors: Ming-Chyi Huang Hsueh-Yuan Tu Ren-Hua Chung Hsiang-Wei Kuo Tung-Hsia Liu Che-Hong Chen Daria Mochly-Rosen Yu-Li Liu Source Type: research

Identifying clinical risk factors correlated with addictive features of non-suicidal self-injury among a consecutive psychiatric outpatient sample of adolescents and young adults
This study was conducted from April 2021 to May 2022. The mean age of participants was 15.93 (SD = 2.56) years with 418 females (76.3%), and the prevalence of addictive NSSI was 57.5% (n = 315). Subjects with addictive NSSI had a higher lifetime prevalence of nicotine and alcohol use, a higher prevalence of current internet addiction, suicidality, and alexithymia, and were more likely to have physical abuse/neglect, emotional abuse, and sexual abuse than NSSI subjects without addictive features. Among participants with NSSI, the strongest predictors of addictive features of NSSI were female (OR = 2.405, 95% CI 1.512-3.824,...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Psychiatry Authors: Wang Ying Yidong Shen Jianjun Ou Hui Chen Furong Jiang Fangru Yang Jianling Li Xiao Qian Wenfeng Luo Gang Wang Huixi Dong Source Type: research

Identifying clinical risk factors correlated with addictive features of non-suicidal self-injury among a consecutive psychiatric outpatient sample of adolescents and young adults
This study was conducted from April 2021 to May 2022. The mean age of participants was 15.93 (SD = 2.56) years with 418 females (76.3%), and the prevalence of addictive NSSI was 57.5% (n = 315). Subjects with addictive NSSI had a higher l ifetime prevalence of nicotine and alcohol use, a higher prevalence of current internet addiction, suicidality, and alexithymia, and were more likely to have physical abuse/neglect, emotional abuse, and sexual abuse than NSSI subjects without addictive features. Among participants with NSSI, the str ongest predictors of addictive features of NSSI were female (OR = 2.405, 95% C...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Neuroscience Source Type: research

Changes of neurofilament light chain in patients with alcohol dependence following withdrawal and the genetic effect from ALDH2 Polymorphism
In conclusion, plasma NFL level was increased in patients with AD and reduced after early abstinence. Reduction in NFL level corroborated well with the improvement of clinical symptoms. TheALDH2 rs671 polymorphism may play a role in modulating the extent of neuroaxonal injury and its recovery. (Source: European Archives of Psychiatry and Clinical Neuroscience)
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Neuroscience Source Type: research

Identifying clinical risk factors correlated with addictive features of non-suicidal self-injury among a consecutive psychiatric outpatient sample of adolescents and young adults
This study was conducted from April 2021 to May 2022. The mean age of participants was 15.93 (SD = 2.56) years with 418 females (76.3%), and the prevalence of addictive NSSI was 57.5% (n = 315). Subjects with addictive NSSI had a higher l ifetime prevalence of nicotine and alcohol use, a higher prevalence of current internet addiction, suicidality, and alexithymia, and were more likely to have physical abuse/neglect, emotional abuse, and sexual abuse than NSSI subjects without addictive features. Among participants with NSSI, the str ongest predictors of addictive features of NSSI were female (OR = 2.405, 95% C...
Source: European Archives of Psychiatry and Clinical Neuroscience - June 14, 2023 Category: Neuroscience Source Type: research