Deciphering the dynamics of methicillin-resistant Staphylococcus aureus biofilm formation: from molecular signaling to nanotherapeutic advances
Methicillin-resistant Staphylococcus aureus (MRSA) represents a global threat, necessitating the development of effective solutions to combat this emerging superbug. In response to selective pressures within heal... (Source: Cell Communication and Signaling)
Source: Cell Communication and Signaling - March 22, 2024 Category: Molecular Biology Authors: Nirmeen Aboelnaga, Salma W. Elsayed, Nehal Adel Abdelsalam, Salma Salem, Nehal A. Saif, Manar Elsayed, Shehab Ayman, Maha Nasr and Mohamed Elhadidy Tags: Review Source Type: research
Whole genome sequencing and molecular epidemiology of methicillin-resistant Staphylococcus aureus isolated from patients with bacteraemia in Slovenia
ConclusionThis study demonstrates that bacteraemia in central Slovenia is caused by diverse MRSA lineages. Identification of newly emerged lineages should be followed in the future to detect changes in the molecular epidemiology of MRSA in our country. (Source: European Journal of Clinical Microbiology and Infectious Diseases)
Source: European Journal of Clinical Microbiology and Infectious Diseases - March 22, 2024 Category: Microbiology Source Type: research
Simultaneous Dual ‐Gene Test of Methicillin‐Resistant Staphylococcus Aureus using an Argonaute‐Centered Portable and Visual Biosensor
The STAR platform is developed for simultaneous dual-gene test of methicillin-resistantStaphylococcus aureus using an Argonaute-centered portable biosensor. With the platform, the targeted nucleic acid signals gene are dexterously converted into fluorescent signals. A portable 3D-printed device that integrated functions of heating reaction and fluorescence detection is designed, showing the potential of PON for drug-resistant pathogenic bacteria and others. AbstractThe development of novel method for drug-resistant bacteria detection is imperative. A simultaneous dual-gene Test of methicillin-resistantStaphylococcus aureus...
Source: Small - March 20, 2024 Category: Nanotechnology Authors: Jun Kou,
Yaru Li,
Zhiying Zhao,
Jiali Qiao,
Qiang Zhang,
Xiao Han,
Xinkuan Cheng,
Shuli Man,
Long Ma Tags: Research Article Source Type: research
Analysis of carbapenem-resistant < em > Acinetobacter baumannii < /em > carbapenemase gene distribution and biofilm formation
CONCLUSION: The clinical strains have a high resistance rate to carbapenems, and the CRAB with blaOXA-51 and blaOXA-23 genes has a high resistance to antibiotics and a strong biofilm.PMID:38505565 | PMC:PMC10944714 (Source: International Journal of Molecular Epidemiology and Genetics)
Source: International Journal of Molecular Epidemiology and Genetics - March 20, 2024 Category: Genetics & Stem Cells Authors: Lin Wang Qi-Wei Chen Yan-Chun Qin Xue-Li Yi Hong Zeng Source Type: research
Waste to resource: Mining antimicrobial peptides in sludge from metagenomes using machine learning
Environ Int. 2024 Mar 11;186:108574. doi: 10.1016/j.envint.2024.108574. Online ahead of print.ABSTRACTThe emergence of antibiotic-resistant bacteria poses a huge threat to the treatment of infections. Antimicrobial peptides are a class of short peptides that widely exist in organisms and are considered as potential substitutes for traditional antibiotics. Here, we use metagenomics combined with machine learning to find antimicrobial peptides from environmental metagenomes and successfully obtained 16,044,909 predicted AMPs. We compared the abundance of potential antimicrobial peptides in natural environments and engineered...
Source: Environment International - March 20, 2024 Category: Environmental Health Authors: Jiaqi Xu Xin Xu Yunhan Jiang Yulong Fu Chaofeng Shen Source Type: research
Analysis of carbapenem-resistant < em > Acinetobacter baumannii < /em > carbapenemase gene distribution and biofilm formation
CONCLUSION: The clinical strains have a high resistance rate to carbapenems, and the CRAB with blaOXA-51 and blaOXA-23 genes has a high resistance to antibiotics and a strong biofilm.PMID:38505565 | PMC:PMC10944714 (Source: International Journal of Molecular Epidemiology and Genetics)
Source: International Journal of Molecular Epidemiology and Genetics - March 20, 2024 Category: Genetics & Stem Cells Authors: Lin Wang Qi-Wei Chen Yan-Chun Qin Xue-Li Yi Hong Zeng Source Type: research
Waste to resource: Mining antimicrobial peptides in sludge from metagenomes using machine learning
Environ Int. 2024 Mar 11;186:108574. doi: 10.1016/j.envint.2024.108574. Online ahead of print.ABSTRACTThe emergence of antibiotic-resistant bacteria poses a huge threat to the treatment of infections. Antimicrobial peptides are a class of short peptides that widely exist in organisms and are considered as potential substitutes for traditional antibiotics. Here, we use metagenomics combined with machine learning to find antimicrobial peptides from environmental metagenomes and successfully obtained 16,044,909 predicted AMPs. We compared the abundance of potential antimicrobial peptides in natural environments and engineered...
Source: Environment International - March 20, 2024 Category: Environmental Health Authors: Jiaqi Xu Xin Xu Yunhan Jiang Yulong Fu Chaofeng Shen Source Type: research
Analysis of carbapenem-resistant < em > Acinetobacter baumannii < /em > carbapenemase gene distribution and biofilm formation
CONCLUSION: The clinical strains have a high resistance rate to carbapenems, and the CRAB with blaOXA-51 and blaOXA-23 genes has a high resistance to antibiotics and a strong biofilm.PMID:38505565 | PMC:PMC10944714 (Source: International Journal of Molecular Epidemiology and Genetics)
Source: International Journal of Molecular Epidemiology and Genetics - March 20, 2024 Category: Genetics & Stem Cells Authors: Lin Wang Qi-Wei Chen Yan-Chun Qin Xue-Li Yi Hong Zeng Source Type: research
