Ultrasound-driven radical chain reaction and immunoregulation of piezoelectric-based hybrid coating for treating implant infection
Biomaterials. 2024 Mar 14;307:122532. doi: 10.1016/j.biomaterials.2024.122532. Online ahead of print.ABSTRACTThe poor efficiency of US-responsive coatings on implants restricts their practical application. Immunotherapy that stimulates immune cells to enhance their antibacterial activity is expected to synergize with sonodynamic therapy for treating implant infection effectively and safely. Herein, US-responsive hybrid coatings composed of the oxygen-deficient BaTiO3 nanorod arrays and l-arginine (BaTiO3-x/LA) are designed and prepared on titanium implants for sonocatalytic therapy-cooperated immunotherapy to treat Methici...
Source: Biomaterials - March 17, 2024 Category: Materials Science Authors: Menglin Sun Jiameng Wang Xiaobo Huang Ruiqiang Hang Peide Han Jiqiang Guo Xiaohong Yao Paul K Chu Xiangyu Zhang Source Type: research

Salinity-mediated enhancement of quaternary ammonium compounds resistance and removal in endophytic bacteria LSE01
In this study, different inorganic salts (NaCl, KCl, CaCl2, MgCl2) were used to induce endophytes LSE01 isolated from hyperaccumulating plants. After five generations of cultivation under 80 g/L NaCl, the minimum inhibitory concentration (MIC) of LSE01 to QACs increased by about 3-fold, while its degradation extent increased from 8% to 84% for C12BDMA-Cl and 5%-89% for C14BDMA-Cl. Transmission electron microscopy (TEM) and three-dimensional fluorescence spectra indicated that the cells induced by high concentration of salt caused plasmolysis and secreted more bound extracellular polymeric substances (B-EPS); these changes ...
Source: Environmental Research - March 17, 2024 Category: Environmental Health Authors: Xiao Xiao Junjie Li Xiaotong Wang Lin Ding Shengju Shen Ting Liu Zhong Ren Xubiao Luo Source Type: research

Effect of ciprofloxacin on the one-stage partial nitrification and anammox biofilm system: A multivariate analysis focusing on size-fractionated organic components
Chemosphere. 2024 Mar 15:141731. doi: 10.1016/j.chemosphere.2024.141731. Online ahead of print.ABSTRACTThe impact of ciprofloxacin (CIP) in the partial nitrification and anammox biofilm system was investigated by multivariate analysis, focusing on size-fractionated organic components. The CIP dose of 10 μg/L did not inhibit the total nitrogen (TN) removal efficiency, even though the abundance of antibiotic resistant genes (ARGs) (i.e., qnrD, qnrB, qnrA, qnrS, and arcA) was elevated. However, a gradual higher CIP dosing up to 100 μg/L inhibited the TN removal efficiency, while the abundance of ARGs was still increased. Mo...
Source: Chemosphere - March 17, 2024 Category: Chemistry Authors: Keke Xiao Gudrun Abbt-Braun Robert Pleitner Harald Horn Source Type: research

Effect of ciprofloxacin on the one-stage partial nitrification and anammox biofilm system: A multivariate analysis focusing on size-fractionated organic components
Chemosphere. 2024 Mar 15:141731. doi: 10.1016/j.chemosphere.2024.141731. Online ahead of print.ABSTRACTThe impact of ciprofloxacin (CIP) in the partial nitrification and anammox biofilm system was investigated by multivariate analysis, focusing on size-fractionated organic components. The CIP dose of 10 μg/L did not inhibit the total nitrogen (TN) removal efficiency, even though the abundance of antibiotic resistant genes (ARGs) (i.e., qnrD, qnrB, qnrA, qnrS, and arcA) was elevated. However, a gradual higher CIP dosing up to 100 μg/L inhibited the TN removal efficiency, while the abundance of ARGs was still increased. Mo...
Source: Chemosphere - March 17, 2024 Category: Chemistry Authors: Keke Xiao Gudrun Abbt-Braun Robert Pleitner Harald Horn Source Type: research

Ultrasound-driven radical chain reaction and immunoregulation of piezoelectric-based hybrid coating for treating implant infection
Biomaterials. 2024 Mar 14;307:122532. doi: 10.1016/j.biomaterials.2024.122532. Online ahead of print.ABSTRACTThe poor efficiency of US-responsive coatings on implants restricts their practical application. Immunotherapy that stimulates immune cells to enhance their antibacterial activity is expected to synergize with sonodynamic therapy for treating implant infection effectively and safely. Herein, US-responsive hybrid coatings composed of the oxygen-deficient BaTiO3 nanorod arrays and l-arginine (BaTiO3-x/LA) are designed and prepared on titanium implants for sonocatalytic therapy-cooperated immunotherapy to treat Methici...
Source: Biomaterials - March 17, 2024 Category: Materials Science Authors: Menglin Sun Jiameng Wang Xiaobo Huang Ruiqiang Hang Peide Han Jiqiang Guo Xiaohong Yao Paul K Chu Xiangyu Zhang Source Type: research