NovoSorb ® Biodegradable Temporizing Matrix: a novel approach for treatment of extremity avulsion injuries in children
ConclusionBTM is a promising alternative for reconstruction of complex trauma extremity wounds in children following avulsion injuries, even in cases of concomitant bone injuries. Interpretation may be limited by sample size. (Source: European Journal of Trauma and Emergency Surgery)
Source: European Journal of Trauma and Emergency Surgery - April 26, 2024 Category: Emergency Medicine Source Type: research

Pediatric Facial Burn Reconstruction
Semin Plast Surg DOI: 10.1055/s-0044-1786009Contrary to prior pediatric burn treatment philosophies, we now know that early burn excision and grafting for non life-threatening burns can compromise future reconstruction. Extensive scar excision should be minimized and scar rehabilitation maximized, as secondary iatrogenic deformities can become even more difficult to fix. Scar remodeling with local tissue rearrangement can relieve tension and soften scars over time. The majority of facial burns often only involve skin and can be adequately treated without the need for complex flap reconstruction. Facial burn scars are a dif...
Source: Seminars in Plastic Surgery - April 26, 2024 Category: Cosmetic Surgery Authors: Moon, Tina Driscoll, Daniel N. Tags: Review Article Source Type: research

Correction of Congenital Syndactyly of the Hand with Minimal Full-Thickness Skin Graft from the Weight-Bearing Midline Plantar Area
CONCLUSION: Correction of congenital hand syndactyly using midline plantar FTSG from the weight-bearing area can reduce scarring on the hand dorsum, ensure superior color similarity with surrounding skin, and offer inconspicuous donor sites compared to no-skin-graft or groin FTSG techniques.PMID:38652871 | DOI:10.1097/PRS.0000000000011484 (Source: Hand Surgery)
Source: Hand Surgery - April 23, 2024 Category: Surgery Authors: Soo Jin Woo Kwang Hyun Park Sang Hyun Woo Hyun Jae Nam Source Type: research

Correction of Congenital Syndactyly of the Hand with Minimal Full-Thickness Skin Graft from the Weight-Bearing Midline Plantar Area
CONCLUSION: Correction of congenital hand syndactyly using midline plantar FTSG from the weight-bearing area can reduce scarring on the hand dorsum, ensure superior color similarity with surrounding skin, and offer inconspicuous donor sites compared to no-skin-graft or groin FTSG techniques.PMID:38652871 | DOI:10.1097/PRS.0000000000011484 (Source: Hand Surgery)
Source: Hand Surgery - April 23, 2024 Category: Surgery Authors: Soo Jin Woo Kwang Hyun Park Sang Hyun Woo Hyun Jae Nam Source Type: research

The application of umbilical cord blood-derived platelet gel for skin ulcers associated with chronic graft-versus-host disease in pediatrics: A randomized trial
Hematopoietic stem cell transplantation (HSCT) is a definitive therapy for a myriad of malignant and non-malignant hematopoietic, immune-related, and lysosomal storage disorders1, 2. However, graft-versus-host disease (GVHD), the main complication of allogeneic HSCT (allo-HSCT), significantly compromises the survival and the quality of life of recipients3-5. Accordingly, chronic GVHD (cGVHD) afflicts 20-50% of allo-HSCT cases6 and is one of the principal etiologies of morbidity and compromised quality of life, especially among pediatric patients7, 8. (Source: Biology of Blood and Marrow Transplantation)
Source: Biology of Blood and Marrow Transplantation - April 23, 2024 Category: Hematology Authors: Rashin Mohseni, Pouya Mahdavi Sharif, Abbas Khosravi, Ahmad Reza Taheri, Maryam Behfar, Morteza Zarrabi, Leila Jafari, Fahimeh Jafari, Zeynab Nikfetrat, Parisa Naji, Amir Ali Hamidieh Source Type: research

The interpositional bypass with a parietal branch of superficial temporal artery graft for symptomatic atherosclerotic anterior cerebral artery stenosis or occlusion
CONCLUSION: The results of this study indicate that PISAB, as a safe superficial bypass, can effectively reduce the risk of stroke in SAASO patients. More precise conclusions will require randomized control studies.PMID:38645741 | PMC:PMC11026711 | DOI:10.3389/fneur.2024.1361151 (Source: Atherosclerosis)
Source: Atherosclerosis - April 22, 2024 Category: Cardiology Authors: Chuyang Tai Cong Ling Tengchao Huang Baoyu Zhang Yang Yang Lei Wei Haiwan Wu Ni Mo Hui Wang Chuan Chen Source Type: research

Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis
CONCLUSION: Fish skin grafts have been shown to be more effective for achieving complete ulcer healing compared to current conventional treatments in diabetic foot disease.PMID:38644082 | DOI:10.1016/j.pcd.2024.03.008 (Source: Primary Care)
Source: Primary Care - April 21, 2024 Category: Primary Care Authors: Maria Ruiz-Mu ñoz Francisco-Javier Martinez-Barrios Pablo Cervera-Garvi Eva Lopezosa-Reca Ana J Marchena-Rodriguez Source Type: research

Fish skin grafts versus standard of care on wound healing of chronic diabetic foot ulcers: A systematic review and meta-analysis
This study will explore the effectiveness of fish skin grafts (FSG) in ulcer healing in diabetic foot disease compared to standard of care (SOC). (Source: Primary Care Diabetes)
Source: Primary Care Diabetes - April 21, 2024 Category: Primary Care Authors: Maria Ruiz-Mu ñoz, Francisco-Javier Martinez-Barrios, Pablo Cervera-Garvi, Eva Lopezosa-Reca, Ana J. Marchena-Rodriguez Source Type: research

Cellular therapeutics and immunotherapies in wound healing - on the pulse of time?
Mil Med Res. 2024 Apr 18;11(1):23. doi: 10.1186/s40779-024-00528-5.ABSTRACTChronic, non-healing wounds represent a significant challenge for healthcare systems worldwide, often requiring significant human and financial resources. Chronic wounds arise from the complex interplay of underlying comorbidities, such as diabetes or vascular diseases, lifestyle factors, and genetic risk profiles which may predispose extremities to local ischemia. Injuries are further exacerbated by bacterial colonization and the formation of biofilms. Infection, consequently, perpetuates a chronic inflammatory microenvironment, preventing the prog...
Source: Cell Research - April 18, 2024 Category: Cytology Authors: Lioba Huelsboemer Leonard Knoedler Alejandro Kochen Catherine T Yu Helia Hosseini Katharina S Hollmann Ashley E Choi Viola A St ögner Samuel Knoedler Henry C Hsia Bohdan Pomahac Martin Kauke-Navarro Source Type: research

Cellular therapeutics and immunotherapies in wound healing – on the pulse of time?
AbstractChronic, non-healing wounds represent a significant challenge for healthcare systems worldwide, often requiring significant human and financial resources. Chronic wounds arise from the complex interplay of underlying comorbidities, such as diabetes or vascular diseases, lifestyle factors, and genetic risk profiles which may predispose extremities to local ischemia. Injuries are further exacerbated by bacterial colonization and the formation of biofilms. Infection, consequently, perpetuates a chronic inflammatory microenvironment, preventing the progression and completion of normal wound healing. The current standar...
Source: Military Medical Research - April 18, 2024 Category: International Medicine & Public Health Source Type: research

A prospective analysis of the efficacy of phase II autologous skin grafting on deep second ‑degree burns on the dorsum of the hand
Exp Ther Med. 2024 Mar 27;27(5):238. doi: 10.3892/etm.2024.12526. eCollection 2024 May.ABSTRACTThe aim of the present study was to investigate the possibility of reducing the damage to the donor site while preserving the functional recovery of the dorsum of the hand following burn injury. An attempt was made to analyze the effect of a phased surgery approach on inflammatory indicators. A two-phase treatment was administered on a total of 64 patients with deep second-degree burns on the dorsum of the hand who were admitted to Guangzhou Red Cross Hospital between January 2020 and March 2023. During phase I treatment, the wou...
Source: Experimental and Therapeutic Medicine - April 17, 2024 Category: General Medicine Authors: Jing'en Sun Siman Su Songsong Jiao Gang Li Zhi Zhang Weihua Lin Shuyao Zhang Source Type: research