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Severe Liver Dysfunction after Donor Lymphocyte Infusion for Relapsed Multiple Myeloma
Korean J Gastroenterol. 2024 Mar 25;83(3):123-126. doi: 10.4166/kjg.2024.007.ABSTRACTDonor lymphocyte infusion (DLI) is performed to augment an anti-tumor immune response or ensure donor stem cells remain engrafted following allogeneic stem cell transplantation but may induce graft-versus-host disease (GVHD) involving skin, intestine, and liver. Although hepatic involvement of GVHD can manifest as mild to severe hepatitis, few reports have mentioned acute severe liver dysfunction with encephalopathy. We experienced a case of acute severe liver dysfunction with semicoma after DLI in a patient with relapsed multiple myeloma ...
Source: Korean J Gastroenter... - March 24, 2024 Category: Gastroenterology Authors: Tae-Hoon No Nae-Yun Heo Seung Ha Park Joon Hyuk Choi Junghwan Lee Sung Nam Lim Seon Yang Park Source Type: research

Infected femoral artery pseudoaneurysm ligation and revascularisation: A case report
Key Clinical MessageAlthough ligating femoral pseudoaneurysm is a safe procedure, some cases require revascularization, and the appropriate treatment should be tailored to the patient.AbstractIn this case report, we highlight the challenge in treating infected femoral artery pseudoaneurysm. The patient, a 37-year-old male intravenous drug abuser, presented to the emergency department with a 2-month history of a progressively growing lump over his right groin. Two days before the presentation the swelling became hot and painful. After physical examination, it was revealed that the localized swelling is about 15 × 15�...
Source: Clinical Case Reports - March 22, 2024 Category: General Medicine Authors: Mohammed Alsagheer Alhewy, Ehab Abd Elmoneim Ghazala, Hassan Gado, Wael Abdo Abdo Abd ‐Elgawad, Ahmed Atef Khamis Tags: CASE REPORT Source Type: research

Biomechanical analysis of the human derived soft tissue graft Epiflex for use in oral soft tissue augmentation
This study aimed to investigate the biomechanical properties, cell migration, and revascularization of the acellular dermal matrix Epiflex. As a decellularized, freeze –dried human skin graft, Epiflex has broad... (Source: International Journal of Implant Dentistry)
Source: International Journal of Implant Dentistry - March 22, 2024 Category: Dentistry Authors: Keyvan Sagheb, Robert Noelken, Saskia-Vanessa Schr öger, Christian Walter, Julian Jakob Graef and Sven Schumann Tags: Research Source Type: research

Rescue Aortoiliac Subintimal Recanalization and Stent “Endobypass” for Leriche Syndrome Complicated by Fournier Gangrene
A 67-year-old woman with longstanding Rutherford 4 leg and buttock claudication secondary to aortobiiliac occlusion (Leriche syndrome) presented with Fournier gangrene. Emergent life-saving debridement was complicated by a large nonhealing wound requiring 7 surgeries over 6 weeks. Muscle flap and skin graft surgeries failed because of poor perfusion owing to calcified aortobiiliac chronic total occlusion (CTO) (Fig 1a). She was not a candidate for surgical bypass and refused hospice care. She underwent aortoiliac recanalization to provide pelvic wall perfusion to allow for future skin and muscle grafts. (Source: Journal of...
Source: Journal of Vascular and Interventional Radiology : JVIR - March 21, 2024 Category: Radiology Authors: Raj Pyne Tags: Extreme IR Source Type: research

Endoscopic mastectomy followed by immediate breast reconstruction with fat grafting for breast cancer
CONCLUSION: To the best of our knowledge, this is the first report of endoscopic mastectomy with immediate FG for reconstruction. When compared with other immediate autologous reconstructions, our strategy could minimize the skin incision and procedure duration, as well as limit complications. Further prospective investigations are needed to evaluate oncological safety, surgical outcomes, and patient satisfaction.PMID:38512534 | DOI:10.1007/s12282-024-01561-x (Source: Breast Cancer)
Source: Breast Cancer - March 21, 2024 Category: Cancer & Oncology Authors: Kazutaka Narui Toshihiko Satake Takashi Ishikawa Mayu Muto Yui Tsunoda Akimitsu Yamada Kei Kawashima Natsuki Uenaka Yoshie Fujiwara Masanori Oshi Shoko Adachi Chiho Suzuki Tomoko Wada Shinya Yamamoto Mikiko Tanabe Jiro Maegawa Itaru Endo Source Type: research

Intercalary Resection of the Tibia for Primary Bone Tumors: Are Vascularized Fibula Autografts With or Without Allografts a Durable Reconstruction?
CONCLUSION: VFG, alone or combined with an allograft, could be considered in reconstructing a lower extremity after intercalary resections of the tibia for primary bone tumors, and it avoids the use of a large endoprosthesis. However, this procedure was associated with frequent, often severe complications during the first postoperative years and complication-free survival of 58% at 5 years. Nearly 10% of patients ultimately had an amputation. For patients whose reconstruction succeeded, the technique provides a durable reconstruction with good MSTS scores, and we believe it is useful for active patients with long life expe...
Source: Cell Research - March 21, 2024 Category: Cytology Authors: Domenico Andrea Campanacci Roberto Scanferla Mariagrazia Marsico Federico Scolari Guido Scoccianti Giovanni Beltrami Luca Delcroix Marco Innocenti Rodolfo Capanna Source Type: research

Intercalary Resection of the Tibia for Primary Bone Tumors: Are Vascularized Fibula Autografts With or Without Allografts a Durable Reconstruction?
CONCLUSION: VFG, alone or combined with an allograft, could be considered in reconstructing a lower extremity after intercalary resections of the tibia for primary bone tumors, and it avoids the use of a large endoprosthesis. However, this procedure was associated with frequent, often severe complications during the first postoperative years and complication-free survival of 58% at 5 years. Nearly 10% of patients ultimately had an amputation. For patients whose reconstruction succeeded, the technique provides a durable reconstruction with good MSTS scores, and we believe it is useful for active patients with long life expe...
Source: Clinical Orthopaedics and Related Research - March 21, 2024 Category: Orthopaedics Authors: Domenico Andrea Campanacci Roberto Scanferla Mariagrazia Marsico Federico Scolari Guido Scoccianti Giovanni Beltrami Luca Delcroix Marco Innocenti Rodolfo Capanna Source Type: research