[Relief of Obstruction in the Management of Pancreatic Cancer].
Abstract Pancreatic cancer is a major cause of cancer-related mortality and morbidity, and its incidence is increasing as the population is aging. On the other hand, significant improvement in the prognosis has not occurred. The absence of early diagnosis means that many patients are diagnosed only when they develop symptoms, such as jaundice, due to a biliary obstruction. The role of endoscopy in multidisciplinary care for patients with pancreatic cancer continues to evolve. Controversy remains regarding the best preoperative biliary drainage in patients with surgically resectable pancreatic head cancer. In gener...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Kwon CI Tags: Korean J Gastroenterol Source Type: research

[Relief of Cancer Pain in Patients with Pancreatic Cancer].
Abstract Pancreatic cancer is a dismal disease with a poor prognosis and is one of the most painful malignancies. Therefore, adequate pain control is essential to improving the patient's quality of life. Pain in pancreatic cancer has complex pathophysiologic mechanisms and different characteristics. The choice of pain management modalities should be individualized depending on the pain characteristics using a multidisciplinary approach. The treatment options available include medical treatment, chemotherapy, celiac plexus/ganglion neurolysis, radiotherapy, and endoscopic technique. This review discusses the medica...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Choe JW, Hyun JJ Tags: Korean J Gastroenterol Source Type: research

[Nutritional Support for Patients with Pancreatic Cancer].
Abstract Pancreatic cancer is the ninth common malignancy in South Korea. It has a dismal prognosis with a 5-year overall survival rate of less than 10%, and pancreatic cancer is associated with cancer cachexia, which is defined as the loss of muscle mass that is not reversible by conventional nutritional support. Cachexia is noted in over 85% of all pancreatic cancer patients and it is strongly related with the disease's mortality. Nearly 30% of pancreatic cancer deaths are due to cachexia rather than being due to the tumor burden. Therefore, it is crucial to discover the mechanisms behind the development of musc...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Jung MK Tags: Korean J Gastroenterol Source Type: research

[Emotional Support and Palliative Care for Distressed Patients Suffering from Pancreatic Cancer].
Abstract Pancreatic cancer is associated with a poor prognosis and high mortality. Thus, distress that includes depression and anxiety is a relatively common comorbidity for patients suffering from pancreatic cancer. However, these psychological symptoms are likely to be under-detected and undertreated. Regarding high levels of unmet needs of psychological support for patients with pancreatic cancer, early screening for distress and adequate interventions should be considered in palliative care settings. Suicide, a common but preventable cause of mortality for patients with pancreatic cancer, also deserves the fur...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Park HY Tags: Korean J Gastroenterol Source Type: research

Early Phase of Achalasia Manifested as an Esophageal Subepithelial Tumor.
Abstract The Chicago classification (CC) defines an esophagogastric junction outflow obstruction (EGJOO) as the presence of several instances of intact or weak peristalsis, elevated median integrated relaxation pressure above 15 mmHg, and a discrepancy from the criteria of achalasia. The revised CC addresses the potential etiology of EGJOO, including the early forms of achalasia, mechanical obstruction, esophageal wall stiffness, or manifestation of hiatal hernia. A 58-year-old woman visited the Presbyterian Medical Center with swallowing difficulty. The patient underwent a high resolution manometry (HRM) examinat...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Lee JH, Lee YJ, Lee JM, Ju MJ, Yang MA, Choi MW, Yun SH Tags: Korean J Gastroenterol Source Type: research

Ischemic Colitis Associated with Rhabdomyolysis and Heat Stroke after an Intense Exercise in Young Adult.
Abstract Ischemic colitis primarily affects the elderly with underlying disease, but it rarely occurs in young adults with risk factors, such as coagulopathy or vascular disorder. Moreover, it is extremely rare in the very young without risk factors. This paper presents a patient with ischemic colitis associated with heat stroke and rhabdomyolysis after intense exercise under high-temperature conditions. A 20-year-old man presented with mental deterioration after a vigorous soccer game for more than 30 minutes in sweltering weather. He also presented with hematochezia with abdominal pain. The laboratory tests reve...
Source: Korean J Gastroenter... - August 24, 2019 Category: Gastroenterology Authors: Cha S, Kwon BS, Hong N, Park JS, Byun SK, Choi SC, Kim YS Tags: Korean J Gastroenterol Source Type: research

[Early-onset Colorectal Cancer].
Abstract The incidence of colorectal cancer (CRC) is increasing among young adults in several countries including the United States. Early-onset colorectal cancer (EO-CRC) is heterogenous group and appears to have a distinct clinical, pathologic, and molecular presentation compared to CRC diagnosed in older patients. EO-CRC patients tend to be diagnosed at later stage and with symptomatic disease. Tumors arise predominantly in the distal colon and rectum and have poorer histological features. Microsatellite and chromosome stable molecular pathway is frequently observed in EO-CRC. Survival data of EO-CRC is conflic...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Jeong MA, Kang HW Tags: Korean J Gastroenterol Source Type: research

Risk Factors of Multiple Gastric Polyps according to the Histologic Classification: Prospective Observational Cohort Study.
Abstract Background/Aims: The aim of this study was to determine the risk factors of multiple gastric polyps according to the histological classification of gastric polyps. Methods: Subjects with multiple gastric polyps (at least three) during endoscopy were enrolled prospectively. They were assigned to a fundic gland polyp (FGP) group and hyperplastic polyp (HP) group based on a histological classification of gastric polyps. Helicobacter pylori (H. pylori) was confirmed by its histology. Serum gastrin was measured using the radioimmunoassay method. A questionnaire was taken regarding the intake of proton pum...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Jeong CY, Kim N, Lee HS, Yoon H, Shin CM, Park YS, Kim JW, Lee DH Tags: Korean J Gastroenterol Source Type: research

[Development of a Pancreatic Cancer Specific Binding Peptide Using Phage Display].
Conclusions: This study showed that the noble peptide, M5, binds specifically to the pancreatic cancer cell line, MIA PaCa-2. The M5 peptide has potential use in future optical diagnostic and therapeutic purposes. PMID: 31344770 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Lee DW, Park JM, Yang SM, Kwak MH, Roh YJ, Lee IS, Choi MG Tags: Korean J Gastroenterol Source Type: research

[Rapunzel Syndrome Removed with Enteroscopy in a Child].
Abstract A trichobezoar is a type of bezoar that is composed of hair. In most cases, it is confined to the stomach, but in rare cases, it may extend to the small intestine. This condition is referred to as Rapunzel syndrome. The therapeutic method for bezoar removal depends on its type, location, and size. Generally, the treatment for Rapunzel syndrome involves surgical laparotomy. Endoscopic removal has also been effective in some cases. On the other hand, complications, such as respiratory difficulty and esophageal impaction may be encountered during endoscopic removal. Until now, the successful endoscopic remov...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Chun SW, Lee K, Park YJ, Shin HD Tags: Korean J Gastroenterol Source Type: research

Colonic Diffuse Large B-cell Lymphoma Hidden in Actinomycosis.
Abstract Actinomycosis can mask malignant diseases. This paper reports a case of colonic diffuse large B-cell lymphoma (DLBCL), which was misdiagnosed as abdominal actinomycosis. A 76-year-old woman presented with right flank pain and weight loss. Abdominal CT and colonoscopy revealed a huge ascending colon mass. Despite the initial impression of a malignancy, a colonoscopic biopsy revealed no malignant cells, but sulfur granules and a filamentous organism suggesting actinomycosis. Intravenous penicillin G was administered under the impression of abdominal actinomycosis but her condition deteriorated rapidly. Foll...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Lee SH, Nam SJ, Lee SJ, Park SC, Kang CD, Choi DH, Park JM, Lee SK Tags: Korean J Gastroenterol Source Type: research

[Impaction of Coin Battery in the Appendix].
Abstract Coin batteries are often used in daily life devices and can be easily available. Children can swallow coin batteries, resulting in the need to go to hospital, but this is rare in adults. Adults generally eliminate the swallowed coin battery from the digestive system, unless they have congenital structural abnormalities of the digestive system or complications, such as postoperative stenosis. In this case, a 31-year-old man swallowed three coin batteries, approximately 0.4 cm in diameter emergent endoscopy was unable to find any batteries embedded in the ingested food. An attempt was made to rinse out the ...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Rim CB, Song KH Tags: Korean J Gastroenterol Source Type: research

Synchronous Primary Leiomyosarcoma in the Thoracic Vertebra and the Liver.
Abstract This is a case report of simultaneous primary leiomyosarcomas in the spine and liver. A 64-year-old woman presented to the Seoul Paik Hospital with epigastric discomfort and constipation that she had experienced for two months. A physical examination revealed severe tenderness around the thoraco-lumbar junction. Esophagogastroduodenoscopy showed an ulceroinfiltrative lesion on the gastric angle. An abdominopelvic CT scan revealed two low attenuated lesions in the S4 and S8 regions of the liver, as well as a soft tissue mass at the T10 vertebra. Percutaneous ultrasonography-guided needle biopsy of the hepa...
Source: Korean J Gastroenter... - July 25, 2019 Category: Gastroenterology Authors: Kim YK, Kim JA, Ryu SH, Choi JH, Tsung PC, Park JH, Moon JS, Shim JC, Lee HK, Loutzenhiser JM Tags: Korean J Gastroenterol Source Type: research

[Medical Dispute Related to Gastrointestinal Endoscopy Complications: Prevention and Management].
Abstract Because gastrointestinal (GI) endoscopy examinations are being performed increasingly frequently, the rate of detection of cancer and of precancerous lesions has increased. Moreover, development of more advanced endoscopic technologies has expanded the indications for, and thus frequency of, therapeutic endoscopic procedures. However, the incidence of complications associated with diagnostic or therapeutic GI endoscopy has also increased. The complications associated with GI endoscopy can be ameliorated by endoscopic or conservative treatment, but caution is needed as some of the more serious complication...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Jung Y Tags: Korean J Gastroenterol Source Type: research

[Emerging Issues in Esophageal Motility Diseases].
Abstract With the advances in technology and medical knowledge, new diseases are being identified and investigated. Esophageal motility disorders have been re-defined using high-resolution manometry and their pathogenesis are being better understood. The use of opioid analgesics is increasing worldwide, particularly in the United States, but their chronic use can cause opioid-induced esophageal dysfunction, which mimics spastic motor disorders, including achalasia type 3 or 2 and esophagogastric junction outflow obstruction. Eosinophilic esophagitis is identified by eosinophilic infiltration confirmed on a patholo...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Kim GH, Jung KW Tags: Korean J Gastroenterol Source Type: research

[Nodular Gastritis as a Precursor Lesion of Atrophic and Metaplastic Gastritis].
This study aimed to identify the characteristics of nodular gastritis (NG) showing CAG or MG after nodule regression. Methods: H. pylori-infected patients with NG were included after upper gastrointestinal endoscopy. Patients were excluded if their latest endoscopy had been performed ≤36 months after the initial diagnosis of NG. Small-granular-type NG was defined as the condition with 1-2 mm regular subepithelial nodules. Large-nodular-type NG was defined as those with 3-4 mm, irregular subepithelial nodules. The endoscopic findings after nodule regression were recorded. Results: Among the 97 H. pylori-infecte...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Kim YJ, Lee SY, Yang H, Kim JH, Sung IK, Park HS Tags: Korean J Gastroenterol Source Type: research

[Development of Koreans Gut Quotient Measurement Scales].
Conclusions: The GQ, which is a simplified intestinal health index developed based on an easy questionnaire for the public to understand, can be used as a tool for the public to evaluate their own intestinal health and determine when to visit clinics. PMID: 31234624 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Choi YJ, Cho JH, Lee DH, Song DJ, Kwon YJ, Baek SM, Kim YJ, Jang MH, Lee DH, Park HY, Kim MC, Yang JA Tags: Korean J Gastroenterol Source Type: research

Primary Gastric Choriocarcinoma Coexisting with Adenocarcinoma.
Abstract Choriocarcinoma is an aggressively growing and widely metastasizing tumor that originates from trophoblastic cells. A primary gastric choriocarcinoma (PGC), however, is very rare. A 76-year-old female patient visited the emergency department of Wonkwang University Hospital with abdominal discomfort and melena. Esophagogastroduodenoscopy revealed a huge ulceroinfiltrative mass lesion with blood clots on the boundary between the greater curvature side and the posterior wall side of the stomach lower body. CT showed a 3-cm exophytic mass lesion with heterogeneous enhancement, an ulcer lesion at the posterior...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Lee JH, Lee JK, Kang DB Tags: Korean J Gastroenterol Source Type: research

[Intussusception Caused by Colon Cancer in Pregnancy].
Abstract Intussusception is a common in pediatric age group. But it is rare in adults. And intussusception caused by tumor account for 1% of bowel obstructions in adult. Intussusception is an extremely rare cause of abdominal pain in pregnancy. In particular, cases of Intussusception due to colorectal cancer during pregnancy have never been reported in Korea. Our patient is a 34 years old woman who presented at 14 weeks of her second pregnancy. She presented with right lower abdominal discomfort and intermittent palpable mass which was usually spontaneously resolved. In the MRI study, pathologic asymmetric wall th...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Kim K, Ko M, Sim HC, Kim CL, Jung YJ, Kim TO Tags: Korean J Gastroenterol Source Type: research

[Drug Induced Liver Injury by Prophylactic Administration of Albendazole].
Abstract Albendazole is used as a typical antiparasitic agent worldwide. The side effects of albendazole may include nausea, vomiting, abdominal pain, dizziness, headache, alopecia, and increased liver enzymes. Mild elevation of the liver enzyme has been reported in more than 10% of cases, but drug induced liver injury was reported to be very rare. A 30-year-old woman visited the Dong-A University Hospital with anorexia, nausea, jaundice, and elevated liver enzyme. For diagnosis, other acute hepatitis etiologies were excluded, but the prophylactic administration of albendazole was verified. This paper introduces a...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Moon SY, Baek YH, Lee SW Tags: Korean J Gastroenterol Source Type: research

Feasibility of Adopting the "Step-up Approach" in Managing Necrotizing Pancreatitis-induced Pancreatic-colonic Fistula.
Feasibility of Adopting the "Step-up Approach" in Managing Necrotizing Pancreatitis-induced Pancreatic-colonic Fistula. Korean J Gastroenterol. 2019 Jun 25;73(6):365-369 Authors: Yim SK, Kim SH, Seo SY, Yang HC, Lee SO Abstract Managing acute pancreatitis is clinically challenging because of the generally poor patient condition, the variety of treatment options depending on the severity and complications, and the uncertainty of outcomes. Recently, the step-up approach, which involves less invasive initial treatment and more invasive subsequent treatment, where necessary, has been proposed as...
Source: Korean J Gastroenter... - June 25, 2019 Category: Gastroenterology Authors: Yim SK, Kim SH, Seo SY, Yang HC, Lee SO Tags: Korean J Gastroenterol Source Type: research

[Rectal Ulcer Developed in Systemic Lupus Erythematosus without Ischemic Colitis].
Abstract Rectal involvement by systemic lupus erythematosus (SLE) is quite rare. Approximately 14 cases have been reported worldwide, but only one with ischemic colitis has been reported in Korea. A 17-year-old female patient was hospitalized with abdominal pain and hematochezia. Sigmoidoscopy revealed only a simple rectal ulcer without ischemic colitis. cytomegalovirus and bacterial infections were excluded. A sigmoidoscopic rectal biopsy indicated a rectal invasion by SLE, but the patient showed an acute worsening conditions that did not respond to treatment. This paper reports a case of rectal ulcer that develo...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Sohn KC, Heo WG, Chu MS, Kim EJ, Chung JH, Choi SC, Yun KJ, Seo GS Tags: Korean J Gastroenterol Source Type: research

Cystic Degeneration of Hepatocellular Carcinoma Mimicking Mucinous Cystic Neoplasm.
Abstract Spontaneous regression of tumors is an extremely rare event in hepatocellular carcinoma (HCC) with only a few reports available. With the accumulation of clinical information and tumor immunogenetics, several mechanisms for the cystic changes of HCC have been suggested, including arterial thrombosis, inflammation, and rapid tumor growth. This paper reports an uncommon case of the partial regression of HCC, which was initially misdiagnosed as a mucinous cystic neoplasm of the liver due to the unusual radiologic findings. A 78-year-old female with the hepatitis B virus and liver cirrhosis presented with an ...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Lee J, Lee N, Yoon HK, Lee YJ, Park SJ Tags: Korean J Gastroenterol Source Type: research

[Introduction of Hospitalists and Their Role in Gastroenterology].
Abstract A hospitalist system in Korea began in August 2016. Patient safety issues, resident law, and reduction of resident numbers in Korea are leading to an increase in the demand for hospitalist in Korea. The roles and responsibilities of GI hospitalists have not been established. Therefore, cooperation among the Korean society of gastroenterology, each hospital, and government is necessary. In particular, it is important to prepare an education program for gastroenterology hospitalists. PMID: 31132830 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Kim JH, Song TJ Tags: Korean J Gastroenterol Source Type: research

[Hepatobiliary Manifestation of Inflammatory Bowel Disease].
Abstract The hepatobiliary system is one of the most common sites of extraintestinal manifestation in patients with inflammatory bowel disease (IBD). The progression of IBD can lead to a primary hepatobiliary manifestation and can occur secondary to multiple drugs or accompanying viral infections. Primary sclerosing cholangitis is the representative hepatobiliary manifestation of IBD, particularly in ulcerative colitis. Although most agents used in the treatment of IBD are potentially hepatotoxic, the risk of serious hepatitis or liver failure is low. The prevalence of HBV and HCV in IBD is similar to the general ...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Seo KI, Kang SB Tags: Korean J Gastroenterol Source Type: research

[Renal and Urinary Manifestations of Inflammatory Bowel Disease].
Abstract The incidence of inflammatory bowel disease (IBD) is increasing rapidly and extra-intestinal manifestations in IBD are also increasing. The prevalence of renal and urinary involvement in IBD ranges from 4-23%. Nephrolithiasis is the most common urinary complication in IBD patients. Parenchymal renal disease is rare but has been well documented and presents most commonly as glomerulonephritis or tubulointerstitial nephritis. The overall morbidity of IBD-related renal manifestations is significant. Therefore, a high index of clinical suspicion and optimal monitoring of the renal function are needed for the ...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Kim YN, Jung Y Tags: Korean J Gastroenterol Source Type: research

Ophthalmologic Manifestation of Inflammatory Bowel Disease: A Review.
Abstract In patients with inflammatory bowel disease (IBD), ocular extraintestinal manifestations (EIM) are less common than EIM of other systems, but they are clinically important because they can lead to complications that can cause catastrophic damage to the visual acuity and ocular structure. Anterior uveitis and episcleritis are the most common ocular EIM. Involvement of the orbit, posterior segment, and optic nerve can also occur. A variety of treatments are available ranging from topical steroids to systemic immunosuppressive therapies. The treatment of IBD is also essential if the activity of inflammatory ...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Lee DH, Han JY, Park JJ, Cheon JH, Kim M Tags: Korean J Gastroenterol Source Type: research

[Musculoskeletal Manifestation in Inflammatory Bowel Disease].
Abstract Almost 50% of patients with inflammatory bowel disease (IBD) exhibit at least one extra-intestinal manifestation in their lifetime. Extra-intestinal manifestations of IBD are often associated with the intestinal disease activity, reducing the quality of life of the patient but rarely leading to fatal complications. Musculoskeletal involvement is the most frequent extra-intestinal manifestation of patients with IBD but this rarely occurs before IBD is diagnosed. They are manifested in various forms, such as arthropathy, fibromyalgia, and osteoporosis. Therefore, a multidisciplinary team approach including ...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Kim YS, Lee J Tags: Korean J Gastroenterol Source Type: research

[Dermatologic Manifestations in Inflammatory Bowel Disease].
Abstract Inflammatory bowel disease (IBD) is a chronic inflammatory disease of the gastrointestinal tract with an unknown etiology and pathogenesis. The incidence and prevalence of IBD are increasing rapidly in Korea. Approximately one-third of patients with IBD appear to develop extra-intestinal manifestations with the skin being one of the most commonly affected organs. They may precede, occur simultaneously, or follow the diagnosis of IBD. In addition, they may parallel with the luminal symptoms or independent from the disease activity of IBD. This review outlines the skin manifestations associated with IBD and...
Source: Korean J Gastroenter... - May 25, 2019 Category: Gastroenterology Authors: Suh HY, Lee WJ, Na SY Tags: Korean J Gastroenterol Source Type: research

Prevalence of Functional Gastrointestinal Disorders in School Children and Adolescents.
Conclusions: The overall prevalence of FGID in the sample was 30%, with functional constipation being the most common. These results are similar to those of other prevalence studies reported elsewhere. PMID: 31030457 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Peralta-Palmezano JJ, Guerrero-Lozano R Tags: Korean J Gastroenterol Source Type: research

Comparison of the Diagnostic Performances of Same-session Endoscopic Ultrasound- and Endoscopic Retrograde Cholangiopancreatography-guided Tissue Sampling for Suspected Biliary Strictures at Different Primary Tumor Sites.
Conclusions: EUS-TS was found to be superior to ERCP-TS for evaluating suspected biliary strictures, especially those caused by pancreatic lesions. PMID: 31030458 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Yeo SJ, Cho CM, Jung MK, Seo AN, Bae HI Tags: Korean J Gastroenterol Source Type: research

Successful Treatment Using Endoluminal Vacuum Therapy after Failure of Primary Closure in Boerhaave Syndrome.
Abstract Boerhaave syndrome is a transmural perforation of the esophagus and typically occurs after forceful emesis. Boerhaave syndrome is a destructive disease with a high mortality rate, though surgical intervention within 24 hours has a beneficial effect. On the other hand, late surgical intervention is associated with poorer prognoses. Several therapeutic strategies, ranging from medical to surgical management, are available for Boerhaave syndrome. Recently, endoscopic endoluminal vacuum therapy (EVT) was introduced as a treatment option. Here, we report the case of a 56-year-old male patient with Boerhaave sy...
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Kim YE, Do YW, Cho JY, Kim ES, Lee DH Tags: Korean J Gastroenterol Source Type: research

Recurrent Eosinophilic Pneumonia Associated with Mesalazine Suppository in a Patient with Ulcerative Colitis.
Abstract Mesalazine suppositories are widely used to treat ulcerative colitis and have a guaranteed safety profile, but although rare, they can cause pulmonary toxicity. A 35-year-old woman with ulcerative colitis was diagnosed to have acute eosinophilic pneumonia after 29 days of oral mesalazine use and improved after mesalazine and corticosteroid were withdrawn. Reintroduction of mesalazine suppositories resulted in acute eosinophilic pneumonia recurrence after 28 days. Mesalazine re-administration (even via a different route) in patients with a history of mesalazine-induced eosinophilic pneumonia should be unde...
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Park M, Lee J, Kang SB, Park Y Tags: Korean J Gastroenterol Source Type: research

Concomitant Liver and Brain Abscesses Caused by Parvimonas Micra.
Abstract Anaerobic infections have been reported to be responsible for 3-10% of pyogenic liver abscesses in Korea, and reported anaerobes include Fusobacterium, Bacillus fragilis, and Bacteroides melaninogenicus. Parvimonas micra is an anaerobic, Gram-positive, non-spore-forming bacterial species and a constituent of normal flora on skin, vagina, gastrointestinal tract, and oral cavity that can cause opportunistic infections. However, it has only rarely been reported to be a cause of liver abscess; only one such case has been reported in Korea. We experienced a case of concomitant liver and brain abscesses caused ...
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Kim EY, Baek YH, Jung DS, Woo KS Tags: Korean J Gastroenterol Source Type: research

Mucinous Non-neoplastic Cyst of the Pancreas.
Abstract Cystic neoplasms of the pancreas consist of a wide range of pathological entities and are being detected more frequently due to advances in cross-sectional imaging modalities and increasing numbers of periodic health checkups. The majority of pancreatic cystic neoplasms are intraductal papillary mucinous neoplasms, serous neoplasms, and mucinous cystic neoplasms, but recently, rare cases of mucinous non-neoplastic cyst of the pancreas (MNCP) have been reported, and despite the availabilities of modern imaging systems, such as MRI and CT, the differentiation of non-neoplastic and neoplastic cysts remains c...
Source: Korean J Gastroenter... - April 25, 2019 Category: Gastroenterology Authors: Kim JH, Park DE, Choi KH Tags: Korean J Gastroenterol Source Type: research

Curative Loco-regional Therapies for Early Hepatocellular Carcinoma: Is Combination Effective?
PMID: 31013554 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Lee SH Tags: Korean J Gastroenterol Source Type: research

Recent Updates in the Management of Advanced Pancreatic Neuroendocrine Tumors.
In conclusion, pNETs are diagnosed increasingly throughout the world, usually with metastatic disease and requiring systemic therapy. Each patient should be evaluated thoroughly and discussed individually by a multidisciplinary and dedicated NET-expert team, which might consider all treatment options, including ongoing clinical trials before selecting the appropriate treatment sequence. PMID: 31013555 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Cho CM Tags: Korean J Gastroenterol Source Type: research

2018 Korean Association for the Study of the Liver (KASL) Clinical Practice Guidelines of Chronic Hepatitis B: What's Different?
Abstract The clinical practice guideline for the management of chronic hepatitis B (CHB) was originally enacted in 2004 by the Korean Association for the Study of the Liver in order to provide medical practitioners with specific medical information regarding CHB to help them facilitate their understanding of the disease and treatment of the infected patients. Other than an update on the treatment of antiviral resistance in 2014, which is a partial revision, the guidelines for the treatment of chronic hepatitis B have been revised entirely three times in 2007, 2011, and 2015. Although several major international li...
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Kim JH Tags: Korean J Gastroenterol Source Type: research

Prediagnostic Smoking and Alcohol Drinking and Gastric Cancer Survival: A Korean Prospective Cohort Study.
We examined associations between prediagnostic smoking and alcohol drinking behavior and GC death by long-term follow-up. Methods: The participants were 508 GC patients enrolled at Chungnam University Hospital and Hanyang University Guri Hospital from 2001 to 2006. Information on clinicopathologic and behavioral risk factors was collected, and patient survival was prospectively followed until 2016 by medical chart review and telephone survey. Results: During above 10 years follow-up period, overall death was 46.2% (n=226) and GC deaths was 38.2% (n=187) among the 489 GC patients included in the analysis. No signi...
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Kim SA, Choi BY, Song KS, Park CH, Eun CS, Han DS, Kim YS, Kim HJ Tags: Korean J Gastroenterol Source Type: research

Complications Following Colonoscopy in a Nationwide Standard Cohort: A Retrospective Case-control Study.
In this study, a population-based study was performed to evaluate the incidence of post-colonoscopy perforations compared to a control group. Methods: Between January 2011 and December 2011, data for all cases (age over 45) who underwent a colonoscopy were collected from National Health Insurance Service using a random sampling method. The clinical characteristics and perforation incidence (within 30 days after the colonoscopy) of cases were identified, and cases were then compared with controls who had not undergone a colonoscopy. Results: Among 1,380,000 subjects, 31,177 cases and 62,354 controls were identifie...
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Kim JW, Kim SY, Choi JH, Kim HS, Lee JK, Kim YT, Park G, Kang DR Tags: Korean J Gastroenterol Source Type: research

The Clinical Significance of Microsatellite Instability in Patients with Right-sided Colorectal Cancer.
Conclusions: The study shows MSI is a useful predictor of DFS in patients with right-sided CRC, especially in female patients. PMID: 31013559 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Han SA, Kim JH, Choi JH, Lee DH, Jung K, Kim SE, Moon W, Park MI, Park SJ Tags: Korean J Gastroenterol Source Type: research

Efficacy and Safety of Combined Radiofrequency Ablation with Transarterial Chemoembolization in Patients with Barcelona Clinic Liver Cancer Stage A Hepatocellular Carcinoma Ineligible for Curative Treatment.
Conclusions: Combination of RFA was an efficient and safe treatment for BCLC stage A HCC patients that failed to achieve complete response to initial TACE. We suggest TACE plus RFA be considered as a curative option for early HCC patients ineligible for curative resection of RFA. PMID: 31013560 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Kim AR, Park E, Kwon SY, Park SJ, Kim YJ, Yoo BC, Choe WH, Kim JH, Hwang JH, Park SW, Kim YJ, Park HS, Yu MH, Jeon HJ Tags: Korean J Gastroenterol Source Type: research

Benign Gastric Ulcer with Epstein-Barr Virus Infection Mimicking Malignant Gastric Ulcer.
We report a case of benign gastric ulcer with EBV infection confirmed by endoscopic and histological findings. PMID: 31013561 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Gwak JW, Yoo J, Suh SO, Kim J, Oh IS, Bae JY Tags: Korean J Gastroenterol Source Type: research

Pancreatic Metastasis from Adenocarcinoma of the Uterine Cervix.
We report a case of metastatic adenocarcinoma of the pancreas from uterine cervical cancer. A 70-year-old woman was referred because of a pancreatic mass detected by CT. She had been diagnosed with uterine cervical adenocarcinoma 20 months previously. After concurrent chemoradiotherapy, CT showed no evidence of the cervical mass, and follow-up showed no evidence of recurrence. Endoscopic ultrasound-guided fine needle aspiration biopsy of the pancreatic mass resulted in a diagnosis of metastatic adenocarcinoma from uterine cervix. PMID: 31013562 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Kim DJ, Park JM, Kim JH, Nam K, Kang CD, Lee SJ, Lee K, Jeon YH Tags: Korean J Gastroenterol Source Type: research

New Concept of Hepatocellular Carcinoma Treatment with the Tumor Suppressor 'WDR76' through 'RAS' Degradation.
PMID: 31013564 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2019 Category: Gastroenterology Authors: Park JY Tags: Korean J Gastroenterol Source Type: research

[Gastroesophageal Reflux Disease].
Abstract Gastroesophageal reflux disease (GERD) is a condition that develops when reflux of stomach contents causes troublesome symptoms and/or complications. The prevalence of GERD is increasing worldwide and in Asia-Pacific. The latest Korean guidelines for GERD were published in 2012, and several international guidelines and consensus statements for the management of GERD have also been recently published. Here, we review these guidelines and consensus statements in order to provide a better understanding of the diagnosis and treatment of GERD. PMID: 30845382 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - February 25, 2019 Category: Gastroenterology Authors: Park CH, Lee SK Tags: Korean J Gastroenterol Source Type: research

[Functional Dyspepsia].
Abstract Dyspepsia is a common problem, and when dyspeptic symptoms develop within a short period of time, organic diseases such as gastroesophageal reflux disease, peptic ulcer diseases, pancreatoduodenal diseases, and gastrointestinal cancers should be suspected. Furthermore, functional dyspepsia (FD) should be considered if chronic or recurrent symptoms persist after eliminating underlying disease. FD is classified as epigastric pain syndrome (EPS) or postprandial distress syndrome (PDS), but these two conditions may overlap. Patients with the EPS subtype can be treated with proton pump inhibitors (PPIs), where...
Source: Korean J Gastroenter... - February 25, 2019 Category: Gastroenterology Authors: Oh JH, Kwon JG Tags: Korean J Gastroenterol Source Type: research

[Irritable Bowel Syndrome].
Abstract Irritable bowel syndrome (IBS) is a common functional gastrointestinal disorder. Its diagnosis is based on symptoms, and the Rome IV criteria are recognized as the gold diagnostic standard. The Korean Society of Neurogastroenterology and Motility (KSNM) recently updated their clinical practice guidelines for the treatment of IBS, which were last issued in 2011. In this updated edition, the KSNM defines IBS as a chronic, recurrent symptom complex that includes abdominal pain or discomfort, changes in bowel habits, and bloating for at least 6 months, which is somewhat broader than the previous definition. F...
Source: Korean J Gastroenter... - February 25, 2019 Category: Gastroenterology Authors: Kim JH, Jee SR Tags: Korean J Gastroenterol Source Type: research

[Chronic Functional Constipation].
Abstract Constipation is a common functional problem of the digestive system and may occur secondary to diet, drugs, endocrine diseases, metabolic diseases, neurological diseases, psychiatric disorders, or gastrointestinal obstruction. When there is no secondary cause, constipation is diagnosed as functional constipation. The first steps that should be taken to relieve symptoms are diet and lifestyle modifications, and if unsuccessful, laxative therapy should be initiated. If a patient does not respond to laxative therapy, diagnostic anorectal physiological tests are performed, though they are not routinely recomm...
Source: Korean J Gastroenter... - February 25, 2019 Category: Gastroenterology Authors: Shin JE, Park KS, Nam K Tags: Korean J Gastroenterol Source Type: research

[Eradication Rates of 10-day Sequential Therapy for Helicobacter pylori: Results of an 8-year Prospective Study Conducted at a Tertiary Korean Hospital].
Conclusions: Despite high antibiotic resistance rates in Korea, the eradication rate of SQT did not decrease over the 8-year study period. PMID: 30845386 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - February 25, 2019 Category: Gastroenterology Authors: Yoon K, Kim N Tags: Korean J Gastroenterol Source Type: research