[Post-colonoscopy Colorectal Cancer: Causes and Prevention of Interval Colorectal Cancer].
Abstract Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in the worldwide. Colonoscopy is the gold standard for screening and surveillance of CRC. Removing adenomas by colonoscopy has lowered the incidence and mortality of CRC. However, colonoscopy is imperfect for detection of colorectal neoplasia. After a colonoscopy that is negative for malignancy, CRC can be diagnosed. These are termed as post-colonoscopy CRC (PCCRC). The proportion of PCCRC, among all CRC was reported to be 1.8% to 9.0%. It occurred 2.4 times more in the right colon than in the ...
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Lee JY, Lee JH Tags: Korean J Gastroenterol Source Type: research

[Guidelines for Non-variceal Upper Gastrointestinal Bleeding].
Abstract Non-variceal upper gastrointestinal bleeding (NVUGIB) refers to bleeding that develops in the gastrointestinal tract proximal to the ligament of Treitz. NVUGIB is an important cause for visiting the hospital and is associated with significant morbidity and mortality. Although European and Asian-Pacific guidelines have been published, there has been no previous guidelines regarding management of NVUGIB in Korea. Korea is a country with a high prevalence of Helicobacter pylori infection and patients have easy accessibility to receive endoscopy. Therefore, we believe that guidelines regarding management of N...
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Kim JS, Kim BW, Kim DH, Park CH, Lee H, Joo MK, Jung DH, Chung JW, Choi HS, Baik GH, Lee JH, Song KY, Hur S Tags: Korean J Gastroenterol Source Type: research

[Therapeutic Response to 20 mg of Esomeprazole Twice Daily in Patients with Gastroesophageal Reflux Disease-related Non-cardiac Chest Pain: An Open-Label Randomized Pilot Study].
Conclusions: Esomeprazole BD was as effective as esomeprazole OD in improving GERD-related NCCP. Although statistically insignificant, the percentage of patients with>50% reduction in the chest pain score was higher in the esomeprazole BD group than in the esomeprazole OD group. Large-scale studies will be needed to assess these findings further. PMID: 32581204 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Choi JK, Shim HI, Shin CM, Yoon H, Park YS, Kim N, Lee DH Tags: Korean J Gastroenterol Source Type: research

Usefulness and Complications of Needle Knife Fistulotomy as a Rescue Procedure in Patients with Pancreaticobiliary Disease.
Conclusions: NKF is an effective and safe method that can be considered for rescue management after the initial failure of standard cannulation or DGT. NKF following standard cannulation can be preferred over NKF following DGT because of the higher success rate and the lower rate of pancreatitis, but the difference was not significant. PD stenting in patients at high risk of PEP can be considered to decrease pancreatitis. PMID: 32581205 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Lee YJ, Kang DH, Kim HW, Park SB, Kim SJ, Nam HS, Ryu DG Tags: Korean J Gastroenterol Source Type: research

[Post-meningitis Dumping Syndrome: A Case Report and Literature Review].
Abstract Dumping syndrome has long been associated with gastric surgery. The authors experienced an adult patient presenting with dumping syndrome after meningitis without any previous surgical procedures on the stomach and small bowel. Dysfunction of the autonomic nervous system after infective meningitis may originate from postinfectious sequelae or an immunologic mechanism. A comprehensive study and proper management of autonomic symptoms of patients with a central nervous system infection are needed. PMID: 32581206 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Park JH, Park YE, Kang MR Tags: Korean J Gastroenterol Source Type: research

[Gallbladder Perforation after Transarterial Chemoembolization in a Patient with a Huge Hepatocellular Carcinoma].
Abstract Transarterial chemoembolization (TACE) is a common treatment for unresectable hepatocellular carcinoma (HCC). The most common complications after TACE are non-specific symptoms called post-embolization syndrome, such as abdominal pain or fever. Rare complications, such as liver failure, liver abscess, sepsis, pulmonary embolism, cholecystitis, can also occur. On the other hand, gallbladder perforation is quite rare. This paper reports a case of gallbladder perforation following TACE. A 76-year-old male with a single 9-cm-sized HCC underwent TACE. Five days after TACE, he developed persistent right upper q...
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Son MY, Han BH, Lee SU, Yun BC, Seo KI, Huh JD Tags: Korean J Gastroenterol Source Type: research

Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis.
Abstract Autoimmune pancreatitis (AIP) is a rare and unique type of chronic pancreatitis. The prognosis of AIP, particularly when associated with pancreatic cancer or a related malignancy, is not known. Only a few cases, where metachronous pancreas-related cancer developed during follow-up, have been reported. Most of these patients either underwent surgery or steroid therapy. This paper reports a case of a 66-year-old woman with untreated type I AIP who developed peritoneal carcinomatosis more than 2 years later. Initially, the patient had a markedly elevated serum IgG4 level and a diffuse, infiltrative mass-like...
Source: Korean J Gastroenter... - June 25, 2020 Category: Gastroenterology Authors: Lee KW, Chang JH, Kim J, Kim TH, Kim CW, Kim JK, Han SW Tags: Korean J Gastroenterol Source Type: research

[Gut Microbiota and Pancreatobiliary System].
Abstract The gut microbiota is part of the human body that is involved in body metabolism and the occurrence of various diseases. Detecting and analyzing their genetic information (microbiome) is as important as analyzing human genes. The core microbiome, the key functional genes shared by all humans, helps better understand the physiology of the human body. Information on the gut microbiome of a diseased person can help diagnose and treat disease. The pancreatobiliary system releases functional antimicrobial substances, such as bile acids and antimicrobial peptides, which affect the gut microbiota directly. In re...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Ryu KH Tags: Korean J Gastroenterol Source Type: research

[Obesity and Pancreatobiliary Disease].
This study reviewed the literature on obesity and pancreatobiliary disease in terms of epidemiology and mechanism. PMID: 32448855 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Lee H, Koh DH Tags: Korean J Gastroenterol Source Type: research

[Novel Insights of Primary Sclerosing Cholangitis and Primary Biliary Cholangitis].
Abstract Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated chronic liver diseases. PSC is a rare disorder characterized by multi-focal bile duct strictures and progressive liver diseases that ultimately results in the need for liver transplantation in most patients. Imaging studies, such as MRCP, have an essential role in the diagnosis of most cases of PSC. PSC is usually accompanied by inflammatory bowel disease, and there is a high risk of cholangiocarcinoma and colorectal cancer in PSC. No medical therapies have been proven to delay the progression of PSC. Endoscopic...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Ahn DW Tags: Korean J Gastroenterol Source Type: research

[Recent Updates of Immunoglobulin G4-related Pancreatobiliary Disease].
Abstract Type 1 autoimmune pancreatitis and IgG4-related sclerosing cholangitis (IgG4-SC) are the pancreatobiliary manifestations of IgG4-related disease. IgG4-related disease is a newly named fibroinflammatory condition that is characterized by tumefactive lesions that contain dense lymphoplasmacytic infiltrates rich in IgG4-positive cells and often by elevated serum IgG4 concentrations. IgG4-related pancreatobiliary disease is often disguised as pancreatobiliary malignancies owing to its tumefactive nature and clinical presentations, such as obstructive jaundice. The differentiation of IgG4-SC from primary scler...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Lee GC, Moon SH Tags: Korean J Gastroenterol Source Type: research

[Clinical Practice Guideline for Endoscopic Resection of Early Gastrointestinal Cancer].
Abstract Although surgery was the standard treatment for early gastrointestinal cancers, endoscopic resection is now a standard treatment for early gastrointestinal cancers without regional lymph node metastasis. High-definition white light endoscopy, chromoendoscopy, and image-enhanced endoscopy such as narrow band imaging are performed to assess the edge and depth of early gastrointestinal cancers for delineation of resection boundaries and prediction of the possibility of lymph node metastasis before the decision of endoscopic resection. Endoscopic mucosal resection and/or endoscopic submucosal dissection can b...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Park CH, Yang DH, Kim JW, Kim JH, Kim JH, Min YW, Lee SH, Bae JH, Chung H, Choi KD, Park JC, Lee H, Kwak MS, Kim B, Lee HJ, Lee HS, Choi M, Park DA, Lee JY, Byeon JS, Park CG, Cho JY, Lee ST, Chun HJ Tags: Korean J Gastroenterol Source Type: research

Gastric Ulcer Perforation to the Liver Diagnosed by Endoscopic Biopsy.
Abstract Peptic ulcer disease is common and can be diagnosed easily if the patient has an ulcer history or characteristic abdominal symptoms. On the other hand, it may take a long time for the patient to visit the hospital due to severe complications if the patient is old or insensitive to symptoms caused by peptic ulcers. In the present case, a 72-year-old female visited the hospital due to general weakness and inadequate oral intake, which started two weeks ago. Endoscopy and abdominal CT revealed huge gastric ulcer findings. Through a tissue examination by endoscopy, hepatic cells were identified, and the patie...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Lee SU, Jee SR, Lee HS, Lee SH Tags: Korean J Gastroenterol Source Type: research

Endoscopic Treatment of a Twisted Small Bowel Obstruction after Laparoscopic Proximal Gastrectomy with Double Tract Reconstruction.
Abstract This paper reports a case of a twisted small bowel obstruction in a 74-year-old man that occurred after a double tract reconstruction (DTR) in a laparoscopic proximal gastrectomy (PG) for early gastric cancer. The patient had inadequate oral intake and reflux symptoms for 10 days after discharge. Imaging analysis revealed a narrowed small bowel with twists between the esophagojejunostomy and gastrojejunostomy sites. A fully covered stent was placed in the narrowed small bowel for 2 weeks. The patient was then discharged after stent removal without any dietary problems. The authors' experience shows that t...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Park KB, Jeon SW Tags: Korean J Gastroenterol Source Type: research

Pyogenic Liver Abscess or Liver Cyst Infection after Colonoscopic Polypectomy.
Abstract A pyogenic liver abscess (PLA) mostly occurs in association with biliary tract disease, but some PLAs have no apparent underlying cause, i.e., they are cryptogenic. The authors experienced three cases of PLA or liver cyst infection after colon polypectomy without other distinct etiologies. These cases suggest that colonoscopic polypectomy can cause a mucosal defect that provides a route for bacteria to invade the portal system or spread intraperitoneally to the liver. Colonoscopic polypectomy should be considered as a procedure that might cause PLA. Moreover, clinicians should be aware of this possibility...
Source: Korean J Gastroenter... - May 25, 2020 Category: Gastroenterology Authors: Kim TH, Heo NY, Park SH, Moon YS, Kim TO, Park J, Choi JH, Park YE, Lee J Tags: Korean J Gastroenterol Source Type: research

Liver Dysfunction in Sepsis.
Abstract Sepsis is defined as a life-threatening organ dysfunction caused by a dysregulated host response to infection. During sepsis, the liver has essential roles, such as immune defense and metabolic adaptation to inflammation. In addition, it is a target for sepsis-related injury, including hypoxic hepatitis, cholestasis, drug-induced liver injury, and secondary sclerosing cholangitis in critically ill patients. In particular, the mortality rate due to sepsis is four times higher in patients with cirrhosis, warranting a high index of suspicion for infection, appropriate diagnosis, and prompt antimicrobial trea...
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Kim TS, Choi DH Tags: Korean J Gastroenterol Source Type: research

Clinical Characteristics of Campylobacter Enterocolitis in Korean Adults: A Retrospective Study at a Single Center.
Conclusions: Campylobacter enterocolitis was common during summer. Commonly healthy young adults were hospitalized due to severe symptoms of Campylobacter enterocolitis. Whole colon and small bowel were frequently involved. Most patients were treated with antibiotics, and the efficacy of 3rd cephalosporin treatment was not inferior to that of ciprofloxacin treatment. PMID: 32326685 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Yoo M, Chung SH, Park YS, Oh IH, Chae WY, Kim SH, Lee KY, Song CW, Son BK, Kim SH, Jo YK, Jung KH, Lee HY, Chae JD Tags: Korean J Gastroenterol Source Type: research

Effect of Cancer Awareness on Treatment Decision for Pancreatic Cancer Patients.
Abstract Background/Aims: With recent changes in the treatment of pancreatic cancer, patients' active decision-making has become more important. Nevertheless, it is difficult to give patients proper insights into the disease. The purpose of this study was to determine associated factors between pancreatic cancer awareness and treatment decisions as well as how cancer awareness affects the timing of treatment decisions and the desired treatment method. Methods: This is a retrospective study that reviewed and analyzed the electronic medical records of 110 patients who were diagnosed with pancreatic cancer from ...
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Lee EJ, Seo SY, Kim IH, Kim SW, Lee SO, Lee ST, Kim SH Tags: Korean J Gastroenterol Source Type: research

A Collision Tumor of the Esophagus: Mixed Squamous Cell Carcinoma and Neuroendocrine Carcinoma.
In conclusion, patients with collision tumors must undergo active multidisciplinary management that will include pathologists and oncologists, who will decide on proper treatment strategies. PMID: 32326687 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Choe AR, Shim KN, Lim J, Song EM, Tae CH, Jung SA, Jo MS Tags: Korean J Gastroenterol Source Type: research

Mucosa-associated Lymphoid Tissue Lymphoma-mimicking Primary Gastrointestinal Small Lymphocytic Lymphoma.
Abstract Malignant lymphoma in the gastrointestinal tract is mainly secondary. Primary gastric malignant lymphoma constitutes 1-4% of gastric malignant tumors without specific endoscopic findings, and histopathologically, it is mainly classified as non-Hodgkin lymphoma of B-cell origin. Otherwise, a rare type of gastrointestinal lymphoma is small lymphocytic lymphoma (SLL). SLL is the same as a chronic lymphocytic lymphoma and tends to grow slowly. Here, we report a case of a patient diagnosed with primary gastrointestinal SLL upon endoscopy screening with non-specific mucosal findings. PMID: 32326688 [PubMed...
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Yeo SH, Jung K, Park MI, Kim SJ, Kim JH, Kim SE, Moon W, Park SJ Tags: Korean J Gastroenterol Source Type: research

Ischemic Colitis Associated with Low-volume Oral Sulfate Solution for Bowel Preparation.
Abstract Ischemic colitis resulting from bowel preparation for colonoscopy is extremely rare, with only a small number of cases with polyethylene glycol having been reported. Here, we present a patient with ischemic colitis after administration of a low-volume oral sulfate solution (OSS). A 49-year-old female without any significant medical history experienced abdominal pain, vomiting, and hematochezia after ingestion of OSS. She complained of severe abdominal pain during colonoscopy, and diffuse edema, hyperemia, friability, and shallow erosions were present on the transverse, descending, and sigmoid colons. A mu...
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Chung JW, Lee JM, Sohn YW, Han WC, Yoon K Tags: Korean J Gastroenterol Source Type: research

Acute Pancreatitis with Hypercalcemia as Initial Manifestation of Multiple Myeloma.
Abstract A case of acute pancreatitis associated with hypercalcemia resulting from a newly diagnosed multiple myeloma is reported. There have been several prior reports of hypercalcemia-induced pancreatitis in patients with multiple myeloma, but very few showed the following two aspects: pancreatitis as the first manifestation of hematologic malignancy and recovery after serum calcium levels fell into normal range. When clinicians encounter a patient with hypercalcemic status and acute pancreatitis without any known etiology of pancreatitis, multiple myeloma as a root cause of pancreatitis should be considered. ...
Source: Korean J Gastroenter... - April 25, 2020 Category: Gastroenterology Authors: Jo IH, Paik CN Tags: Korean J Gastroenterol Source Type: research

[Deep Learning in Upper Gastrointestinal Disorders: Status and Future Perspectives].
Abstract Artificial intelligence using deep learning has been applied to gastrointestinal disorders for the detection, classification, and delineation of various lesion images. With the accumulation of enormous medical records, the evolution of computation power with graphic processing units, and the widespread use of open-source libraries in large-scale machine learning processes, medical artificial intelligence is overcoming its traditional limitations. This paper explains the basic concepts of deep learning model establishment and summarizes previous studies on upper gastrointestinal disorders. The limitations ...
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Bang CS Tags: Korean J Gastroenterol Source Type: research

[Impact of Sarcopenia on the Risk of Erosive Esophagitis].
Conclusions: This study suggests that sarcopenia is strongly and progressively associated with erosive esophagitis. PMID: 32209801 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Heo CM, Kim TJ, Lee H, Pyo JH, Min YW, Min BH, Lee JH, Son HJ, Baek SY, Kim K, Ryu S, Rhee PL, Kim JJ Tags: Korean J Gastroenterol Source Type: research

Effects of Novel Probiotics in a Murine Model of Irritable Bowel Syndrome.
Conclusions: The novel probiotics have beneficial effects on defecation in a murine model of IBS. Human studies confirming the efficacy are warranted. PMID: 32209802 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Chung HG, Min YW, Lee C, Hong SN, Won JY, Jang JA, Kim CH, Chang DK Tags: Korean J Gastroenterol Source Type: research

Risk Factors for Liver Function Deterioration after Transarterial Chemoembolization Refractoriness in Child-Pugh Class A Hepatocellular Carcinoma Patients.
Conclusions: The prognostic model incorporating the tumor size, tumor number, albumin, and bilirubin at the diagnosis of HCC may help identify patients who show a poor response to TACE and aggravation of liver function after TACE, who may benefit from early switching into systemic therapy before liver function aggravation. PMID: 32209803 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Park KH, Kim JH, Choe WH, Kwon SY, Yoo BC, Hwang JH, Park SW, Kim YJ, Park HS, Yu MH, Jeon HJ Tags: Korean J Gastroenterol Source Type: research

[Phlegmonous Gastritis Caused by Penetration of a Toothpick].
Abstract Phlegmonous gastritis is a disease caused by a bacterial infection of the gastric wall. This condition is rare, but when it does occur, its prognosis appears to be poor. The underlying etiology is largely unknown, but an immunocompromised state is considered an important risk factor. An 85-year-old woman presented with a confused mentality, fever, epigastric pain, and melena. There was no history of alcohol drinking or smoking, nor of previous gastric surgery. On the other hand, there was a history of senile dementia and cognitive impairment. Initial contrast-enhanced abdominal CT revealed gastric wall ed...
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Rim CB, Kim SM Tags: Korean J Gastroenterol Source Type: research

Visceral Artery Pseudoaneurysm Rupture after Endoscopic Retrograde Cholangiopancreatography.
Abstract A visceral artery pseudoaneurysm after ERCP is a rare adverse event that is potentially life-threatening. Most cases reported previously originated from the peripancreatic arteries, including the splenic artery, gastroduodenal artery, or pancreaticoduodenal artery. The mechanism of the occurrence of visceral artery pseudoaneurysms after ERCP has not been elucidated until now. Recently, a pseudoaneurysm rupture originating from the superior mesenteric artery after ERCP was observed in a patient without a history of pancreatitis. This paper reports this case with a review of the relevant literature. PM...
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Park TY, Ryu SH, Moon JS Tags: Korean J Gastroenterol Source Type: research

Liver Graft Failure and Bile Cast Nephropathy.
Abstract The consequences of graft failure after liver transplantation (LT) range far beyond the liver. The kidneys are often affected, where persistent and progressive cholestasis can result in acute kidney injury (AKI) leading to the development of bile cast nephropathy (BCN). BCN is an often unrecognized condition that is characterized by proximal tubulopathy and the formation of bile casts in the distal tubules, which is almost diagnosed exclusively on a kidney biopsy or autopsy. This condition is potentially reversible, provided the bilirubin levels can be reduced early. LT may represent a treatment option in...
Source: Korean J Gastroenter... - March 25, 2020 Category: Gastroenterology Authors: Mrzljak A, Jurekovic Z, Novak R, Maksimovic B, Mikulic D, Ljubanovic DG Tags: Korean J Gastroenterol Source Type: research

[Optimal Laxatives for Oral Colonoscopy Bowel Preparation: from High-volume to Novel Low-volume Solutions].
Abstract Optimal bowel preparation is essential for a more accurate, comfortable, and safe colonoscopy. The majority of postcolonoscopy colorectal cancers can be explained by procedural factors, mainly missed polyps or inadequate examination. Therefore the most important goal of optimal bowel preparation is to reduce the incidence of colorectal cancer. Although adequate preparation should be achieved in 85-90% or more of all colonoscopy as a quality indicator, unfortunately 20-30% shows inadequate preparation. Laxatives for oral colonoscopy bowel preparation can be classified into polyethylene glycol (PEG)-electro...
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Na SY, Moon W Tags: Korean J Gastroenterol Source Type: research

[Optimal Bowel Preparation for Capsule Endoscopy and Device-assisted Enteroscopy].
This article reviews the literature and ESGE, 2013 Korean published guidelines regarding bowel preparation for VCE and DAE, following suggestion for optimal bowel preparation for VCE and balloon enteroscopy. PMID: 32098460 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Song HJ Tags: Korean J Gastroenterol Source Type: research

[Role of Mechanical Bowel Preparation for Elective Colorectal Surgery].
Abstract The presence of bowel contents during colorectal surgery has been related to surgical site infections (SSI), anastomotic leakage (AL) and postoperative complications theologically. Mechanical bowel preparation (MBP) for elective colorectal surgery aims to reduce fecal materials and bacterial count with the objective to decrease SSI rate, including AL. Based on many observational data, meta-analysis and multicenter randomized control trials (RTC), non-MBP did not increase AL rates or SSI and other complications in colon and even rectal surgery. In 2011 Cochrane review, there is no significant benefit MBP c...
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Kim IY Tags: Korean J Gastroenterol Source Type: research

[Preparation, Technique, and Imaging of Computed Tomography/Magnetic Resonance Enterography].
Abstract CT enterography and magnetic resonance (MR) enterography are widely used imaging modalities used to examine the small bowel. These radiologic tests are distinguished from routine abdominopelvic CT and MRI by the oral ingestion of a large amount of neutral contrast to distend the small bowel before scanning. For achievement of high quality, diagnostic images and proper technique are required. Conducted protocols still vary in patient preparation, enteric contrast, and CT and MRI acquisition sequences, resulting in heterogeneous diagnostic accuracy. The purpose of this article is to review the processes and...
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Kim MJ Tags: Korean J Gastroenterol Source Type: research

Duodenal Leiomyosarcoma Presenting with Gastrointestinal Bleeding and Obstruction: A Case Report.
We report the case of a 38-year-old man who presented with gastrointestinal bleeding and obstruction who was diagnosed with duodenal leiomyosarcoma after surgical resection. PMID: 32098463 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Hong SM, Kim GH, Kim D, Lee S Tags: Korean J Gastroenterol Source Type: research

Refractory Hepatic Hydrothorax in Chronic Hepatitis C Controlled by Direct-acting Antivirals.
We report a case of hepatic hydrothorax in a 55-year-old female patient with HCV cirrhosis, which exhibited a spontaneous decrease in pleural effusion after direct antiviral agent (DAA) therapy. In cases of HCV cirrhosis, DAAs are worth administering before treatment by TIPS or liver transplantation. PMID: 32098464 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Kim MH, Kim DK, Eun HS, Rou WS, Kim SH, Lee BS Tags: Korean J Gastroenterol Source Type: research

[Acute Acalculous Cholecystitis Associated with Sunitinib Treatment for Renal Cell Carcinoma].
Abstract A 64-year-old man was treated with sunitinib as a first-line therapy for metastatic renal cell carcinoma. He was given oral sunitinib in cycles of 50 mg once daily for 2 weeks followed by a week off. During the 5th week of treatment right upper quadrant pain developed, but this resolved spontaneously during the 6th week (off treatment). However, on the 8th week of treatment, he was admitted to hospital because the acute right upper quadrant pain recurred with nausea, vomiting, and fever. Acute acalculous cholecystitis was then diagnosed by ultrasonography and CT. In addition, his laboratory findings indic...
Source: Korean J Gastroenter... - February 25, 2020 Category: Gastroenterology Authors: Choi SW, Lee JM, Kim DG, Noh MH Tags: Korean J Gastroenterol Source Type: research

[Non-celiac Gluten Sensitivity].
Abstract Non-celiac gluten sensitivity (NCGS) is a term that is used to describe individuals who are not affected by celiac disease or wheat allergy, yet they have intestinal and/or extra-intestinal symptoms related to gluten ingestion with improvement of their symptoms upon withdrawing gluten from their diet. Gluten-related disorder groups are manifested by symptoms of gastrointestinal tract disorders, as well as hematological dermatological endocrinological, gynecological, rheumatological and nervous system symptoms. It is believed that NCGS represents heterogeneous groups with different subgroups characterized ...
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Cha RR, Kim HJ Tags: Korean J Gastroenterol Source Type: research

[Analysis of Prognosis according to Type of Health Insurance in Five Major Gastrointestinal Cancer Patients in Public Hospitals: Single-institution Retrospective Study].
Conclusions: Public hospitals have a positive effect on the treatment and prognosis in medicare group patients with the five-major GI cancers. PMID: 31986569 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Lee DS, Lee J, Kim JW, Lee KL, Kim BG, Kim SH, Jung YJ Tags: Korean J Gastroenterol Source Type: research

[Influencing Factors on Lactulose Breath Test Results].
This study aimed to identify the demographic and clinical factors associated with positive breath-test results and to assess the relationship between hydrogen and methane production in patients with suspected irritable bowel syndrome (IBS). Methods: The demographic and clinical factors of 268 patients with suspected IBS, who had undergone a lactulose breath test, were analyzed. Results: Of 268 patients included in this study, 143 (53.4%) were females. The median age and BMI of the patients was 58.0 years (range, 18.0-80.0 years) and 22.5 kg/m2 (range, 14.4-34.3 kg/m2), respectively. A weak positive correlation wa...
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Kim JW, Park SY, Chung JO, Cho HA, Kim DH, Yoon JH, Park CH, Kim HS, Choi SK, Rew JS Tags: Korean J Gastroenterol Source Type: research

Clinical Features and Outcomes of Tuberculosis in Inflammatory Bowel Disease Patients Treated with Anti-tumor Necrosis Factor Therapy.
Conclusions: The rate of extrapulmonary involvement, side effects of anti-TB medications, and clinical outcomes did not differ between the IBD patients who initially developed TB during anti-TNF therapy and non-IBD patients with TB. On the other hand, the IBD patients had a lower rate of AFB smear positivity and a higher proportion of non-respiratory symptoms. PMID: 31986571 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Kim J, Im JP, Yim JJ, Lee CK, Park DI, Eun CS, Jung SA, Shin JE, Lee KM, Cheon JH Tags: Korean J Gastroenterol Source Type: research

Effect of Sodium Cromoglycate on Acetic Acid-induced Ulcerative Colitis in Mice.
Abstract Background/Aims: Ulcerative colitis (UC) is a type of inflammatory bowel disease that mainly involves the colon. Thus far, glucocorticoids and amino-salicylate have been the main treatment. Methods: To assess drugs with fewer side effects, this study evaluated the effects of sodium cromoglycate (SCG) on acetic acid-induced UC in rats. The treatment groups included SCG receivers (50 and 100 mg/kg, intra-orally) and sulfasalazine (SSZ) receivers (100 mg/kg, intra-orally). The colonic mucosal injury was assessed by clinical, macroscopic, and histopathological examinations. Results: In the treatment...
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Ghafouri Z, Seyyedian S, Nikbakht J, Kouhsari E, Bayat S, Zargar H, Houshmand G Tags: Korean J Gastroenterol Source Type: research

Adult Ileocolic Intussusception Caused by Diffuse Large B Cell Lymphoma.
Abstract Intussusception is a medical condition, in which a proximal part of the intestine folds into the distal intestine. Adult intussusceptions are rare and account for approximately 5% of all cases of intussusceptions. The anatomical leading points include tumors, diverticulums, polyps, and strictures in 80-90% of adult intussusceptions, and 65% of colon intussusceptions and 30% of small bowel intussusceptions originate from malignant tumors. Treatments for adult intussusception have not been established, but most cases require surgical treatment. The gastrointestinal tract is the most common extranodal site f...
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Park JW, Song GA, Baek DH, Kim GH, Lee BE, Lee MW, Han SY, Park YJ, Park EY Tags: Korean J Gastroenterol Source Type: research

Palliative Measures with Ethanol Gallbladder Ablation and Endobiliary Radiofrequency Ablation Followed by Endoscopic Biliary Stent Placement in an Advanced Case of Common Bile Duct Cancer: A Case Report.
Abstract Endobiliary radiofrequency ablation (RFA) is a procedure performed widely to induce locoregional tumor control by the transfer of thermal energy to the lesion and subsequent tumor necrosis. A 72-year-old male with a prior history of acute calculous cholangitis and perforated cholecystitis was admitted to the Kyungpook National University Hospital complaining of fever and nausea. He had an indwelling percutaneous transhepatic gallbladder drainage (PTGBD) catheter from the previous episode of perforated cholecystitis. An abdominal CT scan showed marked dilation of both the intrahepatic and extrahepatic bile...
Source: Korean J Gastroenter... - January 25, 2020 Category: Gastroenterology Authors: Lee YW, Kim HJ, Lee SY, Heo J, Jung MK Tags: Korean J Gastroenterol Source Type: research

[Diagnosis and Treatment of Gastric Mucosa-associated Lymphoid Tissue Lymphoma].
Abstract The stomach is the most common primary site of an extranodal marginal zone lymphoma of mucosa-associated lymphoid tissue (MALT) type, which is characterized by an indolent clinical course. A diagnosis of gastric MALT lymphoma requires an endoscopic biopsy that should be confirmed by an experienced pathologist. Gastric MALT lymphoma shows a variable endoscopic appearance, including erosion, erythema, discoloration, atrophy, ulcer, and subepithelial lesion. The distribution is often multifocal. Therefore, clinical suspicion and multiple biopsies are essential for an accurate diagnosis. Gastric MALT lymphoma...
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Gong EJ, Choi KD Tags: Korean J Gastroenterol Source Type: research

Role of Gut Microbiota in Type 2 Diabetes Mellitus and Its Complications: Novel Insights and Potential Intervention Strategies.
Abstract Type 2 diabetes mellitus has become one of the fastest growing public health problems worldwide. The disease is believed to involve a complex process involving genetic susceptibility and environmental factors. The human intestine harbors hundreds of trillions of bacteria, as well as bacteriophage particles, viruses, fungi, and archaea, which constitute a complex and dynamic ecosystem referred to as the gut microbiota. Increasing evidence has indicated changes in the gut microbiota composition or function in type 2 diabetic patients. An analysis of 'dysbiosis' enables the detection of alterations in the sp...
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Woldeamlak B, Yirdaw K, Biadgo B Tags: Korean J Gastroenterol Source Type: research

Risk of Delayed Bleeding after a Colorectal Endoscopic Mucosal Resection without Prophylactic Clipping: Single Center, Observational Study.
Abstract Background/Aims: Bleeding is one of the major complications of a colorectal polypectomy. The aim of this study was to identify the risk of delayed bleeding, particularly after a colorectal endoscopic mucosal resection (EMR) without prophylactic clipping. Methods: Between April 2014 and August 2014, patients who underwent colorectal EMR (≥6 mm and
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Kim H, Kim JH, Choi YJ, Kwon HJ, Chang HK, Kim SE, Moon W, Park MI, Park SJ Tags: Korean J Gastroenterol Source Type: research

Knowledge and Viewpoints on Biosimilar Monoclonal Antibodies among Asian Physicians: Comparison with European Physicians.
Conclusions: Asian gastroenterologists in 2017 are generally well informed about biosimilars. On the other hand, compared to the ECCO members surveyed in 2015, Asian gastroenterologists had more concerns and less confidence about the use of biosimilars in clinical practice. Thus, IBD-specific data on the comparison of the efficacy, safety, and immunogenicity in Asian patients are needed. PMID: 31870139 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Park SK, Moon W, Kim ES, Park SH, Park DI Tags: Korean J Gastroenterol Source Type: research

Diagnostic Performance of Serum Asialo- α1-acid Glycoprotein for Advanced Liver Fibrosis or Cirrhosis in Patients with Chronic Hepatitis B or Nonalcoholic Fatty Liver Disease.
Conclusions: The AsAGP level showed acceptable diagnostic accuracy in predicting advanced liver fibrosis and cirrhosis in patients with CHB but not in those with NAFLD. Further studies will be needed to validate the diagnostic performance of the AsAGP level in patients with NALFD. PMID: 31870140 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Kim SU, Jeon MY, Lim TS Tags: Korean J Gastroenterol Source Type: research

[Mixed Neuroendocrine-non-neuroendocrine Neoplasm of the Stomach that is Distributed in Depth on the Same Tumor: Inconsistent with the Definition of Mixed Adenoneuroendocrine Carcinoma in the 2010 World Health Organization Classification of Tumors of the Digestive System].
Abstract A mixed adenoneuroendocrine carcinoma (MANEC) of the stomach is a rare disease entity that was first defined by the World Health Organization (WHO) classification (2010) for tumors of the digestive system. According to the WHO classification (2010), MANEC is referred to as a tumor with both neuroendocrine and non-neuroendocrine neoplasms; each component of the tumor should be at least 30%. On the other hand, this cut-off value lacks clinical evidence and does not explain the characteristics and heterogeneity of this tumor. A 66-year-old male diagnosed with early gastric cancer (EGC) at a community hospita...
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Jeong J, Jung K, Kim JH, Kim SE, Moon W, Park MI, Park SJ Tags: Korean J Gastroenterol Source Type: research

Magnetic Resonance Imaging Findings of Biliary Adenofibroma.
Abstract Biliary adenofibroma is a rare tumor with a bile duct origin characterized by a complex tubulocystic non-mucin secreting biliary epithelium with abundant fibrous stroma. The MRI features of biliary adenofibroma are not well established. The authors encountered two patients with biliary adenofibroma and reviewed the literature focusing on the MRI findings. A well-circumscribed multicystic tumor with septal enhancement and no intrahepatic bile duct communication may be the characteristic MRI findings of biliary adenofibroma. PMID: 31870142 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - December 25, 2019 Category: Gastroenterology Authors: Lee S, Kim KW, Jeong WK, Yu E, Jang KT Tags: Korean J Gastroenterol Source Type: research