Changes in the Crohn's Disease Activity Index and Safety of Administering Saccharomyces Boulardii in Patients with Crohn's Disease in Clinical Remission: A Single Hospital-based Retrospective Cohort Study.
This study examined the changes in the CD activity index (CDAI) after taking S. boulardii in patients with CD in clinical remission. Methods: In this single hospital-based retrospective cohort study, the medical records of CD patients in clinical remission, who had received S. boulardii for more than 6 months, were reviewed. The CDAI, BMI, and serum levels of hemoglobin (Hb), ferritin, iron, vitamin B12, folate, total protein, albumin, total cholesterol, CRP, and fecal calprotectin (FC) between the initiation and the 6th month were compared. The timing and reasons for the discontinuation were also investigated. R...
Source: Korean J Gastroenter... - November 30, 2020 Category: Gastroenterology Authors: Oh GM, Moon W, Seo KI, Jung K, Kim JH, Kim SE, Park MI, Park SJ Tags: Korean J Gastroenterol Source Type: research

Helicobacter pylori Eradication in Drug-related Peptic Ulcer.
Abstract Non-steroidal anti-inflammatory drugs (NSAIDs) and aspirin are the most frequently prescribed drugs worldwide, and their long-term use often leads to peptic ulcers (PUs) along with serious complications, such as bleeding and perforation. Helicobacter pylori (H. pylori) infection is a significant risk factor for developing NSAID-related PU and ulcer bleeding during long-term aspirin use. In a revised version of the Clinical Guidelines for Drug-induced Peptic Ulcer, two statements regarding H. pylori eradication are recommended. 1) Patients scheduled for long-term NSAID therapy should be tested and treated ...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Joo MK Tags: Korean J Gastroenterol Source Type: research

Prevention of Non-steroidal Anti-inflammatory Drug-induced Peptic Ulcers.
Abstract Nonsteroidal anti-inflammatory drugs (NSAID) are some of the most commonly prescribed medications in clinical practice. The long-term use of NSAIDs is one of the main causes of peptic ulcers and the increased risk of upper gastrointestinal tract complications, such as perforation and bleeding. Thus, the prevention of NSAID-induced peptic ulcers is an important clinical issue. Previous studies have evaluated various strategies for preventing ulcers in patients requiring prolonged NSAID use. The Korean clinical practice guidelines have been published recently based on the evidence of the currently available...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Chu SJ, Yoon KT, Kim JS Tags: Korean J Gastroenterol Source Type: research

Prevention of Peptic Ulcer Associated with Aspirin and Antiplatelet Agent.
Abstract The Korean guidelines for the Clinical Guidelines for Drug-related Peptic Ulcer were revised under the Korean College of Helicobacter and Upper Gastrointestinal Research in 2020. In these revised guidelines, treatment for Helicobacter pylori infections is recommended in patients with a history of peptic ulcers and are receiving long-term low-dose aspirin therapy to prevent peptic ulcers and complications. The maintenance of anti-ulcer drugs, such as proton pump inhibitors, is also recommended after H. pylori eradication if patients require other antiplatelet agents or anticoagulants. Regardless of H. pylo...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Ahn JY Tags: Korean J Gastroenterol Source Type: research

Management of Peptic Ulcer Bleeding in Patients Taking Aspirin or Anticoagulant.
Abstract Antiplatelet and anticoagulation agents are increasingly prescribed for secondary prophylaxis in patients with cardiovascular and cerebrovascular diseases. These drugs are associated with an increased risk of gastrointestinal bleeding, including peptic ulcer bleeding. It is difficult to decide when to restart the agents after peptic ulcer bleeding in these patients because the risk of rebleeding and thromboembolism should be balanced. The Korean College of Helicobacter and Upper Gastrointestinal Research revised the guidelines for drug-induced peptic ulcers as evidence-based guidelines using a de novo pro...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Yang HJ Tags: Korean J Gastroenterol Source Type: research

Hemoperitoneum with Splenic Artery Rupture Following Diagnostic Colonoscopy.
Abstract Colonoscopy is a safe and extremely popular diagnostic and therapeutic procedure. The most common complications are bleeding and perforation. Hemoperitoneum is a rare complication after a colonoscopy and is usually associated with splenic injury or solid organ pathology. This is potentially serious and can be life threatening. With the increasing number of colonoscopies performed, there has also been an increasing trend in reports of rare complications, such as pneumothorax, pneumomediastinum, appendicitis, small bowel perforation, septicemia, mesenteric tear, retroperitoneal abscess, and hemoperitoneum. ...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Kang YW, Lee JY, Lee JH Tags: Korean J Gastroenterol Source Type: research

Low-grade Rectal Neuroendocrine Tumor Recurring as Multiple Hepatic Metastasis after Complete Endoscopic Removal: A Case Report.
Abstract The World Health Organization classified rectal neuroendocrine tumors (NETs) as malignant in 2010 owing to their distant metastasis potential. On the other hand, in cases of small rectal NETs (
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Jo IH, Lee KM, Kim DB, Lee JM Tags: Korean J Gastroenterol Source Type: research

Seroreversion and Acute Decompensation in Chronic Hepatitis B after Discontinuation of Oral Nucleotide Analog in the Patients Achieving HBsAg Loss.
Abstract Although rare patients with chronic hepatitis B can achieve HBsAg loss on oral nucleos(t)ide analog (NA), the optimal timing of stopping oral NAs safely has been considered when HBsAg and HBV DNA are negative in the serum because HBsAg loss induced by nucleos(t)ide analogs (NAs) appears to be durable if immunosuppressive therapy or chemotherapy are not done. On the other hand, the author experienced a case of HBsAg seroreversion and acute decompensation after the discontinuation of NA in a patient with HBsAg loss. This rare case highlights the need for the close monitoring of patients who achieved HBsAg l...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Cho HJ, Shin SK, Kwon OS, Kim JH, Kim YS Tags: Korean J Gastroenterol Source Type: research

Oxaliplatin-induced Sudden Hearing Loss in a Patient with Pancreatic Cancer.
Abstract Oxaliplatin is a new generation of platinum derivatives used frequently to treat solid organ malignancies, including colorectal and ovarian cancer. Recently, an oxaliplatin-based chemotherapeutic regimen was adopted for advanced pancreatic cancer. Although oxaliplatin has extensive therapeutic potential, its use can be limited by significant adverse effects, particularly ototoxicity. This paper reports a rare case of irreversible unilateral hearing loss in a 48-year-old female that developed after the intravenous infusion of oxaliplatin during pancreatic cancer treatment. To the best of the authors' knowl...
Source: Korean J Gastroenter... - November 25, 2020 Category: Gastroenterology Authors: Kim SB, Kim SY, Kim KH, Kim TN Tags: Korean J Gastroenterol Source Type: research

Clinical Outcomes of Mucinous Gastric Carcinomas Compared with Non-mucinous and Signet Ring Cell Carcinomas.
This study examined the clinical features and prognosis of patients with mucinous gastric carcinoma (MGC), non-mucinous gastric carcinoma (NMGC), and signet ring cell gastric carcinoma (SRC). Methods: A retrospective cohort study was performed, enrolling 65 patients with MGC from January 2007 to December 2016. During the same period, 1,814 patients with histologically proven gastric cancers underwent curative or palliative operations. One hundred and ninety-five NMGC patients were selected as the 1:3 age- and sex-matched control groups. In addition, 200 SRC patients were identified. This study evaluated the demographi...
Source: Korean J Gastroenter... - November 17, 2020 Category: Gastroenterology Authors: Ahn H, Chung WC, Kim YJ, Ryu S, Lim E Tags: Korean J Gastroenterol Source Type: research

Diagnostic Approach for Esophagogastric Junction Outflow Obstruction.
Abstract Esophageal manometry is the gold standard test for diagnosing primary esophageal motility disorder. With the various metrics of the high-resolution esophageal manometry, the Chicago classification provides a standard approach for the manometric diagnosis of esophageal motor disorders. In the Chicago classification, the esophagogastric junction dysfunction is an important major motor disorder, which includes achalasia subtypes and esophagogastric junction outflow obstruction. Esophagogastric junction outflow obstruction is defined manometrically as normal or weak esophageal peristalsis with incomplete rela...
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Cho YK Tags: Korean J Gastroenterol Source Type: research

Association between Inflammatory Bowel Disease and Lactose Intolerance: Fact or Fiction.
This study examined the association between lactose intolerance (LI) and IBD. Methods: Data on hospital admissions of all IBD adult patients were extracted from the National Inpatient Sample database between 2004 and 2014. The comorbidities and outcomes of interest were defined by querying all the diagnostic and procedural fields for the corresponding International Classification of Diseases 9th version (ICD-9) codes. Patients with IBD were defined as the "study group," and the patients who did not have IBD were defined as the "control group". LI was identified in both groups using the ICD-9 codes....
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Asfari MM, Sarmini MT, Kendrick K, Hudgi A, Uy P, Sridhar S, Sifuentes H Tags: Korean J Gastroenterol Source Type: research

Prognostic Factors of Patients with Stercoral Perforation of the Colon.
Conclusions: Preoperative abnormal serum lactate levels may be a risk factor for mortality after surgery in patients with stercoral perforation. Further research will be needed to identify the postoperative prognostic SPC factors. PMID: 33100314 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Lee HJ, Kim KH, Lee SC, Song S Tags: Korean J Gastroenterol Source Type: research

Clinical Impact of Common Bile Duct Angulation on the Recurrence of Common Bile Duct Stone: A Meta-analysis and Review.
Abstract Background/Aims: Local and systemic factors, such as diabetes, obesity, and hyperlipidemia, are considered risk factors for the recurrence of choledocholithiasis after successful endoscopic clearance. Local factors include the presence of bile sludge, common bile duct (CBD) diameter, and CBD angulation. Among them, it is unclear if acute CBD angulation is preferable to the recurrence of a CBD stone. Methods: PubMed, EMBASE, CINAHL, the Cochrane Library databases, and google website were searched for randomized controlled trials reported in English and undertaken until August 2019. Meta-analysis was p...
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Ryu S, Jo IH, Kim S, Kim YJ, Chung WC Tags: Korean J Gastroenterol Source Type: research

Gastric Gastrointestinal Stromal Tumor with Repeated Recurrence at the Anastomosis Site in a Very Elderly Patient.
Abstract Although high-risk gastrointestinal stromal tumors (GISTs) frequently recur, even after a complete resection and imatinib therapy, local recurrence at the suture line after complete resection is rare. The present case was an 88-year-old woman who was initially diagnosed with high-risk GIST without a distant metastasis. She underwent a complete surgical resection of the lesion and received adjuvant imatinib therapy for 18 months, which was discontinued due to severe drug-induced anemia. During the follow- up, an endoscopic examination performed 40 months after the initial surgery revealed local recurrence ...
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Kim HJ, Park JY, Kim BJ, Kim JG, Kim HS, Park JM Tags: Korean J Gastroenterol Source Type: research

Acute Pancreatitis associated with Acute Hepatitis A in an Old Aged Patient.
Abstract Acute pancreatitis caused by acute hepatitis A is extremely rare, with only a small number of cases in young adults having been reported. This paper presents a 74-year-old female patient with an acute abdomen, which proved to be acute pancreatitis with acute hepatitis A. A survey of acute viral hepatitis A as a root cause of pancreatitis should be considered when clinicians encounter patients with acute pancreatitis without any known etiology of pancreatitis. PMID: 33100317 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Hong K, Paik CN, Jo IH, Kim DB Tags: Korean J Gastroenterol Source Type: research

Removal of a Large, Intractable Common Bile Duct Stone by Direct Peroral Cholangioscopy Using Upper Gastrointestinal Endoscopy and Polypectomy Snare.
Abstract ERCP is the standard treatment for common bile duct stones. On the other hand, 10-15% of cases involve intractable common bile duct stones, which cannot be treated by conventional biliary sphincterotomy with a stone retrieval method. Large bile duct stones are typically managed by mechanical lithotripsy and endoscopic papillary large balloon dilatation. Peroral cholangioscopy techniques can be applied if this technique fails. In the present case, a 67-year-old woman had a large common bile duct stone that could not be retracted using the conventional ERCP stone extraction method. The common bile duct ston...
Source: Korean J Gastroenter... - October 25, 2020 Category: Gastroenterology Authors: Heo J, Jung MK Tags: Korean J Gastroenterol Source Type: research

[Recent Updates on Diagnosis, Treatment, and Follow-up of Gallbladder Polyps].
Abstract A gallbladder (GB) polyp is an elevation of the GB mucosa that protrudes into the GB lumen. GB polyps have an estimated prevalence of 0.3-9.5% and can be divided into neoplastic (true) polyps and nonneoplastic polyps (pseudopolyps). Pseudopolyps are most commonly cholesterol polyps but also include focal adenomyomatosis and inflammatory polyps with no malignant potential. Neoplastic polyps, however, can be benign or malignant. Benign polyps are most commonly adenomas, while malignant polyps are usually adenocarcinoma. Transabdominal ultrasonography is the main radiological modality used for diagnosing and...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Jang SI, Cho JH, Lee DK Tags: Korean J Gastroenterol Source Type: research

[Clinical Guidelines for Drug-induced Peptic Ulcer, 2020 Revised Edition].
In this study, a guideline development committee for drug-induced peptic ulcers was organized under the Korean College of Helicobacter and Upper Gastrointestinal Research in 2017. Nine statements were developed, including four for NSAID, three for aspirin and other antiplatelet agents, and two for anticoagulants through de novo processes based on evidence-based medicine, such as a literature search, meta-analysis, and the consensus was established using the modified Delphi method. The primary target of this guideline was adult patients taking long-term NSAIDs, aspirin, or other antiplatelet agent and anticoagulants. The re...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Joo MK, Park CH, Kim JS, Park JM, Ahn JY, Lee BE, Lee JH, Yang HJ, Cho YK, Bang CS, Kim BJ, Jung HK, Kim BW, Lee YC, Korean College of Helicobacter and Upper Gastrointestinal Research Tags: Korean J Gastroenterol Source Type: research

Endoscopic Prediction for Acid Reflux in Patients without Hiatus Hernia.
This study examined the predictive role of the endoscopic findings, including the flap valve grade for pathologic acid exposure (PAE) to establish an endoscopic prediction model in patients with neither reflux esophagitis nor HH. Methods: Five hundred seventy-eight patients who underwent upper endoscopy and 24 hours pH monitoring for reflux esophageal symptoms without evidence of reflux esophagitis and HH were analyzed. The gastroesophageal flap valve (GEFV), esophageal metaplasia, and chronic atrophic gastritis were assessed. The association between the endoscopic parameters and PAE was evaluated. Results: Four ...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Kim JY, Shin IS, Min YW, Kim K, Lee H, Min BH, Lee JH, Kim JJ, Rhee PL Tags: Korean J Gastroenterol Source Type: research

Efficacy of Seven-day High-dose Esomeprazole-based Triple Therapy versus Seven-day Standard Dose Non-esomeprazole-based Triple Therapy as the First-line Treatment of Patients with Helicobacter pylori Infection.
Conclusions: The eradication rate of the 7-HEAC group was higher than that of the 7-NEAC group. Nevertheless, more effective first-line therapies may be necessary for H. pylori eradication in the near future. PMID: 32969362 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Lee YD, Kim SE, Park SJ, Park MI, Moon W, Kim JH, Jung K, Song J Tags: Korean J Gastroenterol Source Type: research

Arthrospira (Spirulina) platensis Attenuates Dextran Sulfate Sodium-induced Colitis in Mice by Suppressing Key Pro-inflammatory Cytokines.
Conclusions: SPI may be an alternative source of bioactive molecules with immunomodulatory properties, and has great potential to be used in the treatment of inflammatory diseases. PMID: 32969363 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Garcia FAO, Sales-Campos H, Yuen VG, Machado JR, Viana GSB, Oliveira CJF, McNeill JH Tags: Korean J Gastroenterol Source Type: research

Serrated Polyposis Syndrome with a Synchronous Colon Adenocarcinoma Treated by an Endoscopic Mucosal Resection.
Abstract Serrated polyposis syndrome (SPS) can transform to malignant lesions through the sessile serrated pathway and traditional serrated pathway. These pathways may cause rapid neoplastic progression compared to the adenoma-carcinoma sequence, which may cause interval colorectal cancer. The authors experienced a case of SPS with a synchronous colon adenocarcinoma that was treated with an endoscopic mucosal resection. In pathology reviews, other parts of the adenocarcinoma showed sessile serrated adenoma. Therefore, patients with SPS have a potential for malignant transformation, highlighting the need for strict...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Lee SH, Lee SJ, Park SC, Nam SJ, Kang MH, Kim TS, Lee SK Tags: Korean J Gastroenterol Source Type: research

Acute Intestinal Ischemia in a Patient with COVID-19 Infection.
Abstract The World Health Organization has declared novel coronavirus disease 2019 (COVID-19) a global public health emergency. Although respiratory symptoms predominate in COVID-19, thrombosis can occur in patients with COVID-19. This paper reports a case of an 82-year-old female with a prior medical history of hypertension, diabetes presenting with fever and cough, and was diagnosed with COVID-19. The patient subsequently developed progressively worsening of abdominal distention, tenderness, and underwent emergent laparotomy. She was found to have a gangrenous colon. This case adds to the limited literature rega...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Singh B, Mechineni A, Kaur P, Ajdir N, Maroules M, Shamoon F, Bikkina M Tags: Korean J Gastroenterol Source Type: research

Severe Persistent Jaundice after the Abuse of an Anabolic Androgenic Steroid Analogue.
Abstract Hepatic disorders with prominent cholestasis can be caused by a range of conditions, and anabolic androgenic steroids have been considered a cause of protracted cholestasis. A 29-year-old man who had taken an anabolic androgenic steroid analogue for 2 months visited the hospital complaining of jaundice and indigestion. After stopping the medication, the hyperbilirubinemia tended to decrease, but a transiently elevated aminotransferase level was observed. The endogenous testosterone level also decreased initially but recovered soon after. The liver function profiles were normalized after 2 months of conser...
Source: Korean J Gastroenter... - September 24, 2020 Category: Gastroenterology Authors: Goh HG, Lee YJ, Kim TH Tags: Korean J Gastroenterol Source Type: research

[Epidemiology of Alcoholic Liver Disease in Korea].
Abstract The harmful use of alcohol is associated with significant medical and socioeconomic burdens responsible for approximately 6% of all deaths worldwide. In Korea, the total alcohol consumption recently decreased slightly from 14.8 L of alcohol per person on average in 2011 to 9.1 L in 2015. On the other hand, over the past 10 years (2007-2017), the rates of monthly alcohol consumption, which is defined as drinking more than once a month, and the rates of high-risk alcohol consumption, defined as drinking more than seven standard drinks twice a week or more, have increased. In particular, the death rate due t...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Lee SW Tags: Korean J Gastroenterol Source Type: research

[Diagnosis and Severity Assessment of Alcohol-Related Liver Disease].
Abstract A diagnosis of alcohol-related liver disease (ALD) requires information on the history of excessive alcohol consumption (average intake of 40 g or more in men and 20 g or more in women a day). Furthermore, blood tests, such as GGT, AST, ALT, and mean corpuscular volume, and imaging studies, including abdominal ultrasound or transient elastography, are also useful. A liver biopsy can be useful for confirming the diagnosis and has prognostic value. ALD includes alcoholic fatty liver, alcoholic hepatitis, and alcoholic cirrhosis, and in most cases, clinical manifestations can overlap. The prognostic scoring ...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Kim E, Park SH Tags: Korean J Gastroenterol Source Type: research

[Medical Treatment of Alcoholic Liver Disease].
Abstract Alcoholic liver disease is a major cause of liver disease that results in significant morbidity and mortality in Korea. Abstinence is the most important strategy to prevent disease progression. Corticosteroids improve the one-month survival in patients with severe alcoholic hepatitis, but it was not effective on long-term survival. An N-acetylcysteine treatment combined with corticosteroids may provide a short-term survival benefit than corticosteroids alone. Pentoxifylline is unlikely to affect short-term survival. Hence, studies on new therapies, such as granulocyte colony-stimulating factor and fecal m...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Song DS Tags: Korean J Gastroenterol Source Type: research

[Assessment and Treatment of Alcohol Withdrawal Syndrome].
Abstract Alcohol withdrawal syndrome (AWS) is the most common and well-known condition occurring after intentional or unintentional cessation or decreasing heavy drinking. Approximately 5-10% of these people are suffering from serious medical and psychiatric problems, withdrawal seizures, perceptual disturbances, and delirium tremens. Despite acute medical conditions with the high mortality of severe AWS, proper management could decrease the severity and mortality of AWS. The Clinical Institute withdrawal assessment for alcohol-revised version is a valid, reliable, and sensitive instrument for assessing the clinic...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Choi HY, Seo JS, Lee SK Tags: Korean J Gastroenterol Source Type: research

Eosinophilic Esophagitis with Angina Pectoris.
Abstract Eosinophilic esophagitis (EoE) is an immune or antigen-mediated chronic inflammatory esophageal disorder that is relatively rare in Asian countries. The main symptoms of EoE are dysphagia and food impaction. Although chest pain is a symptom of EoE, it is also a symptom of coronary heart disease. This paper reports a case of EoE with angina pectoris in a 45-year-old male who was referred to the authors' hospital for chest pain. He was diagnosed with angina pectoris because of mild stenosis in the left coronary artery on coronary angiography. On the other hand, the symptoms did not improve with angina medic...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Son MY, Kim SE, Park SJ, Park MI, Moon W, Kim JH, Jung K, Choi GS, Im SI Tags: Korean J Gastroenterol Source Type: research

[Pneumothorax Following Gastric Endoscopic Mucosal Resection].
Abstract An endoscopic mucosal resection (EMR) is used widely as an alternative treatment to a surgical resection for early gastric neoplastic lesions. Among the unusual complications of gastric EMR, perforation is usually manifested as a pneumoperitoneum. This paper reports a patient with a left-side pneumothorax without pneumoperitoneum as a complication of gastric EMR. The patient developed a left side pneumothorax after gastric EMR in the gastric fundus and recovered without further complications after conservative treatment, including endoscopic clipping. PMID: 32839371 [PubMed - in process] (Source: Kor...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Koh M, Jang JS, Cha JH Tags: Korean J Gastroenterol Source Type: research

Primary Epiploic Appendagitis Mimicking Acute Appendicitis: A Case Report and Narrative Review of the Literature.
We report a 42-year-old male who appeared in the morning in the emergency department with abdominal pain localized in the right lower abdomen and associated with anorexia and nausea. Clinical examination, laboratory tests, and abdominal ultrasound revealed deep tenderness at Mc Burney point and a mild elevation of CRP (0.7 mg/dL). In the evening, the symptoms were exacerbated, and a diagnostic laparoscopy was performed. Intra-operatively, the appendix was normal and a twisted, necrotic epiploic appendage originating from the antimesenteric border of the mid ascending colon was found. Laparoscopic resection of the necrotic ...
Source: Korean J Gastroenter... - August 24, 2020 Category: Gastroenterology Authors: Kefala MA, Tepelenis K, Stefanou CK, Stefanou SK, Papathanakos G, Kitsouli A, Tepelenis N, Kitsoulis P Tags: Korean J Gastroenterol Source Type: research

COVID-19 from the Perspective of a Gastroenterologist.
Abstract The World Health Organization (WHO) declared the worldwide pandemic of Coronavirus disease-2019 (COVID-19) On March 11, 2020, just three months after the first outbreak of COVID-19 caused by Severe Acute Respiratory Syndrome Coronavirus 2 in China in December 2019. COVID-19 is a contagious disease that can affect anyone, anytime, anywhere, and has had a huge impact on our lives, including social, economic, educational, and cultural life. In this paper, I would like to explore the issues related to COVID-19 in the gastroenterology and share the experiences of domestic and overseas gastroenterologists, and ...
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Boo SJ Tags: Korean J Gastroenterol Source Type: research

Endoscopic and Endosonographic Features of Histologically Proven Gastric Ectopic Pancreas by Endoscopic Resection.
Conclusions: EUS can help identify the features of GEP. Careful observations of the EUS findings can avoid unnecessary removal of GEP. PMID: 32703915 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Lee HS, Kim DH, Park SY, Kim S, Kim GT, Cho E, Yoon JH, Park CH, Kim HS, Choi SK, Kim NI, Rew JS Tags: Korean J Gastroenterol Source Type: research

Survival Benefit of Palliative Primary Tumor Resection Based on Tumor Location in Patients with Metastatic Colorectal Cancer: A Single-center Retrospective Study.
Conclusions: The primary tumor location influences the prognosis, and that a primary tumor resection can improve the overall survival in patients with metastatic CRC, regardless of the primary tumor location. PMID: 32703916 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Kim JH, Jin S, Jeon MJ, Jung HY, Byun S, Jung K, Kim SE, Moon W, Park MI, Park SJ Tags: Korean J Gastroenterol Source Type: research

Current Status of Amebic Liver Abscess in Korea Comparing with Pyogenic Liver Abscess.
Conclusions: Amebic liver abscess should still be considered as one of the causes of liver abscess in Korea. It is difficult to discriminate an amebic liver abscess from a pyogenic liver abscess only according to the clinical, laboratory, and radiologic findings. Therefore, it is necessary to perform a serologic test for E. histolytica for a precise evaluation of liver abscess in a high-risk group. PMID: 32703917 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Kim E, Park DH, Kim KJ, Kim TO, Park SH, Park J, Choi JH, Lee J, Park YE, Oh EH, Hwang JS, Heo NY Tags: Korean J Gastroenterol Source Type: research

Gastric Adenocarcinoma Arising from Heterotopic Pancreas Presenting as Gastric Outlet Obstruction 10 Years after the First Diagnosis.
Abstract Gastric heterotopic pancreas is a relatively uncommon incidental finding. On the other hand, the presentation of gastric adenocarcinoma arising from a heterotopic pancreas is rare. This paper reports a case of gastric adenocarcinoma arising from a heterotopic pancreas that presented as a gastric outlet obstruction 10 years after the initial diagnosis of a suspicious submucosal tumor. Endoscopy revealed a pyloric stricture with prepyloric wall thickening and a complete gastric outlet obstruction. Abdominal and pelvic computed tomography exposed a severely distended gastric lumen at the antrum with heteroge...
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Jung HS, Lee J, Nam KH, Jeong SJ, Oh EH, Park YE, Park J, Kim TO Tags: Korean J Gastroenterol Source Type: research

Endoscopy-assisted Removal of a Large Rectal Foreign Body by the Valsalva Maneuver.
Abstract Although not as common as foreign bodies in the upper gastrointestinal tract, rectal foreign body insertion is often encountered in emergency departments. The diverse types of rectal foreign bodies have led to various removal methods. When removing a foreign body, the first thing to consider is which method is the least invasive and safest for the patient. This paper reports the successful removal of a rectal foreign body from the rectum using the Valsalva maneuver without anesthesia in a patient. PMID: 32703919 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Son MY, Park SJ, Moon W, Oh GM, Park MI, Kim SE, Kim JH, Jung K Tags: Korean J Gastroenterol Source Type: research

Pancreatic Hemangioma Suspected of Neuroendocrine Tumor.
In this report, a 61-year-old woman presented with melena and showed multiple small hyper-vascular lesions in the pancreas. A pancreatic neuroendocrine tumor was suspected, and the patient underwent a distal pancreatectomy. The pathology examination and immunohistochemical study revealed a pancreatic hemangioma. PMID: 32703920 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - July 24, 2020 Category: Gastroenterology Authors: Jeong MA, Lee JK, Nam JH, Jang DK, Lim YJ, Lee JJ, Kim EJ Tags: Korean J Gastroenterol Source Type: research

[Post-colonoscopy Colorectal Cancer: Causes and Prevention of Interval Colorectal Cancer].
Abstract Colorectal cancer (CRC) is the third most commonly diagnosed cancer and the fourth leading cause of cancer death in the worldwide. Colonoscopy is the gold standard for screening and surveillance of CRC. Removing adenomas by colonoscopy has lowered the incidence and mortality of CRC. However, colonoscopy is imperfect for detection of colorectal neoplasia. After a colonoscopy that is negative for malignancy, CRC can be diagnosed. These are termed as post-colonoscopy CRC (PCCRC). The proportion of PCCRC, among all CRC was reported to be 1.8% to 9.0%. It occurred 2.4 times more in the right colon than in the ...
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Lee JY, Lee JH Tags: Korean J Gastroenterol Source Type: research

[Guidelines for Non-variceal Upper Gastrointestinal Bleeding].
Abstract Non-variceal upper gastrointestinal bleeding (NVUGIB) refers to bleeding that develops in the gastrointestinal tract proximal to the ligament of Treitz. NVUGIB is an important cause for visiting the hospital and is associated with significant morbidity and mortality. Although European and Asian-Pacific guidelines have been published, there has been no previous guidelines regarding management of NVUGIB in Korea. Korea is a country with a high prevalence of Helicobacter pylori infection and patients have easy accessibility to receive endoscopy. Therefore, we believe that guidelines regarding management of N...
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Kim JS, Kim BW, Kim DH, Park CH, Lee H, Joo MK, Jung DH, Chung JW, Choi HS, Baik GH, Lee JH, Song KY, Hur S Tags: Korean J Gastroenterol Source Type: research

[Therapeutic Response to 20 mg of Esomeprazole Twice Daily in Patients with Gastroesophageal Reflux Disease-related Non-cardiac Chest Pain: An Open-Label Randomized Pilot Study].
Conclusions: Esomeprazole BD was as effective as esomeprazole OD in improving GERD-related NCCP. Although statistically insignificant, the percentage of patients with>50% reduction in the chest pain score was higher in the esomeprazole BD group than in the esomeprazole OD group. Large-scale studies will be needed to assess these findings further. PMID: 32581204 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Choi JK, Shim HI, Shin CM, Yoon H, Park YS, Kim N, Lee DH Tags: Korean J Gastroenterol Source Type: research

Usefulness and Complications of Needle Knife Fistulotomy as a Rescue Procedure in Patients with Pancreaticobiliary Disease.
Conclusions: NKF is an effective and safe method that can be considered for rescue management after the initial failure of standard cannulation or DGT. NKF following standard cannulation can be preferred over NKF following DGT because of the higher success rate and the lower rate of pancreatitis, but the difference was not significant. PD stenting in patients at high risk of PEP can be considered to decrease pancreatitis. PMID: 32581205 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Lee YJ, Kang DH, Kim HW, Park SB, Kim SJ, Nam HS, Ryu DG Tags: Korean J Gastroenterol Source Type: research

[Post-meningitis Dumping Syndrome: A Case Report and Literature Review].
Abstract Dumping syndrome has long been associated with gastric surgery. The authors experienced an adult patient presenting with dumping syndrome after meningitis without any previous surgical procedures on the stomach and small bowel. Dysfunction of the autonomic nervous system after infective meningitis may originate from postinfectious sequelae or an immunologic mechanism. A comprehensive study and proper management of autonomic symptoms of patients with a central nervous system infection are needed. PMID: 32581206 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Park JH, Park YE, Kang MR Tags: Korean J Gastroenterol Source Type: research

[Gallbladder Perforation after Transarterial Chemoembolization in a Patient with a Huge Hepatocellular Carcinoma].
Abstract Transarterial chemoembolization (TACE) is a common treatment for unresectable hepatocellular carcinoma (HCC). The most common complications after TACE are non-specific symptoms called post-embolization syndrome, such as abdominal pain or fever. Rare complications, such as liver failure, liver abscess, sepsis, pulmonary embolism, cholecystitis, can also occur. On the other hand, gallbladder perforation is quite rare. This paper reports a case of gallbladder perforation following TACE. A 76-year-old male with a single 9-cm-sized HCC underwent TACE. Five days after TACE, he developed persistent right upper q...
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Son MY, Han BH, Lee SU, Yun BC, Seo KI, Huh JD Tags: Korean J Gastroenterol Source Type: research

Metachronous Development of Peritoneal Carcinomatosis in a Patient with Autoimmune Pancreatitis.
Abstract Autoimmune pancreatitis (AIP) is a rare and unique type of chronic pancreatitis. The prognosis of AIP, particularly when associated with pancreatic cancer or a related malignancy, is not known. Only a few cases, where metachronous pancreas-related cancer developed during follow-up, have been reported. Most of these patients either underwent surgery or steroid therapy. This paper reports a case of a 66-year-old woman with untreated type I AIP who developed peritoneal carcinomatosis more than 2 years later. Initially, the patient had a markedly elevated serum IgG4 level and a diffuse, infiltrative mass-like...
Source: Korean J Gastroenter... - June 24, 2020 Category: Gastroenterology Authors: Lee KW, Chang JH, Kim J, Kim TH, Kim CW, Kim JK, Han SW Tags: Korean J Gastroenterol Source Type: research

[Gut Microbiota and Pancreatobiliary System].
Abstract The gut microbiota is part of the human body that is involved in body metabolism and the occurrence of various diseases. Detecting and analyzing their genetic information (microbiome) is as important as analyzing human genes. The core microbiome, the key functional genes shared by all humans, helps better understand the physiology of the human body. Information on the gut microbiome of a diseased person can help diagnose and treat disease. The pancreatobiliary system releases functional antimicrobial substances, such as bile acids and antimicrobial peptides, which affect the gut microbiota directly. In re...
Source: Korean J Gastroenter... - May 24, 2020 Category: Gastroenterology Authors: Ryu KH Tags: Korean J Gastroenterol Source Type: research

[Obesity and Pancreatobiliary Disease].
This study reviewed the literature on obesity and pancreatobiliary disease in terms of epidemiology and mechanism. PMID: 32448855 [PubMed - in process] (Source: Korean J Gastroenter...)
Source: Korean J Gastroenter... - May 24, 2020 Category: Gastroenterology Authors: Lee H, Koh DH Tags: Korean J Gastroenterol Source Type: research

[Novel Insights of Primary Sclerosing Cholangitis and Primary Biliary Cholangitis].
Abstract Primary sclerosing cholangitis (PSC) and primary biliary cholangitis (PBC) are immune-mediated chronic liver diseases. PSC is a rare disorder characterized by multi-focal bile duct strictures and progressive liver diseases that ultimately results in the need for liver transplantation in most patients. Imaging studies, such as MRCP, have an essential role in the diagnosis of most cases of PSC. PSC is usually accompanied by inflammatory bowel disease, and there is a high risk of cholangiocarcinoma and colorectal cancer in PSC. No medical therapies have been proven to delay the progression of PSC. Endoscopic...
Source: Korean J Gastroenter... - May 24, 2020 Category: Gastroenterology Authors: Ahn DW Tags: Korean J Gastroenterol Source Type: research

[Recent Updates of Immunoglobulin G4-related Pancreatobiliary Disease].
Abstract Type 1 autoimmune pancreatitis and IgG4-related sclerosing cholangitis (IgG4-SC) are the pancreatobiliary manifestations of IgG4-related disease. IgG4-related disease is a newly named fibroinflammatory condition that is characterized by tumefactive lesions that contain dense lymphoplasmacytic infiltrates rich in IgG4-positive cells and often by elevated serum IgG4 concentrations. IgG4-related pancreatobiliary disease is often disguised as pancreatobiliary malignancies owing to its tumefactive nature and clinical presentations, such as obstructive jaundice. The differentiation of IgG4-SC from primary scler...
Source: Korean J Gastroenter... - May 24, 2020 Category: Gastroenterology Authors: Lee GC, Moon SH Tags: Korean J Gastroenterol Source Type: research