Innovations in Microsurgical Reconstruction in the Upper Extremity
Reconstruction of skin and soft tissue defects is essential for good outcomes in the hand and upper extremity after trauma, cancer resection, or other indications. At the apex of the reconstructive ladder is microsurgical reconstruction through free-tissue transfer, which closes defects that cannot be achieved through less-arduous techniques, such as pedicled flaps, local tissue rearrangement, or skin grafts. (Source: Hand Clinics)
Source: Hand Clinics - March 13, 2024 Category: Orthopaedics Authors: Harvey Chim, Kevin C. Chung Tags: Preface Source Type: research

Catastrophic skin necrosis after total knee arthroplasty: a case report and review of the literature
CONCLUSION: A balance must be achieved between the ability to expose the knee through a prior incision and avoiding extensive undermining of the subcutaneous flaps in patients with previous knee surgery. It may be a better approach to ignore medial incisions and use the classic midline incision.PMID:38463118 | PMC:PMC10923309 | DOI:10.1097/MS9.0000000000001085 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Amir Human Hoveidaei Hamidreza Zafari Peyman Mirghaderi Ehsan Ghadimi Sm Javad Mortazavi Source Type: research

Survey of European Blood and Marrow Transplant (EBMT) nurses to explore the current topical skin management of chronic cutaneous graft versus host disease in the real-world clinical environment
CONCLUSIONS: Topical treatment is the backbone of any treatment paradigm for chronic cutaneous graft versus host disease, however, there is no universally agreed algorithm. Improved skin care may lead to a reduction in the amount of systemic therapy required, thus increasing patients' quality of life. There is little standardisation in the topical management of chronic cutaneous graft versus host disease, despite skin being the most cited organ affected by chronic graft versus host disease, this should be addressed.PMID:38467081 | DOI:10.1016/j.ejon.2024.102547 (Source: European Journal of Oncology Nursing)
Source: European Journal of Oncology Nursing - March 11, 2024 Category: Nursing Authors: John Murray Sarah Liptrott Marta Canesi Jarl Mooyaart Annika Kisch Brian Piepenbroek Jacqui Stringer Source Type: research

Catastrophic skin necrosis after total knee arthroplasty: a case report and review of the literature
CONCLUSION: A balance must be achieved between the ability to expose the knee through a prior incision and avoiding extensive undermining of the subcutaneous flaps in patients with previous knee surgery. It may be a better approach to ignore medial incisions and use the classic midline incision.PMID:38463118 | PMC:PMC10923309 | DOI:10.1097/MS9.0000000000001085 (Source: Annals of Medicine)
Source: Annals of Medicine - March 11, 2024 Category: Internal Medicine Authors: Amir Human Hoveidaei Hamidreza Zafari Peyman Mirghaderi Ehsan Ghadimi Sm Javad Mortazavi Source Type: research

Survey of European Blood and Marrow Transplant (EBMT) nurses to explore the current topical skin management of chronic cutaneous graft versus host disease in the real-world clinical environment
CONCLUSIONS: Topical treatment is the backbone of any treatment paradigm for chronic cutaneous graft versus host disease, however, there is no universally agreed algorithm. Improved skin care may lead to a reduction in the amount of systemic therapy required, thus increasing patients' quality of life. There is little standardisation in the topical management of chronic cutaneous graft versus host disease, despite skin being the most cited organ affected by chronic graft versus host disease, this should be addressed.PMID:38467081 | DOI:10.1016/j.ejon.2024.102547 (Source: European Journal of Oncology Nursing)
Source: European Journal of Oncology Nursing - March 11, 2024 Category: Nursing Authors: John Murray Sarah Liptrott Marta Canesi Jarl Mooyaart Annika Kisch Brian Piepenbroek Jacqui Stringer Source Type: research

Multifunctional Hydrogel Enhances Inflammatory Control, Antimicrobial Activity, and Oxygenation to Promote Healing in Infectious Wounds
Biomacromolecules. 2024 Mar 8. doi: 10.1021/acs.biomac.3c01386. Online ahead of print.ABSTRACTChronic infected wounds often fail to heal through normal repair mechanisms, and the persistent response of reactive oxygen species (ROS) and inflammation is a major contributing factor to the difficulty in their healing. In this context, we developed an ROS-responsive injectable hydrogel. This hydrogel is composed of ε-polylysine grafted (EPL) with caffeic acid (CA) and hyaluronic acid (HA) grafted with phenylboronic acid (PBA). Before the gelation process, a mixture CaO2@Cur-PDA (CCP) consisting of calcium peroxide (CaO2) coate...
Source: Biomacromolecules - March 8, 2024 Category: Biochemistry Authors: Yunfeng Tang Renliang Zhao Min Yi Zilu Ge Dong Wang Guanglin Wang Xiangtian Deng Source Type: research

Multifunctional Hydrogel Enhances Inflammatory Control, Antimicrobial Activity, and Oxygenation to Promote Healing in Infectious Wounds
Biomacromolecules. 2024 Mar 8. doi: 10.1021/acs.biomac.3c01386. Online ahead of print.ABSTRACTChronic infected wounds often fail to heal through normal repair mechanisms, and the persistent response of reactive oxygen species (ROS) and inflammation is a major contributing factor to the difficulty in their healing. In this context, we developed an ROS-responsive injectable hydrogel. This hydrogel is composed of ε-polylysine grafted (EPL) with caffeic acid (CA) and hyaluronic acid (HA) grafted with phenylboronic acid (PBA). Before the gelation process, a mixture CaO2@Cur-PDA (CCP) consisting of calcium peroxide (CaO2) coate...
Source: Cancer Control - March 8, 2024 Category: Cancer & Oncology Authors: Yunfeng Tang Renliang Zhao Min Yi Zilu Ge Dong Wang Guanglin Wang Xiangtian Deng Source Type: research