EPAS1 and VEGFA gene variants are related to the symptoms of acute mountain sickness in Chinese Han population: a cross-sectional study
AbstractBackgroundMore people ascend to high altitude (HA) for various activities, and some individuals are susceptible to HA illness after rapidly ascending from plains. Acute mountain sickness (AMS) is a general complaint that affects activities of daily living at HA. Although genomic association analyses suggest that single nucleotide polymorphisms (SNPs) are involved in the genesis of AMS, no major gene variants associated with AMS-related symptoms have been identified.MethodsIn this cross-sectional study, 604 young, healthy Chinese Han men were recruited in June and July of 2012 in Chengdu, and rapidly taken to above ...
Source: Military Medical Research - July 27, 2020 Category: International Medicine & Public Health Source Type: research

Meta-analysis of the success rate of heartbeat recovery in patients with prehospital cardiac arrest in the past 40  years in China
Conclusions(1) The HRR is time-sensitive, and early rescue can improve it. (2) CPR performed within the platinum ten minutes must be executed by the public, and other forces are auxiliary. (3) The concept of peri-cardiac arrest period (PCAP)  should be established and improved to guide CPR. (Source: Military Medical Research)
Source: Military Medical Research - July 7, 2020 Category: International Medicine & Public Health Source Type: research

Validation of the age-adjusted shock index for pediatric casualties in Iraq and Afghanistan
ConclusionsWithin the combat setting, the age-adjusted pediatric shock index had moderate sensitivity and relatively poor specificity for predicting massive transfusion and death. Better scoring systems are needed to predict resource needs prior to arrival, that perhaps include other physiologic metrics. We were unable to validate the previously published findings within the combat trauma population. (Source: Military Medical Research)
Source: Military Medical Research - July 2, 2020 Category: International Medicine & Public Health Source Type: research

Real-time ultrasound-guided external intracerebral hemorrhage drain placement
We report a new minimally invasive technique utilizing interventional ultrasound for precise external intracerebral hemorrhage drain (EICHD) placement in pigs. (Source: Military Medical Research)
Source: Military Medical Research - July 2, 2020 Category: International Medicine & Public Health Source Type: research

Neuroregeneration and plasticity: a review of the physiological mechanisms for achieving functional recovery postinjury
AbstractNeuronal networks, especially those in the central nervous system (CNS), evolved to support extensive functional capabilities while ensuring stability. Several physiological “brakes” that maintain the stability of the neuronal networks in a healthy state quickly become a hinderance postinjury. These “brakes” include inhibition from the extracellular environment, intrinsic factors of neurons and the control of neuronal plasticity. There are distinct differences b etween the neuronal networks in the peripheral nervous system (PNS) and the CNS. Underpinning these differences is the trade-off be...
Source: Military Medical Research - June 11, 2020 Category: International Medicine & Public Health Source Type: research

Incidence, casualties and risk characteristics of civilian explosion blast injury in China: 2000 —2017 data from the state Administration of Work Safety
ConclusionsThe incidence and civilian casualties due to explosions remain unacceptabe in developing China. Measures that mitigate the risk factors are of urgently required. (Source: Military Medical Research)
Source: Military Medical Research - June 11, 2020 Category: International Medicine & Public Health Source Type: research

Incidence and risk factors associated with injuries during static line parachute training in Royal Thai Army
ConclusionsTo prevent military static line parachute injuries, the following factors should be taken into consideration: type of aircraft, aircraft exit, time of the day, equipment, motion sickness and wind speed.Trial registrationThe project was certified by the Research Ethics Committee, Faculty of Medicine, Chulalongkorn University (IRB No. 697/60). (Source: Military Medical Research)
Source: Military Medical Research - June 7, 2020 Category: International Medicine & Public Health Source Type: research

Pattern of liver injury in adult patients with COVID-19: a retrospective analysis of 105 patients
AbstractBackgroundRecent studies reported that patients with coronavirus disease-2019 (COVID-19) might have liver injury. However, few data on the combined analysis and change patterns of alanine aminotransferase (ALT), aspartate aminotransferase (AST) and total bilirubin (TBil) have been shown.MethodsThis is a single-center retrospective study. A total of 105 adult patients hospitalized for confirmed COVID-19 in Beijing Ditan Hospital between January 12, and March 17, 2020 were included, and divided into mild group (n = 79) and severe group(n = 26). We compared liver functional test results bet...
Source: Military Medical Research - June 7, 2020 Category: International Medicine & Public Health Source Type: research

Models to predict injury, physical fitness failure and attrition in recruit training: a retrospective cohort study
ConclusionAttrition rate was similar between 28-day and 80-day courses. In comparison to the 80-day full course, the 28-day course had a lower rate of injury but a higher number of injuries per person-year and of fitness test failure. These findings suggest fitness level at the commencement of training is a critically important factor to consider when designing the course curriculum, particularly short courses. (Source: Military Medical Research)
Source: Military Medical Research - June 3, 2020 Category: International Medicine & Public Health Source Type: research

Effects of Mycobacterium vaccae vaccine in a mouse model of tuberculosis: protective action and differentially expressed genes
ConclusionsM. vaccae vaccine provided good protection in mice againstM. tuberculosis infection, via a highly complex set of molecular changes. Our findings may provide clue to guide development of more effective vaccine against tuberculosis. (Source: Military Medical Research)
Source: Military Medical Research - June 3, 2020 Category: International Medicine & Public Health Source Type: research

Practice parameters for the use of actigraphy in the military operational context: the Walter Reed Army Institute of Research Operational Research Kit-Actigraphy (WORK-A)
ConclusionsDefault actigraphy methods are not the most accurate methods for characterizing soldier sleep, but reliable methods for characterizing operational sleep patterns is a necessary first step in developing strategies to improve soldier readiness. The WORK-A addresses this knowledge gap by providing practice parameters and a robust variety of measures with which to profile sleep behavior in service members. (Source: Military Medical Research)
Source: Military Medical Research - May 31, 2020 Category: International Medicine & Public Health Source Type: research

Perceived infection transmission routes, infection control practices, psychosocial changes, and management of COVID-19 infected healthcare workers in a tertiary acute care hospital in Wuhan: a cross-sectional survey
ConclusionThe main perceived mode of transmission was not maintaining protection when working at a close distance and having intimate contact with infected cases. Positive psychological intervention is necessary. (Source: Military Medical Research)
Source: Military Medical Research - May 11, 2020 Category: International Medicine & Public Health Source Type: research

Sequential intraventricular injection of tigecycline and polymyxin B in the treatment of intracranial Acinetobacter baumannii infection after trauma: a case report and review of the literature
ConclusionsThe polymyxin B IV  + IVT pathway is an ideal treatment strategy for XDRA. baumannii. The tigecycline IVT pathway is also a safe treatment option. (Source: Military Medical Research)
Source: Military Medical Research - May 10, 2020 Category: International Medicine & Public Health Source Type: research

Role of adjunctive treatment strategies in COVID-19 and a review of international and national clinical guidelines
AbstractThe coronavirus disease (COVID-19) pandemic has led to a global struggle to cope with the sheer numbers of infected persons, many of whom require intensive care support or eventually succumb to the illness. The outbreak is managed by a combination of disease containment via public health measures and supportive care for those who are affected. To date, there is no specific anti-COVID-19 treatment. However, the urgency to identify treatments that could turn the tide has led to the emergence of several investigational drugs as potential candidates to improve outcome, especially in the severe to critically ill. While ...
Source: Military Medical Research - May 5, 2020 Category: International Medicine & Public Health Source Type: research

Ex vivo limb perfusion for traumatic amputation in military medicine
AbstractBackgroundLimb loss has a drastic impact on a patient ’s life. Severe trauma to the extremities is common in current military conflicts. Among other aspects, “life before limb” damage control surgery hinders immediate replantation within the short post-traumatic timeframe, which is limited in part by the ischemic time for successful replantation. Ex vivo limb perfusion is currently being researched in animal models and shows promising results for its application in human limb replantation and allotransplantation.Presentation of the hypothesisThe current lack of replantation possibilities in milita...
Source: Military Medical Research - April 26, 2020 Category: International Medicine & Public Health Source Type: research

Chitosan hydrogel encapsulated with LL-37 peptide promotes deep tissue injury healing in a mouse model
ConclusionChitosan hydrogel encapsulated with LL-37 is biocompatible and could promote the healing of pressure ulcers. (Source: Military Medical Research)
Source: Military Medical Research - April 22, 2020 Category: International Medicine & Public Health Source Type: research

Chinese expert consensus on diagnosis and treatment of coagulation dysfunction in COVID-19
AbstractSince December 2019, a novel type of coronavirus disease (COVID-19) in Wuhan led to an outbreak throughout China and the rest of the world. To date, there have been more than 1,260,000 COVID-19 patients, with a mortality rate of approximately 5.44%. Studies have shown that coagulation dysfunction is a major cause of death in patients with severe COVID-19. Therefore, the People ’s Liberation Army Professional Committee of Critical Care Medicine and Chinese Society on Thrombosis and Hemostasis grouped experts from the frontline of the Wuhan epidemic to come together and develop an expert consensus on diagn...
Source: Military Medical Research - April 20, 2020 Category: International Medicine & Public Health Source Type: research

Fit to fight – from military hygiene to wellbeing in the British Army
AbstractThis paper reviews the historical evolution of the language and organization surrounding the health of personnel in the British Army from ‘hygiene’ through  to ‘wellbeing’. It starts by considering the health of the army in the mid-nineteenth century and the emergence of military hygiene as a professional subject. It continues by looking at advances in military hygiene in the two world wars. Hygiene was replaced by the term ‘ health’ in the 1950s as the collective noun used by professionals working in this field. This unity split when the professions of occupational medicine...
Source: Military Medical Research - April 7, 2020 Category: International Medicine & Public Health Source Type: research

Updating the diagnostic criteria of COVID-19 “suspected case” and “confirmed case” is necessary
AbstractOn 6 February 2020, our team had published a rapid advice guideline for diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infection, and this guideline provided our experience and make well reference for fighting against this pandemic worldwide. However, the coronavirus disease 2019 (COVID-19) is a new disease, our awareness and knowledge are gradually increasing based on the ongoing research findings and clinical practice experience; hence, the strategies of diagnosis and treatment are also continually updated. In this letter, we answered one comment on our guideline and provided the newest diagnostic ...
Source: Military Medical Research - April 4, 2020 Category: International Medicine & Public Health Source Type: research

Primary stratification and identification of suspected Corona virus disease 2019 (COVID-19) from clinical perspective by a simple scoring proposal
AbstractIn this Commentary, we would like to comment on the article titled “A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)” as a featured article inMilitary Medical Research. In the guideline, except for “confirmed cases”, “suspected cases”, “close contact” and “suspicious exposure” were defined by clinical perspective based on epidemiological risk, clinical symptoms and auxiliary examination. Combined with our experience, we introduced a simple scoring proposal additionally base...
Source: Military Medical Research - April 4, 2020 Category: International Medicine & Public Health Source Type: research

Expert consensus on the diagnosis and treatment of thrombocytopenia in adult critical care patients in China
AbstractThrombocytopenia is a common complication of critical care patients. The rates of bleeding events and mortality are also significantly increased in critical care patients with thrombocytopenia. Therefore, the Critical Care Medicine Committee of Chinese People ’s Liberation Army (PLA) worked with Chinese Society of Laboratory Medicine, Chinese Medical Association to develop this consensus to provide guidance for clinical practice. The consensus includes five sections and 27 items: the definition of thrombocytopenia, etiology and pathophysiology, diagnos is and differential diagnosis, treatment and prevention. ...
Source: Military Medical Research - April 3, 2020 Category: International Medicine & Public Health Source Type: research

Predictors of contrast-induced acute kidney injury in patients with coronary artery disease receiving contrast agents twice within 30  days
ConclusionsDiuretic and IABP usage are independent predictors of CI-AKI following exposure to a first contrast agent. The major predictors of CI-AKI after exposure to a second agent are time since the first contrast exposure, ACEI/ARB usage, and IABP usage. More importantly, a three-day interval between the two agents is associated with a higher incidence of CI-AKI following the second administration. (Source: Military Medical Research)
Source: Military Medical Research - March 26, 2020 Category: International Medicine & Public Health Source Type: research

Hemostatic agents for prehospital hemorrhage control: a narrative review
AbstractHemorrhage is the leading cause of preventable death in combat trauma and the secondary cause of death in civilian trauma. A significant number of deaths due to hemorrhage occur before and in the first hour after hospital arrival. A literature search was performed through PubMed, Scopus, and Institute of Scientific Information databases for English language articles using terms relating to hemostatic agents, prehospital, battlefield or combat dressings, and prehospital hemostatic resuscitation, followed by cross-reference searching. Abstracts were screened to determine relevance and whether appropriate further revi...
Source: Military Medical Research - March 25, 2020 Category: International Medicine & Public Health Source Type: research

Correction to: Does the preoperative platelet-tolymphocyte ratio and neutrophil-tolymphocyte ratio predict morbidity after gastrectomy for gastric cancer?
In the original publication of this article [1] there are two garbled codes in the second sentence, the fourth paragraph of the Background section. The correct sentence should be: Tumor growth leads to the increased production of inflammatory cytokines and growth factors (mainly IL-1, IL-3, IL-6, IL-11, IL-23, and TNF-), and this perpetual process ensures immortality. These promoting factors are also important for angiogenesis and hematopoiesis, which explains the increase in blood cell types in cancerous diseases. The original publication has been corrected. (Source: Military Medical Research)
Source: Military Medical Research - March 23, 2020 Category: International Medicine & Public Health Source Type: research

The origin, transmission and clinical therapies on coronavirus disease 2019 (COVID-19) outbreak – an update on the status
AbstractAn acute respiratory disease, caused by a novel coronavirus (SARS-CoV-2, previously known as 2019-nCoV), the coronavirus disease 2019 (COVID-19) has spread throughout China and received worldwide attention. On 30 January 2020, World Health Organization (WHO) officially declared the COVID-19 epidemic as a public health emergency of international concern. The emergence of SARS-CoV-2, since the severe acute respiratory syndrome coronavirus (SARS-CoV) in 2002 and Middle East respiratory syndrome coronavirus (MERS-CoV) in 2012, marked the third introduction of a highly pathogenic and large-scale epidemic coronavirus int...
Source: Military Medical Research - March 13, 2020 Category: International Medicine & Public Health Source Type: research

Sleep disturbances and predictors of nondeployability among active-duty Army soldiers: an odds ratio analysis of medical healthcare data from fiscal year 2018
ConclusionNearly half of soldiers had a sleep disorder or sleep-related medical diagnosis in 2018, but their sleep problems are largely not profiled as limitations to medical readiness. Musculoskeletal issues and physical injury predict nondeployability, and nondeployability is more likely to occur in soldiers who have sleep e-Profiles in addition to these issues. Addressing sleep problems may prevent accidents and injuries that could render a soldier nondeployable. (Source: Military Medical Research)
Source: Military Medical Research - March 10, 2020 Category: International Medicine & Public Health Source Type: research

Methodological quality (risk of bias) assessment tools for primary and secondary medical studies: what are they and which is better?
AbstractMethodological quality (risk of bias) assessment is an important step before study initiation usage. Therefore, accurately judging study type is the first priority, and the choosing proper tool is also important. In this review, we introduced methodological quality assessment tools for randomized controlled trial (including individual and cluster), animal study, non-randomized interventional studies (including follow-up study, controlled before-and-after study, before-after/ pre-post study, uncontrolled longitudinal study, interrupted time series study), cohort study, case-control study, cross-sectional study (incl...
Source: Military Medical Research - February 29, 2020 Category: International Medicine & Public Health Source Type: research

Does the preoperative platelet-to-lymphocyte ratio and neutrophil-to-lymphocyte ratio predict morbidity after gastrectomy for gastric cancer?
ConclusionBased on the results of the study, the PLR and NLR could be used as independent predictive factors for mortality and morbidity in patients with gastric cancer. (Source: Military Medical Research)
Source: Military Medical Research - February 29, 2020 Category: International Medicine & Public Health Source Type: research

Beyond the burn: Studies on the physiological effects of flamethrowers during World War II
This article examines how the initial absence of scientific data on the physiologic effects of flamethrowers led to an inaccurate understanding of their let hality, and bizarre claims that one of history’s most horrific instruments of war was considered one of the more “humane” weapons on the battlefield. (Source: Military Medical Research)
Source: Military Medical Research - February 27, 2020 Category: International Medicine & Public Health Source Type: research

Smoking prevalence in the area of responsibility of the German Ministry of Defense — results of the employee survey in the context of occupational health management
This study analyzes current data in a large sample from this population.MethodsBased on an employee survey as part of the Occupational Health Management System, data on smoking behavior from 13,326 participants were analyzed in relation to age, gender, professional status, education level and membership in military operational units versus other agencies.ResultsSmoking behavior varied significantly (P   older), gender, professional status, military agency membership status, and education level (the lower the education level, the higher the smoking rates). With the exception of the downward trend in smoking behavior ...
Source: Military Medical Research - February 21, 2020 Category: International Medicine & Public Health Source Type: research

Characteristics of fever and response to antipyretic therapy in military personnel with adenovirus-positive community-acquired pneumonia
AbstractBackgroundIn 2014, an outbreak of adenoviral pneumonia occurred in the Korean military training center. However, there are limited data on the characteristics of the fever and its response to antipyretic therapy in immunocompetent adults with adenovirus-positive community-acquired pneumonia (CAP).MethodsThe medical records of the patients who were admitted to the Armed Forces Chuncheon Hospital for the treatment of CAP between January 2014 and December 2016 were retrospectively analyzed. The patients were divided into three groups, namely, the adenovirus-positive (Adv) group, the adenovirus-negative (Non-Adv) group...
Source: Military Medical Research - February 21, 2020 Category: International Medicine & Public Health Source Type: research

A rapid advice guideline for the diagnosis and treatment of 2019 novel coronavirus (2019-nCoV) infected pneumonia (standard version)
AbstractIn December 2019, a new type viral pneumonia cases occurred in Wuhan, Hubei Province; and then named “2019 novel coronavirus (2019-nCoV)” by the World Health Organization (WHO) on 12 January 2020. For it is a never been experienced respiratory disease before and with infection ability widely and quickly, it attracted the world’s attention but without treatment and control manual. For the requ est from frontline clinicians and public health professionals of 2019-nCoV infected pneumonia management, an evidence-based guideline urgently needs to be developed. Therefore, we drafted this guideline accor...
Source: Military Medical Research - February 6, 2020 Category: International Medicine & Public Health Source Type: research

Cross-sectional study of the educational background and trauma knowledge of trainees in the “China trauma care training” program
AbstractBackgroundSince the trauma knowledge of trauma providers correlates with the outcomes of injured patients, this study aims to assess the socio-demographic characteristics and levels of trauma knowledge of trainees in the China trauma care training (CTCT) program in addition to their post-course test results to provide support for the development of trauma care training programs and trauma systems in China.MethodsA cross-sectional study was conducted by collecting demographic information, hospital-related information and trauma knowledge of the trainees from 19 regions in China. All participants were assessed by que...
Source: Military Medical Research - January 21, 2020 Category: International Medicine & Public Health Source Type: research

Preliminary evaluation of the VIsion PERformance (VIPER) simulator
This study evaluated the VIsion PERformance (VIPER) simulator ’s ability to assess the functional visual performance in warfighters conducting civilian and military tasks.MethodsThirty service members, aged 25 –35 years old with a best corrected distance visual acuity (VA) better than or equal to 20/20 or logarithm of the minimum angle of resolution (logMAR) 0.00, were randomized to locate and identify road signs and mock improvised explosive devices (IEDs) under either daytime conditions or with infr ared imagery, with (cc) and without (sc) wearing their habitual correction. Participants also underwent ...
Source: Military Medical Research - January 16, 2020 Category: International Medicine & Public Health Source Type: research

Expert consensus on the diagnosis and treatment of heat stroke in China
AbstractHeat stroke (HS) is a fatal disease caused by thermal damage in the body, and it has a very high mortality rate. In 2015, the People ’s Liberation Army Professional Committee of Critical Care Medicine published the first expert consensus on HS in China,Expert consensus on standardized diagnosis and treatment for heat stroke. With an increased understanding of HS and new issues that emerged during the HS treatment in China in recent years, the 2015 consensus no longer meet the requirements for HS prevention and treatment. It is necessary to update the consensus to include the latest research evidence and estab...
Source: Military Medical Research - January 13, 2020 Category: International Medicine & Public Health Source Type: research

An effective snakebite first aid training method for medics in the Chinese troops: a RCT
This study was a prospective single-blind randomized controlled trial conducted in a military medical university of China from May to June 2017. A questionnaire-based survey was performed to collect the participants ’ socio-demographic profiles before the baseline measurement. During the baseline measurement, participants were requested to provide corresponding first aid that was responsive to the simulative situation portrayed by the SPs (standardized patients) and the evaluators then scored their performanc es according to a checklist for snakebite first aid scoring table. After the baseline measurement, they were ...
Source: Military Medical Research - December 13, 2019 Category: International Medicine & Public Health Source Type: research

Sex-based differences in the prevalence of acute mountain sickness: a meta-analysis
ConclusionsAccording to this study, the statistically significant finding emerging from this study was that women have a higher prevalence of AMS. However, the authors could not exclude studies where patients were on acetazolamide. Our analysis provided a direction for future studies of the relationship of sex and the risk of AMS, such as the pathological mechanism and prevention research. (Source: Military Medical Research)
Source: Military Medical Research - December 9, 2019 Category: International Medicine & Public Health Source Type: research

A randomized trial comparing the Tennant Biomodulator to transcutaneous electrical nerve stimulation and traditional Chinese acupuncture for the treatment of chronic pain in military service members
AbstractBackgroundThe present investigation tested the efficacy of the Tennant Biomodulator, a novel pain management intervention that uses biofeedback-modulated electrical stimulation, to reduce chronic pain and its psychosocial sequelae in a sample of current and former military service members. The Tennant Biomodulator used on its most basic setting was compared to two commonly used, non-pharmacological  pain treatments—traditional Chinese acupuncture and transcutaneous electrical nerve stimulation (TENS)—in a comparative efficacy, randomized, open-label trial.MethodsParticipants included 100 active dut...
Source: Military Medical Research - December 2, 2019 Category: International Medicine & Public Health Source Type: research

Correlation between exercise, personal income level and health-related quality of life in patients with newly diagnosed stable angina
AbstractBackgroundStable angina is one of the most common clinical types of coronary artery disease (CAD) and associated with poor health-related quality of life (HRQL). However, few studies have evaluated the risk factors associated with HRQL in patients with newly diagnosed stable angina.MethodsA cross-sectional survey was conducted with 342 consecutive outpatients with newly diagnosed stable angina from October 2017 to January 2018 at the Second Affiliated Hospital of Army Medical University, Chongqing, China. Eight dimensions of HRQL were evaluated via the 36-item Short-Form Health Survey, including physical functionin...
Source: Military Medical Research - November 25, 2019 Category: International Medicine & Public Health Source Type: research

Surgical restoration of drop-hand syndrome with tendon transfer in patients injured in the Syrian civil war
ConclusionsIn radial nerve injuries, successful results can be achieved with tendon transfer. All patients regained thumb abduction of up to approximately 60 °. All the patients were able to bend the wrist, grip, and extend the fingers while in wrist flexion, neutral wrist and wrist extension positions. Although the reason for the radial injury varied, the postoperative outcomes were good for all patients, and the rehabilitation period progressed succes sfully in patients who underwent tendon transfer repair within 90 days of injury. (Source: Military Medical Research)
Source: Military Medical Research - November 19, 2019 Category: International Medicine & Public Health Source Type: research

Periodontal disease and risk of benign prostate hyperplasia: a cross-sectional study
ConclusionPeriodontal disease is significantly and positively associated with an increased risk of benign prostatic hyperplasia. Further validation studies should be performed to explore the relationship between periodontal treatment and benign prostate hyperplasia. (Source: Military Medical Research)
Source: Military Medical Research - November 13, 2019 Category: International Medicine & Public Health Source Type: research

Discovering myeloid cell heterogeneity in the lung by means of next generation sequencing
AbstractThe lung plays a vital role in maintaining homeostasis, as it is responsible for the exchange of oxygen and carbon dioxide. Pulmonary homeostasis is maintained by a network of tissue-resident cells, including epithelial cells, endothelial cells and leukocytes. Myeloid cells of the innate immune system and epithelial cells form a critical barrier in the lung. Recently developed unbiased next generation sequencing (NGS) has revealed cell heterogeneity in the lung with respect to physiology and pathology and has reshaped our knowledge. New phenotypes and distinct gene signatures have been identified, and these new fin...
Source: Military Medical Research - October 25, 2019 Category: International Medicine & Public Health Source Type: research

Boron neutron capture therapy: moving towards targeted therapy for locally recurrent head and neck squamous cell carcinoma
AbstractLocally recurrent head and neck squamous cell carcinoma (HNSCC) is often unresectable, and a repeat course of radiotherapy is associated with incremental toxicities. Boron neutron capture therapy (BNCT) is a novel targeted radiotherapy modality that can achieve a high dose gradient between cancerous and adjacent normal tissues. However, the relationships among the dose resulting from BNCT, tumor response to BNCT, and survival are not completely understood. Recently, a study published inRadiotherapy and Oncology investigated the efficacy of BNCT in the treatment of patients with locally recurrent HNSCC and the facto...
Source: Military Medical Research - October 25, 2019 Category: International Medicine & Public Health Source Type: research

Progression of intervention-focused research for Gulf War illness
AbstractThe Persian Gulf War of 1990 to 1991 involved the deployment of nearly 700,000 American troops to the Middle East. Deployment-related exposures to toxic substances such as pesticides, nerve agents, pyridostigmine bromide (PB), smoke from burning oil wells, and petrochemicals may have contributed to medical illness in as many as 250,000 of those American troops. The cluster of chronic symptoms, now referred to as Gulf War Illness (GWI), has been studied by many researchers over the past two decades. Although over $500 million has been spent on GWI research, to date, no cures or condition-specific treatments have bee...
Source: Military Medical Research - October 18, 2019 Category: International Medicine & Public Health Source Type: research

A longitudinal analysis of the U.S. Air Force reserve officers ’ training corps physical fitness assessment
ConclusionThe results indicated that only the sit-up component showed differences between class ranks. These findings suggest that the Air Force PFA may not be sensitive enough to detect changes in physical fitness or distinguish between class ranks regarding physical performance, even after years of training. This limitation may be in part due to the limited duration of training incorporated by the ROTC program (2  h per week), which provided a maintenance effect rather than improvement in physical performance. We recommend that more attention be directed to the efficacy of physical training, the sensitivity of mea...
Source: Military Medical Research - September 23, 2019 Category: International Medicine & Public Health Source Type: research

High-dependency units play a key role in the treatment of a Chinese military patient who developed liver failure while abroad
AbstractHigh-dependency units (HDUs) provide high-level care to patients who suffer from single organ failure, with the exception of respiratory failure requiring mechanical ventilation; HDUs serve as an intermediary between general wards and Intensive Care Units. Due to military and civilian needs, our hospital has established a unique HDU for patients with liver disease in China. A Chinese military officer in the United Nations Peacekeeping Forces in South Sudan was transferred to our HDU for liver failure treatment in 2018. The patient ’s disease status, nutrition, sleep habits, and psychological behaviour were mo...
Source: Military Medical Research - September 16, 2019 Category: International Medicine & Public Health Source Type: research

Equine-assisted interventions for veterans with service-related health conditions: a systematic mapping review
ConclusionsScientific development of equine-assisted interventions targeting psychosocial outcomes among veterans is warranted to establish their efficacy. Targeted outcomes should be expanded, including outcomes more closely aligned with the nature of polytraumatic injuries. Future research must also emphasize the theoretical development of equine-assisted interventions for veterans and thoroughly describe the participants, components of the intervention, factors contributing to attrition, and optimal dose-response relationships. (Source: Military Medical Research)
Source: Military Medical Research - August 29, 2019 Category: International Medicine & Public Health Source Type: research

Femoroacetabular impingement is more common in military veterans with end-stage hip osteoarthritis than civilian patients: a retrospective case control study
ConclusionThese results suggest that FAI is perhaps a more common mechanism in the progression of OA in a veteran population than in a civilian population, as pincer and mixed-type deformities were significantly more common among veterans than civilians. The forces borne by the hip during military training exceed normal physiologic conditions. In addition, the time between symptom onset and surgical correction may be 10 –12 months longer for active military personnel than for civilians. The combination of increased physical demands and a protracted time to treatment highlights the need for better recognition o...
Source: Military Medical Research - August 23, 2019 Category: International Medicine & Public Health Source Type: research

Comparison of dietary intakes of Canadian Armed Forces personnel consuming field rations in acute hot, cold, and temperate conditions with standardized infantry activities
ConclusionThese results should be considered when planning the provision of field rations for CAF personnel expected to be engaged in strenuous physical activities with prolonged exposure to temperature extremes. (Source: Military Medical Research)
Source: Military Medical Research - August 16, 2019 Category: International Medicine & Public Health Source Type: research

Publisher Correction to: Military Medical Research, volume 6
An error occurred during the publication of a number of articles inMilitary Medical Research. (Source: Military Medical Research)
Source: Military Medical Research - August 7, 2019 Category: International Medicine & Public Health Source Type: research