Systematic Review on the Relationship between Toxoplasmosis and Mental Disorders
CONCLUSIONS: Due to the limits of the study, no conclusions can be drawn in childhood and adolescence. However, the results of this systematic review show a possible association of schizophrenia, bipolar disorder and compulsive disorder with T. gondii infection in adults. There is a need to improve control, integrated surveillance and extend prevention measures to the entire population.PMID:38622004 | PMC:PMC11015818 | DOI:10.62641/aep.v52i2.1658 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Leticia E Bartolom é Del Pino Vicente Zan ón-Moreno Source Type: research

The impact of familial involvement on dropout in a culturally informed group therapy for people diagnosed with 'schizophrenia'
We examined whether familial involvement and other demographic variables predicted dropout among 101 patients enrolled in culturally informed group therapy for schizophrenia (CIGT-S), which incorporates collectivistic principles and spiritual coping into treatment. We reviewed records and conducted follow-up calls to identify reasons for dropout, and performed survival analyses to identify when dropout was likely.RESULTS: Familial involvement was linked to greater engagement with treatment and lower dropout, signifying a mechanism for improving treatment attendance in this group. Ethnic minorities and patients with higher ...
Source: Psychosis - April 15, 2024 Category: Psychiatry Authors: Jessica Maura Salman Shaheen Ahmad Amy Weisman de Mamani Source Type: research

Systematic Review on the Relationship between Toxoplasmosis and Mental Disorders
CONCLUSIONS: Due to the limits of the study, no conclusions can be drawn in childhood and adolescence. However, the results of this systematic review show a possible association of schizophrenia, bipolar disorder and compulsive disorder with T. gondii infection in adults. There is a need to improve control, integrated surveillance and extend prevention measures to the entire population.PMID:38622004 | PMC:PMC11015818 | DOI:10.62641/aep.v52i2.1658 (Source: Actas Espanolas de Psiquiatria)
Source: Actas Espanolas de Psiquiatria - April 15, 2024 Category: Psychiatry Authors: Leticia E Bartolom é Del Pino Vicente Zan ón-Moreno Source Type: research

The impact of familial involvement on dropout in a culturally informed group therapy for people diagnosed with 'schizophrenia'
We examined whether familial involvement and other demographic variables predicted dropout among 101 patients enrolled in culturally informed group therapy for schizophrenia (CIGT-S), which incorporates collectivistic principles and spiritual coping into treatment. We reviewed records and conducted follow-up calls to identify reasons for dropout, and performed survival analyses to identify when dropout was likely.RESULTS: Familial involvement was linked to greater engagement with treatment and lower dropout, signifying a mechanism for improving treatment attendance in this group. Ethnic minorities and patients with higher ...
Source: Psychosis - April 15, 2024 Category: Psychiatry Authors: Jessica Maura Salman Shaheen Ahmad Amy Weisman de Mamani Source Type: research

Risk of Cardiovascular Events in Schizophrenic Patients Treated with Paliperidone Palmitate Once-Monthly Injection (PP1M): A Population-Based Retrospective Cohort Study in Taiwan
ConclusionThis study reported the population-based incidence of cardiovascular events in schizophrenic patients initiating PP1M treatment. PP1M was not associated with increased risks of serious cardiovascular events but was potentially associated with lower risks of cardiovascular hospitalizations compared with oral SGAs. (Source: Clinical Drug Investigation)
Source: Clinical Drug Investigation - April 15, 2024 Category: Drugs & Pharmacology Source Type: research

Blood Cell Count Ratios at Baseline are Associated with Initial Clinical Response to Clozapine in Treatment-Resistant, Clozapine-Na ïve, Schizophrenia-Spectrum Disorder
Conclusion Our study emphasizes the potential clinical significance of baseline NLR and MLR levels as predictors of initial clozapine treatment response in patients with TRS. Future studies with larger sample sizes and longer follow-up periods should replicate our findings. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text (Source: Pharmacopsychiatry)
Source: Pharmacopsychiatry - April 15, 2024 Category: Psychiatry Authors: Llorca-Bof í, Vicent Bioque, Miquel Madero, Santiago Mallorqu í, Andrea Oliveira, Cristina Garriga, Marina Parellada, Eduard Garc ía-Rizo, Clemente Tags: Original Paper Source Type: research

Brain structural alterations associated with impulsiveness in male violent patients with schizophrenia
Violence in schizophrenia (SCZ) is a phenomenon associated with neurobiological factors. However, the neural mechanisms of violence in patients with SCZ are not yet sufficiently understood. Thus, this study ai... (Source: BMC Psychiatry)
Source: BMC Psychiatry - April 15, 2024 Category: Psychiatry Authors: Juntao Lu, Ningzhi Gou, Qiaoling Sun, Ying Huang, Huijuan Guo, Dian Han, Jiansong Zhou and Xiaoping Wang Tags: Research Source Type: research

Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia
CONCLUSION: We conclude that LT-102 ameliorates cognitive impairments in a phencyclidine-induced model of schizophrenia by enhancing synaptic function, which could make it a potential therapeutic candidate for CIAS.PMID:38615362 | PMC:PMC11016348 | DOI:10.1111/cns.14713 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Xueyu Qi Xueli Yu Long Wei Han Jiang Jiangwen Dong Hongxing Li Yingying Wei Liansheng Zhao Wei Deng Wanjun Guo Xun Hu Tao Li Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research

Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia
CONCLUSION: We conclude that LT-102 ameliorates cognitive impairments in a phencyclidine-induced model of schizophrenia by enhancing synaptic function, which could make it a potential therapeutic candidate for CIAS.PMID:38615362 | PMC:PMC11016348 | DOI:10.1111/cns.14713 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Xueyu Qi Xueli Yu Long Wei Han Jiang Jiangwen Dong Hongxing Li Yingying Wei Liansheng Zhao Wei Deng Wanjun Guo Xun Hu Tao Li Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research

Novel α-amino-3-hydroxy-5-methyl-4-isoxazole-propionic acid receptor (AMPAR) potentiator LT-102: A promising therapeutic agent for treating cognitive impairment associated with schizophrenia
CONCLUSION: We conclude that LT-102 ameliorates cognitive impairments in a phencyclidine-induced model of schizophrenia by enhancing synaptic function, which could make it a potential therapeutic candidate for CIAS.PMID:38615362 | PMC:PMC11016348 | DOI:10.1111/cns.14713 (Source: CNS Neuroscience and Therapeutics)
Source: CNS Neuroscience and Therapeutics - April 14, 2024 Category: Neuroscience Authors: Xueyu Qi Xueli Yu Long Wei Han Jiang Jiangwen Dong Hongxing Li Yingying Wei Liansheng Zhao Wei Deng Wanjun Guo Xun Hu Tao Li Source Type: research

Subregional thalamic functional connectivity abnormalities and cognitive impairments in first-episode schizophrenia
CONCLUSION: Our findings suggest FC abnormalities between thalamic subregions and cortical areas in FES patients. Increased FC correlated with cognitive deficits and negative symptoms, highlighting the importance of thalamo-cortical connectivity in the pathophysiology of schizophrenia.PMID:38615577 | DOI:10.1016/j.ajp.2024.104042 (Source: Asian Journal of Psychiatry)
Source: Asian Journal of Psychiatry - April 14, 2024 Category: Psychiatry Authors: Li-Na Wang Shuo Lin Lu Tian Han Wu Wen-Qing Jin Wen Wang Wei-Gang Pan Chun-Lin Yang Yan-Ping Ren Xin Ma Yi-Lang Tang Source Type: research

The burden for clinical services of persons with an intellectual disability or mental disorder convicted of criminal offences: A birth cohort study of 14,605 persons followed to age 64
CONCLUSION: Sub-groups of cohort members with ID or mental disorders were convicted of violent and non-violent crimes to age 64 suggesting the need for treatment of primary disorders and for antisocial/aggressive behavior. Many patients engaging in violence could be identified at first contact with clinical services.PMID:38613517 | DOI:10.1080/08039488.2024.2337192 (Source: Nordic Journal of Psychiatry)
Source: Nordic Journal of Psychiatry - April 13, 2024 Category: Psychiatry Authors: Sheilagh Hodgins Fredrik Sivertsson Amber Beckley Mimosa Luigi Christoffer Carlsson Source Type: research