The relationship between childhood trauma, psychotic symptoms, and cognitive schemas in patients with schizophrenia, their siblings, and healthy controls: results from the EU-GEI study
CONCLUSIONS: Our findings suggest that childhood abuse and neglect are more common in patients with schizophrenia than their siblings and healthy controls, and have different impacts on clinical domains which we searched. The relationship between CT and positive symptoms seems to be mediated by negative cognitive schemas about self in schizophrenia.PMID:38606591 | DOI:10.1017/S0033291724000540 (Source: Psychological Medicine)
Source: Psychological Medicine - April 12, 2024 Category: Psychiatry Authors: Alp Üçok Handan Noyan Sinan G ülöksüz Meram Can Saka K öksal Alptekin Cem Atba şoğlu El çin Akturan G ülşah Karadayı Zeynep Baran Tatar Berna Akdede Tolga Binbay Vesile Alt ınyazar Halis Ula ş Berna Yal ınçetin G üvem Gümüş-Akay Bur ç Source Type: research

Craniofacial anomalies in schizophrenia-relevant GFAP.HMOX1 < sup > 0-12m < /sup > mice
We examined craniofacial anatomy in male GFAP.HMOX10-12m mice and wild-type control mice at the early adulthood age of 6-8 months. We used computer vision techniques for the extraction and analysis of mouse head shape parameters from systematically acquired 2D digital images, and confirmed our results with landmark-based geometric morphometrics. We performed skull bone morphometry using digital calipers to take linear distance measurements between known landmarks. Relative to controls, adult male GFAP.HMOX10-12m mice manifested craniofacial dysmorphology including elongation of the nasal bones, alteration of head shape ani...
Source: Anatomical Record - April 12, 2024 Category: Anatomy Authors: Ayda Tavitian Joseph Somech Badrouyk Chamlian Adrienne Liberman Carmela Galindez Hyman M Schipper Source Type: research

The relationship between childhood trauma, psychotic symptoms, and cognitive schemas in patients with schizophrenia, their siblings, and healthy controls: results from the EU-GEI study
CONCLUSIONS: Our findings suggest that childhood abuse and neglect are more common in patients with schizophrenia than their siblings and healthy controls, and have different impacts on clinical domains which we searched. The relationship between CT and positive symptoms seems to be mediated by negative cognitive schemas about self in schizophrenia.PMID:38606591 | DOI:10.1017/S0033291724000540 (Source: Psychological Medicine)
Source: Psychological Medicine - April 12, 2024 Category: Psychiatry Authors: Alp Üçok Handan Noyan Sinan G ülöksüz Meram Can Saka K öksal Alptekin Cem Atba şoğlu El çin Akturan G ülşah Karadayı Zeynep Baran Tatar Berna Akdede Tolga Binbay Vesile Alt ınyazar Halis Ula ş Berna Yal ınçetin G üvem Gümüş-Akay Bur ç Source Type: research