The association between schizophrenia and increased COVID-19 mortality in a cohort of over 2 million people in Brazil
CONCLUSIONS: Patients diagnosed with schizophrenia have a greater likelihood of COVID-19- related death than those without mental health conditions. These findings underscore the significant effect of serious mental disorders on COVID-19 mortality.PMID:38635950 | DOI:10.47626/1516-4446-2024-3540 (Source: Revista Brasileira de Psiquiatria)
Source: Revista Brasileira de Psiquiatria - April 18, 2024 Category: Psychiatry Authors: Fabr ício Emanuel Soares de Oliveira Samuel Trezena Daniella Reis Barbosa Martelli Maria Christina L Oliveira Enrico A Colosimo Herc ílio Martelli Eduardo Ara újo Oliveira Source Type: research
Demographics and clinical characteristics of patients of prescribing psychologists, psychiatrists, and primary care physicians
Am Psychol. 2024 Apr 18. doi: 10.1037/amp0001352. Online ahead of print.ABSTRACTTo describe the characteristics of patients receiving psychotropic medication from prescribing psychologists, psychiatrists, and primary care physicians. This descriptive study was conducted using private insurance claims of patients from New Mexico and Louisiana receiving psychotropic medications (anticonvulsants, antidepressants, antipsychotics, hypotensive agents, anxiolytics/sedatives/hypnotics, and stimulants) from 2004 to 2021 (N = 307,478). Patient characteristics were captured during the 6 months prior to their first psychotropic medica...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Phillip M Hughes Joshua D Niznik Robert E McGrath Casey R Tak Robert B Christian Betsy L Sleath Kathleen C Thomas Source Type: research
The association between schizophrenia and increased COVID-19 mortality in a cohort of over 2 million people in Brazil
CONCLUSIONS: Patients diagnosed with schizophrenia have a greater likelihood of COVID-19- related death than those without mental health conditions. These findings underscore the significant effect of serious mental disorders on COVID-19 mortality.PMID:38635950 | DOI:10.47626/1516-4446-2024-3540 (Source: Revista Brasileira de Psiquiatria)
Source: Revista Brasileira de Psiquiatria - April 18, 2024 Category: Psychiatry Authors: Fabr ício Emanuel Soares de Oliveira Samuel Trezena Daniella Reis Barbosa Martelli Maria Christina L Oliveira Enrico A Colosimo Herc ílio Martelli Eduardo Ara újo Oliveira Source Type: research
Demographics and clinical characteristics of patients of prescribing psychologists, psychiatrists, and primary care physicians
Am Psychol. 2024 Apr 18. doi: 10.1037/amp0001352. Online ahead of print.ABSTRACTTo describe the characteristics of patients receiving psychotropic medication from prescribing psychologists, psychiatrists, and primary care physicians. This descriptive study was conducted using private insurance claims of patients from New Mexico and Louisiana receiving psychotropic medications (anticonvulsants, antidepressants, antipsychotics, hypotensive agents, anxiolytics/sedatives/hypnotics, and stimulants) from 2004 to 2021 (N = 307,478). Patient characteristics were captured during the 6 months prior to their first psychotropic medica...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Phillip M Hughes Joshua D Niznik Robert E McGrath Casey R Tak Robert B Christian Betsy L Sleath Kathleen C Thomas Source Type: research
Demographics and clinical characteristics of patients of prescribing psychologists, psychiatrists, and primary care physicians
Am Psychol. 2024 Apr 18. doi: 10.1037/amp0001352. Online ahead of print.ABSTRACTTo describe the characteristics of patients receiving psychotropic medication from prescribing psychologists, psychiatrists, and primary care physicians. This descriptive study was conducted using private insurance claims of patients from New Mexico and Louisiana receiving psychotropic medications (anticonvulsants, antidepressants, antipsychotics, hypotensive agents, anxiolytics/sedatives/hypnotics, and stimulants) from 2004 to 2021 (N = 307,478). Patient characteristics were captured during the 6 months prior to their first psychotropic medica...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Phillip M Hughes Joshua D Niznik Robert E McGrath Casey R Tak Robert B Christian Betsy L Sleath Kathleen C Thomas Source Type: research
Demographics and clinical characteristics of patients of prescribing psychologists, psychiatrists, and primary care physicians
Am Psychol. 2024 Apr 18. doi: 10.1037/amp0001352. Online ahead of print.ABSTRACTTo describe the characteristics of patients receiving psychotropic medication from prescribing psychologists, psychiatrists, and primary care physicians. This descriptive study was conducted using private insurance claims of patients from New Mexico and Louisiana receiving psychotropic medications (anticonvulsants, antidepressants, antipsychotics, hypotensive agents, anxiolytics/sedatives/hypnotics, and stimulants) from 2004 to 2021 (N = 307,478). Patient characteristics were captured during the 6 months prior to their first psychotropic medica...
Source: The American Psychologist - April 18, 2024 Category: Psychiatry & Psychology Authors: Phillip M Hughes Joshua D Niznik Robert E McGrath Casey R Tak Robert B Christian Betsy L Sleath Kathleen C Thomas Source Type: research
Rapid Metabolism Underlying Subtherapeutic Serum Levels of Atypical Antipsychotics Preceding Clozapine Treatment: A Retrospective Analysis of Real-World Data
ConclusionLCD and associated rapid metabolism of non-clozapine antipsychotics is frequent before starting clozapine treatment. For olanzapine and quetiapine, this is associated with significantly increased risk of having subtherapeutic concentrations. (Source: CNS Drugs)
Source: CNS Drugs - April 18, 2024 Category: Neurology Source Type: research
Dissecting the shared genetic landscape of anxiety, depression, and schizophrenia
Numerous studies highlight the genetic underpinnings of mental disorders comorbidity, particularly in anxiety, depression, and schizophrenia. However, their shared genetic loci are not well understood. Our stu... (Source: Journal of Translational Medicine)
Source: Journal of Translational Medicine - April 18, 2024 Category: Research Authors: Yiming Tao, Rui Zhao, Bin Yang, Jie Han and Yongsheng Li Tags: Research Source Type: research
Morphological heterogeneity of neurons in the human central amygdaloid nucleus
J Neurosci Res. 2024 Apr;102(4):e25319. doi: 10.1002/jnr.25319.ABSTRACTThe central amygdaloid nucleus (CeA) has an ancient phylogenetic development and functions relevant for animal survival. Local cells receive intrinsic amygdaloidal information that codes emotional stimuli of fear, integrate them, and send cortical and subcortical output projections that prompt rapid visceral and social behavior responses. We aimed to describe the morphology of the neurons that compose the human CeA (N = 8 adult men). Cells within CeA coronal borders were identified using the thionine staining and were further analyzed using the "single-...
Source: Cell Research - April 17, 2024 Category: Cytology Authors: Carlos E V ásquez K étlyn T Knak Guerra Josu é Renner Alberto A Rasia-Filho Source Type: research
Theta-burst rTMS in schizophrenia to ameliorate negative and cognitive symptoms: study protocol for a double-blind, sham-controlled, randomized clinical trial
Treatment effects of conventional approaches with antipsychotics or psychosocial interventions are limited when it comes to reducing negative and cognitive symptoms in schizophrenia. While there is emerging cl... (Source: Trials)
Source: Trials - April 17, 2024 Category: General Medicine Authors: G ábor Csukly, Boglárka Orbán-Szigeti, Karolin Suri, Réka Zsigmond, Levente Hermán, Viktória Simon, Anita Kabaji, Barnabás Bata, Péter Hársfalvi, Edit Vass, Éva Csibri, Kinga Farkas and János Réthelyi Tags: Study protocol Source Type: research
Simultaneous EEG-fMRI Investigation of Rhythm-Dependent Thalamo-Cortical Circuits Alteration in Schizophrenia
This study aims to provide new insight into network communication in schizophrenia by integrating FC and EEG rhythm information. After collecting simultaneous resting-state EEG-functional magnetic resonance imaging data, the effect of rhythm modulations on FC was explored using what we term "dynamic rhythm information." We also investigated the synergistic relationships among three networks under rhythm modulation conditions, where this relationship presents the coupling between two brain networks with other networks as the center by the rhythm modulation. This study found FC between the thalamus and cortical network regio...
Source: International Journal of Neural Systems - April 16, 2024 Category: Neurology Authors: Haonan Pei Sisi Jiang Mei Liu Guofeng Ye Yun Qin Yayun Liu Mingjun Duan Dezhong Yao Cheng Luo Source Type: research
Multimorbidity and the Etiology of Schizophrenia
Curr Psychiatry Rep. 2024 Apr 16. doi: 10.1007/s11920-024-01500-9. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: A global study of multimorbidity in schizophrenia, especially of the association with physical conditions, might offer much needed etiological insights.RECENT FINDINGS: Our review suggests that life-style factors and medication related to schizophrenia are only part of the explanation of the increase in risk for cardiovascular, metabolic, pulmonary disorders, and some cancers. Positive associations with autoimmune disorders (with the exception of rheumatoid arthritis) and epilepsy are promising avenues of res...
Source: Epilepsy Curr - April 16, 2024 Category: Neurology Authors: A Szoke B Pignon O Godin A Ferchiou R Tamouza M Leboyer F Sch ürhoff Source Type: research
Simultaneous EEG-fMRI Investigation of Rhythm-Dependent Thalamo-Cortical Circuits Alteration in Schizophrenia
This study aims to provide new insight into network communication in schizophrenia by integrating FC and EEG rhythm information. After collecting simultaneous resting-state EEG-functional magnetic resonance imaging data, the effect of rhythm modulations on FC was explored using what we term "dynamic rhythm information." We also investigated the synergistic relationships among three networks under rhythm modulation conditions, where this relationship presents the coupling between two brain networks with other networks as the center by the rhythm modulation. This study found FC between the thalamus and cortical network regio...
Source: International Journal of Neural Systems - April 16, 2024 Category: Neurology Authors: Haonan Pei Sisi Jiang Mei Liu Guofeng Ye Yun Qin Yayun Liu Mingjun Duan Dezhong Yao Cheng Luo Source Type: research
Multimorbidity and the Etiology of Schizophrenia
Curr Psychiatry Rep. 2024 Apr 16. doi: 10.1007/s11920-024-01500-9. Online ahead of print.ABSTRACTPURPOSE OF REVIEW: A global study of multimorbidity in schizophrenia, especially of the association with physical conditions, might offer much needed etiological insights.RECENT FINDINGS: Our review suggests that life-style factors and medication related to schizophrenia are only part of the explanation of the increase in risk for cardiovascular, metabolic, pulmonary disorders, and some cancers. Positive associations with autoimmune disorders (with the exception of rheumatoid arthritis) and epilepsy are promising avenues of res...
Source: Epilepsy Curr - April 16, 2024 Category: Neurology Authors: A Szoke B Pignon O Godin A Ferchiou R Tamouza M Leboyer F Sch ürhoff Source Type: research
Simultaneous EEG-fMRI Investigation of Rhythm-Dependent Thalamo-Cortical Circuits Alteration in Schizophrenia
This study aims to provide new insight into network communication in schizophrenia by integrating FC and EEG rhythm information. After collecting simultaneous resting-state EEG-functional magnetic resonance imaging data, the effect of rhythm modulations on FC was explored using what we term "dynamic rhythm information." We also investigated the synergistic relationships among three networks under rhythm modulation conditions, where this relationship presents the coupling between two brain networks with other networks as the center by the rhythm modulation. This study found FC between the thalamus and cortical network regio...
Source: International Journal of Neural Systems - April 16, 2024 Category: Neurology Authors: Haonan Pei Sisi Jiang Mei Liu Guofeng Ye Yun Qin Yayun Liu Mingjun Duan Dezhong Yao Cheng Luo Source Type: research
