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Specialty: Geriatrics

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Total 1481 results found since Jan 2013.

Burdens on caregivers of patients with stroke during a pandemic: relationships with support satisfaction, psychological distress, and fear of COVID-19
Caregivers have faced unprecedented circumstances throughout the COVID-19 pandemic, but previous research only minimally addresses the caregivers' burden. Therefore, this study aimed to investigate the relatio...
Source: BMC Geriatrics - December 13, 2022 Category: Geriatrics Authors: Chieh-hsiu Liu, Yi-Jung Chen, Jung-Sheng Chen, Chia-Wei Fan, Meng-Tsang Hsieh, Chung-Ying Lin and Amir H. Pakpour Tags: Research Source Type: research

Longitudinal brain age prediction and cognitive function after stroke
Neurobiol Aging. 2022 Oct 29;122:55-64. doi: 10.1016/j.neurobiolaging.2022.10.007. Online ahead of print.NO ABSTRACTPMID:36502572 | DOI:10.1016/j.neurobiolaging.2022.10.007
Source: Neurobiology of Aging - December 11, 2022 Category: Geriatrics Authors: Eva B Aamodt Dag Aln æs Ann-Marie G de Lange Stina Aam Till Schellhorn Ingvild Saltvedt Mona K Beyer Lars T Westlye Source Type: research

Dose-Response Relationship between Red Blood Cell Distribution Width and In-Hospital Mortality in Oldest Old Patients with Acute Ischemic Stroke
Conclusions: Red blood cell distribution width may be a valuable and simple measure for predicting in-hospital mortality in oldest old patients with acute ischemic stroke.Gerontology
Source: Gerontology - December 5, 2022 Category: Geriatrics Source Type: research

As some hail new antibody treatment for Alzheimer ’s, safety and benefit questions persist
In a packed San Francisco conference room with a celebratory atmosphere, upbeat company representatives and scientists yesterday presented detailed clinical trial data on the first Alzheimer’s treatment shown to clearly, albeit modestly, slow the disease’s normal cognitive decline. The antibody therapy has buoyed a field marked by decades of failures. Now, it appears to be on the cusp of being greenlit by the U.S. Food and Drug Administration (FDA). Yet other researchers warn of potential risks, including brain swelling and brain hemorrhages that were linked to the recently disclosed deaths of two trial participants wh...
Source: Science of Aging Knowledge Environment - December 1, 2022 Category: Geriatrics Source Type: research

Neurological Complications and Consequences of the Novel Coronavirus COVID-19 Infection in Elderly and Senile Patients (Literature Review)
AbstractBased on available publications, the article systematizes information about some forms of lesions of the central nervous system (CNS), their pathogenesis and clinical manifestations in the case of COVID-19. The risk factors, mechanisms of development, diagnostic approach, and the age characteristics of patients with neurological complications of COVID-19 are discussed. The specific mechanisms of the neuroinvasiveness and neurovirulence of the SARS-CoV-2 virus, regardless of the age of patients and the presence of risk factors, lead to systemic damage to the endothelium of small-caliber vessels, generalized thrombov...
Source: Advances in Gerontology - December 1, 2022 Category: Geriatrics Source Type: research

Association between cervical artery dissection and spinal manipulative therapy –a medicare claims analysis
Cervical artery dissection and subsequent ischemic stroke is the most serious safety concern associated with cervical spinal manipulation.
Source: BMC Geriatrics - November 29, 2022 Category: Geriatrics Authors: James M Whedon, Curtis L Petersen, Zhongze Li, William J Schoelkopf, Scott Haldeman, Todd A MacKenzie and Jon D Lurie Tags: Research Source Type: research

Effects of Immersive Virtual Therapy as a Method Supporting Recovery of Depressive Symptoms in Post-Stroke Rehabilitation: Randomized Controlled Trial
Source: Clinical Interventions in Aging - November 23, 2022 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research

Carotid disease, cognition, and aging: time to redefine asymptomatic disease?
AbstractThere is an increasing appreciation of the vascular contributions in the development of age-related cognitive impairment and dementia1,2. Identifying risk and maintaining cognitive health for successful aging is ever relevant in our aging population. Carotid disease, a well-established risk factor for stroke and often a harbinger of other vascular disease states, is also emerging as another vascular risk factor for age-related cognitive decline. When combined with vascular risk factors, the incidence of age-related carotid disease can be as high as 70%3,4. Historically, carotid disease has been dichotomized into tw...
Source: AGE - November 15, 2022 Category: Geriatrics Source Type: research

Pressure pain threshold and somatosensory abnormalities in different ages and functional conditions of post-stroke elderly
Somatosensory deficits and abnormal pain sensitivity are highly prevalent among stroke survivors, which negatively impacts their quality of life and recovery process. However, the factors for pressure pain thr...
Source: BMC Geriatrics - October 28, 2022 Category: Geriatrics Authors: Yong-Hui Zhang, Hao-Ran Xu, Yu-Chen Wang, Gong-Wei Hu, Xiao-Qin Ding, Xiao-Hua Shen, Hui Yang, Ji-Feng Rong and Xue-Qiang Wang Tags: Research Source Type: research

Strengths and Weaknesses of the Vascular Apathy Hypothesis: A Narrative Review
Am J Geriatr Psychiatry. 2022 Oct 1:S1064-7481(22)00526-7. doi: 10.1016/j.jagp.2022.09.016. Online ahead of print.ABSTRACTThe vascular apathy hypothesis states that cerebral small vessel disease (CSVD) can cause apathy, even when no other symptoms of CSVD are present. In order to examine this hypothesis, the objectives of this narrative review are to evaluate the evidence for a pathophysiological mechanism linking CSVD to apathy and to examine whether CSVD can be a sole cause of apathy. The nature of the CSVD-apathy relationship was evaluated using the Bradford Hill criteria as a method for research on the distinction betw...
Source: Am J Geriatr Psychia... - October 25, 2022 Category: Geriatrics Authors: Lonneke Wouts Radboud M Marijnissen Richard C Oude Voshaar Aartjan T F Beekman Source Type: research

Invited commentary: The vascular apathy hypothesis and its meaning for clinicians
For geriatric psychiatrists, apathy is one of the most challenging syndromes to diagnose and treat. Although it is a common syndrome characterized by a lack of motivation1, it is striking to observe how frequently apathy is missed or misdiagnosed in clinical settings. It often underlies treatment resistance, which can leave patients, caregivers, and clinicians feeling frustrated with a perceived lack of progress. Apathy is the most common neuropsychiatric symptom of dementia, but it is also seen in numerous neurological diseases including stroke and Parkinson's disease, and it may co-occur with depression.
Source: The American Journal of Geriatric Psychiatry - October 22, 2022 Category: Geriatrics Authors: Stephanie Collier Tags: Editorial Source Type: research

The Vascular Apathy Hypothesis and Its Meaning for Clinicians
For geriatric psychiatrists, apathy is one of the most challenging syndromes to diagnose and treat. Although it is a common syndrome characterized by a lack of motivation,1 it is striking to observe how frequently apathy is missed or misdiagnosed in clinical settings. It often underlies treatment resistance, which can leave patients, caregivers, and clinicians feeling frustrated with a perceived lack of progress. Apathy is the most common neuropsychiatric symptom of dementia, but it is also seen in numerous neurological diseases including stroke and Parkinson's disease, and it may co-occur with depression.
Source: The American Journal of Geriatric Psychiatry - October 22, 2022 Category: Geriatrics Authors: Stephanie Collier Tags: Editorial Source Type: research