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Specialty: Geriatrics

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Total 1481 results found since Jan 2013.

Influence of atrial fibrillation subtypes on anticoagulant therapy in a high-risk older population: the FAI project
CONCLUSIONS: In a population-based survey, AF pattern was an independent predictor of OAC treatment. Paroxysmal AF is still perceived as carrying a lower risk of vascular events.PMID:35543807 | DOI:10.1007/s40520-022-02140-w
Source: Aging Clinical and Experimental Research - May 11, 2022 Category: Geriatrics Authors: Antonio Di Carlo Fabio Mori Domenico Consoli Leonardo Bellino Augusto Zaninelli Marzia Baldereschi Maria Grazia D'Alfonso Chiara Gradia Alessandro Cattarinussi Bruno Sgherzi Giovanni Pracucci Benedetta Piccardi Bianca Maria Polizzi Domenico Inzitari Natio Source Type: research

A Dynamic Nomogram to Identify Patients at High Risk of Poor Outcome in Stroke Patients with Chronic Kidney Disease
Source: Clinical Interventions in Aging - May 9, 2022 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research

Factors Influencing Post-Stroke Cognitive Impairment in Patients with Type 2 Diabetes Mellitus
Source: Clinical Interventions in Aging - April 28, 2022 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research

Stringent public health measures during COVID-19 across ischemic stroke care systems: the potential impact of patient perceptions on health care-seeking behaviors
AbstractDecreases in acute stroke presentations have been reported during the coronavirus disease 2019 (COVID-19) pandemic surges. A recent study by Bojti et al. (GeroScience. 2021;43:2231 –2248) sought to understand the relationship of public health mandates in Hungary as they were implemented with acute ischemic stroke admissions and interventions during two separate COVID-19 waves. We sought to perform a similar analysis of changes in ischemic stroke care at two distinct medical institutions in the USA. Two separate institutions and systems of ischemic stroke care were evaluated through a regional comprehensive stroke...
Source: AGE - April 25, 2022 Category: Geriatrics Source Type: research

Imaging subtle leaks in the blood –brain barrier in the aging human brain: potential pitfalls, challenges, and possible solutions
AbstractRecent studies using dynamic contrast-enhanced magnetic resonance imaging (DCE-MRI) with gadolinium-based contrast agents (GBCA) have demonstrated subtle blood –brain barrier (BBB) leaks in the human brain during normal aging, in individuals with age-related cognitive dysfunction, genetic risk for Alzheimer’s disease (AD), mild cognitive impairment, early AD, cerebral small vessel disease (SVD), and other neurodegenerative disorders. In these neurologi cal conditions, the BBB leaks, quantified by the unidirectional BBB GBCA tracer’s constantKtrans maps, are typically orders of magnitude lower than in brain tu...
Source: AGE - April 25, 2022 Category: Geriatrics Source Type: research

Relationship of Functional Outcome With Sarcopenia and Objectively Measured Physical Activity in Patients With Stroke Undergoing Rehabilitation
This study aimed to investigate the relationship of Functional Independence Measure for motor function (FIM-M) with sarcopenia, and physical activity in patients with stroke undergoing rehabilitation. This cross-sectional study included patients with stroke at a single convalescent rehabilitation hospital. Sarcopenia was diagnosed based on the Asia Working Group for Sarcopenia 2019 criteria. Physical activity was measured as the duration of light-intensity physical activity and moderate to vigorous physical activity using a triaxial accelerometer. Of 80 patients (median age: 72.0 years), 46 (57.5%) were diagnosed with sarc...
Source: Journal of Aging and Physical Activity - April 23, 2022 Category: Geriatrics Authors: Masashi Kanai Masafumi Nozoe Takuro Ohtsubo Iori Yasumoto Katsuhiro Ueno Source Type: research

Movement behavior patterns composition remains stable, but individuals change their movement behavior pattern over time in people with a first-ever stroke
ConclusionsThe composition of movement behavior patterns remains stable over time. However, individuals change their movement behavior. Significantly more people allocated to a movement behavior pattern with higher health risks. The increase of people allocated to sedentary movers and sedentary prolongers is of great concern. It underlines the importance of improving or maintaining healthy movement behavior to prevent future health risks after stroke.
Source: European Review of Aging and Physical Activity - April 22, 2022 Category: Geriatrics Source Type: research

Cannabinoid receptor 2 activation alleviates diabetes-induced cardiac dysfunction, inflammation, oxidative stress, and fibrosis
In this study, we explored the role of CB2R signaling in myocardial dysfunction, oxidative/nitrative stress, inflammation, cell death, remodeling, and fibrosis associated with diabetic cardiomyopathy in type 1 diabetic mice. Control human heart left ventricles and atrial appendages, similarly to mouse hearts, had negligible CB2R expression determine by RNA sequencing or real-time RT-PCR. Diabetic cardiomyopathy was characterized by impaired diastolic and systolic cardiac function, enhanced myocardial CB2R expression, oxidative/nitrative stress, and pro-inflammatory response (tumor necrosis factor- α, interleukin-1β, intr...
Source: AGE - April 22, 2022 Category: Geriatrics Source Type: research

Benefits of Endovascular Treatment in Late Window for Acute Ischemic Stroke Selected without CT Perfusion: A Real-World Study
Source: Clinical Interventions in Aging - April 21, 2022 Category: Geriatrics Tags: Clinical Interventions in Aging Source Type: research

Association between Baseline Cognitive Function and Longitudinal Functional Outcome Change after Ischemic Stroke
Conclusion: After ischemic stroke, higher baseline global cognitive function was a predictive factor for better functional recovery regardless of depression symptoms in the minor stroke group.Dement Geriatr Cogn Disord
Source: Dementia and Geriatric Cognitive Disorders - April 21, 2022 Category: Geriatrics Source Type: research

Prediction of post-stroke cognitive impairment by Montreal Cognitive Assessment (MoCA) performances in acute stroke: comparison of three normative datasets
CONCLUSIONS: The classification of acute stroke patients as normal/impaired based on MoCA thresholds proposed by general population normative datasets underestimated patients at risk of persistent PSCI. We calculated a new adjusted MoCA score predictive of PSCI in acute stroke patients to be further tested in larger studies.PMID:35441928 | DOI:10.1007/s40520-022-02133-9
Source: Aging Clinical and Experimental Research - April 20, 2022 Category: Geriatrics Authors: Emilia Salvadori Ilaria Cova Francesco Mele Simone Pomati Leonardo Pantoni Source Type: research