Prevalence of Cognitive Impairment and Dementia in Older Adults Living at High Altitude: A Systematic Review and Meta-Analysis
Conclusions: The prevalence of cognitive impairment and dementia in older adults living at high altitude is almost twice the number reported in some world regions.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - June 17, 2021 Category: Geriatrics Source Type: research

Online Tool (Brain Assessment) for the Detection of Cognitive Function Changes during Aging
CONCLUSION: The BA can be easily taken online using a PC, and its scores linearly declined with normal aging. The BA will be useful for detecting longitudinal cognitive changes and comparing them to the pattern seen in normal aging.PMID:34126622 | DOI:10.1159/000516564 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - June 14, 2021 Category: Psychiatry Authors: Masayuki Satoh Ken-Ichi Tabei Saiko Fujita Yoshinori Ota Source Type: research

Online Tool (Brain Assessment) for the Detection of Cognitive Function Changes during Aging
Conclusion: The BA can be easily taken online using a PC, and its scores linearly declined with normal aging. The BA will be useful for detecting longitudinal cognitive changes and comparing them to the pattern seen in normal aging.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - June 14, 2021 Category: Geriatrics Source Type: research

Mental and Physical Self-Awareness of Alzheimer Patients: Decreased Awareness of Amnesia and Increased Fear of Falling Compared to Views of Families: The Tajiri and Wakuya Projects
Conclusion: The results showed an evidence of the heterogeneity of awareness, an emotional response (concern or fear, FES), and a cognitive appraisal of function (EMC). These may be explained whereby awareness of/fear of falling increases with AD due to a preserved emotional awareness, whereas awareness of cognitive impairment is impaired due to memory deficits.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - June 8, 2021 Category: Geriatrics Source Type: research

Mental and Physical Self-Awareness of Alzheimer Patients: Decreased Awareness of Amnesia and Increased Fear of Falling Compared to Views of Families: The Tajiri and Wakuya Projects
CONCLUSION: The results showed an evidence of the heterogeneity of awareness, an emotional response (concern or fear, FES), and a cognitive appraisal of function (EMC). These may be explained whereby awareness of/fear of falling increases with AD due to a preserved emotional awareness, whereas awareness of cognitive impairment is impaired due to memory deficits.PMID:34102642 | DOI:10.1159/000516656 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - June 8, 2021 Category: Psychiatry Authors: Keiichi Kumai Nobuko Kawabata Kenichi Meguro Junko Takada Kei Nakamura Satoshi Yamaguchi Source Type: research

Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer ’s and Parkinson’s Disease Patients
Conclusions: These results suggest a link between leukocytosis and the pathophysiology of cognitive dysfunction in both PD and AD. A better understanding of the role of systemic neuroinflammation on these devastating neurodegenerative disorders may facilitate the development of cost-effective blood biomarkers for patient ’s early diagnosis and more accurate prognosis.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 31, 2021 Category: Geriatrics Source Type: research

Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer's and Parkinson's Disease Patients
CONCLUSIONS: These results suggest a link between leukocytosis and the pathophysiology of cognitive dysfunction in both PD and AD. A better understanding of the role of systemic neuroinflammation on these devastating neurodegenerative disorders may facilitate the development of cost-effective blood biomarkers for patient's early diagnosis and more accurate prognosis.PMID:34058741 | DOI:10.1159/000516340 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 31, 2021 Category: Psychiatry Authors: Santiago R Unda Aldana M Antoniazzi David J Altschul Roberta Marongiu Source Type: research

Sex Differences on Montreal Cognitive Assessment and Mini-Mental State Examination Scores and the Value of Self-Report of Memory Problems among Community Dwelling People 70 Years and above: The HUNT Study
CONCLUSIONS: The MoCA score was associated with sex, age, and education, whereas sex did not influence the MMSE score. The question "have you experienced significant memory problems the last 5 years?" may be useful to evaluate older people's cognition.PMID:34038905 | DOI:10.1159/000516341 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 26, 2021 Category: Psychiatry Authors: Knut Engedal Linda Gj øra Thea Bredholt Pernille Thingstad Gro Gujord Tangen Linda Ernstsen Geir Selb æk Source Type: research

Sex Differences on Montreal Cognitive Assessment and Mini-Mental State Examination Scores and the Value of Self-Report of Memory Problems among Community Dwelling People 70 Years and above: The HUNT Study
Conclusions: The MoCA score was associated with sex, age, and education, whereas sex did not influence the MMSE score. The question “have you experienced significant memory problems the last 5 years?” may be useful to evaluate older people’s cognition.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 26, 2021 Category: Geriatrics Source Type: research

Sporadic Creutzfeldt-Jakob Disease: Diagnosing Typical and Atypical Presentations under Limited Circumstances
CONCLUSION: Even with limited testing available, the diagnosis of CJD can be made with confidence in the developing countries, provided the suspicion is kept high in cases of rapid onset dementia and acute behavioral changes.PMID:34023835 | DOI:10.1159/000514470 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 23, 2021 Category: Psychiatry Authors: Shazma Khan Sara Khan Source Type: research

Sporadic Creutzfeldt-Jakob Disease: Diagnosing Typical and Atypical Presentations under Limited Circumstances
Conclusion: Even with limited testing available, the diagnosis of CJD can be made with confidence in the developing countries, provided the suspicion is kept high in cases of rapid onset dementia and acute behavioral changes.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 21, 2021 Category: Geriatrics Source Type: research

Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology
CONCLUSION: Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy.PMID:33975314 | DOI:10.1159/000515678 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 11, 2021 Category: Psychiatry Authors: Clare Burgon Sarah Elizabeth Goldberg Veronika van der Wardt Catherine Brewin Rowan H Harwood Source Type: research

Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology
Conclusion: Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 11, 2021 Category: Geriatrics Source Type: research

The Effects of Aerobic Exercise in Patients with Early-Onset Dementia: A Scoping Review
Dement Geriatr Cogn Disord. 2021 May 6:1-8. doi: 10.1159/000516231. Online ahead of print.ABSTRACTBACKGROUND: Early-onset dementia (EOD) defines all dementia related conditions with an onset before the age of 65 years. EOD places a large and distressing psychological, emotional and financial burden on the individuals themselves and their caregivers. For various reasons, diagnostic and treatment strategies for EOD are very challenging. There is a general agreement that not only the human body but also the mind benefits from physical activity and/or exercise. Especially aerobic exercise has shown to have favorable effects on...
Source: Dementia and Geriatric Cognitive Disorders - May 6, 2021 Category: Psychiatry Authors: Tine Roman de Mettelinge Patrick Calders Dirk Cambier Source Type: research

The Effects of Aerobic Exercise in Patients with Early-Onset Dementia: A Scoping Review
Background: Early-onset dementia (EOD) defines all dementia related conditions with an onset before the age of 65 years. EOD places a large and distressing psychological, emotional and financial burden on the individuals themselves and their caregivers. For various reasons, diagnostic and treatment strategies for EOD are very challenging. There is a general agreement that not only the human body but also the mind benefits from physical activity and/or exercise. Especially aerobic exercise has shown to have favorable effects on cognitive functions in healthy older adults, as well as in patients with MCI and dementia. Howeve...
Source: Dementia and Geriatric Cognitive Disorders - May 6, 2021 Category: Geriatrics Source Type: research

Physical Frailty and Cognitive Impairment in Older Adults in United States Nursing Homes
Conclusion: Physical frailty was prevalent in NHs with potential to improve and was strongly associated with cognitive impairment. Physical frailty could be a modifiable target, and interventions may include efforts to address cognitive impairment.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - April 22, 2021 Category: Geriatrics Source Type: research

Physical Frailty and Cognitive Impairment in Older Adults in United States Nursing Homes
CONCLUSION: Physical frailty was prevalent in NHs with potential to improve and was strongly associated with cognitive impairment. Physical frailty could be a modifiable target, and interventions may include efforts to address cognitive impairment.PMID:33887723 | DOI:10.1159/000515140 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - April 22, 2021 Category: Psychiatry Authors: Yiyang Yuan Kate L Lapane Jennifer Tjia Jonggyu Baek Shao-Hsien Liu Christine M Ulbricht Source Type: research