Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer ’s and Parkinson’s Disease Patients
Conclusions: These results suggest a link between leukocytosis and the pathophysiology of cognitive dysfunction in both PD and AD. A better understanding of the role of systemic neuroinflammation on these devastating neurodegenerative disorders may facilitate the development of cost-effective blood biomarkers for patient ’s early diagnosis and more accurate prognosis.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 31, 2021 Category: Geriatrics Source Type: research

Peripheral Leukocytosis Predicts Cognitive Decline but Not Behavioral Disturbances: A Nationwide Study of Alzheimer's and Parkinson's Disease Patients
CONCLUSIONS: These results suggest a link between leukocytosis and the pathophysiology of cognitive dysfunction in both PD and AD. A better understanding of the role of systemic neuroinflammation on these devastating neurodegenerative disorders may facilitate the development of cost-effective blood biomarkers for patient's early diagnosis and more accurate prognosis.PMID:34058741 | DOI:10.1159/000516340 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 31, 2021 Category: Psychiatry Authors: Santiago R Unda Aldana M Antoniazzi David J Altschul Roberta Marongiu Source Type: research

Sex Differences on Montreal Cognitive Assessment and Mini-Mental State Examination Scores and the Value of Self-Report of Memory Problems among Community Dwelling People 70 Years and above: The HUNT Study
CONCLUSIONS: The MoCA score was associated with sex, age, and education, whereas sex did not influence the MMSE score. The question "have you experienced significant memory problems the last 5 years?" may be useful to evaluate older people's cognition.PMID:34038905 | DOI:10.1159/000516341 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 26, 2021 Category: Psychiatry Authors: Knut Engedal Linda Gj øra Thea Bredholt Pernille Thingstad Gro Gujord Tangen Linda Ernstsen Geir Selb æk Source Type: research

Sex Differences on Montreal Cognitive Assessment and Mini-Mental State Examination Scores and the Value of Self-Report of Memory Problems among Community Dwelling People 70 Years and above: The HUNT Study
Conclusions: The MoCA score was associated with sex, age, and education, whereas sex did not influence the MMSE score. The question “have you experienced significant memory problems the last 5 years?” may be useful to evaluate older people’s cognition.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 26, 2021 Category: Geriatrics Source Type: research

Sporadic Creutzfeldt-Jakob Disease: Diagnosing Typical and Atypical Presentations under Limited Circumstances
CONCLUSION: Even with limited testing available, the diagnosis of CJD can be made with confidence in the developing countries, provided the suspicion is kept high in cases of rapid onset dementia and acute behavioral changes.PMID:34023835 | DOI:10.1159/000514470 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 23, 2021 Category: Psychiatry Authors: Shazma Khan Sara Khan Source Type: research

Sporadic Creutzfeldt-Jakob Disease: Diagnosing Typical and Atypical Presentations under Limited Circumstances
Conclusion: Even with limited testing available, the diagnosis of CJD can be made with confidence in the developing countries, provided the suspicion is kept high in cases of rapid onset dementia and acute behavioral changes.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 21, 2021 Category: Geriatrics Source Type: research

Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology
CONCLUSION: Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy.PMID:33975314 | DOI:10.1159/000515678 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 11, 2021 Category: Psychiatry Authors: Clare Burgon Sarah Elizabeth Goldberg Veronika van der Wardt Catherine Brewin Rowan H Harwood Source Type: research

Apathy Measures in Older Adults and People with Dementia: A Systematic Review of Measurement Properties Using the COSMIN Methodology
Conclusion: Numerous scales are available to assess apathy, with varying psychometric properties. The AES and LARS are recommended for measuring apathy in older adults and people living with dementia. The apathy dimension of the commonly used Neuropsychiatric Inventory should be limited to screening for apathy.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - May 11, 2021 Category: Geriatrics Source Type: research

The Effects of Aerobic Exercise in Patients with Early-Onset Dementia: A Scoping Review
Dement Geriatr Cogn Disord. 2021 May 6:1-8. doi: 10.1159/000516231. Online ahead of print.ABSTRACTBACKGROUND: Early-onset dementia (EOD) defines all dementia related conditions with an onset before the age of 65 years. EOD places a large and distressing psychological, emotional and financial burden on the individuals themselves and their caregivers. For various reasons, diagnostic and treatment strategies for EOD are very challenging. There is a general agreement that not only the human body but also the mind benefits from physical activity and/or exercise. Especially aerobic exercise has shown to have favorable effects on...
Source: Dementia and Geriatric Cognitive Disorders - May 6, 2021 Category: Psychiatry Authors: Tine Roman de Mettelinge Patrick Calders Dirk Cambier Source Type: research

The Effects of Aerobic Exercise in Patients with Early-Onset Dementia: A Scoping Review
Background: Early-onset dementia (EOD) defines all dementia related conditions with an onset before the age of 65 years. EOD places a large and distressing psychological, emotional and financial burden on the individuals themselves and their caregivers. For various reasons, diagnostic and treatment strategies for EOD are very challenging. There is a general agreement that not only the human body but also the mind benefits from physical activity and/or exercise. Especially aerobic exercise has shown to have favorable effects on cognitive functions in healthy older adults, as well as in patients with MCI and dementia. Howeve...
Source: Dementia and Geriatric Cognitive Disorders - May 6, 2021 Category: Geriatrics Source Type: research

Physical Frailty and Cognitive Impairment in Older Adults in United States Nursing Homes
Conclusion: Physical frailty was prevalent in NHs with potential to improve and was strongly associated with cognitive impairment. Physical frailty could be a modifiable target, and interventions may include efforts to address cognitive impairment.Dement Geriatr Cogn Disord (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - April 22, 2021 Category: Geriatrics Source Type: research

Physical Frailty and Cognitive Impairment in Older Adults in United States Nursing Homes
CONCLUSION: Physical frailty was prevalent in NHs with potential to improve and was strongly associated with cognitive impairment. Physical frailty could be a modifiable target, and interventions may include efforts to address cognitive impairment.PMID:33887723 | DOI:10.1159/000515140 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - April 22, 2021 Category: Psychiatry Authors: Yiyang Yuan Kate L Lapane Jennifer Tjia Jonggyu Baek Shao-Hsien Liu Christine M Ulbricht Source Type: research

Hyposmia Is Associated with Reduced Cognitive Function in COVID-19: First Preliminary Results
CONCLUSION: OD is associated with cognitive impairment in controls and mild COVID-19. OD may represent a potentially useful clinical biomarker for subtle and even subclinical neurological involvement in severe acute respiratory distress syndrome coronavirus-2 infection.PMID:33853062 | DOI:10.1159/000515575 (Source: Dementia and Geriatric Cognitive Disorders)
Source: Dementia and Geriatric Cognitive Disorders - April 14, 2021 Category: Psychiatry Authors: Agnes Pirker-Kees Kirsten Platho-Elwischger Sebastian Hafner Kurt Redlich Christoph Baumgartner Source Type: research