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Specialty: Geriatrics

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Total 1481 results found since Jan 2013.

Can subjective cognitive complaints at three months post stroke predict alteration in information processing speed during the first year?
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Source: Aging, Neuropsychology, and Cognition - March 6, 2022 Category: Geriatrics Authors: Sonja Verstraeten Anne Berkhoff Ruth Mark Margriet Sitskoorn Source Type: research

The humble worrier - the long-term impact of using yoga to treat severe worry and anxiety in older adults
Over the last decade, multiple reports have signaled the association of late-life anxiety and its phenotypes with increased morbidity and mortality. A 2014 study of 6,019 participants showed that higher anxiety symptoms were prospectively associated with increased risk of incident stroke independent of all other risk factors, including depression (1). The independent effect of anxiety on increasing the risk of cognitive decline has been documented in several recent studies (2), including longitudinal studies indicating an increased association between amyloid burden and anxiety symptoms in cognitively normal older adults (3).
Source: The American Journal of Geriatric Psychiatry - February 26, 2022 Category: Geriatrics Authors: Carmen Andreescu Tags: Editorial Source Type: research

Is Frailty Index a better predictor than pre-stroke modified Rankin Scale for neurocognitive outcomes 3-months post-stroke?
The prognostic value of frailty measures for post-stroke neurocognitive disorder (NCD) remains to be evaluated.
Source: BMC Geriatrics - February 19, 2022 Category: Geriatrics Authors: Ragnhild Munthe-Kaas, Stina Aam, Ingvild Saltvedt, Torgeir Bruun Wyller, Sarah T. Pendlebury, Stian Lydersen, Guri Hagberg, Till Schellhorn, Siri Rostoft and Hege Ihle-Hansen Tags: Research Source Type: research

SARS-CoV-2 interacts with renin-angiotensin system: impact on the central nervous system in elderly patients
AbstractSARS-CoV-2 is a recently identified coronavirus that causes the current pandemic disease known as COVID-19. SARS-CoV-2 uses angiotensin-converting enzyme 2 (ACE2) as a receptor, suggesting that the initial steps of SARS-CoV-2 infection may have an impact on the renin-angiotensin system (RAS). Several processes are influenced by RAS in the brain. The neurological symptoms observed in COVID-19 patients, including reduced olfaction, meningitis, ischemic stroke, cerebral thrombosis, and delirium, could be associated with RAS imbalance. In this review, we focus on the potential role of disturbances in the RAS as a cause...
Source: AGE - February 14, 2022 Category: Geriatrics Source Type: research

Understanding the relationship between perceived discrimination and mortality in United States adults
CONCLUSIONS: Adults experiencing lifetime and daily discrimination had significantly increased risk of mortality after adjusting for predisposing, enabling, and need factors. The findings highlight the importance of screening patients during clinical encounters for experiences of discrimination and providing appropriate resources to mitigate the negative impact of discriminatory events on mortality. Future research should work to fully understand the mechanism by which discrimination increases risk of mortality. These future findings should be used to develop targets for interventions designed to decrease mortality among a...
Source: Aging and Mental Health - February 4, 2022 Category: Geriatrics Authors: Joanna O Obaoye Aprill Z Dawson Madhuli Thakkar Joni S Williams Leonard E Egede Source Type: research

The impact of micronized progesterone on cardiovascular events - a systematic review
In conclusion, while available data suggest that MP as a component in combined MHT may have a neutral effect on the vascular system, more RCTs investigating the impact of MP alone or in combined MHT on vascular primary endpoints are needed.PMID:35112635 | DOI:10.1080/13697137.2021.2022644
Source: Climacteric - February 3, 2022 Category: Geriatrics Authors: L M Kaemmle A Stadler H Janka M von Wolff P Stute Source Type: research

Hippocampus is more susceptible to hypoxic injury: has the Rosetta Stone of regional variation in neurovascular coupling been deciphered?
AbstractAlzheimer ’s disease and Alzheimer’s disease–related dementias (AD/ADRD) are associated with cerebral hypoperfusion or reductions in baseline cerebral blood flow (CBF). The neurovascular coupling (NVC) response or functional hyperemia regulates brain perfusion via a retrograde (capillary-to-arteriole) p athway by increasing regional CBF in response to local neuron activation. The hippocampus plays a significant role in spatial and non-spatial memory. Functional MRI (fMRI) has not established a solid positive correlation between hippocampal blood oxygen level–dependent (BOLD) signal and local neur onal activ...
Source: AGE - February 1, 2022 Category: Geriatrics Source Type: research