Cognitive behavioral therapy for menopausal symptoms.
This article describes cognitive behavioral therapy (CBT) for women with problematic menopausal symptoms, and provides the evidence from clinical trials of women going through the menopause, women with breast cancer treatment-induced symptoms and women with problematic symptoms in a work context. The CBT focus is primarily on vasomotor symptoms (VMS) but it also targets stress, low mood and sleep problems. CBT is a brief therapy (four to six sessions) that is theory- and evidence-based; it is acceptable to women and effectively reduces the impact of VMS, improves sleep and has benefits to quality of life. VMS frequency is ...
Source: Climacteric - July 6, 2020 Category: Geriatrics Authors: Hunter MS Tags: Climacteric Source Type: research

Follicle stimulating hormone and estradiol trajectories from menopausal transition to late postmenopause in indigenous Chinese women.
Conclusions: The FSH and E2 trajectories in this indigenous Chinese cohort appear similar to those discussed in the Study of Women's Health Across the Nation, with ethnic differences. STRAW + 10 criteria may be used to ascertain the ovarian aging process in Chinese women. Obese women may experience different levels of hormonal fluctuations during the menopause transition, while FSH levels in all women appear to remain high even at late postmenopause. PMID: 32627598 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - July 6, 2020 Category: Geriatrics Authors: Wang Y, Tang R, Luo M, Sun X, Li J, Yue Y, Liu G, Lin S, Chen R Tags: Climacteric Source Type: research

Inverse association between bone mineral density and fibrinogen in menopausal women.
Abstract Objective: Inflammatory diseases are risk factors for osteoporosis. We aimed to explore whether fibrinogen, which is linked to chronic inflammation, is associated with bone mineral density (BMD) in menopausal women.Methods: In this cross-sectional study, we analyzed 339 menopausal women from Zhejiang Province between January 2016 and October 2019. Linear regression analysis was performed to assess the relationship between fibrinogen and BMD.Results: Significant inverse association was observed between the serum fibrinogen level and BMD in menopausal women. The mean BMD in each quartile of fibrinogen level...
Source: Climacteric - June 30, 2020 Category: Geriatrics Authors: Chen YJ, Wang X, Zhang HY, Du YN, Jin XJ, Zhang ZF Tags: Climacteric Source Type: research

ACTN3 R577X polymorphism related to sarcopenia and physical fitness in active older women.
Conclusions: Sarcopenia and physical fitness show differences based on the ACTN3 R577X genotype in active older women. PMID: 32602369 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 30, 2020 Category: Geriatrics Authors: Romero-Blanco C, Artiga González MJ, Gómez-Cabello A, Vila-Maldonado S, Casajús JA, Ara I, Aznar S Tags: Climacteric Source Type: research

The association between vitamin D receptor FokI gene polymorphism and osteoporosis in postmenopausal women: a meta-analysis.
This study aimed to quantitatively summarize the evidence for vitamin D receptor (VDR) FokI gene polymorphism and osteoporosis risk in Caucasian and Asian postmenopausal women.Materials and methods: The PubMed, EMBASE, Weipu, CNKI, and Wanfang databases were searched for eligible studies. Case-control studies containing available genotype frequencies for F/f were chosen, and the odds ratio (OR) with 95% confidence interval (CI) was used to assess the strength of this association.Results: In total, 3349 osteoporosis cases and 3202 controls were identified in our meta-analysis. In the stratified analysis, a significant assoc...
Source: Climacteric - June 18, 2020 Category: Geriatrics Authors: Wang S, Ai Z, Song M, Yan P, Li J, Wang S Tags: Climacteric Source Type: research

The impact of menopausal hormone therapy on overall mortality - a comprehensive review.
Abstract Menopausal hormone therapy (MHT) is indicated for menopausal symptom relief. However, MHT has also been shown to be beneficial for prevention of long-term estrogen deficiency sequelae including mortality. Based on a comprehensive literature review on MHT and mortality, the authors' recommendations are as follows: in postmenopausal women, MHT appears to confer a (significant) reduction in overall mortality; the benefit especially applies to women who initiate long-term MHT early after menopause; in women with prevalent cardiovascular risk factors (except for diabetes mellitus, where results are mixed), the...
Source: Climacteric - June 18, 2020 Category: Geriatrics Authors: Stute P, Stadler A, Heufelder A Tags: Climacteric Source Type: research

Doppler ultrasonography of the ophthalmic artery in perimenopausal and postmenopausal women: a new approach.
Conclusions: There is a positive correlation between the SDR and age in the control group. Therefore, this new index is a promising instrument in the non-invasive assessment of cardiovascular risk. PMID: 32552263 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 18, 2020 Category: Geriatrics Authors: Saramago ALP, Diniz ALD Tags: Climacteric Source Type: research

Attitude and knowledge for menopause management among health professionals in mainland China.
Conclusion: This survey indicated that HPs have some knowledge regarding MM, but a gap remains to master the basic theory of MHT. In order to manage the growing menopausal population in China, creating more in-depth educational MMT programs for HPs is necessary. PMID: 32543223 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 16, 2020 Category: Geriatrics Authors: Lin L, Feng P, Yu Q Tags: Climacteric Source Type: research

An extended Menopause Rating Scale II: a retrospective data analysis.
Conclusion: We suggest including the items 'changes in weight', 'headaches', and 'skin changes' in the MRS II as our results show even higher internal consistency with these symptoms and as the wish for therapy was high. PMID: 32543231 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 16, 2020 Category: Geriatrics Authors: Honermann L, Knabben L, Weidlinger S, Bitterlich N, Stute P Tags: Climacteric Source Type: research

Factors of mineral homeostasis impairment and bone mineral density loss in women with central hypogonadism.
Conclusion: Central hypogonadism at a young age poses a higher risk of bone metabolism impairment than physiological menopause. PMID: 32519580 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 10, 2020 Category: Geriatrics Authors: Ilovayskaya I, Zektser V, Lazebnik L Tags: Climacteric Source Type: research

An overview of the main intrauterine pathologies in the postmenopausal period.
Abstract Hysteroscopy is the gold standard for evaluating the uterine cavity, diagnosing intrauterine pathology, and operative intervention for some causes of abnormal uterine bleeding. The American College of Obstetricians and Gynecologists concluded that, when the endometrium measures ≤4 mm with transvaginal ultrasonography, the likelihood that bleeding is secondary to endometrial carcinoma is less than 1% (negative predictive value 99%), and endometrial biopsy is not recommended. Endometrial sampling in this clinical scenario will likely result in insufficient tissue for evaluation and it is reasonabl...
Source: Climacteric - June 10, 2020 Category: Geriatrics Authors: Manchanda R, Thapa S Tags: Climacteric Source Type: research

Ovarian tissue cryopreservation and transplantation prevents iatrogenic premature ovarian insufficiency: first 10 cases in China.
Conclusion: Regarding ovarian function, OTC and OTCT were successful and reliable in China's first cryobank. We expect to perform more retransplantations in the near future, which will add to the global data. PMID: 32508143 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - June 8, 2020 Category: Geriatrics Authors: Ruan X, Cheng J, Korell M, Du J, Kong W, Lu D, Wu Y, Li Y, Jin F, Gu M, Duan W, Dai Y, Yin C, Yan S, Mueck AO Tags: Climacteric Source Type: research

To treat or not to treat? An evidence-based practice guide for the management of endometrial polyps.
Abstract Endometrial polyps are a common finding, with a prevalence of about 40%, and are usually diagnosed incidentally as most are asymptomatic. Symptomatic polyps usually present with abnormal uterine bleeding and/or sub-fertility. About 25% of polyps resolve spontaneously if managed conservatively. The usual management of endometrial polyps, symptomatic or asymptomatic, is polypectomy, performed primarily to exclude malignancy within the polyp despite the overall risk of malignancy being low (about 3%). The main risk factors for malignancy are menopause and abnormal uterine bleeding, with hypertension, obesity...
Source: Climacteric - June 4, 2020 Category: Geriatrics Authors: Sheng KK, Lyons SD Tags: Climacteric Source Type: research

Health information needs of 1000 midlife Singaporean women.
Abstract Objectives: Due to demographic changes, aging is a health priority. We aimed to identify midlife women's perceived health information needs and the preferred method(s) of information delivery.Methods: A questionnaire was offered to women, aged 45-69 years, attending gynecological clinics during April/May 2016, collecting age and ethnicity data. Participants were asked to indicate important midlife health topics out of 26 topics, including 'other'. For each topic, six delivery options were offered. Age was stratified by 5-year intervals. Associations with age and ethnicity were examined using Pearso...
Source: Climacteric - June 4, 2020 Category: Geriatrics Authors: Wong JLJ, Thu WPP, Lim CW, Wang WL, Yong EL, Logan SJS Tags: Climacteric Source Type: research

Pandemics: learning from the past.
PMID: 32378449 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - May 8, 2020 Category: Geriatrics Authors: Baber R Tags: Climacteric Source Type: research

Gender differences in the prevalence of vitamin D deficiency in a southern Latin American country: a pilot study.
This study aimed to study the prevalence of vitamin D deficiency, assessing the influence of sex, age, and season of the year.Methods: A cross-sectional study was conducted with 1329 healthy subjects (668 women and 661 men) aged 18-89 years in Santiago, Chile. Age (years), body mass index, medical history, working status, sex, and date of blood sample were collected.Results: Men were slightly older than women (53.1 ± 18.2 vs. 50.0 ± 15.6 years; p 
Source: Climacteric - May 5, 2020 Category: Geriatrics Authors: Vallejo MS, Blümel JE, Arteaga E, Aedo S, Tapia V, Araos A, Sciaraffia C, Castelo-Branco C Tags: Climacteric Source Type: research

Office hysteroscopy in the management of women with postmenopausal bleeding.
Abstract Postmenopausal bleeding (PMB) is a relevant aspect for health-care providers in clinical practice: the first objective is to rule out potential gynecological cancer. The purpose of this narrative review is to evaluate the role of office hysteroscopy in the management of PMB. Office hysteroscopy is a minimally invasive procedure allowing direct visualization of uterine pathology without the need for general anesthesia and the use of an operating room, generating cost savings and greater compliance among patients. Here, we focus on major intrauterine diseases (polyps, submucosal myomas, endometrial hyperpla...
Source: Climacteric - May 5, 2020 Category: Geriatrics Authors: Giampaolino P, Della Corte L, Di Filippo C, Mercorio A, Vitale SG, Bifulco G Tags: Climacteric Source Type: research

Glycine Max (L.) Merr isoflavone gel improves vaginal vascularization in postmenopausal women.
Conclusion: The results showed that local administration of Glycine max (L.) Merr isoflavone gel promoted a significant improvement in the number of blood vessels in the vaginal tissue of postmenopausal women. PMID: 32338067 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 27, 2020 Category: Geriatrics Authors: Lima SMRR, Honorato JV, Silva MALG Tags: Climacteric Source Type: research

Irisin ameliorates bone loss in ovariectomized mice.
Conclusion: Irisin increases osteoblasts and decreases the number of osteoclasts, which leads to the maintenance of bone mass and quality in OVX mice. Irisin likely preserves the bone microarchitecture via building a 'new balance'. Therefore, our study extended the understanding of the role of irisin in bone metabolism and revealed the possibility of therapeutic application of irisin for postmenopausal osteoporosis. PMID: 32319323 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 22, 2020 Category: Geriatrics Authors: Luo Y, Ma Y, Qiao X, Zeng R, Cheng R, Nie Y, Li S, A R, Shen X, Yang M, Xu CC, Xu L Tags: Climacteric Source Type: research

Office hysteroscopy: back to the future!
Abstract Hysteroscopy and anesthesia have come a long way in the last 150 years. While traditionally performed in the operating theater under general anesthesia, the alternative approach - so-called 'office' hysteroscopy - has gained popularity in recent years. Supporters of this modality cite the 'see and treat' capabilities, avoidance of anesthesia, more rapid turn-around time, and favorable economics as advantages. On the other hand, some question the success rate, capabilities, and patient comfort levels as potential drawbacks. In this article, we review the evidence behind all of these points as well a...
Source: Climacteric - April 22, 2020 Category: Geriatrics Authors: Mak JN, Imran A, Burnet S Tags: Climacteric Source Type: research

Objective and subjective vasomotor symptom outcomes in the CBT-Meno randomized controlled trial.
Conclusion: The CBT-Meno trial improved subjective but not objective (physiological) measures of vasomotor symptoms. Self-reported sleep difficulties were unrelated to subjective or objective vasomotor symptoms. PMID: 32299247 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 17, 2020 Category: Geriatrics Authors: Green SM, Donegan E, McCabe RE, Fedorkow DM, Streiner DL, Frey BN Tags: Climacteric Source Type: research

Pain management during diagnostic office hysteroscopy in postmenopausal women: a randomized study.
This study aimed to compare efficacy and safety of lidocaine versus tramadol versus placebo in reducing the pain of diagnostic outpatient hysteroscopy (OH) in postmenopausal women.Materials and methods: This randomized double-blinded study included 156 menopausal women who received intrauterine lidocaine infusion or oral tramadol (50 mg) or placebo before diagnostic OH (52 women/group). Primary outcome was pain severity during the procedure using a 10-cm visual analog scale. Secondary outcomes were pain scores 10 and 30 min post procedure, satisfaction level, and ease of cervical entry.Results: Lidocaine had ...
Source: Climacteric - April 17, 2020 Category: Geriatrics Authors: Samy A, Nabil H, Abdelhakim AM, Mahy ME, Abdel-Latif AA, Metwally AA Tags: Climacteric Source Type: research

Sexual function through decades: association with androgens and cardiometabolic features.
Conclusion: According to our survey, sexual function decreases starting at the age of 30 and continues to drop until the late 60s among postmenopausal women. There was no association between sexual dysfunction and androgen levels in premenopausal women. The serum DHEAS level was associated with sexual dysfunction only among postmenopausal women. There was no association between sexual dysfunction and cardiometabolic features in either premenopausal or postmenopausal women. PMID: 32292081 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 15, 2020 Category: Geriatrics Authors: Yoldemir T, Garibova N, Atasayan K Tags: Climacteric Source Type: research

Association between depressed mood and sexual function among mid-aged Paraguayan women.
Conclusion: In this mid-aged Paraguayan female sample there was a significant association between depressed mood and an increased risk of sexual dysfunction. PMID: 32266841 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 8, 2020 Category: Geriatrics Authors: Sánchez-Zarza SC, Mezones-Holguín E, López-Baena MT, Soto-Becerra P, Pérez-López FR, Gavilanes AWD, Chedraui P Tags: Climacteric Source Type: research

Clinical management of vaginal bleeding in postmenopausal women.
Abstract Menopause is characterized by permanent cessation of menstrual periods and is clinically diagnosed after 12 months of complete amenorrhea. It occurs at a median age of 51 years alongside the physiological process of aging, although it can happen at an earlier age for other medical conditions or after surgery (surgical menopause). Due to reduced circulating estrogens and progesterone, the reproductive organs undergo progressive atrophy. This physiologic process of aging is also present at an endometrial level; without the cyclic hormonal actions of the menstrual cycle, the endometrium during ...
Source: Climacteric - April 1, 2020 Category: Geriatrics Authors: Carugno J Tags: Climacteric Source Type: research

Advertising in medical journals.
PMID: 32020827 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - February 7, 2020 Category: Geriatrics Authors: Baber R Tags: Climacteric Source Type: research

Preventive effects of Polygonum orientale L. on ovariectomy-induced osteoporosis in rats.
Abstract Objective: The aim of the present study was to evaluate the effects of ethyl acetate extract of Polygonum orientale L. (POE) on ameliorating postmenopausal osteoporosis in ovariectomized (OVX) rats.Methods: Six-month-old female rats were randomly divided into seven groups: sham-operated; OVX; OVX with estradiol valerate; OVX with alendronate; and OVX with POE in graded doses (3.75, 5.0, or 7.5 g/kg/day). Administration began at week 6 after ovariectomy for 12 weeks. A comprehensive assessment of bone quality was performed, including serum biochemical markers, serum inflammatory factors, bone...
Source: Climacteric - February 6, 2020 Category: Geriatrics Authors: Ma Y, Zeng R, Hu QQ, Yan HX, Yang LX, Dong Y, Qu Y Tags: Climacteric Source Type: research

Artificial intelligence and women's health.
PMID: 31951763 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - January 18, 2020 Category: Geriatrics Authors: Yoldemir T Tags: Climacteric Source Type: research

Associations among menopausal status, menopausal symptoms, and depressive symptoms in midlife women in Hunan Province, China.
Conclusions: Independent of demographic variables, menopausal transition, postmenopause, and four menopausal symptoms (mood swing, depressive mood, palpitations, and urinary tract infection) increase the risk of depressive symptoms. PMID: 31951757 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - January 17, 2020 Category: Geriatrics Authors: Fu JX, Luo Y, Chen MZ, Zhou YH, Meng YT, Wang T, Qin S, Xu C Tags: Climacteric Source Type: research

Evaluation of CD4+CD25+FOXP3+ regulatory T cells and FOXP3 mRNA in premature ovarian insufficiency.
Conclusions: Our study suggested that POI may be associated with an abrogated function of circulating CD4+CD25+FOXP3+ Treg cells and a decreased level of FOXP3 gene expression. However, these results require further investigation. PMID: 31939315 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - January 15, 2020 Category: Geriatrics Authors: Xiong J, Tan R, Wang W, Wang H, Pu D, Wu J Tags: Climacteric Source Type: research

Association of oral estradiol dose/levels with coagulation measures in early/late postmenopausal women.
This study evaluated associations of estradiol (E2) dose and serum E2 levels with coagulation/anti-coagulation measures in early (
Source: Climacteric - January 15, 2020 Category: Geriatrics Authors: Sriprasert I, Hodis HN, Bernick B, Mirkin S, Mack WJ Tags: Climacteric Source Type: research

Spouses' perceptions of and attitudes toward female menopause: a mixed-methods systematic review.
Conclusion: Although there was little evidence, it seems that male spouses' perceptions of and attitudes toward female menopause are important factors affecting menopausal women's quality of life. PMID: 31933386 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - January 14, 2020 Category: Geriatrics Authors: Zhang X, Wang G, Wang H, Wang X, Ji T, Hou D, Wu J, Sun J, Zhu B Tags: Climacteric Source Type: research

Menopausal symptoms are associated with non-adherence to highly active antiretroviral therapy in human immunodeficiency virus-infected middle-aged women.
Conclusion: The severity of menopausal symptoms was associated with HAART non-adherence in HIV-infected middle-aged women. PMID: 31809600 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - December 6, 2019 Category: Geriatrics Authors: Cutimanco-Pacheco V, Arriola-Montenegro J, Mezones-Holguin E, Niño-Garcia R, Bonifacio-Morales N, Lucchetti-Rodríguez A, Ticona-Chávez E, Blümel JE, Pérez-López FR, Chedraui P Tags: Climacteric Source Type: research

Ringing the bell and then falling off a cliff … life after cancer.
Ringing the bell and then falling off a cliff … life after cancer. Climacteric. 2019 Dec;22(6):533-534 Authors: Bell RJ PMID: 31612747 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - October 16, 2019 Category: Geriatrics Authors: Bell RJ Tags: Climacteric Source Type: research

Will estradiol/progesterone capsules for oral use become the best choice for menopausal hormone therapy?
PMID: 31612748 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - October 16, 2019 Category: Geriatrics Authors: Mueck AO, Ruan X Tags: Climacteric Source Type: research

Correction.
Authors: PMID: 31612749 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - October 16, 2019 Category: Geriatrics Tags: Climacteric Source Type: research

Low bone mass is associated with carotid calcification plaque in Chinese postmenopausal women: the Chongqing osteoporosis study.
Conclusions: This study suggested that lower BMD and increased loss rate of BMD were associated with a higher risk of carotid calcification plaques in Chinese postmenopausal women. PMID: 31612731 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 15, 2019 Category: Geriatrics Authors: Liu D, Chen L, Dong S, Yang H, Li L, Liu J, Zhou H, Zhou R Tags: Climacteric Source Type: research

The maintenance effect of acupuncture on breast cancer-related menopause symptoms: a systematic review.
Conclusions: Acupuncture significantly alleviated menopause symptoms for at least 3 months, but not hot flushes. Breast cancer patients concerned about the adverse effects of hormone therapy could consider acupuncture as an alternative. Additional acupuncture at 3 months after the initial treatment course could be considered. A large-scale study may help to define the optimal guideline for this issue. PMID: 31612733 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 15, 2019 Category: Geriatrics Authors: Chien TJ, Liu CY, Fang CJ, Kuo CY Tags: Climacteric Source Type: research

Muscle health in Hispanic women. REDLINC VIII.
Conclusion: With aging there is a decrease in muscle strength and an increase in frailty. This entails a decrease in the quality of life. PMID: 31588809 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 7, 2019 Category: Geriatrics Authors: Blümel JE, Salinas C, Danckers L, Tserota K, Ojeda E, Vallejo MS, Arteaga E Tags: Climacteric Source Type: research

Obesity in midlife: lifestyle and dietary strategies.
Abstract As the rate of obesity increases globally, so does the incidence of other non-communicable diseases such as diabetes, cardiovascular disease, cancer, osteoporosis, osteoarthritis, and dementia, which have been referred to as 'adiposity-based chronic disease'. With timely lifestyle modification such as behavioral changes, implementation of a healthy diet, and proper physical activity, many of these diseases can be prevented. Weight gain is one of the major health concerns of midlife. Midlife body changes are the result of aging, menopause, and other influences unique to menopausal women which interfere wit...
Source: Climacteric - October 2, 2019 Category: Geriatrics Authors: Khandelwal S Tags: Climacteric Source Type: research

What is the position of testosterone in the care of women?
PMID: 31475871 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - September 3, 2019 Category: Geriatrics Authors: Davis SR Tags: Climacteric Source Type: research

Global Consensus Position Statement on the Use of Testosterone Therapy for Women.
PMID: 31474158 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 2, 2019 Category: Geriatrics Authors: Davis SR, Baber R, Panay N, Bitzer J, Cerdas Perez S, Islam RM, Kaunitz AM, Kingsberg SA, Lambrinoudaki I, Liu J, Parish SJ, Pinkerton J, Rymer J, Simon JA, Vignozzi L, Wierman ME Tags: Climacteric Source Type: research

A study protocol of vaginal laser therapy in gynecological cancer survivors.
Conclusion: Pelvic radiotherapy for GC increases the 5-year survival rate but with a negative impact on women's quality of life due to sexual dysfunction and radiation cystitis onset. With this study, CO2 laser therapy will be evaluated for the first time in GC survivors treated with radiotherapy. ClinicalTrials.gov registration number: NCT03714581. PMID: 31474161 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 2, 2019 Category: Geriatrics Authors: Athanasiou S, Pitsouni E, Grigoriadis T, Michailidis G, Tsiveleka A, Rodolakis A, Loutradis D Tags: Climacteric Source Type: research

Menopausal symptoms, menopausal stage and cognitive functioning in black urban African women.
Abstract Objective: Studies, conducted largely in North America and Europe, demonstrate that menopausal symptoms and menopausal stage influence cognitive function. Here, we evaluate these associations in a large cohort of sub-Saharan African women, a population where these associations are understudied. We hypothesized that premenopausal women would show better cognitive performance than women later in the transition, and that menopausal symptoms would be inversely related to cognition. Methods: This cross-sectional study included 702 black urban South African women between the ages of 40 and 60 years from the Stu...
Source: Climacteric - August 28, 2019 Category: Geriatrics Authors: Jaff NG, Rubin LH, Crowther NJ, Norris SA, Maki PM Tags: Climacteric Source Type: research

Screening sarcopenia through SARC-F in postmenopausal women: a single-center study from South America.
This study aimed to estimate the prevalence of postmenopausal women at high risk of sarcopenia and to compare their quality of life (QOL) with those at low risk using the SARC-F questionnaire. Methods: We performed a cross-sectional study of postmenopausal women who attended a menopause clinic in Colombia. The risk of sarcopenia was determined through the SARC-F questionnaire; a score ≥4 was considered high risk. The Menopause Rating Scale, the International Physical Activity Questionnaire, and the Short Physical Performance Battery (SPPB) tool were applied. Results: A total of 112 postmenopausal women with an average a...
Source: Climacteric - August 28, 2019 Category: Geriatrics Authors: Gómez-Tabares G, García W, Bedoya-Dorado E, Cantor E Tags: Climacteric Source Type: research

Managing menopausal symptoms after cancer.
Abstract The joint burden of cancer and menopause impacts millions of women globally. This review provides an approach to management of menopausal symptoms after cancer in all settings. This includes an overview of current evidence for both hormonal and non-hormonal treatments for vasomotor symptoms and vaginal dryness after cancer. Systemic menopausal hormone therapy provides symptom control and may be used after most cancers but should be avoided after estrogen receptor-positive breast cancer and after some other estrogen-dependent cancers. Non-hormonal therapies have been minimally studied in women after a canc...
Source: Climacteric - August 21, 2019 Category: Geriatrics Authors: Szabo RA, Marino JL, Hickey M Tags: Climacteric Source Type: research

Vulvovaginal atrophy in women after cancer.
Abstract The number of women surviving longer after a cancer diagnosis is increasing. This means that more awareness regarding their health is required. This review will focus on vulvovaginal atrophy (VVA)/genitourinary syndrome of menopause, one of the most distressing adverse iatrogenic effects of the menopause, secondary to cancer therapies. The cancer therapies themselves, such as radiotherapy, chemotherapy, and surgery, have a direct impact on the lower genital tract which interplays with the ensuing hypoestrogenic state of the menopause. Symptoms of VVA are still under-reported and undertreated as neither cl...
Source: Climacteric - August 14, 2019 Category: Geriatrics Authors: Cox P, Panay N Tags: Climacteric Source Type: research

Correction.
Authors: PMID: 31378091 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - August 5, 2019 Category: Geriatrics Tags: Climacteric Source Type: research

Cancer costs and gender: a snapshot of issues, trends, and opportunities to reduce inequities using Australia as an example.
Abstract As the cancer burden increases, so too does the cost, to health systems, economies, and individuals. There is increasing interest in productivity and out-of-pocket costs for individuals and their carers, but these remain poorly understood. The costs of cancer in women, often carers themselves, are less understood. This summary analysis explored data on the cancer burden in Australia (and health costs in comparable countries), including expenditure reports and literature on macroeconomic outcomes and out-of-pocket costs, to highlight the cost impacts of a cancer diagnosis in women, at a societal and an ind...
Source: Climacteric - August 5, 2019 Category: Geriatrics Authors: Feletto E, Grogan P, Vassallo A, Canfell K Tags: Climacteric Source Type: research

Assessing symptomatic vulvar, vaginal, and lower urinary tract atrophy.
The objective of this review is to provide an overview of existing and evolving methods of assessing symptomatic vulvar, vaginal, and lower urinary tract atrophy A systematic literature search was carried out on MEDLINE and Embase in order to identify studies on diagnostic instruments for vulvar, vaginal, and lower urinary tract atrophy, as well as new possibilities allowing for an improved diagnostic future. Measurement of the most bothersome symptoms, especially dyspareunia and vaginal dryness, is possibly the most useful parameter in clinical practice, even though it is a subjective measurement. Regarding objective resu...
Source: Climacteric - June 4, 2019 Category: Geriatrics Authors: Palacios S Tags: Climacteric Source Type: research