Screening for women at midlife: we need to remain vigilant.
PMID: 29714088 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - May 2, 2018 Category: Geriatrics Authors: Bell RJ Tags: Climacteric Source Type: research

History of a brief time: reflections of the first female President.
PMID: 29714089 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - May 2, 2018 Category: Geriatrics Authors: Ann Lumsden M Tags: Climacteric Source Type: research

Pelvic floor muscle function and EMG in nulliparous women of different ages: a cross-sectional study.
CONCLUSION: This study found no difference in PFM function and activity between nulliparous women in the five different age groups. Future long-term large prospective studies are required to confirm these findings. PMID: 29635954 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 11, 2018 Category: Geriatrics Authors: Bocardi DAS, Pereira-Baldon VS, Ferreira CHJ, Avila MA, Beleza ACS, Driusso P Tags: Climacteric Source Type: research

Evidence on the use of progesterone in menopausal hormone therapy.
Abstract A need exists for a regulatory agency-approved hormone therapy (HT) with naturally occurring hormones combining progesterone (P4) and estradiol (E2), since no single product contains both endogenous hormones. Many women choose HT with P4 and millions of women around the world are using unapproved, poorly regulated compounded HT. The use of natural P4 in HT results, for the most part, in favorable outcomes without deleterious effects, as shown in clinical studies of postmenopausal women. Importantly, P4 used in HT prevents endometrial hyperplasia from estrogens while helping relieve vasomotor symptoms and ...
Source: Climacteric - April 9, 2018 Category: Geriatrics Authors: Mirkin S Tags: Climacteric Source Type: research

An unusual hazard of menopause in the workplace: a case report.
We report the case of a 40-year-old woman with cold urticaria. Cold urticaria is a serious, potentially life-threatening condition. Our patient's symptoms were exacerbated when her postmenopausal work colleagues turned the air-conditioner temperature down to relieve their vasomotor symptoms. PMID: 29609500 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - April 3, 2018 Category: Geriatrics Authors: Stuckey BGA, Stuckey MS Tags: Climacteric Source Type: research

Postmenopausal endometriosis: drawing a clearer clinical picture.
Abstract This review aims to draw a clearer clinical picture of postmenopausal endometriosis. Based on limited literature, postmenopausal endometriosis emerges as an infrequent entity but with a clinical picture significantly unlike that of premenopausal endometriosis. In contrast to the premenopausal disease, postmenopausal endometriosis occurs in a state of ovarian estrogen deficiency, appears to have a greater predisposition to malignant change, may have a greater tendency to spread to extragonadal organs and develop into constrictive and/or obstructive lesions, and is preferably treated surgically. The need to...
Source: Climacteric - April 3, 2018 Category: Geriatrics Authors: Tan DA, Almaria MJG Tags: Climacteric Source Type: research

Bowel cancer screening for women at midlife.
Abstract In Australia one in 15 women will be diagnosed with colorectal cancer in their lifetime because of the high incidences of lifestyle risk factors. The risk could be reduced by taking aspirin. Evidence-based Clinical Practice Guidelines for the prevention, early detection and management of colorectal cancer produced by Cancer Council Australia and approved by the National Health and Medical Research Council recommended that 'population screening in Australia, directed at those at average risk of colorectal cancer and without relevant symptoms, is immunochemical fecal occult blood testing every 2 year...
Source: Climacteric - April 3, 2018 Category: Geriatrics Authors: Olver I Tags: Climacteric Source Type: research

Prediction of age at menopause in women with polycystic ovary syndrome: methodological issues.
PMID: 29493365 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - March 2, 2018 Category: Geriatrics Authors: Sabour S Tags: Climacteric Source Type: research

Authors' reply.
Minooee S, Ramezani Tehrani F, Rahmati M, Azizi F PMID: 29493366 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - March 2, 2018 Category: Geriatrics Authors: Authors' reply. Tags: Climacteric Source Type: research

Editor's comment.
PMID: 29493367 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - March 2, 2018 Category: Geriatrics Authors: Baber RJ Tags: Climacteric Source Type: research

The role of transvaginal ultrasound in screening for ovarian cancer.
Abstract Ovarian cancer is a low-prevalence postmenopausal cancer with a high mortality rate and is the fifth most lethal cancer in women. The most common serous subtype with TP53 mutations spreads rapidly throughout the peritoneal cavity (stage III/IV) when 5-year survival is 10%. If diagnosed while confined to the ovary (stage I), the survival rate exceeds 90%. This is the rationale for screening. Annual transvaginal ultrasound (TVU) scans used as a primary screening modality or as a second-line test following primary screening with serum CA125 (multimodal) have been investigated in several trials. Only two larg...
Source: Climacteric - March 1, 2018 Category: Geriatrics Authors: Campbell S, Gentry-Maharaj A Tags: Climacteric Source Type: research

Surgical challenges in the treatment of perimenopausal and postmenopausal endometriosis.
Abstract Endometriosis is classically defined as a chronic, recurrent and progressive disease. It is known to be estrogen-dependent, but can still be observed during the peri- and postmenopausal periods. Medical management of endometriosis is palliative symptomatic relief. Surgery when properly and timely performed for the right person may treat endometriosis. However, there is always a risk of possible major or minor surgical complications, as well as loss of some functions due to nerve damage. Management of endometriosis in the woman approaching the end of her reproductive life may require special attention both...
Source: Climacteric - March 1, 2018 Category: Geriatrics Authors: Ozyurek ES, Yoldemir T, Kalkan U Tags: Climacteric Source Type: research

Innovative approaches to cervical cancer screening in low- and middle-income countries.
Abstract The estimated cervical cancer burden is over ten-fold greater in low- and middle-income countries (LMICs) than in high-income countries. This health gap is thought to be primarily due to limited access to effective screening and treatment programs for cervical pre-cancer and cancer in such settings. The World Health Organization advocates a policy of 'screen and treat' approach to cervical screening in LMICs and subsequently visual inspection of the cervix with acetic acid (VIA) or Lugo's iodine (VILI), followed by ablative cervical cryotherapy if indicated, and this policy has been implemented in many hi...
Source: Climacteric - February 28, 2018 Category: Geriatrics Authors: Toliman PJ, Kaldor JM, Tabrizi SN, Vallely AJ Tags: Climacteric Source Type: research

Effects of oral contraceptives on ovulation induction in in vitro fertilization patients with premature ovarian insufficiency.
CONCLUSION: Oral contraception may be an effective method to induce ovulation for some patients with premature ovarian insufficiency. PMID: 29488818 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - February 28, 2018 Category: Geriatrics Authors: Chen M, Han H, Chuai Y, Hao M, Shu M, Shang W Tags: Climacteric Source Type: research

Role of breast density measurement in screening for breast cancer.
Abstract Mammographic breast density is an established risk factor for breast cancer and significantly reduces the sensitivity of mammography, yet its use within breast cancer screening programs in Australia is limited. We provide a contemporary snapshot of the role of breast density measurement in screening for breast cancer and review the recent evidence for an increasing role of breast density measurement as: a predictor of breast cancer risk, a predictor of 'masking', and a biomarker to monitor effectiveness of intervention strategies for primary prevention or improved breast cancer outcomes. PMID: 294470...
Source: Climacteric - February 15, 2018 Category: Geriatrics Authors: McLean KE, Stone J Tags: Climacteric Source Type: research

Should women be screened for osteoporosis at midlife?
Abstract Osteoporosis and associated fractures are common in women after midlife and will increase as the population ages. Osteoporosis-related fractures cause a significant increase in morbidity and mortality. Osteoporosis decreases the quality of life and productivity of many older women, with an increasing burden on health-care resources. Future risk of fracture can be managed by evidence-based interventions. It is thus appropriate to estimate the future risk of fracture in all women at the age of 50 years or at menopause, whichever occurs first. This can be achieved in a non-invasive fashion by targeted...
Source: Climacteric - February 15, 2018 Category: Geriatrics Authors: de Villiers TJ Tags: Climacteric Source Type: research

Long-term effects of vaginal erbium laser in the treatment of genitourinary syndrome of menopause.
Abstract OBJECTIVES: To evaluate the long-term efficacy of a second generation of vaginal laser treatment, the vaginal erbium laser, as a non-ablative photothermal therapy for the management of genitourinary syndrome of menopause. METHODS: The study was performed using an erbium laser crystal yttrium-aluminum-garnet (XS Fotona Smooth™, Fotona, Ljubljana, Slovenia) with a wavelength of 2940 nm. Postmenopausal women (n = 205) were treated with three laser applications at 30-day intervals. Symptoms were assessed before and after treatment throughout 24 months, using the subjecti...
Source: Climacteric - February 13, 2018 Category: Geriatrics Authors: Gambacciani M, Levancini M, Russo E, Vacca L, Simoncini T, Cervigni M Tags: Climacteric Source Type: research

Romosozumab treatment in postmenopausal women with osteoporosis: a meta-analysis of randomized controlled trials.
Abstract AIM: To conduct a systematic review and meta-analysis of randomized controlled trials (RCTs) to evaluate the safety and efficacy of romosozumab in the treatment of postmenopausal osteoporosis. METHOD: A comprehensive literature review was performed of PubMed, EMBASE, Cochrane Controlled Trials Registry, and Web of Science for RCTs. Outcome measures were changes in lumbar spine, total hip and femoral neck bone mineral density (BMD), incidence of fractures and adverse events. Six trials were finally included. RESULTS: Romosozumab resulted in a significantly lower risk of new vertebral fracture (re...
Source: Climacteric - February 9, 2018 Category: Geriatrics Authors: Liu Y, Cao Y, Zhang S, Zhang W, Zhang B, Tang Q, Li Z, Wu J Tags: Climacteric Source Type: research

Traditional Chinese medicine: perspectives on and treatment of menopausal symptoms.
PMID: 29419312 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - February 8, 2018 Category: Geriatrics Authors: Yu Q Tags: Climacteric Source Type: research

Decision-making about mammographic screening: pursuing informed choice.
Abstract For decades, persuasive techniques have been used to communicate to women about breast cancer screening with the aim of maximizing screening uptake. However, more recently this has shifted to an approach which recognizes that it is important for women to be aware of harms, such as overdiagnosis, as well as benefits of breast screening. There is a lack of consensus in the literature around whether benefits clearly outweigh harms for population-based breast cancer screening. In light of this, the gold standard for communication about breast cancer screening is now to try and support informed decision-making...
Source: Climacteric - February 8, 2018 Category: Geriatrics Authors: Hersch J, Jansen J, McCaffery K Tags: Climacteric Source Type: research

Genitourinary syndrome of menopause. Prevalence and quality of life in Spanish postmenopausal women. The GENISSE study.
CONCLUSIONS: The GSM is very prevalent in Spanish postmenopausal women, affecting up to 70% of those consulting the gynecologist. Despite the high prevalence of symptoms and signs and its impact on the women's well-being, GSM remains underdiagnosed and undertreated. Given its relationship with urogynecological conditions, it seems necessary to provide an adequate evaluation of postmenopausal women for identifying potential co-morbidities and providing most adequate treatments. An adequate management of GSM will contribute to an improvement in the quality of life of these women. PMID: 29411644 [PubMed - as supplied by ...
Source: Climacteric - February 7, 2018 Category: Geriatrics Authors: Moral E, Delgado JL, Carmona F, Caballero B, Guillán C, González PM, Suárez-Almarza J, Velasco-Ortega S, Nieto C, as the writing group of the GENISSE study Tags: Climacteric Source Type: research

Depressive symptoms affect outcomes of pessary use in postmenopausal women with uterine prolapse.
This study aimed to investigate the impact of depressive symptoms on successful pessary treatment for postmenopausal women with symptomatic pelvic organ prolapse (POP). METHODS: We performed a prospective study involving postmenopausal women with POP who visited our clinic seeking pessary treatment. Demographic information and medical histories were collected. The participants completed the following questionnaires at baseline and after 3 months of successful pessary use: (1) the Pelvic Floor Impact Questionnaire-7 (PFIQ-7); (2) the Pelvic Floor Distress Inventory (PFDI-20); and (3) the Patient Health Questionn...
Source: Climacteric - February 3, 2018 Category: Geriatrics Authors: Ai FF, Zhu L, Mao M, Zhang Y, Kang J Tags: Climacteric Source Type: research

Association of body composition with menopausal symptoms in (peri-)menopausal women.
Abstract OBJECTIVE: To explore the correlation of body composition with the severity of menopausal symptoms, as well as each classic menopausal symptom. METHODS: A total of 758 (peri-)menopausal women were recruited (aged from 40 to 67 years) from the Menopause Clinic in the Shanghai Sixth People's Hospital. Different regions of fat mass, lean mass and fat-free mass were measured by bioelectrical impedance analysis, while menopausal symptoms were evaluated by valid modified Kupperman's index (KMI) in the Chinese version. RESULTS: After adjusting for potential confounders, logistic regression revea...
Source: Climacteric - February 2, 2018 Category: Geriatrics Authors: Zhou Y, Zheng Y, Li C, Hu J, Zhou Y, Geng L, Tao M Tags: Climacteric Source Type: research

Vasomotor symptoms: natural history, physiology, and links with cardiovascular health.
Abstract Vasomotor symptoms (VMS), or hot flushes and night sweats, are the classic symptom of menopause. Recent years have brought key advances in the knowledge about VMS. VMS last longer than previously thought, on average 7-10 years for frequent or moderate to severe VMS. Although VMS have long been understood to be important to women's quality of life, research has also linked VMS to indicators of cardiovascular disease (CVD) risk, such as an adverse CVD risk factor profile, greater subclinical CVD and, in emerging work, CVD events. Relations between VMS and CVD are not typically accounted for by CVD ri...
Source: Climacteric - February 2, 2018 Category: Geriatrics Authors: Thurston RC Tags: Climacteric Source Type: research

Obesity during female midlife.
PMID: 29291324 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - January 3, 2018 Category: Geriatrics Authors: Chedraui P Tags: Climacteric Source Type: research

Correction to: Rosano et al., Cardiovascular disease in women, is it different to men? The role of sex hormones.
Authors: PMID: 29267128 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - December 21, 2017 Category: Geriatrics Tags: Climacteric Source Type: research

Combined effects of ovariectomy and streptozotocin-induced diabetes in the articular cartilage of rats.
cio-Silva R Abstract AIM: To evaluate the combined effects of streptozotocin-induced diabetes (Di) and ovariectomy in the articular cartilage of rats. METHODS: Forty adult female Wistar rats were ovariectomized (OVX) or sham-operated. After recovery from surgery, the animals were assigned randomly into four groups: OVX control (OVX-C); OVX treated with 10 µg/kg/day of 17β-estradiol (OVX-E); sham-operated subjected to Di (Sham-Di); and OVX subjected to Di (OVX-Di). After 60 days of treatment, the animals were euthanized and the distal femurs with articular cartilage were processed for paraffin-embed...
Source: Climacteric - December 12, 2017 Category: Geriatrics Authors: Saeki Fernandes A, Fonseca CCN, Rodrigues da Silva Sasso G, Carvalho Cezar L, Aparecida Dos Santos M, Simões MJ, Simões RS, Florencio-Silva R Tags: Climacteric Source Type: research

Clinicopathological and prognostic significance of platelet count in patients with ovarian cancer.
CONCLUSION: This meta-analysis revealed that an elevated platelet count pretreatment denotes a predictive factor of poor prognosis and unfavorable clinicopathological parameters for ovarian cancer patients. PMID: 29231068 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - December 12, 2017 Category: Geriatrics Authors: Zhou Q, Huang F, He Z, Zuo MZ Tags: Climacteric Source Type: research

The futile case of the aging ovary: is it mission impossible? A focused review.
Abstract Despite immense and impressive progress in the field of reproductive medicine, little has been achieved in terms of replenishing aged ovaries and improving their reproductive outcome. Age causes irreversible damage to human eggs in terms of quantity as well as quality. Nature probably designed women to reproduce best in their twenties and thirties. However, due to social, personal, career, educational and financial pressures, women delay pregnancies until their late thirties, by which time the chance of becoming pregnant is compromised by low fecundity rates and an increased risk of miscarriage. Age, unfo...
Source: Climacteric - December 8, 2017 Category: Geriatrics Authors: Rasool S, Shah D Tags: Climacteric Source Type: research

Predictors of malignancy in endometrial polyps: study of 421 women with postmenopausal bleeding.
CONCLUSION: The prevalence of hyperplasia and cancer in benign-looking polyps is high. The independent predictors are body mass index and endometrial thickness. Removal of polyps may be warranted until hysteroscopic morphological criteria that can reliably predict the outcome are established in future research. PMID: 29219004 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - December 8, 2017 Category: Geriatrics Authors: Ghoubara A, Sundar S, Ewies AAA Tags: Climacteric Source Type: research

Efficacy and safety evaluation of Cimicifuga foetida extract in menopausal women.
CONCLUSIONS: C. foetida extract is safe and effective for the treatment of menopausal symptoms in postmenopausal women. PMID: 29198157 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - December 4, 2017 Category: Geriatrics Authors: Gao L, Zheng T, Xue W, Wang Y, Deng Y, Zuo H, Sun A Tags: Climacteric Source Type: research

Teaching the teachers.
PMID: 29105537 [PubMed - in process] (Source: Climacteric)
Source: Climacteric - November 8, 2017 Category: Geriatrics Authors: Baber R Tags: Climacteric Source Type: research

Prediction of age at menopause in women with polycystic ovary syndrome.
Abstract OBJECTIVE: Considering the role of anti-Müllerian hormone (AMH) in female fertility and its high levels in women with polycystic ovary syndrome (PCOS), the longer reproductive span of these women is in doubt. In the present study, we aimed to improve earlier predictions using a non-linear model to substantiate the question as to whether PCOS women reach menopause later. METHODS: In total, 1162 women aged 20-50 years, comprising 378 PCOS cases and 784 eumenorrheic non-hirsute women, met the eligibility criteria. A scatterplot matrix was drawn to detect the association between age and AMH; this as...
Source: Climacteric - November 6, 2017 Category: Geriatrics Authors: Minooee S, Ramezani Tehrani F, Rahmati M, Mansournia MA, Azizi F Tags: Climacteric Source Type: research

Menopause, lung function and obstructive lung disease outcomes: a systematic review.
CONCLUSIONS: As the global burden associated with respiratory conditions continues to rise, the need to understand the associations between menopause and respiratory health is essential to identify potentially modifiable risk factors for respiratory disease in adult women. More studies are needed to clarify the impact of menopause on obstructive lung disease. PMID: 29106307 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - November 6, 2017 Category: Geriatrics Authors: Campbell B, Davis SR, Abramson MJ, Mishra G, Handelsman DJ, Perret JL, Dharmage SC Tags: Climacteric Source Type: research

Screening for general anxiety disorders in postmenopausal women with symptomatic pelvic organ prolapse.
This study aimed to investigate the prevalence of general anxiety disorder (GAD) among postmenopausal women with symptomatic pelvic organ prolapse (POP) and to identify its associated factors. METHODS: A cross-sectional study was conducted among postmenopausal women with symptomatic POP. Sociodemographic data and medical histories were obtained. Participants completed the POP Quantification (POP-Q), the Pelvic Floor Impact Questionnaire-7 (PFIQ-7), and the Pelvic Floor Distress Inventory (PFDI-20) measures. Measures of GAD were obtained using the Generalized Anxiety Disorder-7 (GAD-7). The data were analyzed using ind...
Source: Climacteric - November 2, 2017 Category: Geriatrics Authors: Ai F, Deng M, Mao M, Xu T, Zhu L Tags: Climacteric Source Type: research

Metabolic syndrome in menopause and associated factors: a meta-analysis.
CONCLUSIONS: Menopause nearly adversely affects all components of MetS, and surgical menopause may lead to a higher incidence of MetS compared to natural menopause. HT with various preparations may have different effects on MetS components. These results may clarify the management of menopause-related MetS in clinical practice. PMID: 29064321 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 24, 2017 Category: Geriatrics Authors: Pu D, Tan R, Yu Q, Wu J Tags: Climacteric Source Type: research

No increased death toll for long-term menopausal hormone therapy.
Abstract It took many years since the initial publication of data from the Women's Health Initiative (WHI) study until further analyses and additional accumulated clinical information allowed realization of the full scope of its results. At first, the focus was on morbidity, mainly the slightly higher incidence of cardiovascular events and breast cancer cases among postmenopausal hormone users. Then, the age factor became evident, and the good safety profile of hormone therapy in healthy women initiating treatment near menopause and using it for up to 10 years eased the previous concerns. Now, 15 years after the f...
Source: Climacteric - October 23, 2017 Category: Geriatrics Authors: Pines A Tags: Climacteric Source Type: research

Neurokinin 3 receptor antagonism - the magic bullet for hot flushes?
Abstract Hot flushes affect 70% of menopausal women and are reported as being the most bothersome symptom by the majority. Hormone replacement therapy and other currently available alternative therapies are not without side-effects and/or have variable efficacy, and so an effective novel therapy could be practice-changing. Over the last 20 years, numerous studies in animal and human models have implicated neurokinin B, a hypothalamic neuropeptide, together with its receptor (NK3R) in the etiology of menopausal hot flushes. Most recently, a randomized, placebo-controlled trial of an NK3R antagonist in symptomatic m...
Source: Climacteric - October 17, 2017 Category: Geriatrics Authors: Prague JK, Dhillo WS Tags: Climacteric Source Type: research

Effects of omega-3 fatty acids on bone turnover markers in postmenopausal women: systematic review and meta-analysis.
CONCLUSION: Omega-3 fatty acids reduced postmenopausal women's serum osteocalcin. Further well-designed studies are needed to verify the effects of omega-3 fatty acids on bone mass density and other bone turnover markers in postmenopausal women. CLINICAL TRIAL REGISTRATION NUMBER: CRD42016053219 ( https://www.crd.york.ac.uk/PROSPERO/ ). PMID: 29034731 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 16, 2017 Category: Geriatrics Authors: Shen D, Zhang X, Li Z, Bai H, Chen L Tags: Climacteric Source Type: research

FSH to estradiol ratio can be used as screening method for mild cognitive impairment in postmenopausal women.
CONCLUSIONS: The ratio of FSH to estradiol (>1.94) can be used as a screening method for the occurrence of MCI in postmenopausal women. PMID: 28980489 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - October 5, 2017 Category: Geriatrics Authors: Hestiantoro A, Wiwie M, Shadrina A, Ibrahim N, Purba JS Tags: Climacteric Source Type: research

The association of hyperuricemia and metabolic syndrome in Thai postmenopausal women.
Abstract OBJECTIVE: The purpose of this study was to evaluate the association of hyperuricemia and metabolic syndrome (MS) in Thai postmenopausal women. METHODS: A total of 740 consecutive Thai postmenopausal women were reviewed who were not receiving uric acid or lipid-lowering agents at the Menopause Clinic, Faculty of Medicine Siriraj Hospital, Bangkok, from January 2004 to January 2016. Hyperuricemia was defined as serum uric acid level>5.7 mg/dl. The revised National Cholesterol Education Program (rNCEP) 2004 criteria were used for diagnosis of MS. The association of hyperuricemia and MS was ev...
Source: Climacteric - September 22, 2017 Category: Geriatrics Authors: Techatraisak K, Kongkaew T Tags: Climacteric Source Type: research

17 β-Estradiol induces proliferation of endometrial NK cells (CD56+) in postmenopausal women.
CONCLUSION: 17β-Estradiol induced the proliferation of endometrial uterine natural killer cells (CD56+) in postmenopausal women. PMID: 28933961 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 21, 2017 Category: Geriatrics Authors: Sho T, Hachisuga T, Koi C, Kurita T, Kagami S, Kawagoe T, Matsuura Y, Yoshimura K, Hisaoka M Tags: Climacteric Source Type: research

Influence of menopausal symptoms on perceived work ability among women in a Nigerian University.
This study investigated the menopausal symptoms experienced by women of menopausal age in Ekiti State, Nigeria and the influence on their perceived work ability. METHOD: A descriptive cross-sectional research design was employed and the study was conducted among 200 working-class women aged 45 years and above who had experienced at least 12 continuous months of amenorrhea in Ekiti State University, Ado Ekiti. A semi-structured questionnaire adapted from the Greene Climacteric Scale and the work ability index was used to assess menopausal symptoms and work ability, respectively. RESULT: The prevalence of menopausa...
Source: Climacteric - September 21, 2017 Category: Geriatrics Authors: Olajubu AO, Olowokere AE, Amujo DO, Olajubu TO Tags: Climacteric Source Type: research

The influence of unilateral oophorectomy on the age of menopause.
CONCLUSIONS: Premenopausal unilateral oophorectomy significantly reduces the age of menopause by 1.8 years. Younger age at UO leads to significantly younger age at menopause. PMID: 28933974 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 21, 2017 Category: Geriatrics Authors: Rosendahl M, Simonsen MK, Kjer JJ Tags: Climacteric Source Type: research

Foot problems in older women.
Abstract Between 20 and 45% of women aged over 65 years of age will develop one or more foot problems, which, although not specific to older women, are more common in that age group than in younger women. These include structural defects of the toes including hallux valgus, hammer, mallet or claw toes, skin disorders, fungal infection of the toes and toe nails, thickened toe nails, ulcers, fissures or cracks between the toes, corns and calluses, flat or high-arched feet. Foot pain is common and may be associated with other co-morbid diseases of the foot. Inappropriate footwear has an unfortunate role in the etiolo...
Source: Climacteric - September 21, 2017 Category: Geriatrics Authors: Guidozzi F Tags: Climacteric Source Type: research

Nordic walking increases circulating VEGF more than traditional walking training in postmenopause.
Abstract OBJECTIVES: Nordic walking (NW) is widely practiced by postmenopausal women. Its effects are peculiar owing to the involvement of more muscle groups than in traditional walking training (WT). Since mechanical load promotes secretion of vascular endothelial growth factor (VEGF) from both skeletal muscle and muscle endothelium, the aim of the study was to compare the effect of NW and WT on VEGF levels. METHOD: Thirty postmenopausal women were randomly assigned to NW or WT. Both groups trained 40-50 min/day, three times per week, at a mean intensity of 12 on a 15-category scale of the ratings of ...
Source: Climacteric - September 17, 2017 Category: Geriatrics Authors: Izzicupo P, D'Amico MA, Di Blasio A, Napolitano G, Di Baldassarre A, Ghinassi B Tags: Climacteric Source Type: research

Native tissue repair versus mesh repair in pelvic organ prolapse surgery.
Abstract In pelvic organ prolapse, the anatomical defects develop at the anterior (anterior vaginal wall), the posterior (posterior vaginal wall) and the apical (the uterus/cervix or the apex of the vagina, vaginal vault or cuff scar after hysterectomy) compartments. These defects occur in more than one compartment. Treatment of pelvic organ prolapse is commonly surgical, aiming to restore the anatomy of structures supporting the pelvic organs. The surgical repair techniques are classified as 'native tissue repair (NTR)' when only pelvic organ support tissues are used and 'augmented repair (AR)' when some other ma...
Source: Climacteric - September 5, 2017 Category: Geriatrics Authors: Kalkan U, Yoldemir T, Ozyurek ES, Daniilidis A Tags: Climacteric Source Type: research

Effects of soy isoflavones on the concentration of hyaluronic acid in the vagina of type 1 diabetic rats.
otilde;es M Abstract OBJECTIVE: To assess the effects of isoflavones and 17β-estradiol on the vaginal epithelium extracellular matrix and hyaluronic acid (HA) in the diabetic rat model. METHODS: Sixty adult, virgin, female rats underwent ovariectomy, then randomization into six groups of ten animals each: GI, sham ovariectomized control animals; GII, sham ovariectomized control diabetic animals; GIII, control ovariectomized rats receiving propylene glycol vehicle; GIV, control ovariectomized diabetic animals receiving propylene glycol vehicle; GV, diabetic ovariectomized animals treated with soy isoflavo...
Source: Climacteric - September 2, 2017 Category: Geriatrics Authors: F Carbonel AA, Azevedo Lima PD, Lim JJ, Teixeira Borges F, Rodrigues da Silva Sasso G, Portugal Fuchs LF, S Simões R, Chada Baracat E, Soares JM, J Simões M Tags: Climacteric Source Type: research

Turning the spotlight on lasers.
PMID: 28862053 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 1, 2017 Category: Geriatrics Authors: Hillard TC Tags: Climacteric Source Type: research

Turner syndrome - growing pressure for more multidisciplinary clinics for adults and earlier diagnosis in children.
PMID: 28862878 [PubMed - as supplied by publisher] (Source: Climacteric)
Source: Climacteric - September 1, 2017 Category: Geriatrics Authors: Conway GS Tags: Climacteric Source Type: research