Impact of vaginal estriol on serum hormone levels: a systematic review
Climacteric. 2024 Jan 2:1-17. doi: 10.1080/13697137.2023.2287624. Online ahead of print.ABSTRACTThe genitourinary syndrome of menopause (GSM) affects up to 84% of postmenopausal women and may significantly reduce the quality of life in some. For symptom relief, there are several non-hormonal and hormonal vaginal products available. In Europe, vaginal estriol (E3) is the most frequently chosen estrogen for GSM treatment. The aim of this systematic review was to assess the impact of vaginal E3 on serum sex hormone levels, an outcome that has been previously used to assess safety in similar products. In our review, we did not...
Source: Climacteric - January 2, 2024 Category: Geriatrics Authors: A Kolokythas C Betschart D Wunder H Janka P Stute Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research
Premature ovarian insufficiency and autoimmune profiles: a prospective case-control study
CONCLUSION: A high prevalence of autoimmunity in POI women compared to a healthy young collective could be demonstrated. Thyroid antibodies were significantly increased in POI women. Our data highlight the increased risk for autoimmune diseases, especially for thyroid disorders.PMID:38108204 | DOI:10.1080/13697137.2023.2287631 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: K Beitl J Ott K Rosta I Holzer P Foessleitner J Steininger N Panay Source Type: research
Estrogen as a guardian of auditory health: Tsp1-CD47 axis regulation and noise-induced hearing loss
CONCLUSIONS: OVX rats were more susceptible to NIHL, and the protective effect of estrogen was achieved through regulation of the Tsp1-CD47 axis. This study presents a novel mechanism through which estrogen regulates NIHL and offers a potential intervention strategy for the clinical treatment of NIHL.PMID:38108225 | DOI:10.1080/13697137.2023.2287632 (Source: Climacteric)
Source: Climacteric - December 18, 2023 Category: Geriatrics Authors: X Wang H Zheng B Yang M Zu Z Wang J Zhang F Zheng M Yang M C F Tong L Zhao W Bai Source Type: research