Ischemia but no obstructive coronary artery disease: more than meets the eye
Climacteric. 2024 Feb;27(1):22-31. doi: 10.1080/13697137.2023.2281933. Epub 2024 Jan 15.ABSTRACTSymptomatic women with angina are more likely to have ischemia with no obstructive coronary arteries (INOCA) compared to men. In both men and women, the finding of INOCA is not benign and is associated with adverse cardiovascular events, including myocardial infarction, heart failure and angina hospitalizations. Women with INOCA have more angina and a lower quality of life compared to men, but they are often falsely reassured because of a lack of obstructive coronary artery disease (CAD) and a perception of low risk. Coronary mi...
Source: Climacteric - January 15, 2024 Category: Geriatrics Authors: N Patel N Greene N Guynn A Sharma O Toleva P K Mehta Source Type: research

Progesterone and not estrogens or androgens causes breast cancer
Climacteric. 2024 Jan 10:1-6. doi: 10.1080/13697137.2023.2292073. Online ahead of print.NO ABSTRACTPMID:38197401 | DOI:10.1080/13697137.2023.2292073 (Source: Climacteric)
Source: Climacteric - January 10, 2024 Category: Geriatrics Authors: H J T Coelingh Bennink F Z Stanczyk Source Type: research

Primary prevention of cardiovascular disease in women
Climacteric. 2024 Feb;27(1):104-112. doi: 10.1080/13697137.2023.2282685. Epub 2024 Jan 15.ABSTRACTIschemic heart disease is the primary cause of cardiovascular disease (CVD) mortality in both men and women. Strategies targeting traditional modifiable risk factors are essential - including hypertension, smoking, dyslipidemia and diabetes mellitus - particularly for atherosclerosis, but additionally for stroke, heart failure and some arrhythmias. However, challenges related to education, screening and equitable access to effective preventative therapies persist, and are particularly problematic for women around the globe and...
Source: Climacteric - January 10, 2024 Category: Geriatrics Authors: M P Gray B Vogel R Mehran J A Leopold G A Figtree Source Type: research

Pregnancy-associated risk factors for future cardiovascular disease - early prevention strategies warranted
Climacteric. 2024 Feb;27(1):41-46. doi: 10.1080/13697137.2023.2287628. Epub 2024 Jan 15.ABSTRACTWe summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for ex...
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: T S Mikkola O Ylikorkala Source Type: research

Closing the gap: cardiovascular disease in women
This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology.PMID:38174697 | DOI:10.1080/13697137.2023.2281935 (Source: Climacteric)
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: M Nathani B Vogel R Mehran Source Type: research

Pregnancy-associated risk factors for future cardiovascular disease - early prevention strategies warranted
Climacteric. 2024 Jan 4:1-6. doi: 10.1080/13697137.2023.2287628. Online ahead of print.ABSTRACTWe summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for exa...
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: T S Mikkola O Ylikorkala Source Type: research

Closing the gap: cardiovascular disease in women
This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology.PMID:38174697 | DOI:10.1080/13697137.2023.2281935 (Source: Climacteric)
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: M Nathani B Vogel R Mehran Source Type: research

Pregnancy-associated risk factors for future cardiovascular disease - early prevention strategies warranted
Climacteric. 2024 Jan 4:1-6. doi: 10.1080/13697137.2023.2287628. Online ahead of print.ABSTRACTWe summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for exa...
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: T S Mikkola O Ylikorkala Source Type: research

Closing the gap: cardiovascular disease in women
This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology.PMID:38174697 | DOI:10.1080/13697137.2023.2281935 (Source: Climacteric)
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: M Nathani B Vogel R Mehran Source Type: research

Pregnancy-associated risk factors for future cardiovascular disease - early prevention strategies warranted
Climacteric. 2024 Jan 4:1-6. doi: 10.1080/13697137.2023.2287628. Online ahead of print.ABSTRACTWe summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for exa...
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: T S Mikkola O Ylikorkala Source Type: research

Closing the gap: cardiovascular disease in women
This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology.PMID:38174697 | DOI:10.1080/13697137.2023.2281935 (Source: Climacteric)
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: M Nathani B Vogel R Mehran Source Type: research

Pregnancy-associated risk factors for future cardiovascular disease - early prevention strategies warranted
Climacteric. 2024 Jan 4:1-6. doi: 10.1080/13697137.2023.2287628. Online ahead of print.ABSTRACTWe summarize convincing evidence that future cardiovascular disease (CVD) risk increases one-fold to four-fold for women with a history of pregnancy complicated by hypertensive disorders, gestational diabetes, fetal growth restriction, placental abruption and preterm birth. A concomitant occurrence of two or more complications in the same pregnancy further potentiates the risk. These women should be informed of their future CVD risks during the postpartum check-up taking place after delivery, and also, if needed, treated, for exa...
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: T S Mikkola O Ylikorkala Source Type: research

Closing the gap: cardiovascular disease in women
This article highlights important aspects of the Lancet Commission report and expands on the evidence and proposed strategies for reducing the global burden of CVD in women. Furthermore, the article explores the benefits of cross-specialty collaborations for the treatment and prevention of CVD in women and discusses the impact of gender-related disparities in academic cardiology.PMID:38174697 | DOI:10.1080/13697137.2023.2281935 (Source: Climacteric)
Source: Climacteric - January 4, 2024 Category: Geriatrics Authors: M Nathani B Vogel R Mehran Source Type: research

Impact of vaginal estriol on serum hormone levels: a systematic review
Climacteric. 2024 Jan 2:1-17. doi: 10.1080/13697137.2023.2287624. Online ahead of print.ABSTRACTThe genitourinary syndrome of menopause (GSM) affects up to 84% of postmenopausal women and may significantly reduce the quality of life in some. For symptom relief, there are several non-hormonal and hormonal vaginal products available. In Europe, vaginal estriol (E3) is the most frequently chosen estrogen for GSM treatment. The aim of this systematic review was to assess the impact of vaginal E3 on serum sex hormone levels, an outcome that has been previously used to assess safety in similar products. In our review, we did not...
Source: Climacteric - January 2, 2024 Category: Geriatrics Authors: A Kolokythas C Betschart D Wunder H Janka P Stute Source Type: research

Impact of vaginal estriol on serum hormone levels: a systematic review
Climacteric. 2024 Jan 2:1-17. doi: 10.1080/13697137.2023.2287624. Online ahead of print.ABSTRACTThe genitourinary syndrome of menopause (GSM) affects up to 84% of postmenopausal women and may significantly reduce the quality of life in some. For symptom relief, there are several non-hormonal and hormonal vaginal products available. In Europe, vaginal estriol (E3) is the most frequently chosen estrogen for GSM treatment. The aim of this systematic review was to assess the impact of vaginal E3 on serum sex hormone levels, an outcome that has been previously used to assess safety in similar products. In our review, we did not...
Source: Climacteric - January 2, 2024 Category: Geriatrics Authors: A Kolokythas C Betschart D Wunder H Janka P Stute Source Type: research