Reproductive milestones across the lifespan and cardiovascular disease risk in women
Climacteric. 2023 Sep 28:1-11. doi: 10.1080/13697137.2023.2259793. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is the leading cause of death for women across the developed and developing world. Beyond traditional cardiovascular risk factors, a number of reproductive milestones have been recognized. The goal of this White Paper, issued by the International Menopause Society in conjunction with World Menopause Day 2023, is to highlight female reproductive milestones in terms of potential cardiovascular risk and to review recommendations for minimizing that risk. The primary milestones discussed relate to menst...
Source: Climacteric - September 28, 2023 Category: Geriatrics Authors: C A Stuenkel Source Type: research

A disease of her own? Unique features of heart failure in women
Climacteric. 2023 Sep 28:1-9. doi: 10.1080/13697137.2023.2256673. Online ahead of print.ABSTRACTHeart failure (HF) is a significant and growing public health challenge for women. Compared with men, women tend to develop HF later in life and are more likely to experience HF with preserved ejection fraction. There are also significant sex differences in outcomes, with women reporting lower quality of life but overall better survival versus men. In this review, we summarize sex differences in traditional HF risk factors, such as hypertension, diabetes, obesity and coronary artery disease, as well as female-specific HF risk fa...
Source: Climacteric - September 28, 2023 Category: Geriatrics Authors: W A Spacht E S Lau Source Type: research

Reproductive milestones across the lifespan and cardiovascular disease risk in women
Climacteric. 2023 Sep 28:1-11. doi: 10.1080/13697137.2023.2259793. Online ahead of print.ABSTRACTCardiovascular disease (CVD) is the leading cause of death for women across the developed and developing world. Beyond traditional cardiovascular risk factors, a number of reproductive milestones have been recognized. The goal of this White Paper, issued by the International Menopause Society in conjunction with World Menopause Day 2023, is to highlight female reproductive milestones in terms of potential cardiovascular risk and to review recommendations for minimizing that risk. The primary milestones discussed relate to menst...
Source: Climacteric - September 28, 2023 Category: Geriatrics Authors: C A Stuenkel Source Type: research

A disease of her own? Unique features of heart failure in women
Climacteric. 2023 Sep 28:1-9. doi: 10.1080/13697137.2023.2256673. Online ahead of print.ABSTRACTHeart failure (HF) is a significant and growing public health challenge for women. Compared with men, women tend to develop HF later in life and are more likely to experience HF with preserved ejection fraction. There are also significant sex differences in outcomes, with women reporting lower quality of life but overall better survival versus men. In this review, we summarize sex differences in traditional HF risk factors, such as hypertension, diabetes, obesity and coronary artery disease, as well as female-specific HF risk fa...
Source: Climacteric - September 28, 2023 Category: Geriatrics Authors: W A Spacht E S Lau Source Type: research

Subjective cognitive changes following premenopausal risk-reducing bilateral salpingo-oophorectomy
CONCLUSION: Findings from this study suggest that women experience subjective cognitive changes within 24 months post BSO. This period could be a vulnerable time for women's cognitive health. While these findings need to be confirmed by a large prospective study, our research indicates that psychoeducation and awareness will be helpful in managing cognitive symptoms after surgical menopause.PMID:37751773 | DOI:10.1080/13697137.2023.2256659 (Source: Climacteric)
Source: Climacteric - September 26, 2023 Category: Geriatrics Authors: A Ramachandra E H X Thomas A J Vincent M Hickey N Warren J Kulkarni L E Forrest J Bojadzieva A Campbell C Gurvich Source Type: research

Global view of vasomotor symptoms and sleep disturbance in menopause: a systematic review
Climacteric. 2023 Sep 26:1-13. doi: 10.1080/13697137.2023.2256658. Online ahead of print.ABSTRACTStudies have shown racial/ethnic differences in the prevalence of vasomotor symptoms (VMS), sleep disturbance and VMS treatment in menopause. To assess the reproducibility of these differences, we systematically reviewed observational studies, published in 2000-2021, reporting the prevalence/incidence of VMS, sleep disturbance or treatment use in menopausal women stratified by race/ethnicity. We screened 3799 records from PubMed and Embase and included 27 papers (19 studies). No incidence data were found. Prevalence data varied...
Source: Climacteric - September 26, 2023 Category: Geriatrics Authors: S A Kingsberg R Schulze-Rath C Mulligan C Moeller C Caetano J Bitzer Source Type: research

Subjective cognitive changes following premenopausal risk-reducing bilateral salpingo-oophorectomy
CONCLUSION: Findings from this study suggest that women experience subjective cognitive changes within 24 months post BSO. This period could be a vulnerable time for women's cognitive health. While these findings need to be confirmed by a large prospective study, our research indicates that psychoeducation and awareness will be helpful in managing cognitive symptoms after surgical menopause.PMID:37751773 | DOI:10.1080/13697137.2023.2256659 (Source: Climacteric)
Source: Climacteric - September 26, 2023 Category: Geriatrics Authors: A Ramachandra E H X Thomas A J Vincent M Hickey N Warren J Kulkarni L E Forrest J Bojadzieva A Campbell C Gurvich Source Type: research

Global view of vasomotor symptoms and sleep disturbance in menopause: a systematic review
Climacteric. 2023 Sep 26:1-13. doi: 10.1080/13697137.2023.2256658. Online ahead of print.ABSTRACTStudies have shown racial/ethnic differences in the prevalence of vasomotor symptoms (VMS), sleep disturbance and VMS treatment in menopause. To assess the reproducibility of these differences, we systematically reviewed observational studies, published in 2000-2021, reporting the prevalence/incidence of VMS, sleep disturbance or treatment use in menopausal women stratified by race/ethnicity. We screened 3799 records from PubMed and Embase and included 27 papers (19 studies). No incidence data were found. Prevalence data varied...
Source: Climacteric - September 26, 2023 Category: Geriatrics Authors: S A Kingsberg R Schulze-Rath C Mulligan C Moeller C Caetano J Bitzer Source Type: research

Lack of evidence that progesterone in ovulatory cycles causes breast cancer
Climacteric. 2023 Sep 6:1-4. doi: 10.1080/13697137.2023.2249813. Online ahead of print.ABSTRACTA recent Perspective article asserted that progesterone secretion during ovulatory cycles is the cause of breast cancer. However, we challenge most of the evidence developed in this publication. First, there is a lack of evidence that progesterone is mutagenic for breast cells. Cause of a cancer should mean initiation by mutation, as opposed to promotion. Second, subclinical ovulatory disturbances occur rather frequently in normal-length menstrual cycles. Third, the authors attribute a potential carcinogenic effect to progesteron...
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: A Gompel V Seifert-Klauss J A Simon J C Prior Source Type: research

World Menopause Day
Climacteric. 2023 Oct;26(5):409-410. doi: 10.1080/13697137.2023.2247269.NO ABSTRACTPMID:37671974 | DOI:10.1080/13697137.2023.2247269 (Source: Climacteric)
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: Rod Baber Source Type: research

What is the evidence for the effect of physical exercise on bone health in menopausal women? An umbrella systematic review
In conclusion, jumping exercises were efficient in the hip, while aerobic and resistance exercises are still inconsistent. Concurrent training showed improvements in BMD of the lumbar spine, femoral neck, Ward's triangle and trochanter. Finally, combined resistance protocols are effective in preserving BMD of the femoral neck and lumbar spine in postmenopausal women.PMID:37673101 | DOI:10.1080/13697137.2023.2249819 (Source: Climacteric)
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: D Y Fausto J B B Martins A C Machado P S Saraiva A Pelegrini A C A Guimar ães Source Type: research

Lack of evidence that progesterone in ovulatory cycles causes breast cancer
Climacteric. 2023 Sep 6:1-4. doi: 10.1080/13697137.2023.2249813. Online ahead of print.ABSTRACTA recent Perspective article asserted that progesterone secretion during ovulatory cycles is the cause of breast cancer. However, we challenge most of the evidence developed in this publication. First, there is a lack of evidence that progesterone is mutagenic for breast cells. Cause of a cancer should mean initiation by mutation, as opposed to promotion. Second, subclinical ovulatory disturbances occur rather frequently in normal-length menstrual cycles. Third, the authors attribute a potential carcinogenic effect to progesteron...
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: A Gompel V Seifert-Klauss J A Simon J C Prior Source Type: research

World Menopause Day
Climacteric. 2023 Oct;26(5):409-410. doi: 10.1080/13697137.2023.2247269.NO ABSTRACTPMID:37671974 | DOI:10.1080/13697137.2023.2247269 (Source: Climacteric)
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: Rod Baber Source Type: research

What is the evidence for the effect of physical exercise on bone health in menopausal women? An umbrella systematic review
In conclusion, jumping exercises were efficient in the hip, while aerobic and resistance exercises are still inconsistent. Concurrent training showed improvements in BMD of the lumbar spine, femoral neck, Ward's triangle and trochanter. Finally, combined resistance protocols are effective in preserving BMD of the femoral neck and lumbar spine in postmenopausal women.PMID:37673101 | DOI:10.1080/13697137.2023.2249819 (Source: Climacteric)
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: D Y Fausto J B B Martins A C Machado P S Saraiva A Pelegrini A C A Guimar ães Source Type: research

Lack of evidence that progesterone in ovulatory cycles causes breast cancer
Climacteric. 2023 Sep 6:1-4. doi: 10.1080/13697137.2023.2249813. Online ahead of print.ABSTRACTA recent Perspective article asserted that progesterone secretion during ovulatory cycles is the cause of breast cancer. However, we challenge most of the evidence developed in this publication. First, there is a lack of evidence that progesterone is mutagenic for breast cells. Cause of a cancer should mean initiation by mutation, as opposed to promotion. Second, subclinical ovulatory disturbances occur rather frequently in normal-length menstrual cycles. Third, the authors attribute a potential carcinogenic effect to progesteron...
Source: Climacteric - September 6, 2023 Category: Geriatrics Authors: A Gompel V Seifert-Klauss J A Simon J C Prior Source Type: research