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Specialty: Endocrinology
Condition: Stroke

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Total 2154 results found since Jan 2013.

Genetic variation at the IGF1 locus shows association to post-stroke outcome and to circulating IGF-I.
CONCLUSION: Variation in rs7136446 of the IGF1 gene associates with post-stroke outcome in relatively young IS patients. Also, rs7136446 associates with s-IGF-I in controls but not in IS, which indicates that IS perturbs a normal genetic impact on s-IGF-I levels. PMID: 24005314 [PubMed - as supplied by publisher]
Source: European Journal of Endocrinology - September 4, 2013 Category: Endocrinology Authors: Aberg ND, Olsson S, Aberg D, Jood K, Stanne TM, Nilsson M, Blomstrand C, Svensson J, Isgaard J, Jern C Tags: Eur J Endocrinol Source Type: research

Chromium supplementation improved post-stroke brain infarction and hyperglycemia.
In this study, we investigated whether post-stroke hyperglycemia involved chromium dynamic mobilization in a rat model of permanent focal cerebral ischemia and whether dietary supplement of chromium improved post-stroke injury and alterations. Stroke rats developed brain infarction, hyperglycemia, hyperinsulinemia, glucose intolerance, and insulin resistance. Post-stroke hyperglycemia was accompanied by elevated secretion of counter-regulatory hormones including glucagon, corticosterone, and norepinephrine, decreased insulin signaling in skeletal muscles, and increased hepatic gluconeogenesis. Correlation studies revealed ...
Source: Diabetes Metab - October 19, 2015 Category: Endocrinology Authors: Chen WY, Mao FC, Liu CH, Kuan YH, Lai NW, Wu CC, Chen CJ Tags: Metab Brain Dis Source Type: research

Paramedic Perspectives on Barriers to Prehospital Acute Stroke Recognition.
CONCLUSIONS: While challenges to stroke recognition in the field were slightly different for rural and urban EMS, participants concurred that timely, systematic feedback on individual patients and case-based training would strengthen early stroke recognition skills. PMID: 26855299 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - February 14, 2016 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Contemporary Prehospital Emergency Medical Services Response Times for Suspected Stroke in the United States.
CONCLUSIONS: In the United States, time from receipt of 9-1-1 calls to treatment center arrival takes a median of 36 minutes for stroke patients, an improvement upon previously published times. The fact that 22%-46% of EMS responses did not meet stroke guidelines highlights an opportunity for improvement. Future studies should examine EMS diagnostic accuracy nationally or regionally using outcomes based approaches, as accurate recognition of prehospital strokes is vital in order to improve response times, adhere to guidelines, and ultimately provide timely and effective stroke treatment. PMID: 26953776 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - March 13, 2016 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Hypertension and Diabetes Mellitus as a Predictive Risk Factors for Stroke
Conclusion after summarising all the studies mentioned in the paper, it can be established that hypertension and diabetes mellitus are a stroke risk factors and correlated in patients with atherosclerosis.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - March 19, 2018 Category: Endocrinology Source Type: research

Age and Sex Are Critical Factors in Ischemic Stroke Pathology.
Abstract Ischemic stroke is a devastating brain injury, resulting in high mortality and significant loss-of-function. Understanding the pathophysiology of ischemic stroke risk, mortality and functional loss is critical to novel therapeutic development. Age and sex have a complex and interactive effect on ischemic stroke risk and pathophysiology. Aging is the strongest non-modifiable risk factor for ischemic stroke, and aged stroke patients have higher mortality, morbidity and poorer functional recovery than their young counterparts. Importantly, patient age modifies the influence of patient sex in ischemic stroke....
Source: Endocrinology - July 11, 2018 Category: Endocrinology Authors: Roy-O'Reilly M, McCullough LD Tags: Endocrinology Source Type: research

Selected adipose tissue hormones in the blood of patients with ischemic cerebral stroke.
CONCLUSIONS: Higher resistin and chemerin blood concentrations significantly increase the risk of ischemic stroke. The level of stroke severity in the moment of its occurrence and its course do not depend on the concentrations of adipocytokines under analysis. PMID: 31851370 [PubMed - as supplied by publisher]
Source: Endokrynologia Polska - December 17, 2019 Category: Endocrinology Authors: Kazimierczak-Kabzińska AE, Kajdaniuk D, Siemińska L, Nowak M, Głogowska-Szeląg J, Borgiel-Marek H, Janyga S, Kos-Kudła B, Marek B Tags: Endokrynol Pol Source Type: research

The effect of dulaglutide on stroke: an exploratory analysis of the REWIND trial
Publication date: Available online 7 January 2020Source: The Lancet Diabetes & EndocrinologyAuthor(s): Hertzel C Gerstein, Robert Hart, Helen M Colhoun, Rafael Diaz, Mark Lakshmanan, Fady T Botros, Jeffrey Probstfield, Matthew C Riddle, Lars Rydén, Charles Messan Atisso, Leanne Dyal, Stephanie Hall, Alvaro Avezum, Jan Basile, Ignacio Conget, William C Cushman, Nicolae Hancu, Markolf Hanefeld, Petr Jansky, Matyas KeltaiSummaryBackgroundCardiovascular outcome trials have suggested that glucagon-like peptide 1 (GLP-1) receptor agonists might reduce strokes. We analysed the effect of dulaglutide on stroke within the researchi...
Source: The Lancet Diabetes and Endocrinology - January 9, 2020 Category: Endocrinology Source Type: research

Incidence and mortality of myocardial infarction and stroke in patients with hyperthyroidism: A nationwide cohort study in Korea.
CONCLUSIONS: Hyperthyroidism is associated with increased risk of MI and ischemic stroke, independent of cardiovascular risk factors. This association is prominent in subjects with age ≥50 years, in females and in non-obese group. Hyperthyroidism did not significantly affect the mortality of cardiovascular events. PMID: 32093587 [PubMed - as supplied by publisher]
Source: Thyroid : official journal of the American Thyroid Association - February 27, 2020 Category: Endocrinology Tags: Thyroid Source Type: research

Effect of Prestroke Glycemic Variability Estimated Glycated Albumin on Stroke Severity and Infarct Volume in Diabetic Patients Presenting With Acute Ischemic Stroke
Conclusions: Prestroke glucose variability estimated by GA was associated with an increased risk of severe initial stroke severity and large infarct volume in acute ischemic stroke patients with diabetes mellitus.
Source: Frontiers in Endocrinology - April 20, 2020 Category: Endocrinology Source Type: research

BMI modifies the association between serum HDL cholesterol and stroke in a hypertensive population without atrial fibrillation
ConclusionsWe found an inverse association between HDL-C and stroke only in the BMI  <  24 kg/m2 group. The finding suggested that BMI could modify the association between HDL-C and stroke in hypertensive populations without AF.
Source: Journal of Endocrinological Investigation - May 12, 2020 Category: Endocrinology Source Type: research

Accuracy and Implications of Hemorrhagic Stroke Recognition by Emergency Medical Services.
CONCLUSIONS: Among EMS-transported hemorrhagic stroke cases, stroke screen documentation was strongly associated with EMS stroke recognition, which was in turn associated with higher quality of EMS care and faster CT scans upon emergency department arrival. PMID: 33026277 [PubMed - as supplied by publisher]
Source: Prehospital Emergency Care - October 9, 2020 Category: Endocrinology Tags: Prehosp Emerg Care Source Type: research

Elevated triglyceride-glucose index predicts risk of incident ischaemic stroke: The Rural Chinese Cohort Study
CONCLUSION: Elevated TyG index is an independent predictor of ischaemic stroke in the general population, and insulin resistance may be positively associated with future stroke risk.PMID:33722769 | DOI:10.1016/j.diabet.2021.101246
Source: Diabetes and Metabolism - March 16, 2021 Category: Endocrinology Authors: Yang Zhao Haohang Sun Weidong Zhang Yuanlin Xi Xuezhong Shi Yongli Yang Lu Jie Ming Zhang Liang Sun Hu Dongsheng Source Type: research

Factors associated with stroke among patients with type 2 diabetes mellitus in China: a propensity score matched study
ConclusionsThe prevalence of stroke was high among T2DM in China. It is of great significance to strengthen comprehensive management of health-related behaviors including smoking cessation, moderate alcohol consumption, effective exercise, 6 –8 h of sleep duration, keeping normal weight and the prevention of hypertension and dyslipidemia to have sustained beneficial effects on improvements of stroke risk factors.
Source: Acta Diabetologica - June 14, 2021 Category: Endocrinology Source Type: research