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Specialty: Endocrinology
Condition: Stroke

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Total 2154 results found since Jan 2013.

Triglyceride-Glucose Index and the Risk of Stroke: A Systematic Review and Dose-Response Meta-Analysis
In conclusion, elevated TyG index is the independent risk factor for incident strokes (especially ischemic stroke). [...] Georg Thieme Verlag Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents  |  Abstract  |  Full text
Source: Hormone and Metabolic Research - March 11, 2022 Category: Endocrinology Authors: Feng, Xiao Yao, Yao Wu, Lingshan Cheng, Chang Tang, Qiaoqiao Xu, Shabei Tags: Endocrine Care Source Type: research

Research on Early Warning of Ischemic Stroke Based on Atherosclerosis Index Combined with Serum Markers
CONCLUSION: These findings may contribute to the development of new diagnostic methods of potential biomarkers in serum combined with atherosclerosis index, thereby providing early warning for the diagnosis of atherosclerosis-induced ischemic stroke, and may provide a pathogenesis of IS New insights.PMID:35349673 | DOI:10.1210/clinem/dgac176
Source: The Journal of Clinical Endocrinology and Metabolism - March 29, 2022 Category: Endocrinology Authors: Wenjie Zhou Shanze Li Guijiang Sun Lili Song Wenjun Feng Rui Li Hui Liu Yaqian Dong Siyu Chen Shenshen Yang Jing Li Yubo Li Source Type: research

Relationship between triglyceride –glucose index and carotid plaques in a high-stroke-risk population in southeast china: A population-based cross-sectional survey
ConclusionsAn elevated TyG index is a potential predictor of carotid plaques in the high-stroke-risk population older than 40 years.
Source: Frontiers in Endocrinology - October 12, 2022 Category: Endocrinology Source Type: research

High prevalence of non-alcoholic fatty liver disease in patients with a first episode of acute ischemic stroke. Impact on disability and death
ConclusionPresence of NAFLD did not impact on disability and death after the stroke. However, patients with a first episode of stroke showed a high prevalence of NAFLD, especially at intermediate ages, and therefore, screening for NAFLD should be advisable.
Source: Frontiers in Endocrinology - December 16, 2022 Category: Endocrinology Source Type: research

An elevated likelihood of stroke, ischemic heart disease, or heart failure in individuals with gout: a longitudinal follow-up study utilizing the National Health Information database in Korea
ConclusionThe present findings suggest that individuals with gout in the Korean population, particularly those aged ≥ 60 years, were more likely to have stroke, ischemic heart disease, or heart failure.
Source: Frontiers in Endocrinology - August 23, 2023 Category: Endocrinology Source Type: research

The DPP-4 Inhibitor Linagliptin Counteracts Stroke in the Normal and Diabetic Mouse Brain: A Comparison With Glimepiride.
Abstract Type 2 diabetes is a strong risk factor for stroke. Linagliptin is a dipeptidyl peptidase-4 (DPP-4) inhibitor in clinical use against type 2 diabetes. The aim of this study was to determine the potential antistroke efficacy of linagliptin in type 2 diabetic mice. To understand whether efficacy was mediated by glycemia regulation, a comparison with the sulfonylurea glimepiride was done. To determine whether linagliptin-mediated efficacy was dependent on a diabetic background, experiments in nondiabetic mice were performed. Type 2 diabetes was induced by feeding the mice a high-fat diet for 32 weeks. Mice w...
Source: Diabetes - December 17, 2012 Category: Endocrinology Authors: Darsalia V, Ortsäter H, Olverling A, Darlöf E, Wolbert P, Nyström T, Klein T, Sjöholm A, Patrone C Tags: Diabetes Source Type: research

Is Diabetes an Independent Risk Factor for In‐Hospital Complications after a Stroke?
ConclusionsAlthough IS patients with DM more often suffered IHCs, previous diagnosis of DM is not per se associated with the risk of IHCs. Stroke severity and on‐admission glycemia ≥155 mg/dl were the most significant predictors for the development of IHCs.
Source: Journal of Diabetes - September 30, 2014 Category: Endocrinology Authors: Andrés Cruz‐Herranz, Blanca Fuentes, Patricia Martínez‐Sánchez, Gerardo Ruiz‐Ares, Manuel Lara‐Lara, Borja Sanz‐Cuesta, Exuperio Díez‐Tejedor Tags: Original Article Source Type: research

Evaluation of low-dose aspirin for primary prevention of ischemic stroke among patients with diabetes: a retrospective cohort study
Conclusions: In this study of patients with diabetes, the use of low-dose aspirin showed an increased risk of hospitalization for ischemic stroke. These results suggest that low-dose aspirin use for the primary prevention of ischemic stroke should be reconsidered in patients with diabetes.
Source: Diabetology and Metabolic Syndrome - February 15, 2015 Category: Endocrinology Authors: Ye-Jee KimNam-Kyong ChoiMi-Sook KimJoongyub LeeYoosoo ChangJong-Mi SeongSun-Young JungJu-Young ShinJi-Eun ParkByung-Joo Park Source Type: research

Myocardial Infarction and Stroke Risk in Young Healthy Men Treated with Injectable Testosterone.
This study was conducted to examine the association between testosterone therapy and new myocardial infarction (MI) and stroke events in a series of patients treated at Low T Centers across the United States, consisting of mainly young (mean age = 46), otherwise, healthy men. Electronic medical records were queried between the years 2009 and 2014 to identify patients diagnosed with hypogonadism, MI, and stroke, as indicated by ICD-9 codes. The incidence of MI and stroke events was compared to community-based registries. 39,936 patients recruited from 40 Low T Centers across the United States were treated and 19,968 met eli...
Source: International Journal of Endocrinology - July 2, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Is diabetes an independent risk factor for in‐hospital complications after a stroke? 糖尿病是卒中后发生院内并发症的一个独立危险因素吗？
ConclusionsAlthough IS patients with DM more often suffered IHCs, previous diagnosis of DM is not per se associated with the risk of IHCs. Stroke severity and on‐admission glycemia ≥155 mg/dL were the most significant predictors for the development of IHCs. 摘要 背景：与没有糖尿病（DM）的患者相比，DM患者更有可能发生院内并发症（in‐hospital complications，IHCs）。另外，他们发生缺血性卒中（ischemic stroke，IS）后的预后更差。我们的目的是评估IS患者发生IHCs的风险增加是否是因为DM本身，还是因为DM导致的代谢指标控制不佳或是...
Source: Journal of Diabetes - December 1, 2014 Category: Endocrinology Authors: Andrés Cruz‐Herranz, Blanca Fuentes, Patricia Martínez‐Sánchez, Gerardo Ruiz‐Ares, Manuel Lara‐Lara, Borja Sanz‐Cuesta, Exuperio Díez‐Tejedor Tags: Original Article Source Type: research

Potentials of incretin‐based therapies in dementia and stroke in type 2 diabetes mellitus
In conclusion, experimental studies show promising results of incretin‐based therapies at improving the outcome of Alzheimer's disease and stroke through glucose‐independent pleiotropic effects on the brain. If these findings would indeed be confirmed in large clinical randomized controlled trials, this would have substantial impact. This article is protected by copyright. All rights reserved.
Source: Journal of Diabetes Investigation - August 24, 2015 Category: Endocrinology Authors: Onno. N. Groeneveld, L. Jaap. Kappelle, Geert Jan Biessels Tags: Review Source Type: research

Is diabetes an independent risk factor for in‐hospital complications after a stroke? / 糖尿病是卒中后发生院内并发症的一个独立危险因素吗？
ConclusionsAlthough IS patients with DM more often suffered IHCs, previous diagnosis of DM is not per se associated with the risk of IHCs. Stroke severity and on‐admission glycemia ≥155 mg/dL were the most significant predictors for the development of IHCs. 摘要 背景：与没有糖尿病（DM）的患者相比，DM患者更有可能发生院内并发症（in‐hospital complications，IHCs）。另外，他们发生缺血性卒中（ischemic stroke，IS）后的预后更差。我们的目的是评估IS患者发生IHCs的风险增加是否是因为DM本身，还是因为DM导致的代谢指标控制不佳或是...
Source: Journal of Diabetes - December 1, 2014 Category: Endocrinology Authors: Andrés Cruz‐Herranz, Blanca Fuentes, Patricia Martínez‐Sánchez, Gerardo Ruiz‐Ares, Manuel Lara‐Lara, Borja Sanz‐Cuesta, Exuperio Díez‐Tejedor Tags: Original Article Source Type: research

Prior treatment with dipeptidyl peptidase 4 inhibitors is associated with better functional outcome and lower in-hospital mortality in patients with type 2 diabetes mellitus admitted with acute ischaemic stroke
In conclusion, prior treatment with dipeptidyl peptidase 4 inhibitors in patients with acute ischaemic stroke appears to be associated with better functional outcome and lower mortality risk.
Source: Diabetes and Vascular Disease Research - October 22, 2015 Category: Endocrinology Authors: Tziomalos, K., Bouziana, S. D., Spanou, M., Kostaki, S., Papadopoulou, M., Giampatzis, V., Dourliou, V., Kostourou, D.-T., Savopoulos, C., Hatzitolios, A. I. Tags: Brief Reports Source Type: research

Gliptin‐mediated neuroprotection against stroke requires chronic pretreatment and is independent of glucagon‐like peptide‐1 receptor
Gliptins are anti‐type 2 diabetes (T2D) drugs that regulate glycaemia by preventing endogenous glucagon‐like peptide‐1 (GLP‐1) degradation. Chronically administered gliptins before experimental stroke can also induce neuroprotection, and this effect is potentially relevant for reducing brain damage in patients with T2D and high risk of stroke. It is not known, however, whether acute gliptin treatment after stroke (mimicking a post‐hospitalization treatment) is neuroprotective or whether gliptin‐mediated neuroprotection occurs via GLP‐1‐receptor (GLP‐1R) activation. To answer these two questions, wild‐ty...
Source: Diabetes, Obesity and Metabolism - March 17, 2016 Category: Endocrinology Authors: V. Darsalia, M. Larsson, G. Lietzau, D. Nathanson, T. Nyström, T. Klein, C. Patrone Tags: RESEARCH LETTER Source Type: research