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Specialty: Endocrinology
Condition: Stroke
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Total 2154 results found since Jan 2013.
Glycemic Control in Hospitalized Stroke Patients: A Review
AbstractPurpose of ReviewThe purpose of this review is to discuss clinical trials involving glycemic control in hospitalized stroke patients and to review oral medications used in glycemic control. GLP-1 agonists, which have some preliminary studies in ischemic stroke, will also be reviewed.Recent FindingsUntil recently, glycemic control targets in hospitalized stroke patients remained unclear. The SHINE (Stroke Hyperglycemia Insulin Network Effort) trial demonstrated no significant difference between aggressive versus standard of care glycemic control in the acute ischemic stroke patient.SummaryAlthough SHINE demonstrated...
Source: Current Diabetes Reports - December 1, 2021 Category: Endocrinology Source Type: research
Related factors based on non-targeted metabolomics methods in minor ischaemic stroke
ConclusionIncreased levels of lactic acid, pyruvate, and TMAO may be related to the pathophysiological changes in the minor ischaemic stroke population. High blood pressure, a lack of physical activity, smoking, and increased TMAO level were the influencing factors for the occurrence of minor ischaemic stroke. The serum metabolite TMAO may be associated with MS occurrence
Source: Frontiers in Endocrinology - September 14, 2022 Category: Endocrinology Source Type: research
Association between diabetes mellitus and post ‐stroke cognitive impairment
PSD and PSCI impose heavy burdens on patients, families, and society. However, cognitive function after stroke is dynamic and dysfunction is often overlooked. Impaired fasting glucose, prediabetes, type 2 DM, hypoglycemia, and glycemic variability may lead to cognitive dysfunction after stroke via various mechanisms and pathways. There is emerging evidence regarding the association between different DM medications and cognitive functions. However, their relationship with the PSCI/PSD warrants further investigation. AbstractStroke survivors suffer from various physical, emotional, and cognitive impairments. These changes ar...
Source: Journal of Diabetes Investigation - October 1, 2022 Category: Endocrinology Authors: Kang ‐Po Lee,
Jung‐Sheng Chen,
Chih‐Yuan Wang Tags: Mini Review Source Type: research
Development and validation of risk prediction models for stroke and mortality among patients with type 2 diabetes in northern China
ConclusionIn this study, we developed and validated first-ever risk prediction models for stroke and death from stroke in patients with T2DM, with good discrimination and calibration observed in all models. Based on lifestyle, demographic characteristics, and laboratory examination, these models could provide multidimensional management and individualized risk assessment. However, the models developed here may only be applicable to Han Chinese.
Source: Journal of Endocrinological Investigation - January 20, 2023 Category: Endocrinology Source Type: research
SGLT2 inhibitors: Effect on myocardial infarction and stroke in type 2 diabetes
J Clin Endocrinol Metab. 2023 Feb 28:dgad113. doi: 10.1210/clinem/dgad113. Online ahead of print.ABSTRACTBACKGROUND: SGLT2 inhibitors (sodium-glucose cotransporter-2 inhibitors) have recently been recommended as preferred agents for management of hyperglycemia in type 2 diabetes, primarily based on their ability to reduce a composite of major cardiovascular adverse events (3P MACE), predominantly by reducing cardiovascular death. However reduction of the individual components, myocardial infarction (MI) or stroke (fatal and non-fatal) events have not been well explored.METHODS: In this meta-analysis, we included data avail...
Source: The Journal of Clinical Endocrinology and Metabolism - March 1, 2023 Category: Endocrinology Authors: Pradip Mukhopadhyay Debmalya Sanyal Purushottam Chatterjee Kaushik Pandit Sujoy Ghosh Source Type: research
Effects of the COVID-19 pandemic on prehospital emergency care for adults with stroke and transient ischaemic attack: A systematic review and meta-analysis
ConclusionsOur review indicates that prehospital delays for suspected stroke/TIA increased during the COVID-19 pandemic. Furthermore, emergency call volume for suspected stroke/TIA decreased during this period. In order to minimise delays in future pandemics or other health care emergencies future research may involve understanding the potential reasons for these delays.PMID:37261801 | DOI:10.1080/10903127.2023.2219729
Source: Prehospital Emergency Care - June 1, 2023 Category: Endocrinology Authors: Edel Burton Johnny Aladkhen Cathal O'Donnell Siobh án Masterson Áine Merwick Vera Jc McCarthy Patricia M Kearney Claire M Buckley Source Type: research
Incidence of Stroke in People With Diabetes Compared to Those Without
Diabetes: A Systematic Review
Conclusion The considerable differences between results can partly be
explained by differences in study designs, statistical methods, definitions of
stroke, and methods used to identify patients with diabetes. The lack of
evidence arising from these differences ought to be rectified by new
studies. [...] Georg Thieme Verlag KG Rüdigerstraße 14, 70469 Stuttgart, GermanyArticle in Thieme eJournals: Table of contents | Abstract | open access Full text
Source: Experimental and Clinical Endocrinology and Diabetes - July 17, 2023 Category: Endocrinology Authors: Kvitkina, Tatjana Narres, Maria Claessen, Heiner Metzendorf, Maria-Inti Richter, Bernd Icks, Andrea Tags: Review Source Type: research
Activation of hepatic inflammatory pathways by catecholamines is associated with hepatic insulin resistance in male ischemic stroke rats.
Abstract
Patients who experience acute ischemic stroke may develop hyperglycemia, even in the absence of diabetes. In the current study we determined the effects of acute stroke on hepatic insulin signaling, tumor necrosis factor α (TNF-α) expression, endoplasmic reticulum (ER) stress, the activities of c-Jun N-terminal kinase (JNK), inhibitor κB kinase β (IKK-β), and nuclear factor-κB (NF-κB) pathways. Rats with cerebral ischemia developed higher blood glucose, and insulin levels, and insulin resistance index, as well as hepatic gluconeogenic enzyme expression compared to the sham-treated group. The hepati...
Source: Endocrinology - January 17, 2014 Category: Endocrinology Authors: Wang YY, Lin SY, Chuang YH, Sheu WH, Tung KC, Chen CJ Tags: Endocrinology Source Type: research
Subclinical hypothyroidism and risk for incident ischemic stroke among postmenopausal women.
CONCLUSIONS: We found no evidence to suggest an association between SCH and ischemic stroke among healthy postmenopausal women.
PMID: 24827923 [PubMed - in process]
Source: Thyroid : official journal of the American Thyroid Association - November 14, 2014 Category: Endocrinology Tags: Thyroid Source Type: research
