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Specialty: Endocrinology
Condition: Stroke
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Brain to periphery in acute ischemic stroke: mechanisms and clinical significance
Front Neuroendocrinol. 2021 Jul 14:100932. doi: 10.1016/j.yfrne.2021.100932. Online ahead of print.ABSTRACTThe social and public health burdens of ischemic stroke have been increasing worldwide. In addition to focal brain damage, acute ischemic stroke (AIS) provokes systemic abnormalities across peripheral organs within the body. AIS profoundly alters the autonomic nervous system, hypothalamic-pituitary-adrenal axis, and immune system, which further yield deleterious organ-specific consequences. Poststroke systemic pathological alterations in turn considerably contribute to the progression of ischemic brain injury, which a...
Source: Frontiers in Neuroendocrinology - July 17, 2021 Category: Endocrinology Authors: Pan Cui Louise D McCullough Junwei Hao Source Type: research
