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Autoimmune thyroid disease during pregnancy
Publication date: Available online 12 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Simone De Leo, Elizabeth N Pearce Understanding of changes in thyroid function and the consequences of thyroid disease during pregnancy has rapidly grown in the past two decades, and revised American Thyroid Association guidelines on this topic were published in 2017. This Review explores the association between thyroid autoimmunity and complications during and after pregnancy. Thyroid autoimmunity refers to the presence of antibodies to thyroperoxidase or thyroglobulin, or thyroid-stimulating hormone receptor...
Source: The Lancet Diabetes and Endocrinology - December 13, 2017 Category: Endocrinology Source Type: research

Effect of once-daily, modified-release hydrocortisone versus standard glucocorticoid therapy on metabolism and innate immunity in patients with adrenal insufficiency (DREAM): a single-blind, randomised controlled trial
Publication date: Available online 8 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Andrea M Isidori, Mary Anna Venneri, Chiara Graziadio, Chiara Simeoli, Daniela Fiore, Valeria Hasenmajer, Emilia Sbardella, Daniele Gianfrilli, Carlotta Pozza, Patrizio Pasqualetti, Stefania Morrone, Angela Santoni, Fabio Naro, Annamaria Colao, Rosario Pivonello, Andrea Lenzi Background Conventional treatment of patients with adrenal insufficiency involves administration of glucocorticoids multiple times a day and has been associated with weight gain and metabolic impairment. The optimal glucocorticoid replacem...
Source: The Lancet Diabetes and Endocrinology - December 9, 2017 Category: Endocrinology Source Type: research

Turning back the clock on adrenal insufficiency
Publication date: Available online 8 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Gudmundur Johannsson (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 9, 2017 Category: Endocrinology Source Type: research

Advanced neuroendocrine tumours of the small intestine and pancreas: clinical developments, controversies, and future strategies
We describe advances in genetics, blood-based biomarkers, functional imaging, and systemic therapy of advanced NETs and discuss results of recent phase 3 studies, systemic treatment of advanced disease with peptide receptor radionuclide therapy, biotherapy, chemotherapy, and molecularly targeted therapy, and the potential role of immunotherapy in the treatment of NETs. Suggested treatment algorithms for NETs of ileal or jejunal origin and of pancreatic origin are presented. (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 9, 2017 Category: Endocrinology Source Type: research

Repaglinide versus insulin for newly diagnosed diabetes in patients with cystic fibrosis: a multicentre, open-label, randomised trial
Publication date: Available online 5 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Manfred Ballmann, Dominique Hubert, Baroukh M Assael, Doris Staab, Alexandra Hebestreit, Lutz Naehrlich, Tanja Nickolay, Nicole Prinz, Reinhard W Holl Background As survival among patients with cystic fibrosis has improved in recent decades, complications have become increasingly relevant. The most frequent complication is cystic-fibrosis-related diabetes. The recommended treatment is injected insulin, but some patients are treated with oral antidiabetic drugs to ease the treatment burden. We assessed the effic...
Source: The Lancet Diabetes and Endocrinology - December 6, 2017 Category: Endocrinology Source Type: research

Cardiovascular outcomes with glucagon-like peptide-1 receptor agonists in patients with type 2 diabetes: a meta-analysis
Publication date: Available online 6 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): M Angelyn Bethel, Rishi A Patel, Peter Merrill, Yuliya Lokhnygina, John B Buse, Robert J Mentz, Neha J Pagidipati, Juliana C Chan, Stephanie M Gustavson, Nayyar Iqbal, Aldo P Maggioni, Peter Öhman, Neil R Poulter, Ambady Ramachandran, Bernard Zinman, Adrian F Hernandez, Rury R Holman Background Glucagon-like peptide-1 (GLP-1) receptor agonists are effective glucose-lowering drugs. Findings from cardiovascular outcome trials showed cardiovascular safety of GLP-1 receptor agonists, but results for cardiovasc...
Source: The Lancet Diabetes and Endocrinology - December 6, 2017 Category: Endocrinology Source Type: research

GLP-1 receptor agonists: differentiation within the class
Publication date: Available online 6 December 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Simeon I Taylor (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 6, 2017 Category: Endocrinology Source Type: research

Worldwide burden of cancer attributable to diabetes and high body-mass index: a comparative risk assessment
Publication date: Available online 28 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Jonathan Pearson-Stuttard, Bin Zhou, Vasilis Kontis, James Bentham, Marc J Gunter, Majid Ezzati Background Diabetes and high body-mass index (BMI) are associated with increased risk of several cancers, and are increasing in prevalence in most countries. We estimated the cancer incidence attributable to diabetes and high BMI as individual risk factors and in combination, by country and sex. Methods We estimated population attributable fractions for 12 cancers by age and sex for 175 countries in 2012. We defined...
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Diabetes and adiposity: a heavy load for cancer
Publication date: Available online 28 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Yikyung Park, Graham A Colditz (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Cystic-fibrosis-related diabetes: time for oral drugs?
Publication date: Available online 30 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Antoinette Moran (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Frequency and phenotype of type 1 diabetes in the first six decades of life: a cross-sectional, genetically stratified survival analysis from UK Biobank
Publication date: Available online 30 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Nicholas J Thomas, Samuel E Jones, Michael N Weedon, Beverley M Shields, Richard A Oram, Andrew T Hattersley Background Type 1 diabetes is typically considered a disease of children and young adults. Genetic susceptibility to young-onset type 1 diabetes is well defined and does not predispose to type 2 diabetes. It is not known how frequently genetic susceptibility to type 1 diabetes leads to a diagnosis of diabetes after age 30 years. We aimed to investigate the frequency and phenotype of type 1 diabetes resu...
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Genetics and biobanks converge to resolve a vexing knowledge gap in diabetes
Publication date: Available online 30 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Jose C Florez (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2016; 4: 1004 –16
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2016; 4: 963 –64
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2017; 5: 864 –76
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

transCampus London –Dresden: a new model for international collaborative research
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 Author(s): Fiona Mitchell (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Atrial fibrillation and type 1 diabetes – Authors' reply
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 Author(s): Marcus Lind, Annika Rosengren (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Atrial fibrillation and type 1 diabetes
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 Author(s): Qianrui Li, Zhenmei An, Haoming Tian, Sheyu Li (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Good value care: when less is more
Publication date: December 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 12 Author(s): The Lancet Diabetes & Endocrinology (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - December 1, 2017 Category: Endocrinology Source Type: research

Using big data for non-communicable disease surveillance
Publication date: Available online 13 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Ran D Balicer, Miguel Luengo-Oroz, Chandra Cohen-Stavi, Enrique Loyola, Frederiek Mantingh, Liudmyla Romanoff, Gauden Galea (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - November 14, 2017 Category: Endocrinology Source Type: research

Primary aldosteronism and cardiovascular risk, before and after treatment
Publication date: Available online 9 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): John W Funder (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - November 10, 2017 Category: Endocrinology Source Type: research

Cardiovascular events and target organ damage in primary aldosteronism compared with essential hypertension: a systematic review and meta-analysis
Publication date: Available online 9 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Silvia Monticone, Fabrizio D'Ascenzo, Claudio Moretti, Tracy Ann Williams, Franco Veglio, Fiorenzo Gaita, Paolo Mulatero Background There is conflicting evidence, relying on heterogeneous studies, as to whether aldosterone excess is responsible for an increased risk of cardiovascular and cerebrovascular complications in patients with primary aldosteronism. We aimed to assess the association between primary aldosteronism and adverse cardiac and cerebrovascular events, target organ damage, diabetes, and metabolic...
Source: The Lancet Diabetes and Endocrinology - November 10, 2017 Category: Endocrinology Source Type: research

Cardiometabolic outcomes and mortality in medically treated primary aldosteronism: a retrospective cohort study
Publication date: Available online 9 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Gregory L Hundemer, Gary C Curhan, Nicholas Yozamp, Molin Wang, Anand Vaidya Background Mineralocorticoid receptor (MR) antagonists are the recommended medical therapy for primary aldosteronism. Whether this recommendation effectively reduces cardiometabolic risk is not well understood. We aimed to investigate the risk of incident cardiovascular events in patients with primary aldosteronism treated with MR antagonists compared with patients with essential hypertension. Methods We did a cohort study using patien...
Source: The Lancet Diabetes and Endocrinology - November 10, 2017 Category: Endocrinology Source Type: research

Research digest: hypoglycaemia and glucose variability
Publication date: Available online 8 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Naveed Sattar, David Preiss (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - November 9, 2017 Category: Endocrinology Source Type: research

Follicular thyroid cancer and H ürthle cell carcinoma: challenges in diagnosis, treatment, and clinical management
Publication date: Available online 5 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Giorgio Grani, Livia Lamartina, Cosimo Durante, Sebastiano Filetti, David S Cooper Follicular thyroid cancer is the second most common differentiated thyroid cancer histological type and has been overshadowed by its more common counterpart—papillary thyroid cancer—despite its unique biological behaviour and less favourable outcomes. In this Review, we comprehensively review the literature on follicular thyroid cancer to provide an evidence-based guide to the management of these tumours, to highlight...
Source: The Lancet Diabetes and Endocrinology - November 6, 2017 Category: Endocrinology Source Type: research

Effect of vitamin D supplementation on non-skeletal disorders: a systematic review of meta-analyses and randomised trials
Publication date: Available online 5 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Philippe Autier, Patrick Mullie, Alina Macacu, Miruna Dragomir, Magali Boniol, Kim Coppens, Cécile Pizot, Mathieu Boniol Randomised trials reported up to Dec 31, 2012, did not confirm that vitamin D supplementation could protect from non-skeletal health conditions affecting adults, as was expected on the basis of data from observational studies. To examine whether the more recently published meta-analyses and trials would change past conclusions, we systematically reviewed meta-analyses of vitamin D supp...
Source: The Lancet Diabetes and Endocrinology - November 6, 2017 Category: Endocrinology Source Type: research

Paricalcitol and albuminuria: tread carefully
Publication date: Available online 2 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Beatriz Fernandez-Fernandez, Alberto Ortiz (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - November 3, 2017 Category: Endocrinology Source Type: research

Moderate salt restriction with or without paricalcitol in type 2 diabetes and losartan-resistant macroalbuminuria (PROCEED): a randomised, double-blind, placebo-controlled, crossover trial
This study is registered with ClinicalTrials.gov, number NCT01393808, and the European Union Clinical Trials Register, number 2011-001713-14. Findings Between Dec 13, 2011, and Feb 17, 2015, we randomly allocated 57 (50%) patients to a low-sodium diet (28 [49%] to paricalcitol then placebo and 29 [51%] to placebo then paricalcitol) and 58 (50%) to a high-sodium diet (29 [50%] to paricalcitol then placebo and 29 [50%] to placebo then paricalcitol). In the low-sodium group (30 mEq of daily sodium intake reduction, equivalent to approximately 1·7–1·8 g per day), 24 h albuminuria was reduced by 36·6%...
Source: The Lancet Diabetes and Endocrinology - November 3, 2017 Category: Endocrinology Source Type: research

Cardiovascular risk factors and carotid intima media thickness in young adults born small for gestational age after cessation of growth hormone treatment: a 5-year longitudinal study
Publication date: Available online 1 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Manouk van der Steen, Gerthe F Kerkhof, Carolina C J Smeets, Anita C S Hokken-Koelega Background Growth hormone treatment reduces blood pressure and lipid concentrations. We assessed long-term changes in blood pressure, lipid concentrations, and carotid intima media thickness over a 5-year period after cessation of growth hormone treatment in adults born small for gestational age. Methods We did a longitudinal observational study at a medical centre in the Netherlands between April 1, 2004, and April 1, 2016. W...
Source: The Lancet Diabetes and Endocrinology - November 2, 2017 Category: Endocrinology Source Type: research

Cardiovascular risk after cessation of growth hormone treatment in people born small for gestational age
Publication date: Available online 1 November 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Rosario Pivonello, Carolina Di Somma, Annamaria Colao (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - November 2, 2017 Category: Endocrinology Source Type: research

Top ten research priorities for type 2 diabetes: results from the Diabetes UK –James Lind Alliance Priority Setting Partnership
Publication date: Available online 30 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sarah Finer, Paul Robb, Katherine Cowan, Ann Daly, Elizabeth Robertson, Andrew Farmer (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 30, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2017; 5: 887 –97
Publication date: November 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 11 (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 29, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2017; 5: 877 –86
Publication date: November 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 11 (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 29, 2017 Category: Endocrinology Source Type: research

Sex disparities in diabetes: bridging the gap
Publication date: November 2017 Source:The Lancet Diabetes & Endocrinology, Volume 5, Issue 11 Author(s): The Lancet Diabetes & Endocrinology (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 29, 2017 Category: Endocrinology Source Type: research

How can we optimise diabetes care in real-world practice?
Publication date: Available online 24 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Juliana C N Chan (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 25, 2017 Category: Endocrinology Source Type: research

Effect of an intensified multifactorial intervention on cardiovascular outcomes and mortality in type 2 diabetes (J-DOIT3): an open-label, randomised controlled trial
This study is registered with ClinicalTrials.gov, number NCT00300976. Findings Between June 16, 2006, and March 31, 2009, 2542 eligible patients were randomly assigned to intensive therapy or conventional therapy (1271 in each group) and followed up for a median of 8·5 years (IQR 7·3–9·0). Two patients in the intensive therapy group were found to be ineligible after randomisation and were excluded from the analyses. During the intervention period, mean HbA1c, systolic blood pressure, diastolic blood pressure, and LDL cholesterol concentrations were significantly lower in the intensive therapy gro...
Source: The Lancet Diabetes and Endocrinology - October 25, 2017 Category: Endocrinology Source Type: research

Interventions to prevent global childhood overweight and obesity: a systematic review
Publication date: Available online 20 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sara N Bleich, Kelsey A Vercammen, Laura Y Zatz, Johannah M Frelier, Cara B Ebbeling, Anna Peeters In view of the prevalence, health consequences, and costs of childhood obesity, there has been substantial interest in identifying effective interventions to prevent excess weight gain in young people. In this systematic review, we expand on previous reviews of obesity prevention interventions by including recent studies (until May 23, 2017) from all parts of the world. We searched MEDLINE, Embase, CINAHL Plus, We...
Source: The Lancet Diabetes and Endocrinology - October 21, 2017 Category: Endocrinology Source Type: research

Correction to Lancet Diabetes Endocrinol 2017; published online Sept 29. http://dx.doi.org/10.1016/S2213-8587(17)30239-5
Publication date: Available online 20 October 2017 Source:The Lancet Diabetes & Endocrinology (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 21, 2017 Category: Endocrinology Source Type: research

Bone and mineral disorders in chronic kidney disease: implications for cardiovascular health and ageing in the general population
Publication date: Available online 16 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Adrian Covic, Marc Vervloet, Ziad A Massy, Pablo Ureña Torres, David Goldsmith, Vincent Brandenburg, Sandro Mazzaferro, Pieter Evenepoel, Jordi Bover, Mugurel Apetrii, Mario Cozzolino The patient with chronic kidney disease (CKD) represents an extreme model for arteriosclerosis, vascular calcification, and bone disorders, all of which are also associated with ageing in the general population. These pathological features are also relevant to other common chronic health disorders such as diabetes, and chro...
Source: The Lancet Diabetes and Endocrinology - October 17, 2017 Category: Endocrinology Source Type: research

Omega-6 fatty acid biomarkers and incident type 2 diabetes: pooled analysis of individual-level data for 39  740 adults from 20 prospective cohort studies
Publication date: Available online 12 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Jason H Y Wu, Matti Marklund, Fumiaki Imamura, Nathan Tintle, Andres V Ardisson Korat, Janette de Goede, Xia Zhou, Wei-Sin Yang, Marcia C de Oliveira Otto, Janine Kröger, Waqas Qureshi, Jyrki K Virtanen, Julie K Bassett, Alexis C Frazier-Wood, Maria Lankinen, Rachel A Murphy, Kalina Rajaobelina, Liana C Del Gobbo, Nita G Forouhi, Robert Luben, Kay-Tee Khaw, Nick Wareham, Anya Kalsbeek, Jenna Veenstra, Juhua Luo, Frank B Hu, Hung-Ju Lin, David S Siscovick, Heiner Boeing, Tzu-An Chen, Brian Steffen, Lyn M St...
Source: The Lancet Diabetes and Endocrinology - October 12, 2017 Category: Endocrinology Source Type: research

Is the new treatment for Cushing's disease too sweet?
Publication date: Available online 12 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Ashley Grossman (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 12, 2017 Category: Endocrinology Source Type: research

Linoleic acid and risk of type 2 diabetes
Publication date: Available online 12 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Gabriele Riccardi (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 12, 2017 Category: Endocrinology Source Type: research

Efficacy and safety of once-monthly pasireotide in Cushing's disease: a 12 month clinical trial
We report results of the first phase 3 trial assessing long-acting intramuscular pasireotide in patients with Cushing's disease. Methods In this phase 3 clinical trial we recruited patients aged 18 years or older with persistent, recurrent, or de-novo (non-surgical candidates) Cushing's disease who had a mean urinary free cortisol (mUFC) concentration (from three 24 h samples) of 1·5–5·0 times the upper limit of normal (ULN), a normal or greater than normal morning plasma adrenocorticotropic hormone concentration, and a pituitary source of Cushing's syndrome, from 57 sites across 19 countries. Exclusion...
Source: The Lancet Diabetes and Endocrinology - October 12, 2017 Category: Endocrinology Source Type: research

Iodine supplementation in pregnancy in mildly deficient regions
Publication date: Available online 10 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sarah C Bath (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 11, 2017 Category: Endocrinology Source Type: research

Effect of iodine supplementation in pregnant women on child neurodevelopment: a randomised, double-blind, placebo-controlled trial
Publication date: Available online 10 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sueppong Gowachirapant, Nidhi Jaiswal, Alida Melse-Boonstra, Valeria Galetti, Sara Stinca, Ian Mackenzie, Susan Thomas, Tinku Thomas, Pattanee Winichagoon, Krishnamachari Srinivasan, Michael B Zimmermann Background Iodine deficiency during pregnancy might be associated with reduced intelligence quotient (IQ) score in offspring. We assessed the effect of iodine supplementation in mildly iodine-deficient pregnant women on neurodevelopment of their offspring in areas where schoolchildren were iodine sufficient. Me...
Source: The Lancet Diabetes and Endocrinology - October 11, 2017 Category: Endocrinology Source Type: research

Improving the clinical impact of randomised trials in thyroidology
Publication date: Available online 10 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Tim I M Korevaar, Layal Chaker, Robin P Peeters (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 11, 2017 Category: Endocrinology Source Type: research

SGLT2 inhibitors: hypotheses on the mechanism of cardiovascular protection
Publication date: Available online 10 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Robert M Bell, Derek M Yellon (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 11, 2017 Category: Endocrinology Source Type: research

Clinical inertia versus overtreatment in glycaemic management
Publication date: Available online 9 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Kamlesh Khunti, Melanie J Davies (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 10, 2017 Category: Endocrinology Source Type: research

Sugar: the prime suspect in poor health
Publication date: Available online 4 October 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Talha Khan Burki (Source: The Lancet Diabetes and Endocrinology)
Source: The Lancet Diabetes and Endocrinology - October 5, 2017 Category: Endocrinology Source Type: research

Diabetes structured self-management education programmes: a narrative review and current innovations
Publication date: Available online 29 September 2017 Source:The Lancet Diabetes & Endocrinology Author(s): Sudesna Chatterjee, Melanie J Davies, Simon Heller, Jane Speight, Frank J Snoek, Kamlesh Khunti Both type 1 and type 2 diabetes are associated with long-term complications that can be prevented or delayed by intensive glycaemic management. People who are empowered and skilled to self-manage their diabetes have improved health outcomes. Over the past 20 years, diabetes self-management education programmes have been shown to be efficacious and cost-effective in promotion and facilitation of self-management, wit...
Source: The Lancet Diabetes and Endocrinology - September 30, 2017 Category: Endocrinology Source Type: research