rs7903146 (C/T) polymorphism of Transcription factor 7 like 2 (TCF7L-2) gene is independently associated with non-alcoholic fatty liver disease in Asian Indians
This study was designed to investigate the association of rs7903146 (C/T) polymorphism of TCF7L-2 gene with non-alcoholic fatty liver disease (NAFLD) in Asian Indians.MethodsIn this case-control study 162 non-diabetic subjects with NAFLD and 173 body mass index (BMI)-matched controls without NAFLD were recruited. Abdominal ultrasound, clinical and biochemical investigations, fasting insulin levels and value of homeostasis model assessment of insulin resistance (HOMA-IR) was measured. Single nucleotide polymorphism rs7903146 (C/T) was genotyped by polymerase chain reaction–restriction fragment length polymorphisms.Res...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 22, 2020 Category: Endocrinology Source Type: research

Diabetes-related research in India and other south Asian countries is inadequate requiring more funding, coaching and structure
Publication date: March–April 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 2Author(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 22, 2020 Category: Endocrinology Source Type: research

Prediction of body fat in Sri Lankan adults: Development and validation of a skinfold thickness equation
Publication date: March–April 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 2Author(s): Ranil Jayawardena, Yasindu C. Waniganayake, Sachith A. Abhayaratna, Priyanga RanasingheAbstractObjectiveThe study aimed to develop and validate a percentage body fat (%BF) prediction equation using SFT for Sri Lankan adults.MethodsHealthy adults (≥18 years) were randomly selected and SFT was measured in five areas (triceps, biceps, calf, suprailliac and subscapular). Body composition analysis was evaluated by Deuterium oxide (D2O) dilution. Prediction equation for %BF was deriv...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 21, 2020 Category: Endocrinology Source Type: research

Evolutionary trends in bacteria isolated from moderate and severe diabetic foot infections in a Portuguese tertiary center
ConclusionThere was an increase in the prevalence of neuroischemic DFU. The Enterobacteriaceae family replaced SA as the most prevalent pathogen in DFI, with an increase in the isolation of gram-negative microorganisms and mixed polymicrobial cultures. Chronic neuroischemic infected ulcers usually present distinct bacterial isolates; knowledge about the most common agents is warranted in order to better select empiric antibiotic therapy. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 19, 2020 Category: Endocrinology Source Type: research

Whither diabetes research in India TODAY?
ConclusionsConsidering major health and economic problems posed by unrestrained diabetes epidemic in India, research in this area remains highly inadequate. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 19, 2020 Category: Endocrinology Source Type: research

Diabetes-related Research in India and other South Asian Countries is Inadequate Requires More Funding, Coaching and Structure
Publication date: Available online 14 February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 15, 2020 Category: Endocrinology Source Type: research

I rely more on self-monitoring of blood glucose than HbA1c to assess diabetes control. Do you?
Publication date: Available online 14 February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Kanika Tyagi (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 15, 2020 Category: Endocrinology Source Type: research

GAS: The Glycemia (Diabetes) Awareness and Insight Scale
ConclusionsOverall, the GAS is a novel and easy-to-administer scale that comprehensively measures subjective illness awareness in persons with T2DM. As the first scale of its kind, the GAS holds promise for use in epidemiology studies to examine the extent to which impaired illness awareness or illness denial contributes to clinical outcomes and T2DM management. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 15, 2020 Category: Endocrinology Source Type: research

Use of more expensive insulin despite guidelines in Brazil
ConclusionThe guidelines are not being followed for most patients analyzed, which may result in unnecessary expenses for the SUS. Therefore, this data can support the awareness of prescribers in relation to the savings generated for municipalities through the follow-up of the guidelines. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 12, 2020 Category: Endocrinology Source Type: research

The Health Effects of Saturated Fats – The Role of Whole Foods and Dietary Patterns
Publication date: Available online 6 February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Deepinder Kaur, Dina A. Tallman, Pramod KhoslaAbstractThe effects of saturated fat on cardiovascular health have been studied for more than half a century. While simple public health messages have been to avoid and/or limit their intake, the underlying research is more complex. It is apparent that the effects of saturated fat on health are dependent both on the presence of other nutrients as well as the associated dietary pattern. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 7, 2020 Category: Endocrinology Source Type: research

Prediction of Body Fat in Sri Lankan adults: Development and validation of skinfold thickness equation
Publication date: Available online 5 February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Ranil Jayawardena, Yasindu C. Waniganayake, Sachith A. Abhayaratna, Priyanga RanasingheAbstractObjectiveThe study aimed to develop and validate a percentage body fat (%BF) prediction equation using SFT for Sri Lankan adults.MethodsHealthy adults (≥18 years) were randomly selected and SFT was measured in five areas (triceps, biceps, calf, suprailliac and subscapular). Body composition analysis was evaluated by Deuterium oxide (D2O) dilution. Prediction equation for %BF was derived by line...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 6, 2020 Category: Endocrinology Source Type: research

Escalating cost of oral and injectable antihyperglycemic drugs; are newer medications worth their price? A perspective from India and other developing countries
Publication date: Available online 4 February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Atul Luthra, Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 5, 2020 Category: Endocrinology Source Type: research

Depression among Peruvian adults with hypertension and diabetes: analysis of a national survey
ConclusionPeru has a considerable burden of depression in the hypertensive and diabetic populations. While the variables positively associated with depression in hypertensive adults were female gender and harmful alcohol consumption, in adults with diabetes it was the presence of physical disability. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 5, 2020 Category: Endocrinology Source Type: research

Altered adipocytokine profile predicts early stage of left ventricular remodeling in hypertensive patients with type 2 diabetes mellitus
ConclusionWe found that serum levels of omentin-1 and ZA2G were the most important predictors for LV hypertrophy + LV diastolic dysfunction in T2DM patients. Large clinical trials are required to confirm this assumption and get clear explanation of issues unveiled. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 5, 2020 Category: Endocrinology Source Type: research

Association between reduced serum levels of magnesium and the presence of poor glycemic control and complications in type 1 diabetes mellitus: A systematic review and meta-analysis
ConclusionThere is an association between reduced levels of magnesium and poor glycemic control in patients with type 1 diabetes mellitus, however, this needs further studies. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - February 1, 2020 Category: Endocrinology Source Type: research

Dr. Shaukat Sadikot: Obituaries
Publication date: January–February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 1Author(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

If only lifestyle compliance of Indian patients with diabetes is better, we could have lot less morbidities and deaths
Publication date: January–February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 1Author(s): Juhi Mittal, Bhavya Arora, Koel Dutta, Kanika Tyagi, Aanchal Gupta (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Way forward for the Journal in times of escalating challenges
Publication date: January–February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 1Author(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Editorial Board
Publication date: January–February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 1Author(s): (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Human pancreatic tissue dissociation enzymes for islet isolation: advances and clinical perspectives
Conclusions: This review presents information focusing on properties and role of TDE blends during the islet isolation process, particularly emphasizing on the current developments, associated challenges and future perspectives within the field. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Effect of cinnamon supplementation on blood pressure and anthropometric parameters in patients with type 2 diabetes: A systematic review and meta-analysis of clinical trials
ConclusionsCinnamon supplementation significantly decreased SBP and DBP of patients with type 2 diabetes. Although cinnamon intake caused changes in anthropometric parameters, the observed changes were not statistically significant. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Mango: A fruit too far in patients with diabetes? (or is it?)
Publication date: Available online 31 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Sugandha Kehar, Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Should we count dietary cholesterol in dairy products? A perspective from India and South Asia
Publication date: Available online 31 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Juhi Mittal (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 31, 2020 Category: Endocrinology Source Type: research

Comparison of body mass index and metabolic parameters with serum vaspin levels in women with polycystic ovary syndrome
This study showed that there is a positive correlation between serum Visceral Adipose tissue derived Serine Protease Inhibitor (VASPIN) level and polycystic ovary syndrome (PCOS). In previous studies, this relation was attributed to the generalization of higher amount of adipose tissue in patients with PCOS. However, we detected that VASPIN is significantly high in patients with PCOS regardless of BMI. We also showed that metabolic parameters such as fasting insulin, HOMA-IR, triglycerides and LDL-C levels were increased in lean women with PCOS. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 29, 2020 Category: Endocrinology Source Type: research

Management of Asymptomatic Hyperuricemia: Integrated Diabetes & Endocrine Academy (IDEA) consensus statement
ConclusionRecommendations were made on important areas such as definition, investigation and management of asymptomatic hyperuricemia. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 18, 2020 Category: Endocrinology Source Type: research

The impact of structured self-monitoring of blood glucose on glycaemic variability in non-insulin treated type 2 diabetes: the SMBG study, a 12-month randomised controlled trial
Publication date: Available online 13 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): David M. Williams, Sharon N. Parsons, Gareth J. Dunseath, Jeffrey W. Stephens, Stephen D. Luzio, David R. OwensAbstractAimsThere is inconsistent evidence supporting the self-monitoring of blood glucose (SMBG) in people with non-insulin treated type 2 diabetes (T2D). Our aim was to determine the impact of structured SMBG on simple measures of glycaemic variability (GV) in people with T2D.MethodsParticipants undertook structured SMBG over 12 months, with HbA1c recorded at baseline and at 3-mo...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 14, 2020 Category: Endocrinology Source Type: research

Dietary Cholesterol Advisory from American Heart Association: Implications for India and Other Developing Countries
Publication date: Available online 10 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 10, 2020 Category: Endocrinology Source Type: research

Effects of low glycemic index/high-fat, high-calorie diet on glycemic control and lipid profiles of children and adolescence with cystic fibrosis: A randomized double-blind controlled clinical trial
Publication date: Available online 8 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Zahra Gorji, Mohammadreza Modaresi, Saeed Yekanni-Nejad, Maryam MahmoudiPurposeLow glycemic index diets seem to be potentially effective to improve glycemic control and reduce lipid profiles. Hence, this study aimed to evaluate the effect of a low glycemic index/high fat, high-calorie diet on glycemic status and lipid profiles of patients with cystic fibrosis.MethodsIn this randomized clinical trial, 44 children and adolescents with cystic fibrosis were randomized to receive for three months...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 9, 2020 Category: Endocrinology Source Type: research

Expression of neutrophil elastase and myeloperoxidase mRNA in patients with newly diagnosed type 2 diabetes mellitus
ConclusionsIt was concluded that type 2 diabetes mellitus is associated with a decrease in neutrophil elastase and myeloperoxidase gene expression in the PBL. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 9, 2020 Category: Endocrinology Source Type: research

The effects of Curcumin supplementation on oxidative stress, Sirtuin-1 and Peroxisome proliferator activated receptor γ coactivator 1α gene expression in polycystic ovarian syndrome (PCOS) patients: a randomized placebo-controlled clinical trial
ConclusionsCurcumin seems to be an efficient reducer of oxidative stress related complications in patients with PCOS. Further studies on curcumin should strengthen our findings. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 9, 2020 Category: Endocrinology Source Type: research

Hyperpigmentation and Thickening of Skin with Callosity Formation over Dorsum of Both Feet and Healed Ulceration over Left Lateral Malleolus in a Patient with Type 2 Diabetes Performing Prolonged Prayers
We describe such lesions in a 62-year-old Muslim patient with uncontrolled glycemia who practiced prolonged, repeated religious prayers in sitting position causing significant pressure over dorsum of both ankles. He developed prayer-induced callous formation on dorsum of both ankles, with more thickening and a healed ulcer on left. Prayer-induced skin lesions should be carefully managed in patients with diabetes, who are more vulnerable for infections and gangrene due to as venous/arterial insufficiency and peripheral neuropathy. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 3, 2020 Category: Endocrinology Source Type: research

Gender difference in the association between Framingham Risk Score with cardio-metabolic risk factors and psychological distress in patients with metabolic syndrome
Publication date: Available online 3 January 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Mahdieh Abbasalizad Farhangi, Leila JahangiryAbstractBackgroundIn the current study we aimed to evaluate the gender-specific associations between metabolic and psychological risk factors of cardiovascular disease (CVD) and Framingham Risk Score (FRS) in patients with metabolic syndrome.MethodsIn a cross-sectional study of 256 patients with metabolic syndrome (157 men, 99 women), the cardiovascular disease risk was evaluated using the FRS scoring system by a pre-defined computerized algorithm...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - January 3, 2020 Category: Endocrinology Source Type: research

Impact of flash glucose monitoring on glycaemic control and quality of life in patients with type 1 diabetes: a 18-month follow-up in real life
Publication date: Available online 23 December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): S. Rouhard, M. Buysschaert, O. Alexopoulou, V. PreumontAbstractWe conducted a prospective observational study to evaluate the medium-term impact of the flash glucose monitoring system (FGM) in a type 1 diabetic population. We included 248 patients, switched from conventional blood glucose monitoring (BGM) to FGM. We evaluated glycaemic control at 2-4 (T1) and 5-11 (T2) months after initiation and at the last available visit (T3, 18±4 months). We asked patients to fill in, at T0 and ...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 24, 2019 Category: Endocrinology Source Type: research

Way forward for theJournalin times of escalating challenges
Publication date: January–February 2020Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 14, Issue 1Author(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 24, 2019 Category: Endocrinology Source Type: research

Self-management based coaching program to improve diabetes mellitus self-management practice and metabolic markers among uncontrolled type 2 diabetes mellitus in Indonesia: A quasi-experimental study
This study aimed to examine the effectiveness of the diabetes mellitus self-management (DMSM) based coaching program on improvement of the DMSM practice and metabolic markers. A quasi-experimental study, pre-test, and post-test design with the non-equivalent control group were applied in this study. Sixty samples were selected and were randomly assigned to both the experimental group and the control group. The Diabetes Self-Management Questionnaire (DSMQ) was used to measure the DMSM practice, while metabolic biomarkers were assessed by using the laboratory test. We conducted and compared the DMSM practice and clinical val...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 18, 2019 Category: Endocrinology Source Type: research

Way forward for Journal in Times of Escalating Challenges
Publication date: Available online 14 December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 15, 2019 Category: Endocrinology Source Type: research

Innovations and proactive political commitment are required to combat diabetes in India and other developing countries
Publication date: Available online 13 December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Hema S. Gopalan, Anoop Misra (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 14, 2019 Category: Endocrinology Source Type: research

Cardiorespiratory fitness, muscular fitness and metabolic syndrome with special reference to glucose intolerance
Publication date: Available online 13 December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Tomoyuki Kawada (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 14, 2019 Category: Endocrinology Source Type: research

Immediate postoperative complications following coronary artery bypass grafting in patients with type 2 diabetes: a prospective cohort study
ConclusionsA significant number of patients with T2DM developed acute kidney injury following CABG. There was no difference in infective complications such as pneumonia and catheter-associated urinary tract infection, between the two groups. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 14, 2019 Category: Endocrinology Source Type: research

Editorial Board
Publication date: November–December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & Reviews, Volume 13, Issue 6Author(s): (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 7, 2019 Category: Endocrinology Source Type: research

The Chemical Exposome of Type 2 Diabetes Mellitus: Opportunities and Challenges in the Omics Era
Publication date: Available online 6 December 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Biswapriya B. Misra, Anoop MisraAbstractT2DM, variously known as diabetes mellitus type 2, adult-onset diabetes; noninsulin-dependent diabetes mellitus (NIDDM) is a global silent killer, with> 450 million adults affected worldwide. A diverse array of non-modifiable risk factors such as family history, age (>45 yrs), race/ethnicity, and history of gestational diabetes) and modifiable risk factors such as physical inactivity, high body fat or body weight, high blood pressure and high ch...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - December 6, 2019 Category: Endocrinology Source Type: research

Surrogate Indexes of Insulin Resistance and Risk of Metabolic Syndrome in non-Hispanic White, non-Hispanic Black and Mexican American
CONCLUSIONSTG-WC in NHW and NHB, and LAP in MA are more powerful than other proxies of IR in predicting MetS. TG-WC and LAP can serve as adjunctive tools for screening for MetS in NHW, NHB, and MA. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 26, 2019 Category: Endocrinology Source Type: research

Comparison of salivary nitric oxide and oral health in diabetic patients with and without xerostomia
ConclusionsThe present study indicates salivary nitric oxide level was a predictor of xerostomia in diabetic patients. More longitudinal studies are necessary to understand the association of salivary NO level with diabetes-induced xerostomia. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 26, 2019 Category: Endocrinology Source Type: research

Association Between Serum Transaminase Levels And Insulin Resistance In Euthyroid And Non-Diabetic Adults
ConclusionElevated serum levels of ALT were associated with insulin resistance. ALT could be used in clinical practice as an additional tool to assess insulin resistance in apparently healthy people. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 26, 2019 Category: Endocrinology Source Type: research

Clinical trials among Arab diabetic patients; the challenges
Publication date: Available online 21 November 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Ehab Mudher Mikhael, Mohammed Azmi Hassali, Saad A. Hussain (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 22, 2019 Category: Endocrinology Source Type: research

C-PEPTIDE concentrations in patients with type 2 diabetes treated with insulin
ConclusionIn this study, almost all patients with type 2 diabetes using insulin were found to have sufficient or borderline beta cell reserves. Our findings suggest a need to reexamine the practice of such widespread use of insulin in the treatment of patients with non-insulinopenic type 2 diabetes. and insulin resistance-related parameters were prominent in those with adequate beta cell reserve. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 20, 2019 Category: Endocrinology Source Type: research

“Diabetes care at Doorsteps”: A customised mobile van for the prevention, screening, detection and management of diabetes in the urban underprivileged populations of Delhi
Publication date: Available online 20 November 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Hema S. Gopalan, Intazaamul-Haq, Shamshad Ahmad, Ashok Gaur, Anoop MisraAbstractDiabetes is on the rise in India and recently shown to be increasing in the urban underprivileged. Lack of awareness of the disease, its complications, combined with lack of financial resources among the underprivileged, often results in late detection and more complications in them. To combat this, healthcare delivered at the doorstep through the use of a customised mobile medical van is a potentially attracti...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 20, 2019 Category: Endocrinology Source Type: research

Underweight and overweight or obesity and associated factors among school-going adolescents in five ASEAN countries, 2015
ConclusionHigh prevalences of underweight and overweight/obesity were identified in ASEAN countries and several correlates were identified which can help to tailor interventions. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 15, 2019 Category: Endocrinology Source Type: research

Serum cystatin C as an early marker of nephropathy among type 2 diabetics: a meta-analysis
ConclusionSerum CysC is shown to be a superior biomarker in the early diagnosis of DN. However, further studies are still needed to verify our claims. (Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews)
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 15, 2019 Category: Endocrinology Source Type: research

The Prevalence of Comorbid Depression in Patients with Diabetes: A Meta-Analysis of Observational Studies
Publication date: Available online 14 November 2019Source: Diabetes & Metabolic Syndrome: Clinical Research & ReviewsAuthor(s): Mahdieh Sedighi Pashaki, Jamal Asad Mezel, Zahra Mokhtari, Reza Ghanei Gheshlagh, Parisa Shahbazi Hesabi, Taban Nematifard, Soore KhakiAbstractDepression is one of the most common psychiatric disorders in patients with diabetes, which can exacerbate and accelerate adverse diabetes complaints by reducing self-care behaviors and medication adherence. The purpose of this study is to estimate the prevalence of depression in Iranian patients with diabetes. The search was conducted in the databa...
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - November 15, 2019 Category: Endocrinology Source Type: research