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Specialty: Endocrinology
Condition: Diabetes

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Total 1416 results found since Jan 2013.

Effect of Prestroke Glycemic Variability Estimated Glycated Albumin on Stroke Severity and Infarct Volume in Diabetic Patients Presenting With Acute Ischemic Stroke
Conclusions: Prestroke glucose variability estimated by GA was associated with an increased risk of severe initial stroke severity and large infarct volume in acute ischemic stroke patients with diabetes mellitus.
Source: Frontiers in Endocrinology - April 20, 2020 Category: Endocrinology Source Type: research

Elevated triglyceride-glucose index predicts risk of incident ischaemic stroke: The Rural Chinese Cohort Study
CONCLUSION: Elevated TyG index is an independent predictor of ischaemic stroke in the general population, and insulin resistance may be positively associated with future stroke risk.PMID:33722769 | DOI:10.1016/j.diabet.2021.101246
Source: Diabetes and Metabolism - March 16, 2021 Category: Endocrinology Authors: Yang Zhao Haohang Sun Weidong Zhang Yuanlin Xi Xuezhong Shi Yongli Yang Lu Jie Ming Zhang Liang Sun Hu Dongsheng Source Type: research

Factors associated with stroke among patients with type 2 diabetes mellitus in China: a propensity score matched study
ConclusionsThe prevalence of stroke was high among T2DM in China. It is of great significance to strengthen comprehensive management of health-related behaviors including smoking cessation, moderate alcohol consumption, effective exercise, 6 –8 h of sleep duration, keeping normal weight and the prevention of hypertension and dyslipidemia to have sustained beneficial effects on improvements of stroke risk factors.
Source: Acta Diabetologica - June 14, 2021 Category: Endocrinology Source Type: research

Thyroid Function within the Reference Range and the Risk of Stroke: An Individual Participant Data Analysis.
CONCLUSION: Higher levels of TSH within the reference range may decrease risk of stroke, highlighting the need for further research focusing on the clinical consequences associated with differences within the reference range of thyroid function. PMID: 27603906 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - September 6, 2016 Category: Endocrinology Authors: Chaker L, Baumgartner C, den Elzen WP, Collet TH, Ikram MA, Blum MR, Dehghan A, Drechsler C, Luben RN, Portegies ML, Iervasi G, Medici M, Stott DJ, Dullaart RP, Ford I, Bremner A, Newman AB, Wanner C, Sgarbi JA, Dörr M, Longstreth WT, Psaty BM, Ferrucci Tags: J Clin Endocrinol Metab Source Type: research

Dipeptidyl peptidase-4 inhibitors and protection against stroke: A systematic review and meta-analysis.
CONCLUSION: The promising data from experimental studies regarding cardioprotective gliptin-associated effects against stroke were not supported by available data from trials specifically looking at cardiovascular safety. PMID: 27916514 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - November 30, 2016 Category: Endocrinology Authors: Barkas F, Elisaf M, Tsimihodimos V, Milionis H Tags: Diabetes Metab Source Type: research

Correlation between CH2DS2-VASc Score and Serum Leptin Levels in Cardioembolic Stroke Patients: The Impact of Metabolic Syndrome.
Conclusion: This pilot study revealed that leptin could be a potential biomarker for risk stratification of cardioembolic stroke in MetS patients and that heterogeneity of stroke subtypes should be considered for more refined and precise clinical stroke studies. PMID: 29225622 [PubMed]
Source: International Journal of Endocrinology - December 13, 2017 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Hypertension and diabetes mellitus as a predictive risk factors for stroke
Conclusionafter summarising all the studies mentioned in the paper, it can be established that hypertension and diabetes mellitus are a stroke risk factors and correlated in patients with atherosclerosis.
Source: Diabetes and Metabolic Syndrome: Clinical Research and Reviews - July 23, 2018 Category: Endocrinology Source Type: research

GLP-1R activation for the treatment of stroke: Updating and future perspectives.
Abstract Stroke is the leading cause of adult disability in Westernized societies with increased incidence along ageing and it represents a major health and economical threat. Inactive lifestyle, smoking, hypertension, atherosclerosis, obesity and diabetes all dramatically increase the risk of stroke. While preventive strategies based on lifestyle changes and risk factor management can delay or decrease the likelihood of having a stroke, post stroke pharmacological strategies aimed at minimizing stroke-induced brain damage are highly needed. Unfortunately, several candidate drugs that have shown significant precli...
Source: ENDOCR REV - April 30, 2014 Category: Endocrinology Authors: Darsalia V, Nathanson D, Nyström T, Klein T, Sjöholm A, Patrone C Tags: Rev Endocr Metab Disord Source Type: research

Stroke risk in treatment of type 2 diabetes in China: a 7 year retrospective cohort study
Publication date: November 2016 Source:The Lancet Diabetes & Endocrinology, Volume 4, Supplement 1 Author(s): Rui Liu, Qing Wang, Vivian Szeto, Andrew Barszczyk, Tianru Jin, Edoardo Mannucci, Hong-Shuo Sun, Zhong-Ping Feng Background Diabetes and stroke are leading causes of death and disability, and major public health concerns in China, which accounts for 25% of patients with diabetes worldwide. Type 2 diabetes is an independent risk factor for cerebral ischaemia and accounts for about 20% of stroke cases. We previously showed that KATP channel activation provides neuroprotection against cerebral ischaemia and t...
Source: The Lancet Diabetes and Endocrinology - November 17, 2016 Category: Endocrinology Source Type: research

White matter injury induced by diabetes in acute stroke is clinically relevant: A preliminary study
The importance of white matter injury induced by diabetes in stroke severity and prognosis is largely unknown. We aimed to investigate the relationship between diabetes-related white matter injury beyond stroke lesions with acute neurological deficits and clinical outcome after stroke. In total, 36 stroke patients within 3–7 days after onset were enrolled. Neurological deficits on admission were assessed by National Institute of Health Stroke Score, and poor outcome at 3 months was defined as modified Rankin score >2. White matter tracts were compared between patients with diabetic and non-diabetic stroke using fr...
Source: Diabetes and Vascular Disease Research - December 8, 2016 Category: Endocrinology Authors: Yu, X., Song, R., Jiaerken, Y., Yuan, L., Huang, P., Lou, M., Jiang, Q., Zhang, M. Tags: Original Articles Source Type: research

Long-term risk of stroke in type 2 diabetes patients with diabetic ketoacidosis: A population-based, propensity score-matched, longitudinal follow-up study.
CONCLUSION: T2D patients with previous DKA have a higher risk of stroke, especially ischaemic strokes. PMID: 28129999 [PubMed - as supplied by publisher]
Source: Diabetes and Metabolism - January 23, 2017 Category: Endocrinology Authors: Chen YL, Weng SF, Yang CY, Wang JJ, Tien KJ Tags: Diabetes Metab Source Type: research

The Effect of Diabetes on Cortical Function in Stroke: Implications for Poststroke Plasticity
Diabetes may impair the capacity for neuroplasticity such that patients experience a slower and poorer recovery after stroke. The current study investigated changes in cortical function in stroke patients with diabetes to determine how this comorbidity may affect poststroke cortical plasticity and thereby functional recovery. From a cohort of 57 participants, threshold-tracking transcranial magnetic stimulation was used to assess cortical function over the ipsilateral and contralesional hemispheres in 7 patients with diabetes after an acute stroke compared with 12 stroke patients without diabetes. Cortical function was als...
Source: Diabetes - May 22, 2017 Category: Endocrinology Authors: Huynh, W.; Kwai, N.; Arnold, R.; Krishnan, A. V.; Lin, C. S.- Y.; Vucic, S.; Kiernan, M. C. Tags: Pathophysiology Source Type: research

Regional differences in the prevalence of coronary heart disease and stroke in patients with type 2 diabetes in China.
Conclusions: There were large variations in risks of CHD, stroke and composite of both in T2DM in China with Northeast and North having the highest risks. PMID: 29982638 [PubMed - as supplied by publisher]
Source: The Journal of Clinical Endocrinology and Metabolism - July 3, 2018 Category: Endocrinology Authors: Lyu Y, Luo Y, Li C, Guo X, Lu J, Wu H, Huo X, Gu W, Yang G, Ji L, Yang X Tags: J Clin Endocrinol Metab Source Type: research

Aspirin Versus Clopidogrel Monotherapy for the Secondary Prevention of Recurrent Cerebrovascular Attack Following Previous Ischemic Stroke in Patients with Type 2 Diabetes Mellitus: A Systematic Review and Meta-Analysis
ConclusionClopidogrel monotherapy was neither inferior nor superior to aspirin monotherapy for the secondary prevention of recurrent cerebrovascular attack following previous ischemic stroke in patients with T2DM. Hence, clopidogrel or aspirin monotherapy is equally safe and effective in these patients with T2DM.
Source: Diabetes Therapy - March 26, 2020 Category: Endocrinology Source Type: research