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Factors Influencing the Decline in Stroke Mortality: A Statement From the American Heart Association/American Stroke Association AHA/ASA Scientific Statement
Conclusions— The decline in stroke mortality is real and represents a major public health and clinical medicine success story. The repositioning of stroke from third to fourth leading cause of death is the result of true mortality decline and not an increase in mortality from chronic lung disease, which is now the third leading cause of death in the United States. There is strong evidence that the decline can be attributed to a combination of interventions and programs based on scientific findings and implemented with the purpose of reducing stroke risks, the most likely being improved control of hypertension. Thus, ...
Source: Stroke - December 23, 2013 Category: Neurology Authors: Lackland, D. T., Roccella, E. J., Deutsch, A. F., Fornage, M., George, M. G., Howard, G., Kissela, B. M., Kittner, S. J., Lichtman, J. H., Lisabeth, L. D., Schwamm, L. H., Smith, E. E., Towfighi, A., on behalf of the American Heart Association Stroke Coun Tags: AHA Statements and Guidelines AHA/ASA Scientific Statement Source Type: research

Rates and Determinants of 5-Year Outcomes After Atrial Fibrillation-Related Stroke: A Population Study Clinical Sciences
Conclusions— AF-stroke is associated with considerable long-term morbidity, fatality, stroke recurrence, and nursing home requirement. Adequately resourced national AF strategies to improve AF detection and prevention are needed.
Source: Stroke - November 23, 2015 Category: Neurology Authors: Hayden, D. T., Hannon, N., Callaly, E., Ni Chroinin, D., Horgan, G., Kyne, L., Duggan, J., Dolan, E., O'Rourke, K., Williams, D., Murphy, S., Kelly, P. J. Tags: Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Age and Ethnic Disparities in Incidence of Stroke Over Time: The South London Stroke Register Clinical Sciences
Conclusions— Total stroke incidence decreased during the 16-year time period. However, this was not seen in younger age groups and black groups. The advances in risk factor reduction observed in white groups aged >55 years failed to be transferred to younger age groups and black groups.
Source: Stroke - November 25, 2013 Category: Neurology Authors: Wang, Y., Rudd, A. G., Wolfe, C. D. A. Tags: Risk Factors for Stroke, Stroke in Children and the Young, Epidemiology Clinical Sciences Source Type: research

High Prevalence of Atrial Fibrillation Among Patients With Ischemic Stroke Clinical Sciences
Conclusions— Access to nationwide register data shows that AF is more common among patients with ischemic stroke than those previously reported. Few patients with stroke and AF had anticoagulant treatment before the event, and few got it after the event. CHA2DS2-VASc could be a useful monitoring tool to intensify efforts to diagnose AF among patients with cryptogenic stroke.
Source: Stroke - August 25, 2014 Category: Neurology Authors: Friberg, L., Rosenqvist, M., Lindgren, A., Terent, A., Norrving, B., Asplund, K. Tags: Coumarins, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Epidemiology Clinical Sciences Source Type: research

Associations Between Estimated Glomerular Filtration Rate and Stroke Outcomes in Diabetic Versus Nondiabetic Patients Clinical Sciences
Conclusions— Decreased eGFR (<45 mL/min per 1.73 m2) is a strong predictor of all-cause mortality, stroke recurrence, and stroke disability in diabetic and nondiabetic patients with acute stroke. Increased eGFR (≥120 mL/min per 1.73 m2) is associated with all of stroke outcomes in diabetic patients and linked to all-cause mortality in nondiabetic patients.
Source: Stroke - September 22, 2014 Category: Neurology Authors: Luo, Y., Wang, X., Matsushita, K., Wang, C., Zhao, X., Hu, B., Liu, L., Li, H., Liu, G., Jia, Q., Wang, Y., Wang, Y., on behalf of the CNSR Investigators Tags: Cerebrovascular disease/stroke, Risk Factors, Clinical Studies Clinical Sciences Source Type: research

Risk Factors of Ischemic Stroke and Subsequent Outcome in Patients Receiving Hemodialysis Clinical Sciences
Conclusions— Incidence of stroke is high in patients with ESRD on hemodialysis with high case-fatality. Incident hemodialysis patients had the highest stroke incidence. Many, but not all, important risk factors commonly associated with stroke in the general population were not associated with stroke in patients receiving hemodialysis.
Source: Stroke - August 24, 2015 Category: Neurology Authors: Findlay, M. D., Thomson, P. C., Fulton, R. L., Solbu, M. D., Jardine, A. G., Patel, R. K., Stevens, K. K., Geddes, C. C., Dawson, J., Mark, P. B. Tags: Cerebrovascular disease/stroke, Risk Factors for Stroke, Epidemiology Clinical Sciences Source Type: research

Role of Prestroke Vascular Pathology in Long-Term Prognosis After Stroke: The Rotterdam Study Clinical Sciences
Conclusions— One quarter of deaths after stroke could theoretically be prevented with rigorous cardiovascular prevention and treatment, but this should preferably start before stroke occurrence. In addition, research into factors explaining the remaining deaths needs to be encouraged.
Source: Stroke - December 28, 2015 Category: Neurology Authors: Portegies, M. L. P., Bos, M. J., Hofman, A., Heeringa, J., Franco, O. H., Koudstaal, P. J., Ikram, M. A. Tags: Epidemiology, Risk Factors, Mortality/Survival, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Trends in Age of First-Ever Stroke Following Increased Incidence and Life Expectancy in a Low-Income Chinese Population Clinical Sciences
Conclusions— The age of stroke onset tends to be younger among low-income population in China after the dramatic increased incidence of stroke during the gradual extension of life expectancy of population in China. These findings suggested that stroke burden will continue to increase in the long time, unless the risk factors in low-income populations are effectively controlled.
Source: Stroke - March 27, 2016 Category: Neurology Authors: Wang, J., Bai, L., Shi, M., Yang, L., An, Z., Li, B., Zhao, W., Gu, H., Zhan, C., Tu, J., Ning, X. Tags: Epidemiology, Lifestyle, Primary Prevention, Risk Factors, Cerebrovascular Disease/Stroke Clinical Sciences Source Type: research

Risk Stratification for Recurrence and Mortality in Embolic Stroke of Undetermined Source Clinical Sciences
Conclusions— The risk of recurrent ischemic stroke/TIA and death in ESUS is reliably stratified by CHADS2 and CHA2DS2-VASc scores. Compared with the low-risk group, patients in the high-risk CHA2DS2-VASc group have much higher risk of ischemic stroke recurrence/TIA and death, approximately 3-fold and 13-fold, respectively.
Source: Stroke - August 21, 2016 Category: Neurology Authors: Ntaios, G., Vemmos, K., Lip, G. Y. H., Koroboki, E., Manios, E., Vemmou, A., Rodriguez-Campello, A., Cuadrado-Godia, E., Giralt-Steinhauer, E., Arnao, V., Caso, V., Paciaroni, M., Diez-Tejedor, E., Fuentes, B., Perez Lucas, J., Arauz, A., Ameriso, S. F., Tags: Ischemic Stroke Clinical Sciences Source Type: research

One-Year Incidence, Time Trends, and Predictors of Recurrent Ischemic Stroke in Sweden From 1998 to 2010 Clinical Sciences
Conclusions—The risk of recurrent ischemic stroke decreased from 1998 to 2010. Well-known risk factors for stroke were associated with a higher risk of ischemic stroke recurrence; whereas, secondary preventive medication was associated with a reduced risk, emphasizing the importance of secondary preventive treatment.
Source: Stroke - July 24, 2017 Category: Neurology Authors: Lisa Bergstrom, Anna–Lotta Irewall, Lars Soderstrom, Joachim Ogren, Katarina Laurell, Thomas Mooe Tags: Epidemiology, Risk Factors, Secondary Prevention, Quality and Outcomes, Ischemic Stroke Original Contributions Source Type: research

Assessing the Performance of the Framingham Stroke Risk Score in the Reasons for Geographic and Racial Differences in Stroke Cohort Clinical Sciences
Conclusions— Although higher FSRS was associated with higher stroke risk, the FSRS overestimated the observed stroke rates in this study, particularly in certain subgroups. This may be because of temporal declines in stroke rates, secular trends in prevention treatments, or differences in populations studied. More accurate estimates of event rates are critical for planning research, including clinical trials, and targeting health-care efforts.
Source: Stroke - May 27, 2014 Category: Neurology Authors: McClure, L. A., Kleindorfer, D. O., Kissela, B. M., Cushman, M., Soliman, E. Z., Howard, G. Tags: Risk Factors for Stroke Clinical Sciences Source Type: research

Long-Term Risk and Predictors of Recurrent Stroke Beyond the Acute Phase Brief Reports
Conclusions— Despite declining recurrence rates in this relatively young stroke population, almost one third are either dead or have experienced a second stroke in 5 years.
Source: Stroke - May 27, 2014 Category: Neurology Authors: Pennlert, J., Eriksson, M., Carlberg, B., Wiklund, P.-G. Tags: Risk Factors for Stroke, Epidemiology Brief Reports Source Type: research

Predictors of Finding Occult Atrial Fibrillation After Cryptogenic Stroke Clinical Sciences
Conclusions— Mobile cardiac outpatient telemetry detects AF in a substantial proportion of cryptogenic stroke patients. Age >60 years and radiographic evidence of prior cortical or cerebellar infarction are robust indicators of occult AF. Patients with neither had a low prevalence of AF.
Source: Stroke - April 27, 2015 Category: Neurology Authors: Favilla, C. G., Ingala, E., Jara, J., Fessler, E., Cucchiara, B., Messe, S. R., Mullen, M. T., Prasad, A., Siegler, J., Hutchinson, M. D., Kasner, S. E. Tags: Acute Cerebral Infarction, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Pathology of Stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Electrocardiographic Left Atrial Abnormality and Risk of Stroke: Northern Manhattan Study Clinical Sciences
Conclusions— ECG-defined left atrial abnormality was associated with incident cryptogenic or cardioembolic stroke independently of the presence of AF, suggesting atrial thromboembolism may occur without recognized AF.
Source: Stroke - October 26, 2015 Category: Neurology Authors: Kamel, H., Hunter, M., Moon, Y. P., Yaghi, S., Cheung, K., Di Tullio, M. R., Okin, P. M., Sacco, R. L., Soliman, E. Z., Elkind, M. S. V. Tags: Electrocardiology, Echocardiography, Arrhythmias, clinical electrophysiology, drugs, Embolic stroke, Risk Factors for Stroke Clinical Sciences Source Type: research

Contribution of Established Stroke Risk Factors to the Burden of Stroke in Young Adults Clinical Sciences
Conclusions—Modifiable risk factors previously established in older populations also account for a large part of stroke in younger adults, with 4 risk factors explaining almost 80% of stroke risk.Clinical Trial Registration—URL: http://www.clinicaltrials.gov. Unique identifier: NCT00414583.
Source: Stroke - June 26, 2017 Category: Neurology Authors: Annette Aigner, Ulrike Grittner, Arndt Rolfs, Bo Norrving, Bob Siegerink, Markus A. Busch Tags: Epidemiology, Risk Factors, Cerebrovascular Disease/Stroke Original Contributions Source Type: research