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Specialty: Endocrinology
Condition: Diabetes

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Total 1416 results found since Jan 2013.

Clinical Characteristics and Outcomes of Acute Ischemic Stroke in Patients with Type 2 Diabetes: A Single-Center, Retrospective Study in Southern China
CONCLUSIONS: Type 2 DM is associated with AIS and its risk factors, such as dyslipidemia and hypertension. Patients in the AIS-DM group had less LAA and smaller arterial occlusions, and DM could exacerbate the short-term clinical outcomes in AIS patients.PMID:34234826 | PMC:PMC8216820 | DOI:10.1155/2021/5517228
Source: International Journal of Endocrinology - July 8, 2021 Category: Endocrinology Authors: Minrui Chen Weiliang Luo Jiming Li Kaiyi Cao Xiaohui Li Huihong Huang Yan He Source Type: research

Admission hyperglycemia, stroke subtypes, outcomes in acute ischemic stroke
Whether admission hyperglycemia is differentially associated with early vascular outcomes in acute ischemic stroke(AIS) depending on stroke subtype has been incompletely delineated.
Source: Diabetes Research and Clinical Practice - January 11, 2023 Category: Endocrinology Authors: Joon-Tae Kim, Ji Sung Lee, Beom Joon Kim, Jihoon Kang, Keon-Joo Lee, Jong-Moo Park, Kyusik Kang, Soo Joo Lee, Jae Guk Kim, Jae-Kwan Cha, Dae-Hyun Kim, Tai Hwan Park, Kyung Bok Lee, Jun Lee, Keun-Sik Hong, Yong-Jin Cho, Hong-Kyun Park, Byung-Chul Lee, Kyun Source Type: research

Testosterone Doesn't Up MI or Stroke: May Be Protective?Testosterone Doesn't Up MI or Stroke: May Be Protective?
Contrary to 2 widely publicized recent studies, a new retrospective review of data from 40 specialized centers with strict follow-up protocols found lower MI and stroke risks with testosterone. Medscape Medical News
Source: Medscape Diabetes Headlines - May 18, 2014 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Effect of diabetes on hospitalization for ischemic stroke and related in‐hospital mortality. A study in Tuscany, Italy, over years 2004‐2011
ConclusionsIn the last decade, the incidence of IS and of related in‐hospital mortality declined in persons without diabetes, while increasing among diabetic patients of advanced age. Diabetic females, compared to males, had a higher in‐hospital mortality risk. This article is protected by copyright. All rights reserved.
Source: Diabetes/Metabolism Research and Reviews - September 24, 2014 Category: Endocrinology Authors: Laura Policardo, Giuseppe Seghieri, Roberto Anichini, Alessandra De Bellis, Flavia Franconi, Paolo Francesconi, Stefano Del Prato, Edoardo Mannucci Tags: Research Article Source Type: research

Decreased Insulin Sensitivity and Impaired Fibrinolytic Activity in Type 2 Diabetes Patients and Nondiabetics with Ischemic Stroke.
Authors: Jotic A, Milicic T, Covickovic Sternic N, Kostic VS, Lalic K, Jeremic V, Mijajlovic M, Lukic L, Rajkovic N, Civcic M, Macesic M, Seferovic JP, Stanarcic J, Aleksic S, Lalic NM Abstract We analyzed (a) insulin sensitivity (IS), (b) plasma insulin (PI), and (c) plasminogen activator inhibitor-1 (PAI-1) in type 2 diabetes (T2D) patients with (group A) and without (group B) atherothrombotic ischemic stroke (ATIS), nondiabetics with ATIS (group C), and healthy controls (group D). IS was determined by minimal model (Si). Si was lower in A versus B (1.18 ± 0.67 versus 2.82 ± 0.61 min-1/mU/L × 104; P < 0.0...
Source: International Journal of Endocrinology - June 21, 2015 Category: Endocrinology Tags: Int J Endocrinol Source Type: research

Diabetes, Heart Attack, and Stroke a Lethal CombinationDiabetes, Heart Attack, and Stroke a Lethal Combination
The "cardiometabolic multimorbidity" represented by the troika of diabetes, stroke, and myocardial infarction raises the risk for death eightfold compared with people who have none of the three conditions. Medscape Medical News
Source: Medscape Diabetes Headlines - July 8, 2015 Category: Endocrinology Tags: Diabetes & Endocrinology News Source Type: news

Diabetic Stroke Severity: Epigenetic Remodeling and Neuronal, Glial, and Vascular Dysfunction
We determined the mechanism of severity during type 1 diabetic (T1D) stroke (ischemia-reperfusion [IR] injury) that affects potential markers associated with epigenetics, neuronal, glial, and vascular components of the brain with regard to nondiabetic stroke. The study used male genetic T1D Ins2+/– Akita and wild-type (C57BL/6J) mice. The experimental mice groups were 1) sham, 2) IR, 3) shamAkita, and 4) IRAkita. Mice were subjected to middle cerebral artery occlusion for 40 min, followed by reperfusion for 24 h. Brain tissues were analyzed for inflammation, neuro-glio-vascular impairments, matrix metalloproteinase (...
Source: Diabetes - November 24, 2015 Category: Endocrinology Authors: Kalani, A.; Kamat, P. K.; Tyagi, N. Tags: Complications Source Type: research

Family history of myocardial infarction, stroke and diabetes and cardiometabolic markers in children
Conclusions/interpretation One-third of the children had a strong family history of CVD and/or diabetes. These children had higher TC levels and TC/HDLC ratios than children with no family history. A strong family history of MI or diabetes was independently associated with unfavourable cardiometabolic markers specific to those diseases.
Source: Diabetologia - July 1, 2016 Category: Endocrinology Source Type: research

Plasma copeptin and functional outcome in patients with ischemic stroke and type 2 diabetes
In this study, we therefore evaluated the short-term prognostic value of early measurement of plasma copeptin levels in Chinese patients with type 2 diabetes mellitus (T2DM) and acute ischemic stroke (AIS).
Source: Journal of Diabetes and Its Complications - July 29, 2016 Category: Endocrinology Authors: Chi-Bo Wang, Miao Zong, Shi-Qing Lu, Zhuo Tian Source Type: research

Moyamoya syndrome causing stroke in young women with type 1 diabetes
Moyamoya syndrome is an idiopathic brain vasculopathy characterized by stenosis of major intracranial arteries. It often presents in patients with type 1 diabetes or thyroid disease and may have an autoimmune etiology. Moyamoya-related stroke poses a diagnostic challenge as initial symptoms and deficits vary greatly from classic ischemic stroke to encephalopathy, psychiatric, or seizure disorder.
Source: Journal of Diabetes and Its Complications - August 10, 2016 Category: Endocrinology Authors: Jing W. Hughes, Jennifer A. Wyckoff, Abby S. Hollander, Colin P. Derdeyn, Janet B. McGill Tags: Case Report Source Type: research

Pioglitazone in patients with insulin resistance after ischemic stroke or transient ischemic attack: A comment on the IRIS trial
Pioglitazone, an antidiabetic drug, also exerts several cardiometabolic benefits including antioxidant, anti-inflammatory, antihypertensive, vasoprotective and hypolipidemic effects. These pioglitazone-related benefits have been observed in different patient populations such as those with prediabetes, non-alcoholic fatty liver disease and type 2 diabetes mellitus (T2DM). With regard to cardiovascular (CV) morbidity and mortality, there is conflicting evidence.Recently, the Insulin Resistance Intervention after Stroke (IRIS) trial reported a significant pioglitazone-induced decrease in CV morbidity in patients with insulin ...
Source: Journal of Diabetes and Its Complications - September 17, 2016 Category: Endocrinology Authors: Niki Katsiki, Dimitri P Mikhailidis Source Type: research

Diabetes and lifetime risk of stroke and subtypes in an urban middle-aged population
Lifetime risk (LTR) is defined as the cumulative probability of developing a disease in one's remaining lifetime from a given index age. The impact of diabetes on the LTR of stroke events in Asians, where stroke incidence is higher than for Westerners, has not been estimated yet. These estimates can be useful for diabetes knowledge translation activities.
Source: Journal of Diabetes and Its Complications - February 9, 2017 Category: Endocrinology Authors: Tanvir Chowdhury Turin, Tomonori Okamura, Nahid Rumana, Arfan Raheen Afzal, Makoto Watanabe, Aya Higashiyama, Yoko M Nakao, Michikazu Nakai, Misa Takegami, Kunihiro Nishimura, Yoshihiro Kokubo, Akira Okayama, Yoshihiro Miyamoto Source Type: research

Establishment and validation of a prediction model for ischemic stroke risks in patients with type 2 diabetes
Diabetes is a formidable global health threat because of its high prevalence and numerous complications. Furthermore, diabetes is a leading cause of mortality and microvascular and macrovascular diseases, including coronary diseases, cerebrovascular diseases, and peripheral vascular diseases. A recent study reports that risk of stroke in patients with type 2 diabetes is two to five times higher than the general population[1]. The World Health Organization MONICA project reported that stroke incidence is higher among ethnic Chinese population than among Western population [2].
Source: Diabetes Research and Clinical Practice - February 17, 2018 Category: Endocrinology Authors: Tsai-Chung Li, Hsiang-Chi Wang, Chia-Ing Li, Chiu-Shong Liu, Wen-Yuan Lin, Chih-Hsueh Lin, Sing-Yu Yang, Cheng-Chieh Lin Source Type: research