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Nutrition: Iron

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Total 471 results found since Jan 2013.

Electroacupuncture Ameliorates Cerebral Ischemic Injury by Inhibiting Ferroptosis
Conclusion: Our results indicate that EA can inhibit ferroptosis by regulating oxidative stress and iron-related proteins, thus conferring protection against MCAO in a rat model.
Source: Frontiers in Neurology - March 8, 2021 Category: Neurology Source Type: research

Fish, Cardiovascular Disease, and Mortality
Fish and shellfish (hereafter referred to as fish) are major sources of the dietary long-chain ω-3 fatty acids eicosapentaenoic acid (20:5n-3) and docosahexaenoic acid (22:6n-3) and also contain other nutrients, such as vitamin D, riboflavin, iodine, calcium, phosphorus, magnesium, potassium, zinc, and iron. The summed results of observational studies of fish intake, randomized clinical tria ls of fish oil supplements, and associated mechanistic and experimental studies suggest that regular fish consumption may decrease the incidence of myocardial infarction (MI) and coronary heart disease (CHD), with more uncertain effec...
Source: JAMA Internal Medicine - March 8, 2021 Category: Internal Medicine Source Type: research

Effect Of n-amyl alcohol/biodiesel blended nano additives on the performance, combustion and emission characteristics of CRDi diesel engine
Environ Sci Pollut Res Int. 2021 Mar 6. doi: 10.1007/s11356-021-13165-5. Online ahead of print.ABSTRACTThis paper deals with the study on the influence of the effects of iron oxide nanoparticle additives when added to ternary fuel (diesel + mahua methyl ester + pentanol) on the emission, combustion, and performance characteristics of a four stroke, single cylinder, common rail direct injection diesel engine working at a constant speed and varying operating scenarios. Doping is done in various proportions to the nanoparticle additives with the help of a homogenizer and ultrasonicator where the cationic surfactant used is CT...
Source: Environmental Science and Pollution Research International - March 7, 2021 Category: Environmental Health Authors: Prabhu Kishore Nutakki Santhosh Kumar Gugulothu Jatoth Ramachander Mulugundam Sivasurya Source Type: research

Ferroptosis and its potential as a therapeutic target
Biochem Pharmacol. 2021 Feb 22:114486. doi: 10.1016/j.bcp.2021.114486. Online ahead of print.ABSTRACTFerroptosis is a recently defined form of programmed cell death that is different from apoptosis. It is an iron-dependent programmed cell death and the accumulation of lipid hydroperoxides to lethal levels make ferroptosis distinct. Ferroptosis can be effectively regulated by a number of cellular variables including iron content, amino acid uptake, polyunsaturated fatty acid incorporation, glutathione biosynthesis, and NADPH levels. A number of severe and common degenerative diseases in humans such as Parkinson's disease an...
Source: Biochemical Pharmacology - February 25, 2021 Category: Drugs & Pharmacology Authors: Hanshu Yuan Justin Pratte Charles Giardina Source Type: research

Dynamic changes of inflammation and apoptosis in  cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging.
Dynamic changes of inflammation and apoptosis in cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging. Mol Med Rep. 2021 Apr;23(4): Authors: Zhuang L, Kong Y, Yang S, Lu F, Gong Z, Zhan S, Liu M Abstract The inflammatory response and apoptosis are key factors in cerebral ischemia‑reperfusion injury. The severity of the inflammatory reaction and apoptosis has an important impact on the prognosis of stroke. The ultrasmall superparamagnetic iron oxide particle has provided an effective magnetic resonance molecular imaging method for dynamic ...
Source: Molecular Medicine - February 20, 2021 Category: Molecular Biology Authors: Zhuang L, Kong Y, Yang S, Lu F, Gong Z, Zhan S, Liu M Tags: Mol Med Rep Source Type: research

Dynamic changes of inflammation and apoptosis in  cerebral ischemia‑reperfusion injury in mice investigated by ferumoxytol‑enhanced magnetic resonance imaging
Mol Med Rep. 2021 Apr;23(4):1-13. doi: 10.3892/mmr.2021.11921. Epub 2021 Feb 19.ABSTRACTThe inflammatory response and apoptosis are key factors in cerebral ischemia‑reperfusion injury. The severity of the inflammatory reaction and apoptosis has an important impact on the prognosis of stroke. The ultrasmall superparamagnetic iron oxide particle has provided an effective magnetic resonance molecular imaging method for dynamic observation of the cell infiltration process in vivo. The aims of the present study were to investigate the inflammatory response of cerebral ischemia‑reperfusion injury in mice using ferumoxytol‑...
Source: Molecular Medicine Reports - February 19, 2021 Category: Molecular Biology Authors: Lihua Zhuang Yingnan Kong Shuohui Yang Fang Lu Zhigang Gong Songhua Zhan Mengxiao Liu Source Type: research

Development of L-carnosine functionalized iron oxide nanoparticles loaded with dexamethasone for simultaneous therapeutic potential of blood brain barrier crossing and ischemic stroke treatment.
Authors: Lu X, Zhang Y, Wang L, Li G, Gao J, Wang Y Abstract The development of suitable drug delivery carriers is significant in biomedical applications to improve the therapeutic efficiency. Recent progress in nanotechnological fields, paved the way for the formulation of variety of drug carriers. The brain disorders such as ischemic stroke, brain cancer, and CNS disorders were poorly treated due to the presence of blood brain barrier that hinders the passage of drugs to the brain. Hence, the formulated drugs should have the ability to cross the blood-brain barrier (BBB) for ischemic stroke treatment. In the pres...
Source: Drug Delivery - February 17, 2021 Category: Drugs & Pharmacology Tags: Drug Deliv Source Type: research