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Source: Journal of the Neurological Sciences

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Total 856 results found since Jan 2013.

Mechanical thrombectomy for acute large vessel occlusion stroke beyond 24  h
In this study, we aimed to determine the safety and efficacy of endovascular stroke therapy in this late window.
Source: Journal of the Neurological Sciences - March 2, 2023 Category: Neurology Authors: Abhi Pandhi, Rahul Chandra, Mohammad A. Abdulrazzak, Anas Alrohimi, Ashutosh Mahapatra, Mark Bain, Nina Moore, M. Shazam Hussain, Jennifer Bullen, Gabor Toth Source Type: research

Mechanical thrombectomy for acute large vessel occlusion stroke beyond 24  h
In this study, we aimed to determine the safety and efficacy of endovascular stroke therapy in this late window.
Source: Journal of the Neurological Sciences - March 2, 2023 Category: Neurology Authors: Abhi Pandhi, Rahul Chandra, Mohammad A. Abdulrazzak, Anas Alrohimi, Ashutosh Mahapatra, Mark Bain, Nina Moore, M. Shazam Hussain, Jennifer Bullen, Gabor Toth Source Type: research

Is improved access to magnetic resonance imaging imperative for optimal ischemic stroke care?
Neuroimaging, including CT and MRI, is integral to ischemic stroke (IS) treatment, management, and prevention. However, the use of MRI for IS patients is limited despite its potential to provide high-quality images that yield definitive information related to the management of IS. MRI is beneficial when the information provided by CT is insufficient for decisions related to the diagnosis, etiology, or treatment of IS. In the emergency setting, MRI can improve the diagnostic accuracy of CT-negative acute ischemic strokes (AIS) and ensure a better selection of patients for reperfusion therapies with thrombolysis and/or thrombectomy.
Source: Journal of the Neurological Sciences - February 17, 2023 Category: Neurology Authors: Mukesh Kumar, Sherry Hu, Steven Beyea, Noreen Kamal Tags: Clinical short communication Source Type: research

Modification of the effects of age on clinical outcomes through management of lifestyle-related factors in patients with acute ischemic stroke
This study examined the association between age and clinical outcomes after ischemic stroke, and whether the effect of age on post-stroke outcomes can be modified by various factors.
Source: Journal of the Neurological Sciences - February 14, 2023 Category: Neurology Authors: Yuichiro Ohya, Ryu Matsuo, Noriko Sato, Fumi Irie, Yoshinobu Wakisaka, Tetsuro Ago, Masahiro Kamouchi, Takanari Kitazono, Investigators for Fukuoka Stroke Registry Source Type: research

Interhemispheric parietal cortex connectivity reflects improvement in post-stroke spasticity due to treatment with botulinum toxin-A
In post-stroke spasticity (PSS), effective treatment with botulinum neurotoxin (BoNT) is associated with transient decrease in activation of the ipsilesional superior parietal lobule (SPL) and intraparietal sulcus (IPS). We hypothesized that this would be reflected in changes in resting-state functional connectivity (rsFC) of the SPL/IPS. Our aim was therefore to assess rsFC of the ipsilesional SPL/IPS in chronic stroke patients with hemiparesis both with and without PSS and to explore the relationship between SPL/IPS rsFC and PSS severity.
Source: Journal of the Neurological Sciences - February 14, 2023 Category: Neurology Authors: Tom áš Veverka, Pavel Hok, Markéta Trnečková, Pavel Otruba, Jana Zapletalová, Zbyněk Tüdös, Martin Lotze, Petr Kaňovský, Petr Hluštík Source Type: research

Atherosclerotic carotid plaque characteristics vary with time from ischemic event: A multicenter, prospective magnetic resonance vessel wall imaging registry study
Recent studies report that the rate of recurrent stroke is highest in the stages immediately following cerebral infarction and decreases over time in patients with atherosclerotic carotid stenosis. The purpose of this study was to identify temporal differences in early stage carotid plaque components from acute cerebrovascular ischemic events using carotid MRI. Carotid plaque images were obtained on 3  T MRI from 128 patients enrolled in MR-CAS. Among the 128 subjects, 53 were symptomatic and 75 asymptomatic.
Source: Journal of the Neurological Sciences - February 7, 2023 Category: Neurology Authors: Manabu Shirakawa, Kiyofumi Yamada, Hiroko Watase, Baocheng Chu, Yukiko Enomoto, Takao Kojima, Kazuki Wakabayashi, Jie Sun, Daniel S. Hippe, Marina S. Ferguson, Niranjan Balu, Shinichi Yoshimura, Thomas S. Hatsukami, Chun Yuan Source Type: research

Simple CaroTID-VasC score to predict one-year risk of stroke in symptomatic carotid stenosis patients
A subset of extracranial symptomatic carotid stenosis (ESCS) patients may fare well on current optimal medical therapy (OMT), and surgery may be avoided in these patients. Therefore, we aimed to develop and validate a stroke risk prediction model to stratify the risk among ESCS patients.
Source: Journal of the Neurological Sciences - January 30, 2023 Category: Neurology Authors: Mukesh Kumar, Dheeraj Khurana, Chirag Kamal Ahuja, Ashok Kumar, Baljinder Singh, Manju Mohanty Source Type: research

Safety outcomes of early initiation of antithrombotic agents within 24  h after intravenous alteplase at 0.6 mg/kg
We examined outcome of acute ischemic stroke (AIS) with administration of antithrombotics within 24  h after intravenous low-dose alteplase.
Source: Journal of the Neurological Sciences - January 6, 2023 Category: Neurology Authors: Tetsuya Chiba, Takeshi Yoshimoto, Shinichi Wada, Masayuki Shiozawa, Sohei Yoshimura, Shunsuke Kimura, Manabu Inoue, Kazunori Toyoda, Masafumi Ihara, Masatoshi Koga Source Type: research

Safety outcomes of early initiation of antithrombotic agents within 24  h after intravenous alteplase at 0.6 mg/kg
We examined outcome of acute ischemic stroke (AIS) with administration of antithrombotics within 24  h after intravenous low-dose alteplase.
Source: Journal of the Neurological Sciences - January 6, 2023 Category: Neurology Authors: Tetsuya Chiba, Takeshi Yoshimoto, Shinichi Wada, Masayuki Shiozawa, Sohei Yoshimura, Shunsuke Kimura, Manabu Inoue, Kazunori Toyoda, Masafumi Ihara, Masatoshi Koga Source Type: research

Comparative efficacy and safety of tenecteplase and alteplase in acute ischemic stroke: A pairwise and network meta-analysis of randomized controlled trials
Studies on tenecteplase have been yielding mixed results on several important variables at different doses, thus hampering objective guideline recommendations in acute ischemic stroke management. This meta-analysis stratifies doses in order to refine our interpretation of outcomes and quantify the benefits and harms of tenecteplase at different doses.
Source: Journal of the Neurological Sciences - December 28, 2022 Category: Neurology Authors: Aqeeb Ur Rehman, Aleenah Mohsin, Huzaifa Ahmad Cheema, Afra Zahid, Muhammad Ebaad Ur Rehman, Muhammad Zain Ameer, Muhammad Ayyan, Muhammad Ehsan, Abia Shahid, Muhammad Aemaz Ur Rehman, Jaffer Shah, Ayaz Khawaja Tags: Review Article Source Type: research

Visual suppression of vestibulo-ocular reflex in patients treated with carotid artery revascularization: A potential biomarker for cerebral perfusion
Carotid endarterectomy (CEA) and carotid artery stenting (CAS) are common treatments for ischemic stroke prevention in patients with carotid artery stenosis. However, the beneficial effects of CEA/CAS for cerebral hypoperfusion due to carotid artery stenosis have yet to be fully established. As dizziness is a common symptom in patients with carotid artery stenosis, we aimed to evaluate the effects of CEA/CAS on cerebral function in patients with carotid artery stenosis, using equilibrium function tests.
Source: Journal of the Neurological Sciences - December 25, 2022 Category: Neurology Authors: Shigeta Miyake, Koji Takahashi, Yasunobu Nakai, Yu Amano, Ryoo Yamamoto, Kazumitsu Amari, Hiroya Hara, Ken Johkura Source Type: research

Intracranial artery stenosis is associated with cortical thinning in stroke-free individuals of two longitudinal cohorts
We examined the association between asymptomatic intracranial artery stenosis (aICAS) and cortical thickness using brain magnetic resonance morphometry in two cohorts.
Source: Journal of the Neurological Sciences - December 22, 2022 Category: Neurology Authors: Dixon Yang, Arjun V. Masurkar, Farid Khasiyev, Tatjana Rundek, Clinton B. Wright, Mitchell S.V. Elkind, Ralph L. Sacco, Jose Gutierrez Source Type: research

Stroke mortality prediction using machine learning: systematic review
Accurate prognostication of stroke may help in appropriate therapy and rehabilitation planning. In the past few years, several machine learning (ML) algorithms were applied for prediction of stroke outcomes. We aimed to examine the performance of machine learning –based models for the prediction of mortality after stroke, as well as to identify the most prominent factors for mortality.
Source: Journal of the Neurological Sciences - December 20, 2022 Category: Neurology Authors: Lihi Schwartz, Roi Anteby, Eyal Klang, Shelly Soffer Tags: Review Article Source Type: research

Stroke mortality prediction using machine learning: A systematic review
Accurate prognostication of stroke may help in appropriate therapy and rehabilitation planning. In the past few years, several machine learning (ML) algorithms were applied for prediction of stroke outcomes. We aimed to examine the performance of machine learning –based models for the prediction of mortality after stroke, as well as to identify the most prominent factors for mortality.
Source: Journal of the Neurological Sciences - December 20, 2022 Category: Neurology Authors: Lihi Schwartz, Roi Anteby, Eyal Klang, Shelly Soffer Tags: Review Article Source Type: research

Combination of heart rate variability and ABCD2 score portends adverse outcomes after minor stroke or transient ischemic attack
The residual recurrent risk of stroke, which cannot be entirely explained by the traditional ABCD2 score, still existed. Heart rate variability (HRV), a method for reflecting the function of automatic nervous system (ANS), was a novel predictor of secondary stroke events. We aimed to investigate relationships of combined heart rate variability (HRV) and ABCD2 score with adverse outcomes after acute minor stroke (MS) or transient ischemic attack (TIA), and further investigate the independent associations between HRV and adverse outcomes after MS/TIA stratified by ABCD2 score.
Source: Journal of the Neurological Sciences - December 11, 2022 Category: Neurology Authors: Yu Tian, Yuesong Pan, Mengxing Wang, Xia Meng, Zhao Xingquan, Liping Liu, Yongjun Wang, Yilong Wang Source Type: research